Gene 13023 (Tetrahymena)

13023

Species: Tetrahymena
Alias: TTHERM_00058380, 4.m00422, PreTt13023, 463, 13023, 3707.m00067
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E5

Sequence

Name Sequence Type Origin Length Description Download
13023.AA Protein None 584 None Fasta, JSON
13023.kin_dom Protein Kinase Domain None 83 None Fasta, JSON
13023.NA RNA None 1755 None Fasta, JSON

Protein domain

Protein domains of 13023.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13023.AA Ciliate-E5 50-132 59 3.2e-52 168.16 In-house 1-84 (271) Show / Hide 
Range on Protein: 50-132
Range on HMM: 1-84/271
Sequence Identity: 59% (50 aa)

IVENGFLGMGGSALVMKACSEENDYLAIKFI-INPSQAQVKACQQEFQILSQFNSPHIIKVYDIIQEQYEQMNYQILIMERCAC
|.||..||.|||..|||.|||.||......| ....|.|....|.||.||.|||||||||||.|.|.|||.||||..|||||.|
IIENQILGKGGSGMVMKGCSEWNDKPIAIKIMKCKNQKQCEDNQREFNILKQFNSPHIIKVYQIYQYQYENMNYQFIIMERCKC
Kinase 13023.AA Ciliate-E5 168-210 46 1.2e-23 73.62 In-house 212-271 (271) Show / Hide 
Range on Protein: 168-210
Range on HMM: 212-271/271
Sequence Identity: 46% (28 aa)

NMEGFTAQYSSPEQYQLANCHS-----------------KKSITKSSDIYSLGLVFMQLT
| .|||..||||||||. .  .                 || |||.|||||||.||..||
NLKGFTQCYSSPEQYQCYHNQMFYILIRNLPDIKYIQSFKKKITKQSDIYSLGIVFLELT
Kinase 13023.AA Ciliate-A1 171-268 22 6.3e-18 57.56 In-house 180-301 (301) Show / Hide 
Range on Protein: 171-268
Range on HMM: 180-301/301
Sequence Identity: 22% (27 aa)

GFTAQYSSPEQYQLAN---CHSKKSITKSSDIYSLGLVFMQLTG-----------VDISQKWVFSEK----------LNGGNYDKCLNPNYEQFNTIIKQ
| .  | ||||||.       ..  | | ||.||||.... |..           | |       ..          .  ...    .| .|. . .|..
GGNLYYMSPEQYQMHYRDQMFIENKIYKQSDMYSLGCIICFLCYKEDSHPYVGTIVNIFGNNMQNDQSIHFCKSVNAIKKIIFPPMQEPRFEELQNLIFK

MVCYEPEQRLEINAVVLKIKQI
|  |||..|.    ..   ...
MMQYEPNNRCSLQQCIDCLYIF
Kinase 13023.AA S_TKc 50-269 15 1.3e-11 -6.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-269
Range on HMM: 1-231/231
Sequence Identity: 15% (41 aa)

IVENGFLGMGGSALVMKACSEE-NDYLAIKFIINPSQAQVKACQQEFQILSQFNSPHIIKVYDIIQEQYEQMNYQILIMERCAC---QVWSLPKDQEI--
      .| |. . |.|.   . . . ||| |        .  ..| |||.. . |.|.| ||..|.     ..  ..|| |      . .. |..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--CILKISCIQILSQEIFC--------------------------------LALIQNGNMEGFTAQYSSPEQYQLANCHSKKSITK-SSDIYSLGLVFMQ
  . .    .. . ..|.|                                || .   .    |  | .||           . .| ..|..|.| ..  
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILYE

LTG----VDISQKWVFSEKLNGGNYDKCLNPNYEQFNTIIKQMVCYEPEQRLEINAVVL-----KIKQII
.       .  |  .  .|.             ...  .|... ...||.|. .  .       |. . .
MLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13023.AA Ciliate-B2 165-203 42 5.5e-11 21.98 In-house 158-197 (197) Show / Hide 
Range on Protein: 165-203
Range on HMM: 158-197/197
Sequence Identity: 42% (17 aa)

QNGNMEGFTAQYSSPEQYQLA-NCHSKKSITKSSDIYSLG
|. .  ||| .| |||| .   |  .   |   |||||.|
QQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 13023.AA CAMKL 49-128 25 1.6e-10 29.64 In-house 1-101 (297) Show / Hide 
Range on Protein: 49-128
Range on HMM: 1-101/297
Sequence Identity: 25% (26 aa)

YIVENGFLGMGGSALVMKACS-EE-NDYLAIKFII------NPSQAQVKA---------CQQEFQILSQFN---SPHIIKVYDII-QEQY--EQMNYQIL
|...   || |. . |  |.     .   |||.|       .|   . |           ..| ||....|    |.||| |..|  ...  |  ..  |
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYL

IME
.||
VME
Kinase 13023.AA Ciliate-A1 49-130 28 5.7e-10 30.07 In-house 1-83 (301) Show / Hide 
Range on Protein: 49-130
Range on HMM: 1-83/301
Sequence Identity: 28% (24 aa)

YIVENGFLGMGGSALVMKACSEENDY--LAIKFIINPSQAQVKACQQEFQILSQFNSPHIIKVYDIIQEQYEQMNYQILIMERC
| |.   .. |.   ||.|   .|    |..| ||     | |   ||.... | |..  ||.|. .. . .    . .||| |
YHVVQ-LIDKGSFGVVMRAYDIQNQKKYLCCKIIICTNFEQYKNNIQEYRKCKQINHNNVIKNYQQLYYNTNNKECMFIIMEYC
Kinase 13023.AA CAMK 55-130 14 5e-09 24.47 In-house 1-142 (425) Show / Hide 
Range on Protein: 55-130
Range on HMM: 1-142/425
Sequence Identity: 14% (21 aa)

FLGMGGSALVMKACSEEN-------------DYLAIKFIINP----------------------------SQAQVKACQQEFQILSQ-------FNSPHI
 || |. . | ...  ..                |||.|                               ..   |  ..| .|...        . |.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKVYDIIQ---------EQYEQMNY--------QILIM---ERC
|| |....         . ||  ..         ...|   | |
IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYC
Kinase 13023.AA CMGC 50-160 15 9.7e-09 23.88 In-house 1-191 (513) Show / Hide 
Range on Protein: 50-160
Range on HMM: 1-191/513
Sequence Identity: 15% (30 aa)

IVENGFLGMGGSALVMKACS---------------EENDYLAIKFIINPSQAQVKAC------------QQEFQILSQFN-----------------SPH
    . .| |  . | |.                 | | . ||| | ||   .  |.            . | .|| ..|                  ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIKVYDIIQEQYEQ-------------MNYQILIMERCACQVWSLPKDQE--------------------------ICILKISCIQILSQEIFC
|.| |||..   ..             .|.  |..| . .  . . |..                           |. . | .|.  .. |..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILR
Kinase 13023.AA ULK 50-128 23 3.7e-08 25.11 In-house 1-97 (324) Show / Hide 
Range on Protein: 50-128
Range on HMM: 1-97/324
Sequence Identity: 23% (23 aa)

IVENGFLGMGGSA-LVMKACSEEN----DYLAIKFIINPSQAQVK----------ACQQEFQILSQFN---SPH--IIKVYDIIQEQYEQMNYQILIME
.. |  || |  .  | |.  ...     | |.| |   .. . |            ..| ||. ...   .|.  |.| ||. ... .  |.  .|||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH--NNIYIIME
Kinase 13023.AA Ciliate-E3 171-210 42 1.5e-07 19.94 In-house 169-202 (202) Show / Hide 
Range on Protein: 171-210
Range on HMM: 169-202/202
Sequence Identity: 42% (17 aa)

GFTAQYSSPEQYQLANCHSKKSITKSSDIYSLGLVFMQLT
|.|  |..||| . ..      | | ||.||.| ||.|| 
GWTPFYAAPEQNDQQQ------ISKESDYYSVGAVFCQLC
Kinase 13023.AA Ciliate-E3 49-120 34 1.7e-07 19.78 In-house 1-78 (202) Show / Hide 
Range on Protein: 49-120
Range on HMM: 1-78/202
Sequence Identity: 34% (27 aa)

YIVENGFLGMGGSALVMKACS-EENDYLAIKFIINPSQAQ------VKACQQEFQILSQFNSPHIIKVYDIIQEQYEQM
| |    || |.  .| || .   |   ||| ||   |.       ..  |||||  .|.|| .. |..|..  |  .|
YTVQQ-ILGCGQFGRVYKAFDFQNNQDVAIKAIICQNQQNEGVGEQFQKTQQEFQNCQQINSQNVVKCHDQYYDQQNKM
Kinase 13023.AA Ciliate-E1 158-200 28 1.7e-05 14.37 In-house 158-202 (202) Show / Hide 
Range on Protein: 158-200
Range on HMM: 158-202/202
Sequence Identity: 28% (13 aa)

IFCLALIQNGNMEGFTAQYSSPEQYQ---LANCHSKKSITKSSDIY
....  .|. . .|.|  |..||||.   . .   .. |.. ||||
FLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY
Kinase 13023.AA Ciliate-C8 59-133 20 2.7e-05 15.32 In-house 1-101 (238) Show / Hide 
Range on Protein: 59-133
Range on HMM: 1-101/238
Sequence Identity: 20% (21 aa)

GGSALVMKA-CSEENDYLAIKFIIN---PSQAQVKACQQEFQILSQFN-SPHIIKVYD--IIQEQYEQMN-----------------YQILIMERCA--C
|. ..|.||  . .| . |.||.       ..| .  ..|   . ||  .| ...|||  ...|. ..                   .  . || |   |
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC

Q
.
N
Kinase 13023.AA Pkinase 50-132 22 5.8e-05 18.62 Pfam 1-84 (293) Show / Hide 
Range on Protein: 50-132
Range on HMM: 1-84/293
Sequence Identity: 22% (20 aa)

IVENGFLGMGGSALVMKACSEENDY-LAIKFIINPSQAQVKACQQ-----EFQILSQFNSPHIIKVYDIIQEQYEQMNYQILIMERCAC
..  . .| |... | |..   .    |.| |  .  .  . .|.     | ||.  .|.|.|.. ||. ..  ..  |  ..|| | .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIY--MVMEYCEG
Kinase 13023.AA Ciliate-C8 173-206 32 8.1e-05 13.58 In-house 205-238 (238) Show / Hide 
Range on Protein: 173-206
Range on HMM: 205-238/238
Sequence Identity: 32% (11 aa)

TAQYSSPEQYQLANCHSKKSITKSSDIYSLGLVF
.  |. ||...  . .  .  .| ||.||.|||.
NWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 13023.AA Ciliate-E1 56-133 22 0.000202 10.84 In-house 1-82 (202) Show / Hide 
Range on Protein: 56-133
Range on HMM: 1-82/202
Sequence Identity: 22% (19 aa)

LGMGGSALVMKACSEEND-YLAIKFIINPSQAQV-----KACQQEFQILSQFNSPHIIKVYDIIQEQY-EQMNYQILIMERCACQ
.| |....| || ...|  .  .. |||  ....     .  .....|.. |..   .....||. .. .| . .|.|.| | |.
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKK--ECYIIQIIDYIKIDQNYICIIIFECCCCS
Kinase 13023.AA Ciliate-B2 49-132 25 0.000347 5.63 In-house 1-85 (197) Show / Hide 
Range on Protein: 49-132
Range on HMM: 1-85/197
Sequence Identity: 25% (23 aa)

YIVENGFLGMGGSALVMKAC---S-EENDYLAIKFIINPSQAQVKACQQEFQILSQFN-SPHIIKVYDIIQEQYEQMNYQILIMERCAC
|.  . ... ||  .. .     | .|   ||.|   |  ... .  |.| .|.. |. . ...|. | ||    . . ..||||.| |
YYLCK-YINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMFEYNINVVKYIDHIQ---INETIDVLIMEKCEC
Kinase 13023.AA Pkinase 173-209 18 0.463815 4.83 Pfam 174-205 (293) Show / Hide 
Range on Protein: 173-209
Range on HMM: 174-205/293
Sequence Identity: 18% (7 aa)

TAQYSSPEQYQLANCHSKKSITKSSDIYSLGLVFMQL
|  | .||  .     . . .....|..|.|... ..
TPWYMAPEVIR-----GGQYYGPKVDMWSCGCILYEM