Gene 5933 (Tetrahymena)
5933
Group:
Other
Family:
Ciliate-E4
Sequence
Protein domains of 5933.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 5933.AA | Ciliate-E4 | 21-39 | 47 | 0.007847 | 5.92 | In-house | 1-19 (150) | Show / Hide |
Range on Protein: 21-39 Range on HMM: 1-19/150 Sequence Identity: 47% (9 aa) YSFIEDKQDLHYGQIKVFE | || .|.||| | . | YRKIESVKDIHYGDIQIME |
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| Kinase | 5933.AA | Ciliate-E4 | 110-204 | 50 | 2.1e-60 | 199.07 | In-house | 56-150 (150) | Show / Hide |
Range on Protein: 110-204 Range on HMM: 56-150/150 Sequence Identity: 50% (48 aa) KNLIDVYEYFIQTEEKFCSSVQRIQLVIEYLQRDIQIEVKTKKLQNQRFTPQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEYFEIKLLH .|.|.|||||...|..||||..|.....||||.|.|...|..|.|.|.|...||..|||.|||..|.||.||..|||||.|||....||..|.. ENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQQGQHFDESEIWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD |
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| Kinase | 5933.AA | Ciliate-A5 | 110-330 | 25 | 3.8e-26 | 87.65 | In-house | 46-275 (275) | Show / Hide |
Range on Protein: 110-330 Range on HMM: 46-275/275 Sequence Identity: 25% (60 aa) KNLIDVYEYFIQTEEKFCSSVQRIQLVIEYLQRDIQIEVKTKKLQN--QRFTPQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEYFEIKLLHPLV .|.. .. . . .| |||. .. .. || . . |. | . ... ||...|... |. .. || |. |||.. .||.... ..|| . PNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNEQELWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKLMD--M NKIVPSFA--TMISQLSYGEHFDTQG-IYLSPLLTKAVSQKN----YQPQHNPFKSDVFTLGIILIECCNLGTV-DNLYNYEAGDFNEN-QLKIHMNIIK | .| | | .| .|. ||||.. .. . .| || .|||||.|| |. |.| . . . | || .| .|. . . NESKDFFYQINWSSYKQYQHHMSTENKQYLSPMQWYQMMHRDEQNIQRPEHNWYKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKE NQYGVDVHDLIARMVKVQEQDRPDFIELATQL |. ..|..| | .||||.... .| KKYSEQFINFIKQMLQFEENKRPDFHQIYQYL |
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| Kinase | 5933.AA | Ciliate-B2 | 135-197 | 25 | 6.4e-09 | 17.0 | In-house | 78-140 (197) | Show / Hide |
Range on Protein: 135-197 Range on HMM: 78-140/197 Sequence Identity: 25% (16 aa) LVIEYLQRDIQIEVKTKKLQNQRFTPQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEY |..| . . . |.. ..| . |. | .. . | |. | . . | | |.| .|||.... LIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQN |
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| S_TKc | 5933.AA | S_TKc | 80-333 | 15 | 8.3e-08 | -62.44 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 80-333 Range on HMM: 1-231/231 Sequence Identity: 15% (44 aa) YQDLDTI---------------DKDLVNMKQLIHITEENHKEKRTKNLIDVYEYFIQTEEKFCSSVQRIQLVIEYLQR---DIQIEVKTKKLQNQR--FT |. |..| .. .| .|.. | .| . .. .. . | . ... .| ||. | | .. . | |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP PQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEYFEIKL--------LHPLVNKIVPSFATMISQLSYGEHFDTQGIYLSP-LLTKAVSQKNYQPQ . .. .. .. | . . | ||| .|||..| .||. | .| |..| .| . E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------TTFCGTPWYMAPEVL-----------G HNPFKSDVFTLGIILIECCNLGTV--DNLYNYEAGDFNENQLKIHMNIIKNQYGVDVHDLIARMVKVQEQDRPDFIELAT------QLNII ....|.|. .|.||.|.. | . .. .. .| .. |.| .. .. ..|| |. . . . YGKCKCDWWSCGCILYEMLC-GYPPFP------------QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 5933.AA | Ciliate-E1 | 97-259 | 17 | 4e-06 | 16.52 | In-house | 36-202 (202) | Show / Hide |
Range on Protein: 97-259 Range on HMM: 36-202/202 Sequence Identity: 17% (30 aa) IHITEENHKEKRTKNLIDVYEYFIQTEEKFC-SSVQRIQLVIEYLQRDIQIEVK---------TKKLQNQRFTPQEIFTIAFSCINSLYNLQLVNLAHGD .|...|..... .. . ..| || . . . . . ...|... . . . .. ... || |.. |.| | | |. |. |.| NHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRD LKTSNILVSEYFEIKLLHPLVNKIVPSFATMISQLSYGEHFDTQGIYLSPLLTKAVSQKNYQPQHNPFKSDVF .| .|||.. . .. .. .. | . .|... . . | .| . . |. ...| .|||.. IKPQNILINNQ-GNYVYC----DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY |
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| Kinase | 5933.AA | Dicty4-Unclassified | 163-201 | 38 | 0.000439 | 9.84 | In-house | 111-149 (263) | Show / Hide |
Range on Protein: 163-201 Range on HMM: 111-149/263 Sequence Identity: 38% (15 aa) IFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEYFEIK | .||. . | .|. | |.| ||||. | || IIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIK |
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| Kinase | 5933.AA | Ciliate-C8 | 87-265 | 17 | 0.00044 | 10.92 | In-house | 28-238 (238) | Show / Hide |
Range on Protein: 87-265 Range on HMM: 28-238/238 Sequence Identity: 17% (37 aa) DKDLVNMKQLIHITEENHKEKRTKNLIDVYEYFIQTEEKFCSS-------------VQRIQLVIEYLQRD----IQIEVKTKKLQNQRFTPQEIFTIAFS ... . |...| | . .. ...|| .|. .||. .... |.| . . .. . ... .. |. . || KIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNCNLKQYFDRCRKKQSYPSQQMKEIIAIQ CINSLYNLQLVNLAHGDLKTSNILVSEY----FEIKLL-------HPLVNKIVPSFATMISQLSYGEHFDTQGI------YLSPLLTKAVSQKNYQPQHN | |. .| | | | | .|.||.. ..||| . .. . ..|. |. ... | | . | .| ... . MIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQS--DIF PFKSDVFTLGIIL .|||.. .|..| SKKSDSYSVGLVL |
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| Kinase | 5933.AA | VPS15 | 166-195 | 38 | 0.000533 | 9.88 | In-house | 103-133 (296) | Show / Hide |
Range on Protein: 166-195 Range on HMM: 103-133/296 Sequence Identity: 38% (12 aa) IAFSCINSLYNLQLVN-LAHGDLKTSNILVS ||| . |. .. . |||.|..||||. IAFQTLCALEQCHKQGNVCHGDIKSENILVT |
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| Kinase | 5933.AA | Ciliate-C3 | 181-205 | 48 | 0.000605 | 10.5 | In-house | 116-140 (140) | Show / Hide |
Range on Protein: 181-205 Range on HMM: 116-140/140 Sequence Identity: 48% (12 aa) NLAHGDLKTSNILVSEYFEIKLLHP |. |||.| ||||. |||.. NIVHGDIKFSNILINSKDEIKIIDF |
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| Kinase | 5933.AA | Ciliate-B2 | 254-262 | 44 | 0.001445 | 4.14 | In-house | 189-197 (197) | Show / Hide |
Range on Protein: 254-262 Range on HMM: 189-197/197 Sequence Identity: 44% (4 aa) FKSDVFTLG |.||.. .| FQSDIYSMG |
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| Kinase | 5933.AA | TKL-Unique | 174-202 | 33 | 0.002579 | 7.76 | In-house | 123-158 (290) | Show / Hide |
Range on Protein: 174-202 Range on HMM: 123-158/290 Sequence Identity: 33% (12 aa) LYNLQLVN--LAHGDLKTSNILVSEY-----FEIKL .|.| . .|.|||.||.||.. . ||. MYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKI |
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| Kinase | 5933.AA | C8 | 117-202 | 28 | 0.010788 | 5.31 | In-house | 84-168 (226) | Show / Hide |
Range on Protein: 117-202 Range on HMM: 84-168/226 Sequence Identity: 28% (26 aa) EYFIQTEEKFCSSVQRIQLVIEYLQRDIQIEVKTKKLQNQRFTPQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILV----SEYFEIKL | .||||| | .|. ..| .. .. . .. ..| |. .. . || | .. .... | | |.| .|.|| .. ||||| EKIVQTEEKSC-FVMEMELC----EQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKL |
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| Kinase | 5933.AA | C8 | 255-265 | 45 | 0.013926 | 4.92 | In-house | 216-226 (226) | Show / Hide |
Range on Protein: 255-265 Range on HMM: 216-226/226 Sequence Identity: 45% (5 aa) KSDVFTLGIIL .||.| .|..| QSDLFSVGLVL |
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| Kinase | 5933.AA | TKL-Unique | 255-268 | 57 | 0.044284 | 3.35 | In-house | 208-221 (290) | Show / Hide |
Range on Protein: 255-268 Range on HMM: 208-221/290 Sequence Identity: 57% (8 aa) KSDVFTLGIILIEC ||||. ||.|.|. KSDVYSFGIVLWEI |
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| MORN | 5933.AA | MORN | 948-970 | 47 | 4e-06 | 26.97 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 948-970 Range on HMM: 1-23/23 Sequence Identity: 47% (11 aa) YEGEWCEGRMEGLGTLYYPSGSL ||||| .|.|.| |....|.|. YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 5933.AA | MORN | 925-947 | 39 | 0.000143 | 21.35 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 925-947 Range on HMM: 1-23/23 Sequence Identity: 39% (9 aa) YIGEKLGGLRHGTGKFFYADGGY | || .|..|| |.. ..||.. YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 5933.AA | MORN | 946-967 | 36 | 0.000281 | 20.95 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 946-967 Range on HMM: 1-22/22 Sequence Identity: 36% (8 aa) GYYEGEWCEGRMEGLGTLYYPS ||||| .|.. | |...... DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 5933.AA | MORN | 923-944 | 40 | 0.000346 | 20.27 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 923-944 Range on HMM: 1-22/22 Sequence Identity: 40% (9 aa) SHYIGEKLGGLRHGTGKFFYAD ..|.|| |.||| |.. .|. DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 5933.AA | MORN | 970-991 | 27 | 0.000947 | 17.0 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 970-991 Range on HMM: 1-22/22 Sequence Identity: 27% (6 aa) LAYLGQWRNDQFNGKGTVYNES | |.|.|... |.|. . . DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 5933.AA | MORN | 972-986 | 40 | 0.006287 | 15.39 | Pfam | 1-15 (23) | Show / Hide |
Range on Protein: 972-986 Range on HMM: 1-15/23 Sequence Identity: 40% (6 aa) YLGQWRNDQFNGKGT | |.|.|....|.|. YEGEWKNGKMHGHGV |
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| MORN | 5933.AA | MORN | 1014-1036 | 39 | 4.7e-05 | 23.11 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 1014-1036 Range on HMM: 1-23/23 Sequence Identity: 39% (9 aa) YEGDFKDDNKEGIGTIYLSNGDR |||..|.. ..| |. . ..||| YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 5933.AA | MORN | 1035-1056 | 40 | 0.003105 | 13.14 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 1035-1056 Range on HMM: 1-22/22 Sequence Identity: 40% (9 aa) DRFTGNFNNDFVHGQGTYFREN || .|.. |. ||.|.| . | DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 5933.AA | MORN | 1012-1033 | 27 | 0.00508 | 11.54 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 1012-1033 Range on HMM: 1-22/22 Sequence Identity: 27% (6 aa) VKYEGDFKDDNKEGIGTIYLSN .|||..... . | |. . .| DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 5933.AA | MORN | 1037-1052 | 37 | 0.068705 | 11.62 | Pfam | 1-16 (23) | Show / Hide |
Range on Protein: 1037-1052 Range on HMM: 1-16/23 Sequence Identity: 37% (6 aa) FTGNFNNDFVHGQGTY . |.. |.. ||.|.| YEGEWKNGKMHGHGVY |
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