Gene 7935 (Tetrahymena)
7935
Sequence
Protein domains of 7935.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 7935.AA | Ciliate-E2-Unclassified | 13-272 | 26 | 3.3e-93 | 315.97 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-352/352 Sequence Identity: 26% (95 aa) YSESNELGSGAFAQVFKGINKQTNTDV-----AIKVISRQ-KLKKYGEEIINAIGDEVNILQKLSFLS----------QKDPCPFIVKIFDCFQTTNNIY | .|.|.|..|.| ..|... . ..|.... |.... . .|. . .|.|...| .. . . |.||||| |.|||...||| YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY IILEYCNGGNLLDIIKKCPQ----------------GIPEQQAI-----KIFYQIVSGI-NYIAKHDIVHRDLKPENIFIHDG----VYKIGDFGFAS-- |..|||.||.|...|||... ..||||. ..|.||..|. .. |..|.|||.|||||..... || |||... IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY -----------------QKNMFYTTLGTYPYM----APEFFKDPSYD----KLVDIWAVGIMYHEMLFNELYFMGNSQYE----------------VSQK ...|..|. ||. || ||| .. || . .|||..|. .||||... | .|.... . |. QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN ICNVPYKIVRPNM------ISPNSQDVLI----KCIEKDRSVRITADQLINHPLF |.. .... . .||. .| . |...|. . |||..|..|||.| IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 7935.AA | ULK | 13-272 | 33 | 9.6e-89 | 301.13 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-324/324 Sequence Identity: 33% (109 aa) YSESNELGSGAFA-QVFKGINKQT---NTDVAIKVISRQKLKKYGEE-----IINAIGDEVNILQKLSFLSQKDPCPF--IVKIFDCFQTT--NNIYIIL |. ...||.|.|. .|.||.||.| | .||.|.|...|..| | ... . |..|..|| |. .|. ||| .|.|.|. ||||||. YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELK----HPNHHIVKLYDWFETSNHNNIYIIM EYCNGGNLLDIIK---KCP-----QGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIHDG-------------VYKIGDFGFASQKN------- ||||||.| ..|| |.| . ..||.||..|.||..| .. || |.|||.||.|| ||.| |.||.||||| . . EYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQ MFYTTL------GTYPYMAPEFFKDP----SYD-KLVDIWAVGIMYHEMLFNELYFMGNSQYEVSQK--------------ICNVPYKIVRPN---MISP |..|.. || ||||. ... |. . .||| .|....|||... .| .. .. .. |.| | .. |. ||| MCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISP NSQDVLIKCIEKDRSVRITADQLINHPLF ...| . .....|.. ||. ....|||.| ECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | 7935.AA | Ciliate-E2 | 13-272 | 25 | 1.5e-88 | 300.52 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-365/365 Sequence Identity: 25% (96 aa) YSESNELGSGAFAQVFKGINKQTNTDVAIKVISRQK----------------LKKYGEEIINAIGDEVNILQKLS----FLSQ------KDPCPFIVKIF | . .|.|.|..|.|. ..... ..|||.| || .| . . |..| | .|.... .. . .. .|.|.|.. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMY DCFQ--TTNNIYIILEYCNGGNLLDIIK----KCPQGIP------EQQAIKIFYQIVS---------------GINYIAKHD-IVHRDLKPENIFIHDGV .||| ..||||...|||.||.|.|.|| |... |. |.....|..||.. ...|. . |.|||.|||||.. ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---- YKIGDFGFAS-----------------------------------QKNMFYTTLGTYPYMAPEFFKDPS---------YDKLVDIWAVGIMYHEMLFNEL || |||.. | |||.|..||..||||| .. . ||. .|||..|.. .||||... IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP YFMGNSQYEVSQKICNVPYKIVRPNM----------------ISPNSQDVLIK----CIEKDRSVRIT-ADQLINHPLF | |.|.. .... |.. .|.. .| . | ...|| . ||| ..|..||| | PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 7935.AA | ULK | 13-272 | 32 | 3.5e-84 | 286.0 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-329/329 Sequence Identity: 32% (109 aa) YSESNELGSGAFAQVFKGINKQT----NTDVAIKVISRQKLKKYGEE-----IINAIGDEVNILQKLSFLSQKDP------CPFIVKIFDCFQTT--NNI |. ...||.|.|..|.||.||.| | .||.|.|..||... | ... . |. |..|| |.| .| ||| .|.|.|. ||| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKL-----KSPNRHKNHHPNIVKLYDWFETSNHNNI YIILEYCNGGNLLDIIK---KCP------QGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIHDG-------------VYKIGDFGFASQKN-- |||.||||||.| ..|| |.| . ..||.||..|.||..| .. || |.|||.||.|| ||.| |.||.||||| . . YIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDND -----MFYTTL------GTYPYMAPEFFKDP----SYD-KLVDIWAVGIMYHEMLFNELYFMGNSQYEVS-----QK----------ICNVPYKIVRP-- |..|.. || ||||. ... |. . .||| .|....|||... .| .. .. . |.. | .. . NMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN -NMISPNSQDVLIKCIEKDRSVRITADQLINHPLF . |||...| . .....|.. ||. ..|.|||.| DPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | 7935.AA | S_TKc | 13-272 | 34 | 9.5e-84 | 285.45 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-231/231 Sequence Identity: 34% (94 aa) YSESNELGSGAFAQVFKGINKQTNTDVAIKVISRQKLKKYGEEIINAIGDEVNILQKLSFLSQKDPCPFIVKIFDCFQTTNNIYIILEYCNG--GNLLDI | ...|.|||..|.|...| |. ||||.|. . | |..||.| .|.|||..|.||. ...|...|||.| |.|.|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY IKKCPQG-----IPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIHDGVYKIGDFGFASQKNMFYTTLGTYPYMAPEFFKDPSYDK-LVDIWAVGI |||.. . .|| .| ...|||.....|. .| |.|||||||||.. . . ||.|||.| | .| || ||||| . .|.| .|.|..|. IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC MYHEMLFNELYFMGNSQYEVSQKICNVPYKIVRPNMISPNSQDVLIKCIEKDRSVRITADQLIN-------HPLF . ||| . | .... .||. || | . || .|| . |.|| .. . || | ILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 7935.AA | Pkinase | 13-272 | 30 | 1e-74 | 259.31 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-293/293 Sequence Identity: 30% (91 aa) YSESNELGSGAFAQVFKGINKQTNTDVAIKVISRQKLKK-YGEEIINAIGDEVNILQKLSFLSQKDPCPFIVKIFDCFQTTNNIYIILEYCNGG----NL | .|||.|..|.|...| |. ||.|.|.... |. .. ... |. |...|. .|.||...|.|.. ..||...|||.|| | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLN-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDL LDIIK-KCPQGI--PEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIH-DGVY----KIGDFGFASQ----KNMFYTTLGTYPYMAPEFFK-DPSYD |.|. . .. .|.......|||..|..|. .. |.|||||||||.|. .|. ||.|||.| | . ..| ||..||||| . .. |. FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYG KLVDIWAVGIMYHEMLFNELYFMGN------SQYEVSQKICNVPYKIVRPNMIS-------------------PNSQDVLIKCIEKDRSVRITADQLINH . ||.|..|.. .|||. .. | | .|... ..| |.. .|. .| .. .|.. .|..|| . |.||.|. .| PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH PLF | | PWF |
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Kinase | 7935.AA | AGC | 13-272 | 21 | 1.7e-74 | 191.15 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-395/395 Sequence Identity: 21% (87 aa) YSESNELGSGAFAQVFKGINK------QTNTDVAIKVISRQK---LKK--YGEEIINA--------IGDEVNILQKLS------FLSQKDPCPFIVK-IF . .| |.| .|. | .|. |.||.. .. .|| | .... . | |||.|.. . .||||| . FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPI-KS--HHPFIVKILH DCFQTTNN--IYIILEYCN---------GG-NLLDIIKK--CPQGIPEQQAIKIFYQ-------IVSGINYIAK-HDIVHRD-LKPENIFIHD-GVYKIG .||. .. .|...||.. || |. .... . .|..| .. . ||... |. . ..|.||| |||||| . . | |. YSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLT DFGFASQ------------------------------------------------------KNMFYTTLG--TYPYMAPEFFKDPSYDKLVDIWA--VGI |||.. . ... .| | | ||||| . |.| .|.|. .|. DFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGC MYHEMLFNELYFMGNS----------QYEVSQKIC------NVPYKIVRP--------NMISPNSQDVLIKCIEKDRSVRIT----------ADQLINHP . |||. | |.. ..|. |||. | . |. .| .||. .| . |...||.. |.. |... ||| LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP LF | WF |
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Kinase | 7935.AA | CAMK | 18-272 | 21 | 2.5e-74 | 238.72 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 18-272 Range on HMM: 1-425/425 Sequence Identity: 21% (94 aa) ELGSGAFAQVFKGINKQTN------------TDVAIKVISRQKLKKY-----------------------GEEIINAIGDEVNILQKLS----FLSQKDP .||.|.|..|...|.|.|. . ||||.|...|||. .. . |..|..||. .|. TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLD---- CPFIVKIFDCFQ------------TTNN--------IYIIL---EYCNGG----NLLDIIKKCPQG--------------IPEQQAIKIFYQIVSGINYI | |.|... .. | .. .|... ||| || |.| |.. ... ..|..| ..| ||.|...|. HPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYC AKHDIVHRDLKPENIFI-HD-----------------GVYKIGDFGFASQKNM---------------------------FYTTLGTYPYMA-PEFFKD- .|.||||||||||| . .. . || ||||| ... ..| || .||| || .. HSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK -------------PSYDKLVDIWAVGIMYHEMLFNELYFMGN-------------SQYEVSQKICNVPYKIVRPNM--------------ISPN------ | |.. .|.|..|.. || .. | | ..|| .||.. | | . || . GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS --SQDVLIKCIEKDRSVRITADQLINHPLF .| . |. ..| . |.|..| ||| . QECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 7935.AA | Ciliate-B1 | 13-271 | 34 | 7.1e-66 | 225.17 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 13-271 Range on HMM: 1-290/290 Sequence Identity: 34% (100 aa) YSESNELGSGAFAQVFKGI---NKQTNTDVAIKVISRQKLKKYGEEIINAIGD-EVNILQKLSFLSQK-------DPCPFIVKIFDCFQTTNNIYIILEY |. |..|.||. |||.| |.|.. ||.|.|. |.. .... | | .|.|.|.. .||. |. |.| .|. ||| || YQQNNVIGQGAISQVFYGQFCQNQQCQQEVAVKKITKQTQ--DNDKQQNKYYQQELEIIQCLIKKMNNNKISCQSSPCDHICNIYDVIQCQQQYYIIMEY CNGGNLLDIIKKCPQGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIH-----------DGVY--KIGDFG-FASQKN-MFYTTLGTYPYMAPE |..|.|.. | .| | . .. . ||..||.| ||.|.|||||||||.|| ...| ||.||| .|.. |. . || ||||| CEQGDLYNYIYNCHQNFTHDIVLDFCIQIAKGIQYLHKHKICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQEYMMQSCVGTINYMAPE FFK-DPSYDKLVDIWAVGIMYHEMLFNELYFM--GNSQYEVSQKICNVPYKIVRPNMISPNSQDVLI----KCIEKDRSVRITADQLINHPL .. .||| ||||. |. .| . ||..| ||.| ||...| | . . . .. | . .| ..| . |||.||.|. . ILNFNQQYDKKVDIWSFGCIMYEIITNEQLFCSLGNTQQEVANQIRNFQCCDYQCHFQNNIYQEIQQLIQKYCLQPDPENRITIDQIIDRLM |
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Kinase | 7935.AA | CAMKL | 13-272 | 29 | 8.5e-63 | 199.18 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-297/297 Sequence Identity: 29% (92 aa) YSESNELGSGAFAQVFKGIN-KQTNTDVAIKVISRQKLKKYGEEIINAIG----------DEVNILQKLS---FLSQKDPCPFIVKIFDCFQTTNN---- | .|| |.|..| ... . |.. ||||.| ..|... | .| |..|...|. | |.|......| .. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKH-------PNIIKLYEVIETPEHDIET --IYIILEYCNGGN--LLDIIKKCP---QGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIH-DG--VYKIGDFGFASQ--------KNMFYTT ||...||| ||. |.| |.| . . .|| .| ..| ||||..||. .|.|||||.||||| . .| . || ||||. . ... | KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTF LGTYPYMAPEFFKD--PSYD-KLVDIWAVGIMYHEMLFNELYFMGN--------SQYEVSQKICNVPYKIVRPNMISPNSQDVLIKCIEKDRSVRITADQ |..|||||| |.. .|| . ||||. |.. |.. .| | . . . || |.. .. .| .| . | ... . |.|..| CGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ LINHPLF . ||| . IMNHPWM |
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Kinase | 7935.AA | STE | 13-272 | 23 | 2.2e-57 | 196.98 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-359/359 Sequence Identity: 23% (85 aa) YSESNELGSGAFAQVFKGINK------QTNTD---------VAIKVISRQKLKKYGEE-------IINAIGDEVNILQKLSFLSQKDP-CPFIVKIFDCF . ..|.||| .|.|..|. .|. .|||... .. ... | . . .. .||. ...... .. .|.||| ..|. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY QTT-------NNIYIILEYCNGGNLLDIIK---KCPQG----------IPEQQAIKIFYQIVSG-INYIAKHDIVHRDLKPENIFIHDGVYKIGDFGFAS ....|..||..|| | |||| .|... .||.| ..| .||. | .|. .| |.|||.|| ||.. |. |||... FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCG QKN--------------------MFYTTLGTYPYMAPEFFK------DPSYDKLVDIWAVGIMYHEMLFNELYFMGNSQYEVSQKIC------------- | . . .| || .|||| . |. || .||| .|.. ||. . .. . .. | QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC ---NVPYKIVR-----------------PNMISPNSQDVLIKCIEKDRSVRITADQLIN--HPLF . | .. | ||. .| . || .|| . | ||.||.. || . IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | 7935.AA | Ciliate-E2c | 13-272 | 28 | 6.1e-48 | 165.58 | In-house | 1-310 (310) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-310/310 Sequence Identity: 28% (90 aa) YSESNELGSGAFAQVFKG---------INK-QTNTDVAIKVISRQKL--KKYGEEIIN-AIGDEVNILQKLSFLSQKDPCPFIVKIFDCFQTTNNIYIIL ... | |||| ...|.|. ||. | |. ||| . . . . . | .| .| |.|.. .. | |.|. | .||...||.|. IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMN-------HPHIIKFYDAKQTDKHIYLIM EYCNGGNLLDIIKKCPQGIPEQQAIKIFYQIVSGINYIAKH-DIVHRDLKPENIFIHDGVYKIGDFGFA---SQKNMFYTT-----LGTYPYMAPEFFKD ||||||.|.. |.. |. . |.| . | ||.|. .|. | | |||.|||||.||.|. || ||||. | .|. || ||||. . EYCNGGTLEQYIYHKPK-PNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEG PSYDKL--VDIWAVGIMYHEMLFNELYFM------------------GNSQYEVSQKIC---------------NVPYKIVRP--NMISPNSQDVLIKCI .. . ||| |.. .||. .| . .|.. . | | . . . ..||. .. . | . -KNYYTEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKML EKDRSVRITADQLINHPLF ..| . || |...||... QVDEEKRIDWDEIFNHECI |
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Kinase | 7935.AA | TyrKc | 13-272 | 20 | 9.9e-17 | 47.8 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 13-272 Range on HMM: 1-280/280 Sequence Identity: 20% (63 aa) YSESNELGSGAFAQVFKGINKQTNTDVAIKVISRQKLKKYGEEIINAIGDEVNILQKL--SFLSQKDPCPFIVKIFDCFQTT-------NNIYIILEYCN . .||.||| .|.||. | ..||.|.. . . .. .| .|. || . | ||... . . ..|..||. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGH-------HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP GGNLLDIIKKCPQGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIHDGV-YKIGDFGFASQKNMF--------YTT-----LGT--YPY--MAP .|.|.| ..|. .. .. ... .|| .| .|.... ..|||| |. .... ||.||| . | . | |. ||| HGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP EFFKDPSYDKLVDIWAVGIMYHEML-FNELYFMG-----NSQYEVSQKICNVPYKIVRPNM--------ISPNSQDVLIKCIEKDRSVRITADQLINHPL | ... . |.|. |.. |.. . . | | .|| ... | .| .. .. .| . | . | | .. | . ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC F | F |
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Kinase | 7935.AA | Pkinase_Tyr | 93-165 | 35 | 1.6e-12 | 43.03 | Pfam | 80-156 (270) | Show / Hide |
Range on Protein: 93-165 Range on HMM: 80-156/270 Sequence Identity: 35% (27 aa) NNIYIILEYCNGGNLLDIIKKC---PQGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIH-DGVYKIGDFG |.|||..||. .|.||| .| .| .. .. ... .|| .| .| . . ..|||| |. .. ..| ||.||| NQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG |
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Kinase | 7935.AA | Pkinase_Tyr | 13-44 | 36 | 5e-06 | 21.07 | Pfam | 1-36 (270) | Show / Hide |
Range on Protein: 13-44 Range on HMM: 1-36/270 Sequence Identity: 36% (13 aa) YSESNELGSGAFAQVFKGINK----QTNTDVAIKVI . .||.||| .|.||. | .|...||.|.. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML |