Gene 4069 (Tetrahymena)
4069
Sequence
Protein domains of 4069.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 4069.AA | AGC | 141-273 | 33 | 3.3e-91 | 235.36 | In-house | 181-395 (395) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 181-395/395 Sequence Identity: 33% (73 aa) LKPENVLIDQEGYIKLTDFGLSKILQNDN--------------------------------------------------EVATSVAG--TPEYLAPEILS |||||.|.|..|.||||||||.|.. ||. . ... | ||||.||||| LKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL- EKGHGKASDWWT--LGNIIYEMVTGLPPFYDPN----------REKLFGNIL------TQPVKFD----------PRIQGNLKDLLSGLLQKDPNKRLGS .||| |||. || ..|||.||.||||. | ....| .|. ...|||. . . ..|||...||.|||.||||. ---YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGC KY------GALEIINHPWF . || || ||||| GGNDFGDKGAEEIKNHPWF |
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Kinase | 4069.AA | Akt | 141-273 | 53 | 2e-85 | 273.06 | In-house | 127-264 (264) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 127-264/264 Sequence Identity: 53% (74 aa) LKPENVLIDQEGYIKLTDFGLSK-ILQNDNEVATSVAGTPEYLAPEILSEKGHGKASDWWT-LGNIIYEMVTGLPPFYDPNREKLFGNILTQPVKFD--P |||||.|.|..|.|.||||||.| .. |....... |||||||||||. .||.||.|||. || ..||| .|.||||. .....| .|..||||| . LKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKD RIQGNLKDLLSGLLQKDPNKRLGSKYG-ALEIINHPWF .|. . |||.||||.|||.||||.... | || .|||| WISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | 4069.AA | Ciliate-E2 | 41-273 | 25 | 1.8e-77 | 263.7 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 41-273 Range on HMM: 1-365/365 Sequence Identity: 25% (96 aa) FNLLTIIGQGNYA-----KVSLVRK------------------KDDGQIYALKTLKRKHIKHQVQMNHIL----------TERNILKVVDSQYIVRCKYA .... .|||||.. || .|.| |....|||.|..| . |... |..||. |.|||. ... .|...... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--DKKRLFFALEFCQGGELFTLIK----------------------------TKGF-----------------LNENP------LKPENVLIDQEGYI || |.. ... .|.||||.|| .|| ..|| | .. .||||.|. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLTDFGLSKILQNDNE-------------------------------VATSVAGTPEYLAPEILS---------EKGHGKASDWWTLGNIIYEMVTGLPP |..||||||....||. .. ...|||.|.|||||. .||.....|.| || |.|||..| || KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FYDPNREKLFGNILTQPVKFD------------------PRIQGNLKDLLSG----LLQKDPNKRLGSKYGALEIINHPWF | . .|. ....|. . . |||.. .|||||.||.. |. .|.||||| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT---GWEQILNHPWF |
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Kinase | 4069.AA | SGK | 141-273 | 50 | 2e-71 | 219.71 | In-house | 151-283 (283) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 151-283/283 Sequence Identity: 50% (67 aa) LKPENVLIDQEGYIKLTDFGLSKILQNDNEVATSVAGTPEYLAPEILSEKGHGKASDWWTLGNIIYEMVTGLPPFYDPNREKLFGNILTQPVKFDPRIQG |||||.| | .|...||||||.| .|. .. .|||||||||.| ..|... ||| || . ||| .||||||. |.. .. ||. || .. | .. LKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSN NLKDLLSGLLQKDPNKRLGSKYGALEIINHPWF .||. ||||||| ||||.| ...|| |||.| DAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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Kinase | 4069.AA | S_TKc | 41-273 | 33 | 5.7e-70 | 239.69 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 41-273 Range on HMM: 1-231/231 Sequence Identity: 33% (91 aa) FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQG--GELFTLIKTKGF--- . .| .||.| ..|| ..|.|..|.|.|.| .| .||. |..||| . .||.....||| ..|.. .|.| | |.||..|| .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LNENP------------------------LKPENVLIDQEGYIKLTDFGLSKILQNDNEVATSVAGTPEYLAPEILSEKGHGK-ASDWWTLGNIIYE ..| |||||.|.|. ||..||||...| |.. |||.|.|||.| |.|| ..||| .| |.|| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE MVTGLPPFYDPNREKLFGNILTQPVKFDPRIQGNLKDLLSGLLQKDPNKRLGSKYGALE----IINHPWF |..| |||. . ...| .|. .||.....|||||.||.. ||. | .|||| MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA--EALQDEWDIKCHPWF |
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Kinase | 4069.AA | AktR | 141-273 | 49 | 9.3e-68 | 231.42 | In-house | 128-268 (268) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 128-268/268 Sequence Identity: 49% (70 aa) LKPENVLIDQEGYIKLTDFGLSK--ILQNDNEVATSVAGTPEYLAPEILSE-KGHGKASDWWTLGNIIYEMVTGLPPFYDPNREKLFGNILTQP-VKFDP ||||| |.|..|..|.||||||| . ..|.|.|. |||||.|||.. . |||.|..|||..| |||||||.||||. |.. .| .|.... .||.. LKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPY RIQG--NLKDLLS-GLLQKDPNKRLG-SKYGALEIINHPWF .. ..|||. .||.|.|||||| .. |. || .|||| PSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | 4069.AA | PKA | 141-273 | 46 | 4.7e-60 | 205.84 | In-house | 127-263 (263) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 127-263/263 Sequence Identity: 46% (65 aa) LKPENVLIDQEGYIKLTDFGLSKILQNDNEVATSVAGTPEYLAPEILSEK-GHGKASDWWTLGNIIYEMVTGLPPFYDP--NREKLFGNILTQPVKFDPR ||||| |||..|.||.|||| .| ... . .. ||||||||||.. | ||||. |||.|| .||||..| ||||| . ... |. .||.. LKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRH IQGNL---KDLLSGLLQKDPNKRLGSKY-GALEIINHPWF . .. |||.. |||.|..||.|.. |. | ||.|| FDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | 4069.AA | Ciliate-E2-Unclassified | 141-273 | 30 | 1.6e-57 | 197.42 | In-house | 170-352 (352) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 170-352/352 Sequence Identity: 30% (56 aa) LKPENVLIDQEG---YIKLTDFGLSKILQND---------------NEVATSVAGTPEYL----APEILSEKGHG----KASDWWTLGNIIYEMVTGLPP .||||.|.|..| |||..|||.|| .|.. .. .....|||.|. |||.| ..... ...|.|.|| |.|||..| .| IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP FYDPNREK----------------LFGNILTQPVKFDP--------RIQGNLKDLLSGLLQKDPNKRLGSKYGALEIINHPWF |||.|.|. |. ||. ....|.. ... . ||... ||||...|........ .|.||||| FYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 4069.AA | RSK-Unclassified | 141-273 | 41 | 3.9e-55 | 171.39 | In-house | 127-283 (283) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 127-283/283 Sequence Identity: 41% (65 aa) LKPENVLIDQEGYIKLTDFGLSKIL---------------------QNDNEVATSVAGTPEYLAPEILSEKGHGKASDWWTLGNIIYEMVTGLPPFYDPN |||.|.. .||| ..||||.||. . . | || ||||||.. ||.|| |||||| ..||| |.||.| | LKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNN REKLFGNILTQPVKFD--PRIQGNLKDLLSGLLQKDPNKRLGSKYG-ALEIINHPWF .. .| ||....||| | | .||. |||. | ||||.| | | .| || | KNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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Kinase | 4069.AA | RSK | 141-273 | 42 | 2.7e-53 | 183.37 | In-house | 130-278 (278) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 130-278/278 Sequence Identity: 42% (63 aa) LKPENVLIDQ---EGYIKLTDFGLSKILQND-NEVATSVAGTPEYLAPEILS----EKGHGKASDWWTLGNIIYEMVTGLPPFYD---PNREKLFGNILT |||||.| |. || |||||||..|.. .| |. . . .| ||.|||.| ..||.|| |||.|| ..||| || |||. ||.... .|.. LKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQK QP--VKFD--PRIQGNLKDLLSGLLQKDPNKRLGS-KYGALEIINHPWF .... . . . |||....|..||.||||. . .| || .|||| GKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 4069.AA | Pkinase | 141-273 | 33 | 1.9e-48 | 172.09 | Pfam | 134-293 (293) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 134-293/293 Sequence Identity: 33% (55 aa) LKPENVLIDQEGYI----KLTDFGLSKIL-QNDNEVATSVAGTPEYLAPEILS-EKGHGKASDWWTLGNIIYEMVTGLPPFYDP------NREKLFGNIL |||||.|||..|.| |..||||.| . |. .|...|||.|.|||.. ...|...|.| .| |.|||..| |||.. . ... .|. LKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIM TQPVKFDPRIQ---------------------GNLKDLLSGLLQKDPNKRLGSKYGALEIINHPWF |..|| ..||.....|.|||.||.. | .| .|||| GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF |
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Kinase | 4069.AA | AGC | 41-139 | 31 | 4.7e-48 | 121.19 | In-house | 1-146 (395) | Show / Hide |
Range on Protein: 41-139 Range on HMM: 1-146/395 Sequence Identity: 31% (46 aa) FNLLTIIGQGNYAKVSLVRKK------DDGQIYALKTLKRKH-IKHQV--QMNHILTE------------RNILKVVD----------SQYIVR-CKYAF |..|..||.| . || ||||| | |..||.| || || |. .. |..|| ||||. .. ...||. .|.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDKKR--LFFALEFCQ---------GG-ELFTLIK---TKGFLNEN |||.. |.| .|... || |||. .. .| ..|. QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEE |
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Kinase | 4069.AA | Akt | 41-139 | 40 | 4.9e-45 | 141.87 | In-house | 1-100 (264) | Show / Hide |
Range on Protein: 41-139 Range on HMM: 1-100/264 Sequence Identity: 40% (40 aa) FNLLTIIGQGNYAKVSLVRKKDDGQIY-ALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQGGELFTLIKTKGFLNEN |..| ..|.| ..|| ||.|||....| |.| || ..| . | |..||||||. .....|| .|.||....|.| ...|.|||||.... |.. .|. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED |
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Kinase | 4069.AA | RSK | 141-273 | 38 | 9.1e-43 | 148.4 | In-house | 127-271 (271) | Show / Hide |
Range on Protein: 141-273 Range on HMM: 127-271/271 Sequence Identity: 38% (56 aa) LKPENVLIDQE----GYIKLTDFGLSKILQNDNEVATSVAGTPEYLAPEILSEKGHGKASDWWTLGNIIYEMVTGLPPFYDPNREKLFGNILTQPVKF-- |||||.|.| | | ||..|||..| | .|. . . .| .|.|||.|. .||..|.||| .| . ||| || .||. .|. .. .|. ... LKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFS -----DPRIQGNLKDLLSGLLQKDPNKRLGS-KYGALEIINHPWF | ||||...| ||..|||. |. .| .|||| MTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | 4069.AA | AktR | 41-139 | 42 | 1.3e-37 | 131.24 | In-house | 1-101 (268) | Show / Hide |
Range on Protein: 41-139 Range on HMM: 1-101/268 Sequence Identity: 42% (43 aa) FNLLTIIGQGNYAKVSLVRKK-DDGQIYALKTLKRKHIKHQVQMNHILTERNILK-VVDSQYIVRCKYAFQDKKRLFFALEFCQGGELFTLIKTKGFLNE | .. ..|.|...|| ||.|| |....||.| .| |.|. . || |..|||||.. .. ||. .|.||.|. |||..|.|.|||||. .|.|....| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE N . E |
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Kinase | 4069.AA | SGK | 41-127 | 32 | 5.5e-32 | 95.7 | In-house | 1-113 (283) | Show / Hide |
Range on Protein: 41-127 Range on HMM: 1-113/283 Sequence Identity: 32% (37 aa) FNLLTIIGQGNYAKVSLVRKKDD------------------GQIYALKTLKRKHIK-------HQVQMNHILTER-NILKVVDSQYIVRCKYAFQDKKRL | .|..||.|.. || .|..||| ...||.| |...|| . .||..|| .||| . . || .|||| |. | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL FFALEFCQGGELF .| ... .|||.| YFVMDYVNGGEMF |
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Kinase | 4069.AA | PKA | 41-138 | 32 | 4.5e-29 | 102.9 | In-house | 1-99 (263) | Show / Hide |
Range on Protein: 41-138 Range on HMM: 1-99/263 Sequence Identity: 32% (32 aa) FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVR-CKYAFQDKKRLFFALEFCQGGELFTLIKTKGFLNE |.... .|.| ...| |.|.|..|..||.|.||. |.. | |...|.|||. ... .||. .. ||| . |.. .|...|||.|. . .| ... FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN |
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Kinase | 4069.AA | Ciliate-E2-Unclassified | 41-139 | 23 | 1.3e-27 | 92.86 | In-house | 1-138 (352) | Show / Hide |
Range on Protein: 41-139 Range on HMM: 1-138/352 Sequence Identity: 23% (32 aa) FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNH---------ILTERN-------------ILKVVDSQYIVRCKYAFQDKKRLFFAL .... .||||...|| ....|...|.||.|..| ..|..| |... .. ... ||. .. .||.. |.||||. ... . YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM EFCQGGELFTLIKTKGF-----------------LNEN |.|.||.|. || ... . |. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQ |
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Kinase | 4069.AA | Pkinase | 41-139 | 28 | 1.6e-27 | 98.43 | Pfam | 1-108 (293) | Show / Hide |
Range on Protein: 41-139 Range on HMM: 1-108/293 Sequence Identity: 28% (31 aa) FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHIL-TERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQGG----ELFTLIK--TK . .. .||.|....| . ..|..|.|.|.|..|..|.|......|.. .| |.| ... .|||....|.||... . .|.|.|| .||..|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GFL--NEN | . |. GCFYFSEW |
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Kinase | 4069.AA | RSK-Unclassified | 41-127 | 37 | 9.5e-27 | 80.62 | In-house | 1-87 (283) | Show / Hide |
Range on Protein: 41-127 Range on HMM: 1-87/283 Sequence Identity: 37% (33 aa) FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQGGELF | |||| || |||||| ||||.| |... . . ..||.||. . . .||. ..|| . .|. .|.| ||..| FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFF |
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Kinase | 4069.AA | RSK | 41-139 | 29 | 1.3e-25 | 88.54 | In-house | 1-101 (271) | Show / Hide |
Range on Protein: 41-139 Range on HMM: 1-101/271 Sequence Identity: 29% (30 aa) FNLLTIIGQGNYAKVSLVRKK---DDGQIYALKTLKRKHIKHQVQMNHILTERNILKVVDSQYIVRCKYAFQDKKRLFFALEFCQGGELFTLIKTKGFLN ..|. |||| . || ...|. | .| || | .| . .. . .||.|| .....||. .|.||| . .. ..|..||.||. . .... YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS EN |. ER |
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Kinase | 4069.AA | RSK | 44-139 | 42 | 1.3e-24 | 87.09 | In-house | 1-104 (278) | Show / Hide |
Range on Protein: 44-139 Range on HMM: 1-104/278 Sequence Identity: 42% (44 aa) LTIIGQGNYAKVSLVRKK---DDGQIYALKTLKR-KHIKHQVQMNHILTERNILKVVD-SQYIVRCKYAFQDKKRLFFALEFCQGGELFTLIKTKGF--- | ||| | ||.|.||. | ||||| | ||. | ...|. | .||||||. . .. ||. .||||... |. .|.| |||||| ...... LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LNEN . |. FSED |
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Kinase | 4069.AA | S_TK_X | 274-333 | 26 | 1.8e-13 | 51.96 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 274-333 Range on HMM: 1-79/79 Sequence Identity: 26% (21 aa) SDLNWESLRL--RKIIPPFKPKVD----NEIDVSYFSPDFLE--MEFSPNDE--PGSLSQPS---------IQGFSISN ....|. |. ..| ||||||. ...|.|.| |.| | .| |. .| |. ||. .. RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | 4069.AA | TyrKc | 41-267 | 16 | 4.9e-10 | -60.42 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 41-267 Range on HMM: 1-280/280 Sequence Identity: 16% (47 aa) FNLLTIIGQGNYAKVSLVRKKDDGQIYALKTLKRKHIKHQVQMNHILTERNILKVV--DSQYIVRCKYAFQDK-------KRLFFALEFCQGGELFTLIK |. ..| |.. .| . . | . | |.|| . . .. | .|.. . . . |||. . .. . |. .|.. .| | .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR TKG--------------------FLNENP-----LKPENVLIDQEGYIKLTDFGLSKILQND-----NEVATSVAG--TPE------YLAPEILSEKGHG .. .| ... | |.|.. .. .| .|||||. . .| .. .... .||| . .. KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT KASDWWTLGNIIYEMVT-GLPPFYD-----PNREKLF-----GNILTQPVK-----FDPRIQGNLKDLLSGLLQKDPNKRLGSKYGALEI .|| | | ..|. | | .| .. . . .. |. . || | .. . .. . . ||..| . .. TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 4069.AA | Pkinase_Tyr | 145-170 | 34 | 0.001165 | 13.02 | Pfam | 141-166 (270) | Show / Hide |
Range on Protein: 145-170 Range on HMM: 141-166/270 Sequence Identity: 34% (9 aa) NVLIDQEGYIKLTDFGLSKILQNDNE |.|.. .. .| .||||.. ..|| . NCLVTENNVVKICDFGLARDIYNDDY |
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Kinase | 4069.AA | Pkinase_Tyr | 41-126 | 18 | 0.072677 | 6.94 | Pfam | 1-94 (270) | Show / Hide |
Range on Protein: 41-126 Range on HMM: 1-94/270 Sequence Identity: 18% (18 aa) FNLLTIIGQGNYAKVSLVRKK----DDGQIYALKTLKRKHIKHQVQ--MNHILTERNILKVV-DSQYIVRCKYAFQ-DKKR--LFFALEFCQGGEL .. .|.|.. .| . . | .... | |.| |. .. | . . | .|.| . . |||. . ... .. .|....| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL |