Gene 3995 (Tetrahymena)
3995
Sequence
Protein domains of 3995.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 3995.AA | AGC | 19-277 | 27 | 4.1e-123 | 319.77 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-395/395 Sequence Identity: 27% (108 aa) YKFFELVGTGGFSKVWKVQKDG-----QT-SFRALKQMVKYR---IMSKNSVEAILNE------------RQILENLD----------HPFIIN-MYSAF ..| ..|.|.|.||. |.| . .| . |.| . | . |. || || ...| |.|||... ||||.. ....| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDKYN--LYLIMDYLP---------GG-DLRYHIK---QTKIFSEQNAKFMMAC-------TLVALEYVHS-KNIIHRD-IKPENLVFDSQGYLRLTDFG ||| . ||..|.|.| || .| .|.. . ..|.|. |.|..|. .. |||| || ..||||| .||||...|..|...||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG ISRYTKTDN----------------------------------------------------SNETSG--TPGYLAPETLMRLNHGKESDFFG--LGVVLF . ..|. . | || |.||| | .||. | . ||.... LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY ELIKGYRPYNVRS----------RKEMRDKIF------EKEIQLDPSHDH-----GEVSANCIDLINKLIKIKPFKRIGCN-------GIEEIFKHPWF |.. || |.. . ..|| .|| ........ | ..| .. |||.||.. | ||.||. |.||| .|||| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 3995.AA | Ciliate-E2-Unclassified | 19-277 | 30 | 4.4e-107 | 362.04 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-352/352 Sequence Identity: 30% (109 aa) YKFFELVGTGGFSKVWKVQKDGQTSFRALKQMVKYRIMSKNSVEA---------ILNERQ-------------ILENLDHPFIINMYSAFQDKYNLYLIM ||. . |.|||.||.|.|.. | . |.|.| |..| ...... ..|... || |..||||..|. .|||| |.|..| YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM DYLPGGDLRYHIKQT-----------------KIFSEQNAK-----FMMACTLVALEYVHSKN-IIHRDIKPENLVFDSQG---YLRLTDFGISR----- .|..||||...||. |||.||.|| |..|. |..||| |.|| ||||||||||..||..| |....|||||. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN ------------YTKTDNSNETSGTPGYL----APETLMRLNHG----KESDFFGLGVVLFELIKGYRPYNVRSRKE----------------MRDKIFE ..| .... ..|||.|. ||| |.. |.. ...|...|||.|.|.. ||.|.. ..... ....|.. NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ KEIQLDPSH---DHGEVSANCIDLINKLIKIKPFKRIGCN-GIEEIFKHPWF |.|| ... .. .| ...|.||.|.. .. |... . ..|.|..|||| KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 3995.AA | Ciliate-E2 | 19-277 | 29 | 9e-99 | 334.44 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-365/365 Sequence Identity: 29% (113 aa) YKFFELVGTGGFS-----KVWKVQK-----------------DGQT-SFRALKQMVKYRIMSKNSVEAIL----------NERQILENLDHPFIINMYSA ||| .. |.|.|. ||||||| .... .. |.|.| |. | ...... |. ||..|||.|.||.||.|| . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--DKYNLYLIMDYLPGGDLRYHIK-------------------QTKIFSEQNAK-------FMMACTLVALEYVHSKN-IIHRDIKPENLVFDSQGYL || |. |.||.|.|. ||||...|| . | ...| .. |..|| ..|||| |||| ||||||||||..| . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I RLTDFGISRYTKTDNSNET---------------------------------SGTPGYLAPETLMRLN---------HGKESDFFGLGVVLFELIKGYRP ..|||.|.. ..|| |.| |||||.||| |.. . .....|.. |||.|.|.. |..| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP YNVRSRKEMRDKIFEKEIQLDPSH-------------DHGEVSANCIDLINK----LIKIKPFKRIGCNGIEEIFKHPWF . ..| ...|.... . .. ..| .|.|||.| ... .| |||. |.|.|..|||| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF |
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Kinase | 3995.AA | S_TKc | 19-277 | 32 | 5.1e-84 | 286.34 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-231/231 Sequence Identity: 32% (89 aa) YKFFELVGTGGFSKVWKVQKDGQTSFRALKQMVKYRIMSKNSVEAILNERQILENLDHPFIINMYSAFQDKYNLYLIMDYLPG--GDLRYHIKQTKI--- |.. ...| |.|.||.|... . |.|.. | |..|.|||.. .||.|...| .||| .||..|.|..| |||. .||. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FSEQNAKFMMACTLVALEYVHSKNIIHRDIKPENLVFDSQGYLRLTDFGISRYTKTDNSNETSGTPGYLAPETLMRLNHGK-ESDFFGLGVVLFELI |.| |.|.|. .. |||| ||..|||||.||||. .|. . ..|||..| . ||| |.||| | .|| ..| .|..|.|.. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML KGYRPYNVRSRKEMRDKIFEKEIQLDPSHDHGEVSANCIDLINKLIKIKPFKRIGCNGIEE----IFKHPWF || |. ..| .|| | ..|.|.|. . | ||... . . | .|||| CGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 3995.AA | SGK | 19-277 | 35 | 9e-81 | 249.08 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-283/283 Sequence Identity: 35% (104 aa) YKFFELVGTGGFSKVWKVQKDGQ------------------TSFRALKQMVKYRIM-------SKNSVEAILNER-QILENLDHPFIINMYSAFQDKYNL .| ..| |.| || |.. . | |.| | | |... |. || || |. ||||.| ||| | | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLIMDYLPGGDLRYHIKQTKIFSEQNAKFMMACTLVALEYVHSKNIIHRDIKPENLVFDSQGYLRLTDFGISRYTKTDNSNETS---GTPGYLAPETLMR |. |||. ||.. ||.. |.|.| |.| .| |||| ||..||.|| ||||.. |.||...||||| . . ...|. ||| ||||| | YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK-EGIKTNDTTFTFCGTPEYLAPEVLRK LNHGKESDFFGLGVVLFELIKGYRPYNVRSRKEMRDKIFEKEIQLDPSHDHGEVSANCIDLINKLIKIKPFKRIGCN-GIEEIFKHPWF |... | . || ||.|.. | |. | ...| |.| ...|. |. .|. . |||. | . | || | . . .|| .||.| QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQ-----MSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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Kinase | 3995.AA | AktR | 19-277 | 38 | 2.6e-78 | 266.48 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-268/268 Sequence Identity: 38% (104 aa) YKFFELVGTGGFSKVWKVQKD-GQTSFRALKQMVKYRIMSKNSVEAILNERQILE-NLDHPFIINMYSAFQDKYNLYLIMDYLPGGDLRYHIKQTKIFSE ... .. | |.|.|| ||| . |.| | | .| .....||.|.| .||||.... .||.|..|..||.| |||.| .|.|. | ||| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE QNAKFMMACTLVALEYVHSK-NIIHRDIKPENLVFDSQGYLRLTDFGISR--YTKTDNSNETS--GTPGYLAPETLMR-LNHGKESDFFGLGVVLFELIK . |.| .| | |||| |.. ||| ||.||||.. |. |....|||| |. . .. ..| ||| |.|||.... |.| .|. .|....|.. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GYRPYNVRSRKEMRDKIFEKEIQLDPSHDHGEVSANCIDLIN-KLIKIKPFKRIG--CNGIEEIFKHPWF |. | .. ....| .|| .|. |. . .. ..| .| |||. || . | ||.| |||.||| .|||| GCPPFYHKNQNQMFQKIKIKQ-QNKF-PYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | 3995.AA | RSK | 23-277 | 34 | 1.1e-75 | 257.71 | In-house | 3-278 (278) | Show / Hide |
Range on Protein: 23-277 Range on HMM: 3-278/278 Sequence Identity: 34% (97 aa) EL--VGTGGFSKVWKV-QKDGQTSFRALKQMVKYRIMSKNS-VEAILNERQILENLD-HPFIINMYSAFQDKYNLYLIMDYLPGGDLRYHIKQTKI---F .| | | .. . |. ..| .. . | |. | |. .. .. . ||.||| ||||.. . |||.. |||||.|..||.| .|... |. | VLGQGGYGKVFLCRKCTHHDTGQIY-AMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCF SEQNAKFMMACTLVALEYVHSKNIIHRDIKPENLVFDS---QGYLRLTDFGISRYTKTDNSNETS---GTPGYLAPETLM---RLN-HGKESDFFGLGVV || |.| || .|.|. |.. |||||.|||| ..|. .| ..||||| ..... |... | .| |.||| |. . . |.| | . |||. SEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVL LFELIKGYRPYNV---RSRKEMRDKIFEKEIQLDPSHDHGEVSANCIDLINKLIKIKPFKRIGCN--GIEEIFKHPWF ..|. |..|. .||| ..| .... |. ... ..|... |||.|. . | ||.||. ..||| .|||| MYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQ-YLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 3995.AA | Pkinase | 19-277 | 28 | 1.5e-75 | 262.06 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-293/293 Sequence Identity: 28% (84 aa) YKFFELVGTGGFSKVWKVQKDGQTSFRALKQMVKYRIMSKNSVEAIL-NERQILENLDHPFIINMYSAFQDKYNLYLIMDYLPGG----DLRYHIK--QT |.. . .| |.|..|.| .. | |.|.. | .. |. ..... .| ||. .|.||.|. .| .|.|| ..|..|.|..|| || .|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KIF--SEQNAKFMMACTLVALEYVHSKNIIHRDIKPENLVFDSQGYL----RLTDFGISR---YTKTDNSNETSGTPGYLAPETLM-RLNHGKESDFFGL . | ||. .||.| .| .||| ||..|||||.||||. .|..|.. ...|||... | . . |||.|.||| .. . .|...| ... GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVVLFELIKGYRPYNVRS----RKEMRDKIFEKEIQLDPSHDHGEVS--------------------ANCIDLINKLIKIKPFKRIGCNGIEEIFKHPWF |..|.|.. |. |. . . ...... . ... | . . .|.|.|..... .| ||.. .|.|..|||| GCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF |
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Kinase | 3995.AA | Akt | 19-277 | 39 | 8.7e-69 | 218.99 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-264/264 Sequence Identity: 39% (105 aa) YKFFELVGTGGFSKVWKVQKDG-QTSFRALKQMVKYRIMSKNSVEAILNERQILENLDHPFIINMYSAFQDKYNLYLIMDYLPGGDLRYHIKQTKIFSEQ | .. | | | || |.| | . |.| | .| || || .. || ||.. .||||.|.. .||.. .||..||| .||.| ||... ..|||. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED NAKFMMACTLVALEYVHSKNIIHRD-IKPENLVFDSQGYLRLTDFGISRYT-KTDNSNETS--GTPGYLAPETLMRLNHGKESDFFG-LGVVLFELIKGY |.| | |.|. |||||| || ||||.. |..|...||||| .. ..|. .. ||| ||||| | |.| .|. | ||.|..|.. | RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR RPYNVRSRKEMRDKIFEKEIQLDPSHDHGEVSANCIDLINKLIKIKPFKRIG--CNGIEEIFKHPWF |. . ...| .||...... . .| .| |||..| . | || | |...|| |||| PPFYNQDHHQMFKKIKNQPVKFPDK---DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | 3995.AA | RSK-Unclassified | 19-277 | 32 | 5.1e-66 | 206.17 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-283/283 Sequence Identity: 32% (94 aa) YKFFELVGTGGFSKVWKVQKDGQTSFRALKQMVKYRIMSKNSVEAILNERQILENLDHPFIINMYSAFQDKYNLYLIMDYLPGGDLRYHIK--QTKIFSE . |.| | | ||. |.| . |.| . | ... .| . .. |. |. .||||. .| .|| . |||.|.| .|||. | .| |.| FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE QNAKFMMACTLVALEYVHSKNIIHRDIKPENLVFDSQGYLRLTDFGISRYT--------K------------TDNSNETS---GTPGYLAPETLMRLNHG ..| .. . .|||| | . .| || ||.| | . | .||||. | | | . | || ||||| . | |. DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT KESDFFGLGVVLFELIKGYRPYNVRSRKEMRDKIFEKEIQLDPSHDHGEVSANCIDLINKLIKIKPFKRIGC-NG-IEEIFKHPWF | | . ||.|..|. | || . |. | ..... | . ..| || ||| || . | || || | ..| .|| | KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKF-P--HDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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Kinase | 3995.AA | PKA | 19-277 | 36 | 3.2e-62 | 213.04 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 19-277 Range on HMM: 1-263/263 Sequence Identity: 36% (98 aa) YKFFELVGTGGFSKVWKVQKDGQTSFRALKQMVKYRIMSKNSVEAILNERQILENLDHPFIIN-MYSAFQDKYNLYLIMDYLPGGDLRYHIKQTKIFSEQ .... ..||| | .| ... . . . |.|.. | .| . || ..||..|| |..||||.. ||. ||| .||..|.| |||.. ... . ||.. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP NAKFMMA-CTLVALEYVHSKNIIHRDIKPENLVFDSQGYLRLTDFGISRYTKTDNSNETS---GTPGYLAPETLMRL-NHGKESDFFGLGVVLFELIKGY ||| | |||| ||.|||.|| ||||. |..|.. .|||| . .... .|. ||| ||||| . . ||| | ||.. .|. || HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD----RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY RPYNVR--SRKEMRDKIFEKEIQLDPSHDHGEVSANCI-DLINKLIKIKPFKRIGC--NGIEEIFKHPWF | . . .. .|| . .|. |.|.. . | . |||.||. . ||.|. ||.. | .|.|| PPFYDHNRDPMQIYEKICNGKIKF-PRHFDSDA--NYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | 3995.AA | NDR | 19-162 | 39 | 8.3e-51 | 154.58 | In-house | 1-149 (350) | Show / Hide |
Range on Protein: 19-162 Range on HMM: 1-149/350 Sequence Identity: 39% (59 aa) YKFFELVGTGGFSKVWKVQKDGQTSFRALKQMVKYRIMSKNSVEAILNERQILENLD--HPFIINMYSAFQDKYNLYLIMDYLPGGDLRY---HIKQTKI ... ...| |.| .|| |.| . . |.| | | .| || | ...||.|. | .|.. .| .|||| .|||.|.|.||||.. .....| FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI FSEQNAKFMMACTLVALEYVHSKNIIHRDIKPENLVFDSQGYLRLTDFG |.|. |.| .| . .|.|.||. ..|||||||.|.. |..| . ||||| FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG |
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Kinase | 3995.AA | NDR | 177-277 | 29 | 1.8e-21 | 62.38 | In-house | 243-350 (350) | Show / Hide |
Range on Protein: 177-277 Range on HMM: 243-350/350 Sequence Identity: 29% (32 aa) GTPGYLAPETLMR-LNHGKESDFFGLGVVLFELIKGYRPYNVRSRKEMRDKIFEKEIQL--DPSHDH--GEVSANCIDLINKLIKIKPFKRIGCNG--IE ||| |.||| ... ..... |. ||....|.. || | . . .| ..|| .... .. |. ..| . ||| .|. | .|.| .| .. GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVD EIFKHPWF || .||.| EIKSHPFF |
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Kinase | 3995.AA | TyrKc | 19-272 | 20 | 1.9e-13 | -5.28 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 19-272 Range on HMM: 1-280/280 Sequence Identity: 20% (60 aa) YKFFELVGTGGFSKVWKVQKDGQTSFR-ALKQMVKYRIMSKNSVEAILNERQILENL--DHPFIINMYSAFQDK-------YNLYLIMDYLPGGDLRYHI .. . | | | .|.| . . | | . .. .|....| .|. .| .|| |...| . .. |...| | |.|||. .. ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL KQTKI-FSEQNAKFMMACTLVALEYVHSKNIIHRDIKPENLVFDSQGYLRLTDFGISRYTKTD-----NSNETS-----GTPG-----YLAPETLMRLNH . .. .. . .. || ||||.||||. | .... . .||| ||. . | .. . |. . .|||... RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF GKESDFFGLGVVLFELI-KGYRPYNV-----RSRKEMRDKIFEKEIQLDPSHDHGE-----VSANCIDLINKLIKIKPFKRIGCNGIEEIF .|| . ||...|. | || | .|.. .. . . | .| . .. ... . . .| .| . | |.| TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 3995.AA | Pkinase_Tyr | 62-105 | 31 | 0.000924 | 13.36 | Pfam | 48-95 (270) | Show / Hide |
Range on Protein: 62-105 Range on HMM: 48-95/270 Sequence Identity: 31% (15 aa) EAILNERQILENL-DHPFIINMYSAFQ-DKYN--LYLIMDYLPGGDLR |. ..| .|. .| .|| |...| . .. .|..| | |.|||. EDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL |
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Kinase | 3995.AA | Pkinase_Tyr | 129-182 | 29 | 0.471385 | 4.19 | Pfam | 123-176 (270) | Show / Hide |
Range on Protein: 129-182 Range on HMM: 123-176/270 Sequence Identity: 29% (16 aa) ALEYVHSKNIIHRDIKPENLVFDSQGYLRLTDFGISRYTKTDNSNE-TSGTPGYL ..|| .|||.||||. | .... . .||| .|. .. .. .... | | GMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKL |