Gene 3710 (Tetrahymena)
3710
Sequence
Protein domains of 3710.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 3710.AA | CAMK | 1-63 | 22 | 1.9e-23 | 71.78 | In-house | 324-425 (425) | Show / Hide |
Range on Protein: 1-63 Range on HMM: 324-425/425 Sequence Identity: 22% (23 aa) MFALISGELPFYDMK-------------------SIQEGKFAFDAAS------------WKIVSKD--------ARELIEKMLVVNTEKRITLPEAMNHS .... .|..|||. . |..||. |. |. .|.. .. || |||.|. |||.|. ...|| LYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHP WF |. WM |
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Kinase | 3710.AA | CDPK | 14-63 | 36 | 3.8e-21 | 61.79 | In-house | 222-271 (271) | Show / Hide |
Range on Protein: 14-63 Range on HMM: 222-271/271 Sequence Identity: 36% (18 aa) MKSIQEGKFAFDAASWKIVSKDARELIEKMLVVNTEKRITLPEAMNHSWF |.....||. |. |...|..|. ||.|||... .||.. .|..| || MEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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Kinase | 3710.AA | Ciliate-E2a | 1-63 | 31 | 1.2e-20 | 57.56 | In-house | 206-275 (275) | Show / Hide |
Range on Protein: 1-63 Range on HMM: 206-275/275 Sequence Identity: 31% (22 aa) MFALISGELPFYD------MKSIQEGKFAFDAAS-WKIVSKDARELIEKMLVVNTEKRITLPEAMNHSWF .. |..|..||. ... . |. |. |. .||.. |. |||... .|||| .| || || FYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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Kinase | 3710.AA | Ciliate-E2 | 1-63 | 29 | 1.4e-20 | 67.31 | In-house | 286-365 (365) | Show / Hide |
Range on Protein: 1-63 Range on HMM: 286-365/365 Sequence Identity: 29% (24 aa) MFALISGELPFYDMKSIQEGKFAFDAA--------------SWKIVSKDARELIEK----MLVVNTEKRIT-LPEAMNHSWF .. ...|..|| .. |...|. |. . ||| .|... || | ||... ||||| ...|| || LYEMLFGKPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 3710.AA | RAD53 | 15-63 | 42 | 3.3e-20 | 56.42 | In-house | 256-305 (305) | Show / Hide |
Range on Protein: 15-63 Range on HMM: 256-305/305 Sequence Identity: 42% (21 aa) KSIQE-GKFAFDAASWKIVSKDARELIEKMLVVNTEKRITLPEAMNHSWF ..| ||..|. .|. .| |. || .||.|. |||.| ||.||.|. EQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEALNHPWM |
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Kinase | 3710.AA | Ciliate-E2-Unclassified | 1-63 | 24 | 2.1e-18 | 60.44 | In-house | 260-352 (352) | Show / Hide |
Range on Protein: 1-63 Range on HMM: 260-352/352 Sequence Identity: 24% (23 aa) MFALISGELPFY----------------------DMKSIQEGKFAFDAASW----KIVSKDARELIE----KMLVVNTEKRITLPEAMNHSWF ..... |..||| . |..... |. ..| |..|. | ..|. |||..| .||||.....|| || LYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 3710.AA | CAMKL | 1-63 | 35 | 3.3e-18 | 54.57 | In-house | 226-297 (297) | Show / Hide |
Range on Protein: 1-63 Range on HMM: 226-297/297 Sequence Identity: 35% (26 aa) MFALISGELPFYD-----------MKSIQEGKFAFDAASWKIVSKDARELIEKMLVVNTEKRITLPEAMNHSWF ..|.. |.||| | . .. . . |. || |.| || |||.|| |||.|. . ||| |. LYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | 3710.AA | CASK | 2-63 | 35 | 9.1e-17 | 50.63 | In-house | 264-330 (330) | Show / Hide |
Range on Protein: 2-63 Range on HMM: 264-330/330 Sequence Identity: 35% (24 aa) FALISGELPFYDMKS-----IQEGKFAFDAASWKIVSKDARELIEKMLVVNTEKRITLPEAMNHSWF | | || |||. |. | |. .|. |. .| |..|. .|| . .||. ||.|| | FILLSGCLPFFGTKDRLFEMIMKGRYDMDPRYWPHISESAKDLVRRMLMADPHHRISIYEALNHPWI |
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Kinase | 3710.AA | DCAMKL | 15-63 | 40 | 1.9e-16 | 47.13 | In-house | 231-279 (279) | Show / Hide |
Range on Protein: 15-63 Range on HMM: 231-279/279 Sequence Identity: 40% (20 aa) KSIQEGKFAFDAASWKIVSKDARELIEKMLVVNTEKRITLPEAMNHSWF . |..||| |.. .|. .| |..|| .||.|. ||| | . | |.| DQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV |
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Kinase | 3710.AA | RSK | 1-63 | 32 | 1.6e-14 | 49.85 | In-house | 202-278 (278) | Show / Hide |
Range on Protein: 1-63 Range on HMM: 202-278/278 Sequence Identity: 32% (25 aa) MFALISGELPFYD---------MKSIQEGKFAFDAASWKIVSKDARELIEKMLVVNTEKRIT-----LPEAMNHSWF |. . .| .||. || ||.||| .. |. .|..|..|| ||| .. .||.. . | .|.|| MYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 3710.AA | Pkinase | 1-63 | 17 | 7.7e-11 | 39.41 | Pfam | 202-293 (293) | Show / Hide |
Range on Protein: 1-63 Range on HMM: 202-293/293 Sequence Identity: 17% (16 aa) MFALISGELPFYDM------------KSIQEGKFAFDAASWKIVS-----------------KDARELIEKMLVVNTEKRITLPEAMNHSWF .. ...|..||.. . | .... || | .| ......|...| .. .||.| .....| || LYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Efhand | 3710.AA | efhand | 118-146 | 34 | 5e-06 | 26.52 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 118-146 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) TPKDIFALIDKNGNGFITVQDIKEVVKRL |..|...||.|.|.|.... .|..|.| ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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EFh | 3710.AA | EFh | 118-146 | 34 | 6e-06 | 26.94 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 118-146 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) TPKDIFALIDKNGNGFITVQDIKEVVKRL |..|...||.|.|.|. .. |...|.| EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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EFh | 3710.AA | EFh | 217-245 | 13 | 0.040223 | 7.75 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 217-245 Range on HMM: 1-29/29 Sequence Identity: 13% (4 aa) KLQKAFKYMDASETNSISKDDIMDVFARE .....|. .|. |.... .|.... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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Efhand | 3710.AA | efhand | 217-245 | 17 | 0.152762 | 10.06 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 217-245 Range on HMM: 1-29/29 Sequence Identity: 17% (5 aa) KLQKAFKYMDASETNSISKDDIMDVFARE .|...|| .|. |.... ...... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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Efhand | 3710.AA | efhand | 266-283 | 38 | 30.091354 | 1.66 | Pfam | 12-29 (29) | Show / Hide |
Range on Protein: 266-283 Range on HMM: 12-29/29 Sequence Identity: 38% (7 aa) DKKGNLNFEGFCDVMRMG |. | ..|| ||..|.. DGDGYIDFEEFCEMMKKL |