Gene 27742 (Tetrahymena)

27742

Species: Tetrahymena
Alias: PreTt27742, TTHERM_01017250, 829, 199.m00035, 27742
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
27742.AA Protein None 614 None Fasta, JSON
27742.NA RNA None 1845 None Fasta, JSON
27742.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 27742.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 27742.AA AMPK 29-281 66 4.8e-200 599.51 In-house 1-254 (254) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-254/254
Sequence Identity: 66% (168 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVERVQRELHILKMIRHPSLIQLYEII-ETPTHIFLVMEYCSKGEVFGYIQQKQRLDEV
|.. ||.|||.|||||..|||||||.||||||.|.||.|...|||.|||.||||..|||..|||||.| |||| ||.|||| | || | || ...||.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLSNMYKKNELLKTACGSPCYAAPEMIEGKKYESPQVDIWSSGVILFALLCGYLPF
||..| | |. |.||.|.. .|||||||||||||.|.||||||||||||.|..|.||||||||||||||||.||.|..|.|||||.||||.|.|||||||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

EDEDTRKLYDKILKGKYGIPSHVSPDAKDLIEKILTVDPEKRMKFDQIKAHKWF
.||.|..||.||..|.| ||...||.|||||...|.|||.||.....|..|.||
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 27742.AA CAMKL 29-281 47 1.7e-149 480.31 In-house 1-297 (297) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-297/297
Sequence Identity: 47% (143 aa)

YVLIKTLGEGAFGKVKLATH-ILTGEYVAIKILEKKKIID-------------VTDVERVQRELHILKMIR---HPSLIQLYEIIETPTH------IFLV
| ..||||.|.||||||||| ..||| |||||..|||| .              .|. |..|| .|.||..   ||  |.|||.||||.|      |.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYCSKGE--VFGYIQQK----QRLDEVEASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINH--NIKIVDFGLSNMYKK-----NELLKTACGSPCY
||||| ||   | ||...    .|..| || .. . |. ...|.|.. .||||.||||.||| |.  ||||.|||.||||..     ...||| ||||.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

AAPEMIEG--KKYESPQVDIWSSGVILFALLCGYLPFEDE--------DTRKLYDKILK-GKYGIPSHVSPDAKDLIEKILTVDPEKRMKFDQIKAHKWF
.|||...|  |.|. |.||||| ||||.|..||||||.|.        .. .|| || . ... |..||| |..||| |.|.|.||||.. .||. |.|.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 27742.AA CAMK 34-281 29 1e-133 433.58 In-house 1-425 (425) Show / Hide 
Range on Protein: 34-281
Range on HMM: 1-425/425
Sequence Identity: 29% (125 aa)

TLGEGAFGKVKLATHILTG------------EYVAIKILEKKKIIDVT-------------------------DVERVQRELHILKM-------IRHPSL
|||.|.||||||..|..|.            . |||||..|||. | .                         | ..|.||..|.|.       ..|| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLYEIIE------------TPTH--------IFLVM---EYCSKG----EVFGYIQQK---------------QRLDEVEASKFYQEILYGIEYLHKLQ
|.|||..|            | ..        ...||   |||| |    ..| ||...                |..| ||... . |. ...|.|.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKPENLLLDINH-----------------NIKIVDFGLSNMYKK------------------------NELLKTACGSPCYAA-PEMIEG-----
.|||||||||.||| |.                 ||||.|||..|....                        ....|| ||.|.|.| ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KKYESPQVDIWSSGVILFALLCGYLPFEDE-------------DTRKLYDKILKGKYG-IPSH-----------------------VSPDAK
        |.| .|..|.|| ||||...||||.||...             . ..|. ||.||||  .|..                       ||...|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIEKILTVDPEKRMKFDQIKAHKWF
||| |.|.|||||||. .|...|.|.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 27742.AA MARK 29-281 46 1.1e-127 419.29 In-house 1-262 (262) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-262/262
Sequence Identity: 46% (122 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVERVQRELHILKMIRHPSLIQLYEIIE--TPTH-IFLVMEYCSKGEVFGYIQQK--QR
| ..||.|.|...|||||.|..||. |||||.||.|. |    . |.||..|.|.. ||  |.|...||  |..| |.|.|||.|.||...||...   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LDEVEASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINH--NIKIVDFGLSNMYKKNELLKTACGSPCYAAPEMIEGKKYESPQVDIWSSGVILFALL
| | || .. . |.....|.|.  .||||.||||.|.| |   |||| |||.|.  . ...|.| ||.| |.|||....|.|. | ||||| ||.|....
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGYLPFE--DEDTRKLYDKILKGKYGIPSHVSPDAKDLIEKILTVDPEKRMKFDQIKAHKWF
|||.||.  . |  .|| |||.||| ||.|||.....|| ..|||.||.|.. ..|  |.|.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 27742.AA AGC 29-281 25 2.7e-120 312.3 In-house 1-395 (395) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-395/395
Sequence Identity: 25% (102 aa)

YVLIKTLGEGAFGKVKLATHI------LTGEYVAIKILEKKK-IIDVT--DVERVQRE------------LHILKMIR----------HPSLIQ-LYEII
. ..|..|.|.|||| |. .        ||.| |.|.|.||. |..    .||....|             .||....          || ... |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETPTH--IFLVMEYCS---------KG-EVFGYIQ---QKQRLDEVEASKFYQE-------ILYGIEYLHK-LQVVHRD-LKPENLLLDINHNIKIVDFG
....|  ...||||..          | | | ..|   ...|.|| .|  .  |       |. ..||||. . ..||| |||||.||| . .||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSNMYK---------------------------------------------------KNELLKTACG--SPCYAAPEMIEGKKYESPQVDIWS--SGVIL
|. . .                                                   |... .| ||  .| | |||..      ....|.||   |...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

FALLCGYLPFEDEDTR----------KLYDKIL------KGKYGIP----------SHVSPDAKDLIEKILTVDPEKRMK----------FDQIKAHKWF
. .|.|| || ....           ....||.      . |  .|          ...||.|||||.| |..|||||            ...||.|.||
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 27742.AA NuaK 29-281 45 1.5e-118 313.4 In-house 1-252 (252) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-252/252
Sequence Identity: 45% (114 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVERVQRELHILKMIRHPSLIQLYEIIETPTHIFLVMEYCSKGEVFGYIQQKQRLDEVE
| ..||||.| .||||||| . ||  ||||   |.|| |  |  .. ||  |.  . ||  |. ||. |    | .|||| |.|| . || ....| | |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLSNMYKKNELLKTACGSPCYAAPEMIEGKKYESPQVDIWSSGVILFALLCGYLPFE
| .|.  |   . | || ...||||| || ||| | |.|| ||||||.|.....|.| |||| || || ..|. |. | || || ||.|...  | .||.
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

DEDTRKLYDKILKGKYGIPSHVSPDAKDLIEKILTVDPEKRMKFDQIKAHKWF
 .| ..|   | .|.|  | . | ||  || ..|.|.|..|    .|  | | 
GHDFKHLVKQISQGAYYEPCKPS-DACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase 27742.AA QIK 29-281 44 3.1e-114 385.82 In-house 1-272 (272) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-272/272
Sequence Identity: 44% (121 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVERVQRELHILKMIRHPSLIQLYEIIETPTHIFLVMEYCSKGEVFGYIQQKQR-----
| . .|.| | |. ||||.|. | . |||||. | . .| .. ... ||  |.||..||  | ||...||   ...|.|||| || | |. .. |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQ-LDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LDEVEASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLSNMYKKNELLKTACGSPCYAAPEMIEGKKYESPQV
               . | || . ...|. ...|.||...|||||| ||.||| | ||||.|||.|| .|. .||.| |||| |||||| |||.|. |.|
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWSSGVILFALLCGYLPFEDEDTRKLYDKILKGKYGIPSHVSPDAKDLIEKILTVDPEKRMKFDQIKAHKWF
|||| ||.|..| || |||  .   .| ...| ||. ||  .| |  .|| . |.||||.|.  .||. |.| 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 27742.AA S_TKc 29-281 37 1.8e-106 360.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-231/231
Sequence Identity: 37% (100 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVERVQRELHILKMIRHPSLIQLYEIIETPTHIFLVMEYCSK--GEVFGYIQQKQR---
| .....|.||||||....|. ||..|||||.           |...||. |||. .|| ...||..... .|...|||||.   |..| ||....|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDEVEASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLSNMYKKNELLKTACGSPCYAAPEMIEGKKYESPQVDIWSSGVILFAL
   ..| .| .. ..|. ..||.|.....||||||||.|||   .||| ||||.  .      .| ||.| | |||..   .|  . .|.|| |.||. .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LCGYLPFEDEDTRKLYDKILKGKYGIPSHVSPDAKDLIEKILTVDPEKRMKFDQIKA-------HKWF
|||| ||.  .  ....||.          ||.|||.|.|.|..|||||.   .. .       | ||
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 27742.AA CAMK1 29-281 42 1.9e-106 310.45 In-house 1-276 (276) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-276/276
Sequence Identity: 42% (117 aa)

YVLIKTLGEGAFGKVKLATHILT---GEYVAIKILEKKKIIDVTDV---ERVQRELHILK---MIRHPSLIQLYEIIETPTHIFLVMEYCSKGEVFGYIQ
|...|..|.|||..|.|.||. |   |. .|||...||| ..  |.   |....|. |.|    | ||  |..||. |...|. ||||... || |  | 
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

QKQRLDEVEASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDIN---HNIK--IVDFGLSNMYKKNE-LLKTACGSPCYAAPEMIEG---KKYESPQVDI
.|    | .|..  ..||  .||.|.. .|||||||||||.  .   . ||  | ||||| ... .| |.|||||.| | |||..|.   | | .  .|.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY-DKACDM

WSSGVILFALLCGYLPFEDED-TRKLYDKILKGKYGIPSH----VSPD-AKDLIEKILTVDPEKRMKFDQIKAHKWF
|| |||.. ||||| || ||.   .|..||.|..|. ||     .|   |||.| . |.|||.||  ..|. .|.|.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 27742.AA BRSK 29-281 44 4e-97 328.96 In-house 1-254 (254) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-254/254
Sequence Identity: 44% (113 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVER-VQRELHILKMIRHPSLIQLYEIIETPTHIFLVMEYCSKGEVFGYIQQKQRLDEV
| | |||| |  |.||| .|  ||. |||||  | | ..   . . | ||  |.|.| ||  ...|.. |.    .|..|. | || | |  .| ||   
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLSNMYKKNELLKTACGSPCYAAPEMIEGKKYESPQVDIWSSGVILFALLCGYLPF
|| ||.. |  .... |   . ||||||||||||   |||| |||.  .  |  .| | |||| || || | | ||   . |.|| ||||.||| | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

EDEDTRKLYDKILKGKYGIPSHVSPDAKDLIEKILTVDPEKRMKFDQIKAHKWF
 |.  |.| .|. .| . .|  . ||. ||  . ..|||.||.   .|. | |.
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase 27742.AA Pkinase 29-281 34 2.2e-95 328.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVERVQ-RELHILKMIRHPSLIQLYEIIETPTHIFLVMEYCSKG----EVFGYIQ--QK
|......|.|.||.|....|. ||. ||.||..|... .  |....  .|..|.|...||  ..||.. |...|| .||||| .|    . | ||.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QRL--DEVEASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNI----KIVDFGLSNM--YKKNELLKTACGSPCYAAPEMIEGKKYESPQVDIWSS
 ..  .| |. ..  .|| |.||.|.  ..||||||||.|.| | .|    || ||||.    | .|. ..| ||.| |.||| | | .| .| ||.|| 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILFALLCGYLPFEDE------DTRKLYDKILKGKYGIPSHVS---------------------PDAKDLIEKILTVDPEKRMKFDQIKAHKWF
|.||. .|||..|| ..      | ......|.....  ..  .                     ...||.|...|..||.||  ..||. |.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 27742.AA MELK 29-281 46 1.6e-94 320.37 In-house 1-254 (254) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-254/254
Sequence Identity: 46% (118 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVERVQRELHILKMIRHPSLIQLYEIIETPTHIFLVMEYCSKGEVFGYIQQKQRLDEVE
| . ...| | |.|||||.||||.. |||||..|...    |. ||. |.. || .||  . ||| .|||   ||.|||||. ||.| || ...||.| |
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQL--GHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

ASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLSNMYK--KNEL-LKTACGSPCYAAPEMIEGKKYESPQVDIWSSGVILFALLCGYL
. .|...|.  | |.|     ||||||||||.| .|..|..||||    |  |..  |.| |||| |||||.|.||.|     |.|| |..|..|.||.|
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFEDEDTRKLYDKILKGKYGIPSHVSPDAKDLIEKILTVDPEKRMKFDQIKAHKWF
||.|.  . .| ||..|.|  | ..|| .|.|. ..| |||.||..  ..  | | 
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 27742.AA TyrKc 29-281 25 3e-23 84.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 29-281
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YVLIKTLGEGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVERVQRELHILKMI--RHPSLIQLYEIIETP-------THIFLVMEYCSKGEVFGYIQ
 .|.|.|||||||.| ..| .   . ||.| | . .      .|   ||. |....  .|| ...|| .. ..         ...||||...|    |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QKQR-LDEVEASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLSNMYKKN-------ELLKTAC--GSP--C---YAAPEMIEGKKYE
 ... |   .  .|   |  | ||||. ...||||   | |.. || .|| |||||   .         .  ...   |.         ||| |  .|. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

SPQVDIWSSGVILFALL-CGYLPFED-----EDTRKLYDKILKG-KYGIPSH--------VSPDAKDLIEKILTVDPEKRMKFDQIKAHKWF
... |.|| || .. ..  |  | ..      . . .. .. .|    .| .         ...  .....    |||.|  | .|  |. |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 27742.AA Pkinase_Tyr 29-174 33 2e-22 76.54 Pfam 1-158 (270) Show / Hide 
Range on Protein: 29-174
Range on HMM: 1-158/270
Sequence Identity: 33% (53 aa)

YVLIKTLGEGAFGKVKLATHI----LTGEYVAIKILEKKKIIDVTD--VERVQRELHILKMI-RHPSLIQLYEIIE--TPT-HIFLVMEYCSKGEVFGYI
 ...|.|||||||.|...|       |.  ||.|.|  |   .  .   |   ||. |.| . .|| ...|| ..       .|..||||. .|    | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QQ----KQRLDEVEASKFYQEILYGIEYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLS
..    ||.|.  .  .. ..|  | |||.  . .||||   | |.. |. .|| ||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
UBA_CAMKL 27742.AA UBA_CAMKL 304-341 48 4.9e-12 41.34 In-house 1-41 (41) Show / Hide 
Range on Protein: 304-341
Range on HMM: 1-41/41
Sequence Identity: 48% (20 aa)

DYDIVKELEQQ--GIDREELIKSLDANNH-NNITTSYYLLL
| .|..|...   |.||||.|.||. |.. | ||. |||||
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL