Gene 15686 (Tetrahymena)

15686

Species: Tetrahymena
Alias: 583, TTHERM_00295760, 3692.m00149, PreTt15686, 15686, 27.m00346
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
15686.AA Protein None 679 None Fasta, JSON
15686.kin_dom Protein Kinase Domain None 316 None Fasta, JSON
15686.NA RNA None 2040 None Fasta, JSON

Protein domain

Protein domains of 15686.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15686.AA Ciliate-E2-Unclassified 306-621 24 1.9e-89 303.48 In-house 1-352 (352) Show / Hide 
Range on Protein: 306-621
Range on HMM: 1-352/352
Sequence Identity: 24% (98 aa)

FHMHEKLGEGCHSIVRRCQKKED---------SPLQSFAVKIISYKDPEYLFEILTPFNFKNPFDFDHKKNQKSSWSQIKIRYSELKCKIKEYKWSKIED
.......|.|....|..||.|..         .  |....|.| .|| |...|... .| |. .... |                               
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQR-K-------------------------------

KMNKGRTYLRKKILQEERVLSLLSHKNIIKYDSFFLEKDKKKAYIVSEYAQGKPLGYYIQNK-----------------RQFSMREIA-----SVAKQTL
       |  .||.|.    .||.|......  |. ..||.. ||| ||..|. | .||...                 ..|. ....       ..| |
-------Y--NKIMQQ----ILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQIL

KAIAHMHSKG-IIHRDLSYNNIMYDPISE--QVKVIDFTVSK-----------------IVTIQKLLTNTGTLNFK----APEMLQGQFYS----HSIDI
... ..|.|. |||||.  .||..|   .  ..|.|||  ||                 |   |.. |..||.|..    |||.|||| |.    ...||
QGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDI

FSLGVNLFALIFGYLPFQDNSDKQ----------------VISNIINHDPLEFYKNQ----DNHDPLLLHFLE----SLLEKDPLKRLTALQALKHPWI
.|||| |....|||.||.||...|                ...||.. ..  .  ..    .. .|   .|..    ..|.|.| ||.|. |.|.|||.
WSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 15686.AA Ciliate-E2 306-621 21 2.1e-83 283.42 In-house 1-365 (365) Show / Hide 
Range on Protein: 306-621
Range on HMM: 1-365/365
Sequence Identity: 21% (90 aa)

FHMHEKLGEGCHSIVRRCQKKED---------------------SPLQSFAVKIISYKDPEYLFEILTPFNFKNPFDFDHKKNQKSSWSQIKIRYSELKC
.  ..|.|.|....|..|.....                        . .|.||.. .. |... ..  .. .|. .                       
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-F-----------------------

KIKEYKWSKIEDKMNKGRTYLRKKILQEERVLSLLSHKNIIKYDSFFLEKDKKKAYIVSEYAQGKPLGYYIQNKRQFS-----------MREIASVAKQT
                   |  ||| .| ..|..|.|.||||.  .| |||... |.| ||.||. | .||.|.....           ..||. . || 
-------------------Y--KKI-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQI

LK---------------AIAHMHSKG-IIHRDLSYNNIMYDPISEQVKVIDFTVSKIVTIQ----------KLLTNTG----------------------
|.               |. ..|||. |||||.  .||..      .|.|||  ||.....          |.... .                      
LQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTI

--TLNFKAPEMLQGQF---------YSHSIDIFSLGVNLFALIFGYLPFQDNSDKQVISNIINHD-PLEFYKNQ---------------DNHDPLLLHFL
  |....|||.|.|.          |....||.|||| |. ..||..||           ..... ...| ...               .....   ...
CGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLI

ES----LLEKDPLKRLT-ALQALKHPWI
      .|.||| ||.| . |.|.|||.
KKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 15686.AA S_TKc 306-621 23 1.1e-63 218.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 306-621
Range on HMM: 1-231/231
Sequence Identity: 23% (77 aa)

FHMHEKLGEGCHSIVRRCQKKEDSPLQSFAVKIISYKDPEYLFEILTPFNFKNPFDFDHKKNQKSSWSQIKIRYSELKCKIKEYKWSKIEDKMNKGRTYL
.....|.|.|  . |..|..|.    . .|.|||.                                                                 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-----------------------------------------------------------------

RKKILQEERVLSLLSHKNIIKYDSFFLEKDKKKAYIVSEYAQG--KPLGYYIQNKRQ------FSMREIASVAKQTLKAIAHMHSKGIIHRDLSYNNIMY
 ..|..| ..|.   |.||.|.  .| .   .. |.| ||. |    |  ||....       |.  .......|...|....||.|||||||   ||. 
-EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILL

DPISEQVKVIDFTVSKIVTIQKLLTNTGTLNFKAPEMLQGQFYSH-SIDIFSLGVNLFALIFGYLPFQDNSDKQVISNIINHDPLEFYKNQDNHDPLLLH
|    ..|..|| .....      |  ||... |||.|    |.. ..|. |.|. |. .. || ||.   . |.. ..|              .| ...
DE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-------------SPEAKD

FLESLLEKDPLKRLTALQALK-------HPWI
|.. .|.||| ||.|| .||.       |||.
FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15686.AA Pkinase 306-621 22 2e-60 211.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 306-621
Range on HMM: 1-293/293
Sequence Identity: 22% (82 aa)

FHMHEKLGEGCHSIVRRCQKKEDSPLQSFAVKIISYKDPEYLFEI----LTPFNFKNPFDFDHKKNQKSSWSQIKIRYSELKCKIKEYKWSKIEDKMNKG
.| ..|.|.|  . |..|..| ..    .|||||.... .  ...    |                                                  
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRL--------------------------------------------------

RTYLRKKILQEERVLSLLSHKNIIKYDSFFLEKDKKKAYIVSEYAQGK----PLGYYIQ--NKRQF--SMREIASVAKQTLKAIAHMHSKGIIHRDLSYN
         .| ...  |.|.||...  .| .  |.. |.| ||..|      |  ||.  ... |  |..|. ....|.|......||.|||||||   
---------SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPE

NIMYDPISEQV----KVIDFTVSK---IVTIQKLLTNTGTLNFKAPEMLQ-GQFYSHSIDIFSLGVNLFALIFGYLPFQDN------SDKQVISNIINHD
||..|    ..    |..|| ..|   .   . . | .||... ||| .. || |....|..|.|. |. ...|..||..       ...|.| .|   .
NILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPP

PLEFYKNQDNHD-----------------PLLLHFLESLLEKDPLKRLTALQALKHPWI
. . . . ..                   . ...|....|.||| ||.|| |.|.|||.
LHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 15686.AA CAMK 386-621 19 4.6e-56 178.8 In-house 36-425 (425) Show / Hide 
Range on Protein: 386-621
Range on HMM: 36-425/425
Sequence Identity: 19% (78 aa)

IKEYKWSKIEDK----------MNKG---------RTYLRKKILQEERVLSLLS-------HKNIIKYDSFFLEKD-----------------KKKAYIV
|| .. .|. ||          ..|          | . ||....| .....|.       |.||||   ..  ..                 .|. |.|
IKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMV

S---EYAQGK----PLGYYIQNKRQ---------------FSMREIASVAKQTLKAIAHMHSKGIIHRDLSYNNIMYDPIS----------------EQV
    ||..|      |  ||. ...               |. || . . .| . |....||..|.||||   ||..|  .                 ..
MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNI

KVIDFTVSKIVTI-------------------------QKLLTNTGTLNFKA-PEMLQG--------------QFYSHSIDIFSLGVNLFALIFGYLPFQ
|.|||  .....                          ||. |  ||. . | ||.|.|              . |. ..|. |.|| |...  ||.||.
KIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFY

DNSDKQVIS-------------NIINHD---PLEFYKN------------------QDNHDPLLLHFLESLLEKDPLKRLTALQALKHPWI
. .|.. ..             .|.. .   | .. ..                  . . ..   ... ..|..|| ||.|. |.|.|||.
GDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 15686.AA CAMKL 393-621 27 9.9e-45 140.58 In-house 31-297 (297) Show / Hide 
Range on Protein: 393-621
Range on HMM: 31-297/297
Sequence Identity: 27% (74 aa)

KIEDKMNKG-RTYLRKK-----------ILQEERVLSLLS---HKNIIKYDSFFLEKDK----KKAYIVSEYAQGKP--LGYYIQNK----RQFSMREIA
|| ||  .  ... .|.           | .| . ...|.   |.||||    .  ...    || |.| ||..|    |  ||...    . .. .|  
KIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEAR

SVAKQTLKAIAHMHSKGIIHRDLSYNNIMYDPISE-QVKVIDFTVSKIVT------IQKLLTNTGTLNFKAPEMLQG--Q-FYSHSIDIFSLGVNLFALI
   .| . |....||.||.|||.   ||. |     ..|.|||  | . .       ||| |  |.... |||..||  . ..   .|| |.|| |.|..
RYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMV

FGYLPFQDNS-------DKQVISNIINHDPLEFYKNQDNHDPLLLHFLESLLEKDPLKRLTALQALKHPWI
.||||| | .       ..    ..|. .  ...      .  . ... ..|...| || |. | ..||| 
CGYLPFDDDTYNKQGKDNI-YLYWKIMCG--YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 15686.AA Ciliate-E2a 416-621 27 1.1e-44 129.48 In-house 53-275 (275) Show / Hide 
Range on Protein: 416-621
Range on HMM: 53-275/275
Sequence Identity: 27% (63 aa)

LSLLSHKNIIKYDSFFLEKDKKKAYIVSEYAQGKPLGYYIQNKRQFSMR--EIASVAKQTL-KAIAHMHSKGIIHRDLSYNNIMYD---PIS---EQVKV
.. |.|.||||   ..  .|..  |.| || .|. |  .|... .|     ||... .| | .....||...|.||||   ||...   . |    ..|.
MRQLDHPNIIKLYEVY--EDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKI

IDFTVSKIV--TIQ-KLLTNTGTLNFKA------PEMLQGQFYSHSIDIFSLGVNLFALIFGYLPFQDNSDKQVISNIINHDPLEFYKNQ--DNHDPLLL
|||  .. .   .. .. .  ||  . |      .| |....|... |..|.|| .. |..|..||.  . .... .. .   . |  ..   . .    
IDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCK-IDFNCPECWEKCSKECK

HFLESLLEKDPLKRLTALQALKHPWI
...  .||||| ||.|| |||.||| 
DLMKKMLEKDPKKRITAQQALNHPWF
Kinase 15686.AA CAMK-Unique 412-621 22 5.2e-41 132.99 In-house 66-363 (363) Show / Hide 
Range on Protein: 412-621
Range on HMM: 66-363/363
Sequence Identity: 22% (69 aa)

EERVLSLLSHKNIIKYDSF----FLEKDKK---------------KAYIVSEYAQGKPLGYYIQN--------------------KRQFSM--REIASVA
|.... ...| ||||   .    |.  |.|               . ||| ||.||. |  .||                     ...||   ...... 
EHQIWKMVDHPNIIKLYDWNNPIFC--DRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIM

KQTLKAIAHMHSKGIIHRDLSYNNIMYDPI---------------SEQVKVIDFTVSKIVTIQKLL----TNTGTLNFKAP--------------EMLQG
 ..| |.|.|||..|.||||   |||.                     .|..||  .. .   |      |  ||. ..||              |.. .
QCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINM

QFYSHSI----DIFSLGVNLFALIFGYLPFQDNSDK--------QVISNIINHDPLEFYKNQDNHD-----PLLLHFLESLLEKDPLKRLTALQALKHPW
| |.       || |||| .. ...|..||  ....          ...|  .|. .| ... .|.     . .  |.. ... || .|..| ..|.|.|
QCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNF-DWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQW

I
|
I
Kinase 15686.AA RSK 410-621 28 1.5e-38 134.42 In-house 48-278 (278) Show / Hide 
Range on Protein: 410-621
Range on HMM: 48-278/278
Sequence Identity: 28% (66 aa)

LQEERVLSLLS-HKNIIKYDSFFLEKDKKKAYIVSEYAQGKPLGYYIQNKRQ---FSMREIASVAKQTLKAIAHMHSKGIIHRDLSYNNIMYDPISEQ--
..| ..|..   |..|...   |  ....| |.. ||  |  |.. .|....   || .| . .. .  .|. |.|..|||||||   ||.|| .| .  
MTERNILERCQQHPFIVTLHYAF--QTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEG

-VKVIDFTVSKIVTIQ---KLLTNTGTLNFKAPEMLQ---GQF-YSHSIDIFSLGVNLFALIFGYLPFQD---NSDKQVISNIINHD-PLEFYKNQDNHD
 .|..||  .|.  ..   .. |  .|... |||||    .|  .... |..|||| .. . .|..|||    |. |... .| . .  |.. .| ..  
HIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTM-PNWQYLS

PLLLHFLESLLEKDPLKRLT-----ALQALKHPWI
.   ...  .|..|| |||.     | . ..|||.
QEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 15686.AA MSK 420-621 30 7.1e-34 111.89 In-house 59-277 (277) Show / Hide 
Range on Protein: 420-621
Range on HMM: 59-277/277
Sequence Identity: 30% (67 aa)

SHKNIIKYDSFFLEKDKKKAYIVSEYAQGKPLGYYIQNKRQFSMREIASVAKQTLKAIAHMHSKGIIHRDLSYNNIMYDPI--SEQVKVIDFTVSKIVTI
.|.|| ..   |  .|. . |.| ||..|  |   |  .. |.  | . .  .   |. |||.||||||||   ||..| .  . .||.|||  ... . 
QHPNIVNLHYAF--QDQCHTYLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQ

Q---KLLTNTGTLNFKAPEMLQ----GQF-YSHSIDIFSLGVNLFALIFGYLPFQ--DNSDK------QVISNIINHDPLEFY-KNQDNHDPLLLHFLES
.   .. .  .|| . |||||.    ..  |. ..|..|||| |. .  |  |||  . . .      . |.  | .    |      | .|   .... 
DEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQW

LLEKDPLKRLTALQALKHPWI
||.||| |||..   ..| |.
LLTKDPKKRLGMNDLRAHEWK
Kinase 15686.AA CAMK1 306-577 23 3.4e-31 87.89 In-house 1-231 (276) Show / Hide 
Range on Protein: 306-577
Range on HMM: 1-231/276
Sequence Identity: 23% (68 aa)

FHMHEKLGEGCHSIVRRCQKKEDS-PLQSFAVKIISYKDPEYLFEILTPFNFKNPFDFDHKKNQKSSWSQIKIRYSELKCKIKEYKWSKIEDKMNKGRTY
.  ....|.|  |.|..|..|| .   . .|.|.|.                                                    |   | ..    
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK---------------------------------------------------KKFMKKKDMQ-K

LRKKILQEERVLSL---LSHKNIIKYDSFFLEKDKKKAYIVSEYAQGKPLGYYIQNKRQFSMREIASVAKQTLKAIAHMHSKGIIHRDLSYNNIMYDPIS
 ......|  ..     ..| ||||   ..   .... |.| |. .|  | . |  | ... .. . . || |.|. .|||||| ||||   |. | ...
-QEALENEIEIMKKVSKIDHPNIIKFYEWY--ESDNHFYLVMELVTGGELFDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKD

EQ--VK--VIDFTVSKIVTIQ--KLLTNTGTLNFKAPEMLQG---QFYSHSIDIFSLGVNLFALIFGYLPFQDNS-DKQVISNIIN
|.  .|  ..||  |||.  .  .. |  ||. . |||.| .   ..|. ..|..| || .. | .|| ||.|.. |..  . |..
EDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKK
Kinase 15686.AA RSK 406-577 28 5.3e-25 86.27 In-house 45-219 (271) Show / Hide 
Range on Protein: 406-577
Range on HMM: 45-219/271
Sequence Identity: 28% (50 aa)

RKKILQEERVLSLLSHKNIIKYDSFFLEKDKKKAYIVSEYAQGKPLGYYIQNKRQFSMREIASVAKQTLKAIAHMHSKGIIHRDLSYNNIMYDPI---SE
| .   |. .|.   | .|.|  . |   | .|.|.. . ..|  |.  ......|| ||.. ..   ..| .. ||.||.||||   || ||      .
RVCWEEERIILRYGHHPFIVKLHYVF--QDEGKVYMIMDFMRGGDLFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPG

QVKVIDFTVSKIVTIQKLLTNT--GTLNFKAPEMLQGQFYSHSIDIFSLGVNLFALIFGYLPFQDNSDKQVISNIIN
 .|. ||  .| .  .  .. |  .| |. |||.|  | .... |..|.|| ..    |..||| . ..    .| .
HIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQR
Kinase 15686.AA CAMK1 596-621 53 3.6e-13 34.57 In-house 251-276 (276) Show / Hide 
Range on Protein: 596-621
Range on HMM: 251-276/276
Sequence Identity: 53% (14 aa)

HFLESLLEKDPLKRLTALQALKHPWI
.|.  .||.|| ||.|. |.|.||||
DFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 15686.AA TyrKc 306-621 17 3.1e-12 -24.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 306-621
Range on HMM: 1-280/280
Sequence Identity: 17% (61 aa)

FHMHEKLGEGCHSIVRRCQKKEDSPLQSFAVKIISYKDPEYLFEILTPFNFKNPFDFDHKKNQKSSWSQIKIRYSELKCKIKEYKWSKIEDKMNKGRTYL
 .. .|||||.  .|.... |                                                       ... .|  | ..            
ITLGKKLGEGAFGEVYKGTWK-------------------------------------------------------IQVAVKMLKEDA------------

RKKILQEERVLSLL--SHKNIIKYDSFFLEK-----DKKKAYIVSEYAQGKPLGYYIQNKRQ-FSMREIASVAKQTLKAIAHMHSKGIIHRDLSYNNIMY
|. ...| |... |  .|.||..     ...       .  .|| ||. .  |  |....|  ..|..  | . |  .  .. |||..|||||   |...
REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLV

DPISEQVKVIDFTVSKIVTIQ-------KLLTN----TGT--LNFK--APEMLQGQFYSHSIDIFSLGVNLF-ALIFGYLPFQD-----NSDKQVISNII
.    .||. ||  |. ..         .  .      |   |  .  ||| ..   ...  |..| || ..  . .|  |  .      |...|| .. 
GE-NHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK

NHDPLEFYKNQD------NHDPLLLHFLESLLEKDPLKRLTALQALKHPWI
. . ..  .|         .| .     ..  . || .| |  .   |  .
QGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase 15686.AA CAMK 311-342 28 3.3e-07 18.51 In-house 1-42 (425) Show / Hide 
Range on Protein: 311-342
Range on HMM: 1-42/425
Sequence Identity: 28% (12 aa)

KLGEGCHSIVRRCQKKEDSPL----------QSFAVKIISYK
.||.|  ..|..|. |..  .          | .|.|||. |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKK
Kinase 15686.AA RSK 306-339 35 4.2e-07 21.66 In-house 1-35 (271) Show / Hide 
Range on Protein: 306-339
Range on HMM: 1-35/271
Sequence Identity: 35% (13 aa)

FHMHEKLGEGCHS---IVRRCQKKEDSPLQSFAVKII
.  ||..|.| .|   ....|| |     | .|.|||
YELHECIGQGSFSKVYVCKKCQHKDT--NQHYAMKII
Kinase 15686.AA Pkinase_Tyr 405-490 26 2e-06 22.52 Pfam 46-137 (270) Show / Hide 
Range on Protein: 405-490
Range on HMM: 46-137/270
Sequence Identity: 26% (24 aa)

LRKKILQEERVLSLL-SHKNIIKYDSFFLEKDKK-KAYIVSEYAQGKPLGYYIQN----KRQFSMREIASVAKQTLKAIAHMHSKGIIHRDL
.|.. ..| .... | .|.||...    .....  . ||| ||...  |  | ..    |....| .. . . |  |. .. .||..|||||
CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 15686.AA RSK 601-621 38 3e-06 18.7 In-house 246-271 (271) Show / Hide 
Range on Protein: 601-621
Range on HMM: 246-271/271
Sequence Identity: 38% (10 aa)

LLEKDPLKRLTA-----LQALKHPWI
.|. || .||.|      |...|||.
MLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 15686.AA MSK 308-340 25 0.000236 10.62 In-house 1-33 (277) Show / Hide 
Range on Protein: 308-340
Range on HMM: 1-33/277
Sequence Identity: 25% (9 aa)

MHEK--LGEGCHSIVRRCQKKEDSPLQSFAVKIIS
. ..  .|.|  .|.|.| ....   . .|.||.|
LKVLGTGGYGKFFICRKCVHHDTG--KLYAMKILS
Kinase 15686.AA RSK 308-340 20 0.00125 9.57 In-house 1-33 (278) Show / Hide 
Range on Protein: 308-340
Range on HMM: 1-33/278
Sequence Identity: 20% (7 aa)

MHEK--LGEGCHSIVRRCQKKEDSPLQSFAVKIIS
. ..  .| | ....|.|. .     | .|.|...
LKVLGQGGYGKVFLCRKCTHHDTG--QIYAMKVLK
Kinase 15686.AA Ciliate-E2a 306-340 25 0.136639 0.48 In-house 1-33 (275) Show / Hide 
Range on Protein: 306-340
Range on HMM: 1-33/275
Sequence Identity: 25% (9 aa)

FHMHEKLGEGCHSIVRRCQKKEDSPLQSFAVKIIS
.  . |.|.|.   |.  |.|..   . ||.|...
YKFIKKIGKGNFGSVYLAQHKQTG--KQFAMKKFI