Gene 15045 (Tetrahymena)

15045

Species: Tetrahymena
Alias: TTHERM_00547930, 15045, 3729.m00049, 341, 71.m00172, PreTt15045
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
15045.AA Protein None 529 None Fasta, JSON
15045.kin_dom Protein Kinase Domain None 258 None Fasta, JSON
15045.NA RNA None 1590 None Fasta, JSON

Protein domain

Protein domains of 15045.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15045.AA Ciliate-E2 15-272 27 3e-88 299.49 In-house 1-365 (365) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-365/365
Sequence Identity: 27% (104 aa)

YNLIKRLGQGQFGDVFLLED-SAQNKFALKIIKKDK-----------------LQKIPQLLQYTQSEIEIM----------------EQIKHPNIMELVS
|..|| .|||.||.|.. .. . |..||.|||. .|                  ..... .... .|| ||                ||..||||.... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

SQK--MDGTFFLVLEYCEGGDLRQHIQSLIKK--------KELSFEQISREFLEILD---------------AFDVLHSNH-IIHRDVKPDNILYKNGHP
. .   | ...||.|||.||||...|..  ||        | .. ..|.. . .||.               |.  |||.. ||||| ||.|||.    .
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----I

KVSDFGFSKNIQQQ-------------------------------DDIAATTLGTPQTMAPEVLERKN---------YTYSADIYGLGFILYFMIYQKYP
|..|||.||.....                               .... |..|||  ||||.|..|.         |.|..||. || |||.|.. |.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FNSVHYELIVEQIKKQKINFPE---------------SGLHVDEDIKQIIKR----MLSYNPQLRPS-IDEIRQIPYF
|         .|||..||.||.               | ...... |..||.    || ..|. |.. ...| . |.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 15045.AA Ciliate-E2-Unclassified 15-272 27 8.3e-88 298.03 In-house 1-352 (352) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

YNLIKRLGQGQFGDVFLLEDSAQNKF-----ALKIIKKDKLQKIPQLLQYTQSEIEIMEQ------------------IKHPNIMELVSSQKMDGTFFLV
|..|| .|||.||.|...... |...     . ||......|.  .  .. ....|....                  ..||.|. ..   . . ....|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYCEGGDLRQHIQSLIK--------------KKELSFEQIS-----REFLEILDAFDVLHSNH-IIHRDVKPDNILYKNG----HPKVSDFGFSKNIQQ
.||||||||.|.|..  |              .|... .|..     . | .||.... ||... ||||| ||.|||..|.    ..|..|||.||..||
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

Q---------------DDIAATTLGTPQTM----APEVLERKNYT----YSADIYGLGFILYFMIYQKYPFNSVHYEL----------------IVEQIK
.               .... |. |||..|    |||||...||     |..||..|| |||.|....|||..  .|                 . ..||
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

KQKINFPESGL-----HVDEDIKQIIK----RMLSYNPQLRPSIDEIRQIPYF
...|.||..       |...  | .|.    .|| .||  |.....| . |.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 15045.AA AGC 15-272 20 5.3e-84 216.3 In-house 1-395 (395) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-395/395
Sequence Identity: 20% (82 aa)

YNLIKRLGQGQFGDVFLLED-------SAQNKFALKIIKKDK-LQKIPQ-LLQYTQSE------------IEIMEQIK----------HPNIME-LVSSQ
....| .|.| || |.| ..       . .  .|.|..||..  ... .  ...|..|             .|.|...          ||.|   | .| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KMDGT--FFLVLEYCE--------GGDLRQHIQSL-I-KKKELSFEQISREFLE-------ILDAFDVLHS-NHIIHRD-VKPDNILYKN-GHPKVSDFG
. .     ..|.||..        ||..  ...     |.. .. |..   . |       |. |.. ||| ..||||| .||.|||  . || | .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSKNIQQQD--------------------------------------------------DIAATTLG--TPQTMAPEVLERKNYTYSADIYG--LGFILY
..| . . .                                                  | . |  |  ||. ||||.|    |....|...  || ..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

FMIYQKYPFNSV----------HYELIVEQIK------KQKINFPESG-------LHVDEDIKQIIKRMLSYNPQLRPS----------IDEIRQIPYF
 |.. . ||..           . . . ..|.      ..|. ||  .        ..... | .||..|  .|  |.           ..||.. |.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 15045.AA ULK 15-272 31 1e-77 264.47 In-house 1-324 (324) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-324/324
Sequence Identity: 31% (103 aa)

YNLIKRLGQGQFG-DVFLL--EDSA--QNKFALKIIKKDKLQKIPQL------LQYTQSEIEIMEQIK---HPN--IMELVSSQKMD--GTFFLVLEYCE
|.|...||.|.||  |.    ...   . ..| |.| |.|..|....      .|  ..||.|| ..|   |||  | .|   .. .    .....|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLRQHIQSLIK-----KKELSFEQISREFL-EILDAFDVLHSNHIIHRDVKPDNILYKNG-------------HPKVSDFGFSKNIQ---QQDDIAAT
||||.| |.   |     .|    ||. ..|.  |. .|  ||.. ||||| ||.||| .||             . |..||||.| ..   .....  |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

TL------GTPQTMAPEVLE----RKNYT-YSADIYGLGFILYFMIYQKYPFNSVHYELIVEQ--------------IKKQKINFPE--SGLHVDEDIKQ
..      ||| .|||..|.    .|.|. | .||. || |.| |.| ||||.|  ..  ...              ||.|.|.||   .. .. ...|.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IIKRMLSYNPQLRPSIDEIRQIPYF
.|.||| |..  | |..|| ..| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 15045.AA ULK 15-272 31 2.7e-77 263.08 In-house 1-329 (329) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-329/329
Sequence Identity: 31% (105 aa)

YNLIKRLGQGQFGDVFLLEDSAQN-----KFALKIIKKDKLQKIPQL------LQYTQSEIEIMEQIK--------HPNIMELVSSQKMD--GTFFLVLE
|.|...||.|.|| |.  ..  ..     |.| |.| |.|.......      .|  ..||.|| ..|        |||| .|   .. .    .....|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCEGGDLRQHIQSLIK------KKELSFEQISREFL-EILDAFDVLHSNHIIHRDVKPDNILYKNG-------------HPKVSDFGFSKNIQQQ---DD
||.||||.| |.   |      .|    ||. ..|.  || .|  ||.. ||||| ||.||| .||             . |..||||.| ..     ..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

IAATTL------GTPQTMAPEVLE----RKNYT-YSADIYGLGFILYFMIYQKYP----FNS-V---HYELIVE------QIKKQKINFPE--SGLHVDE
.. |..      ||| .|||..|.    .|.|. | .||. || |.| |.| |.|    ||. .   ...||        |||||...||   .. .. .
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

DIKQIIKRMLSYNPQLRPSIDEIRQIPYF
..|..|.||| |..  | |..|. ..| |
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 15045.AA S_TKc 15-272 28 3.5e-75 256.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

YNLIKRLGQGQFGDVFLLEDSA-QNKFALKIIKKDKLQKIPQLLQYTQSEIEIMEQIKHPNIMELVSSQKMDGTFFLVLEYCEG--GDLRQHIQSLIKKK
| ... .|.| || |..  .   . ..|.||||           . ...||.|... .||||  |  .    . ...|.|||.|  |||...|..  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

E---LSFEQISREFLEILDAFDVLHSNHIIHRDVKPDNILYKNGHPKVSDFGFSKNIQQQDDIAATTLGTPQTMAPEVLERKNYTY-SADIYGLGFILYF
    ..  .. . . .|..| . .||..|||||.||.|||  . | |..|||... .        |  |||  ||||||    |.. ..|.. .| ||| 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MIYQKYPFNSVHYELIVEQIKKQKINFPESGLHVDEDIKQIIKRMLSYNPQLRPSIDEIRQ-------IPYF
|.. . ||   ..... ..|.             ... |..|...| ..|. ||.. |. |        |.|
MLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15045.AA CAMK 20-272 21 5.6e-71 227.73 In-house 1-425 (425) Show / Hide 
Range on Protein: 20-272
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)

RLGQGQFGDVFLLEDS-AQ------------NKFALKIIKKDKLQK------------------------IPQLLQYTQSEIEIMEQ-------IKHPNI
 ||.|.|| |.| ..   .             |.| |||.|.||..                         |. ..  ..||||| .       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

MELVS---------------SQKM-----DGTFFLVL---EYCEGG----DLRQHIQSL-----------IKKKE--LSFEQISREFLEILDAFDVLHSN
  |                 . ..     |  ...|.   |||.||    || ..|..            |  ..  .. .. .| |  |..| . .||.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

HIIHRDVKPDNILY-KN-----------------GHPKVSDFGFSKNIQQ-----------------------QDDIAATTLGTPQTMA-PEVLERKN--
.|.||| ||.|||. .|                 .  |..||||.. ...                       ...   |  |||  || ||||..|   
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

------------YTYSADIYGLGFILYFMIYQKYPFNSV-------------HYELIVEQIKKQKINFPES----------------------GLHVDED
            |....|.  .| |||.|   ..||..              ... . |.|.| | .||..                        .|...
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQE

IKQIIKRMLSYNPQLRPSIDEIRQIPYF
 |. |..|| ..|. |..|... . | .
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 15045.AA CAMKL 15-272 30 1.1e-68 218.22 In-house 1-297 (297) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-297/297
Sequence Identity: 30% (92 aa)

YNLIKRLGQGQFGDVFLLED-SA-QNKFALKIIKKDKLQKIPQLLQY-----------TQSEIEIMEQIK---HPNIMELVSSQKMDGT------FFLVL
|...| ||.| || | | .. .  . | | |||.|.|....|. ..             . ||.||....   ||||. |      . .      ..||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCEGGD--LRQHIQSLIKKK-ELSFEQISREFLEILDAFDVLHSNHIIHRDVKPDNILYK-NG--HPKVSDFGFSKNIQQQ----DDIAATTLGTPQTM
|||.||.  | ..|..  ...  .. ..  | |  |..| . .||..|.||| ||.|||   ||    |..|||||  .. .    ..   |  |.|  |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLER--KNYT-YSADIYGLGFILYFMIYQKYPFNSVHYE-----LIVEQIKKQKINFPESG--LHVDEDIKQIIKRMLSYNPQLRPSIDEIRQIPYF
|||....  | |  . .||  .| |||.|.. ..||.  .|.      | .  .|...   .    .||. | ...|..||  ||  ||.|..|.. | .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 15045.AA Pkinase 15-272 29 2e-66 231.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

YNLIKRLGQGQFGDVFLLEDSAQNK-FALKIIKKDKLQKIPQLLQYTQS--EIEIMEQIKHPNIMELVSSQKMDGTFFLVLEYCEGG----DLRQHIQSL
| .....|.| || |..  .   .| .|.|||||.   . .. .|.     ||.||  ..|||| .|  .   ..   .|.||||||    ||  .|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-

IKKKEL--SFEQISREFLEILDAFDVLHSNHIIHRDVKPDNILYK-NGHP----KVSDFGFSKNI-QQQDDIAATTLGTPQTMAPEVLE-RKNYTYSADI
 ... .  | ... . ...|| . . .||. |||||.||.|||.. |||.    |..|||..| .    .  . |  |||  |||||.  .. |....|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YGLGFILYFMIYQKYPFNSV-------HYELIVEQIKKQKINFPESGLHVD-----------------EDIKQIIKRMLSYNPQLRPSIDEIRQIPYF
...| ||| |.  . || .        ....|..  ...     .    .                  |. |..||..| ..|. ||....| | |.|
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 15045.AA Ciliate-E2b 15-272 27 1e-58 177.09 In-house 1-272 (272) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-272/272
Sequence Identity: 27% (77 aa)

YNLIKRLGQGQFGDVFLLED--SAQNKFALKIIKKDKLQKIPQLLQYTQSEIEIMEQIKHPNIMELVSSQKMDGTFFLVLEYCEGGDLRQHIQSLIKKKE
   || ||.|||| |.|     . .. .|.| |.| .. .   .  . ..|....| ..||.|| .. | | |    ...|.| |..|   |   |..  
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQ-NMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIRE-IGRLL

LSFEQISREFLEILDAFDVLHSNHIIHRDVKPDNILYKN-GHPKVSDFGFSKNIQQQDD---IAATTLGTPQTMAPEVLE-----RKNYTYSADIYGLGF
|| ..    . .|. ..  ||.. ||.||.|| ||.  . |..|  |.| .| .... .      |  |||  ||||...      | |||..||. .| 
LSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGI

ILYFMIYQKYPF--NSVHYELIVEQIKKQ--KINFPESGLHVDEDIK--QIIKRMLSYNPQLRP--SIDEIRQIPYF
.||...  . |.       . | ..| |.  .|.||    .  . ..  ... ..|. .|..|.  |..     |.|
CLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPS---YCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF
Kinase 15045.AA Ciliate-E2c 15-272 27 2e-55 190.42 In-house 1-310 (310) Show / Hide 
Range on Protein: 15-272
Range on HMM: 1-310/310
Sequence Identity: 27% (85 aa)

YNLIKRLGQGQFGDVFLL----EDSAQNK-------FALKIIKKDKL----QKIPQLLQYTQSEIEIMEQIKHPNIMELVSSQKMDGTFFLVLEYCEGGD
..  . ||.|..| |..     ... . .       || |..    .     ..   .     ||..| . .||.| . ..  . |  ..|..|||.||.
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT

LRQHIQSLIKKK-ELSFEQISREFLEILDAFDVLHSN-HIIHRDVKPDNILYKNGHPKVSDFGFSKNIQQQDDIAAT----TLGTPQTMAPEVLER-KNY
| |    .|..| ... .|.   |  |. || .||..  |.|||.|| ||| .|| .|  |||||| .| . .   .      |||. |||..||. . |
LEQ----YIYHKPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYY

TYSADIYGLGFILYFMIYQKYPFN----------------SVHY--ELIVEQIK---------------KQKINFPES-GLHVDEDIKQIIKRMLSYNPQ
|. .||  ||  ||.|.. |.|.                 .     . ... |.               .|.|.|||.    .....||.|..||.. . 
TEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEE

LRPSIDEIRQIPYF
.| . |||.  . .
KRIDWDEIFNHECI
Kinase 15045.AA RSK 18-272 30 3.8e-53 182.89 In-house 1-278 (278) Show / Hide 
Range on Protein: 18-272
Range on HMM: 1-278/278
Sequence Identity: 30% (87 aa)

IKRLGQGQFGDVFLLEDS----AQNKFALKIIKKDKLQKIPQLLQYTQSEIEIMEQIK-HPNIMELVSSQKMDGTFFLVLEYCEGGDLRQHIQSLIKK--
.| |||| .| |||        ..  .| |..|| |. .    . .|  |..|.| .. ||.| .|  . . .| ..|..|||.||.|  |.|    .  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

-KELSFEQISREFLEILDAFDVLHSNHIIHRDVKPDNILYKN----GHPKVSDFGFSKN-IQQQDDIAATTLGTPQTMAPEVLE---RKN-YTYSADIYG
  |    ..   . ||  | . ||. .||||| ||.|||| .    || |..||||.|    ..   . |  .| . ||||.|    ... .. ..|.. 
FSEDEACFY---MAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWS

LGFILYFMIYQKYPFNS---VHYELIVEQIKKQK--INFP--ESGLHVDEDIKQIIKRMLSYNPQLRPS-----IDEIRQIPYF
|| ..| |   . || .    . . | ..|.| |   ..|  ..   . .. | .|..||  .|. |..     ..||.| |.|
LGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQY---LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 15045.AA TyrKc 15-270 22 2e-15 26.84 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-270
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YNLIKRLGQGQFGDVFL--LEDSAQNKFALKIIKKDKLQKIPQLLQYTQSEIEIMEQI--KHPNIMELVSSQKMD-------GTFFLVLEYCEGGDLRQH
  |.| || |.|| |..  .      . | | .|.|.       ..   .|..|| ..  .||||  |.     .       .  ..|.||...|||...
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IQSLIKKKELSFEQISREFLEILDAFDVLHSNHIIHRDVKPDNILYKNGH-PKVSDFGFSKNIQQQ-------DDIAATTLGTPQT------MAPEVLER
...  .|  |. ..     . | .  . |||...||||    |.|....|  |.|||| |..|          | . ... .   |      ||||..  
LRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

KNYTYSADIYGLGFILY--FMIYQKYPFNS----VHYELIVEQIKKQKINFPESG------LHVDEDIKQIIKRMLSYNPQLRPSIDEIRQIP
. .|   |..  |  ..  |   |. . .     .  . ..|..|. .   .          .  ... ||.|.   ..|  ||.  ||... 
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 15045.AA Pkinase_Tyr 62-106 30 0.001343 12.81 Pfam 52-100 (270) Show / Hide 
Range on Protein: 62-106
Range on HMM: 52-100/270
Sequence Identity: 30% (15 aa)

SEIEIMEQI-KHPNIMELVSSQK-MDGT--FFLVLEYCEGGDLRQHIQS
.|..|| |. .||||  |.      ..    ..|.||...|||. . ..
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK
Kinase 15045.AA Pkinase_Tyr 15-31 41 0.003273 11.5 Pfam 1-17 (270) Show / Hide 
Range on Protein: 15-31
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

YNLIKRLGQGQFGDVFL
  ..| ||.|.||.|..
ITFGKKLGEGAFGEVYK
Kinase 15045.AA Pkinase_Tyr 132-170 40 0.012075 9.58 Pfam 127-165 (270) Show / Hide 
Range on Protein: 132-170
Range on HMM: 127-165/270
Sequence Identity: 40% (16 aa)

LHSNHIIHRDVKPDNILYK-NGHPKVSDFGFSKNIQQQDD
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LESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDD