Gene 12851 (Tetrahymena)
12851
Sequence
Protein domains of 12851.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 12851.AA | MARK | 1149-1415 | 47 | 5.3e-155 | 509.94 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-262/262 Sequence Identity: 47% (130 aa) FIFGKVLGLGSYAVVRVVQDQNTKEKYALKTYEKKKLQDPQKRKNVAREVKILSKIKHLNIIRLYDVIE--TNSQ-LHLLMEYPCSTPLNAHIKSKPHRK . ..|..| ||||.|.......|..|.|.|.|||.||.|||..||| ||..|..|..| |||.|..||| |... ..| ||| ....| .||..|... YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LCEEEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDSNT-QTVKLIDFGFSIALAPGTKLNIFCGTPSYMAPEIVNKKDYT-FPVDTWALGILLFKAL |.||||..||.|.|.||.|||.|.|||||||.||.| |.|. . .|.||||||| ||.|||.|||||.||||||..||.|. ..||.|.||..|. . LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV NGNFPFREFQVINKYTKNLGQDDKELYRRINSCKLDFQPHVSSQARSLISKILRHNSNERYTPEQILQDEWF |.|||. . .||.||||..|...| |. .||| ..|.||...| .| .|| | |.|....|. CGYFPFD----------GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | 12851.AA | CAMKL | 1149-1415 | 37 | 1e-131 | 422.71 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-297/297 Sequence Identity: 37% (113 aa) FIFGKVLGLGSYAVVRVVQD-QNTKEKYALKTYEKKKLQ-DPQKRKN-----------VAREVKILSKIK---HLNIIRLYDVIETNSQ------LHLLM ...||.|| ||...|. .. ..|.||.| | ..|||.. ||...|| . ||..|..... | |||.||.|||| . ..| | YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYPCSTP--LNAHIKSKPHRK--LCEEEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDSNTQ-TVKLIDFGFSIALAP-----GTKLNIFCGTPSYM || .. | .|....||. . |.||. .| |.|.||.|||.. |||||||.||.| |.| ..|.||||||. | | ||..|||.|.|| EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEIVNK--KDYT-FPVDTWALGILLFKALNGNFPFREFQVINKYTKNLGQDDKELYRRINSCKLDFQP---HVSSQARSLISKILRHNSNERYTPEQIL ||||... |.| ..|| |..|..|. . |..||.. . | .|.|.. ...... | . | ||| ..|.||.|.| .| ..|.| .||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-K----QGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM QDEWF ...|. NHPWM |
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Kinase | 12851.AA | CAMK | 1154-1415 | 25 | 1.6e-113 | 367.27 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 1154-1415 Range on HMM: 1-425/425 Sequence Identity: 25% (110 aa) VLGLGSYAVVRVVQDQNTK------------EKYALKTYEKKKLQD-------------------------PQKRKNVAREVKILSK-------IKHLNI .|| ||...|. ... ||. .|.| | ..||||.| |..|||| ||..|..| ..| || TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IRLYDVIE------------TNSQ--------LHLLM---EYPCST----PLNAHIKSKPH-------------RKLCEEEAKVIFSQLVEAVKYCHRKS |.||.|.| | |. ... | || | .|..... ....|.||. .| |...||.||| . IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN IVHRDIKLENVLYDSNT----------------QTVKLIDFGFSIALAP------------------------GTKLNIFCGTPSYMA-PEIVNKKD--- |||||.|.||.|.|.| ..|.|||||.. . | | |.. |||||.||| ||..|.| IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN -----------YTFPVDTWALGILLFKALNGNFPFREFQVINKYTKN--LGQDDKELYRRINSCKLDFQPH----------------VSSQ--------A |....| |..|..|. | | .||.. . . . .|..|.||...| ..| || |. .| . . MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-DEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC RSLISKILRHNSNERYTPEQILQDEWF ..||.|.|. . ..|.| ||.|...|. KDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 12851.AA | S_TKc | 1149-1415 | 27 | 7.7e-86 | 292.41 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-231/231 Sequence Identity: 27% (78 aa) FIFGKVLGLGSYAVVRVVQDQNTKEKYALKTYEKKKLQDPQKRKNVAREVKILSKIKHLNIIRLYDVIETNSQLHLLMEYPCST---PLNAHIKSKPHRK . .....| |....|. ... .|....|.| ... ||..||.| .| ||..||||... . |.. ||| |.. | .||...... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEY-CDGDLGDLFDYIKKRGRHG ----LCEEEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDSNTQTVKLIDFGFSIALAPGTKLNIFCGTPSYMAPEIVNKKDYTF-PVDTWALGILLF . | .|. .. |...|..|||.. |.|||.| ||.| |. ..|..|||.. | . ||||| |||||.. |.. ..| |..|..|. LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY KALNGNFPFREFQVINKYTKNLGQDDKELYRRINSCKLDFQPHVSSQARSLISKILRHNSNERYTPEQILQ-------DEWF | | ||. ........| |..|...|.|.|. . ..|.| ..|| ..|| EMLCGYPPFP--------------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 12851.AA | Aur | 1149-1415 | 32 | 1.9e-82 | 217.2 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-257/257 Sequence Identity: 32% (87 aa) FIFGKVLGLGSYAVVRVVQDQNTKEKYALKTYEKKKLQDPQKRKNVAREVKILSKIKHLNIIRLYDVIETNSQLHLLMEYPCSTPLNAHIKSKPHRKLCE | .|| || |.. |. ... .|. ..||| .|. .. . ... ||.|| |. .| ||...|. . . |..|| | .....| ... | FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE EEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDSNTQTVKLIDFGFSIALAPGTKLNIFCGTPSYMAPEIVNKKDYTFPVDTWALGILLFKALNGNFP ..| ...|. .|..|||.| |.||||| ||.| |. ..|. ||| |. . . . |||| ||.||.|. ... . || |.||.|.. ..| | QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP FREFQVINKYTKNLGQDDKELYRRIN-SCKLDFQPHVSSQARSLISKILRHNSNERYTPEQILQDEWF | . ....| |.|| ....| .|.| |. ||||||.|....| | .||.. |. FESN-----------ENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI |
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Kinase | 12851.AA | Pkinase | 1149-1415 | 28 | 2.2e-82 | 284.79 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-293/293 Sequence Identity: 28% (85 aa) FIFGKVLGLGSYAVVRVVQDQNTKEKYALKTYEKKKLQDPQKRKNVAR--EVKILSKIKHLNIIRLYDVIETNSQLHLLMEYPCST----PLNAHIKSKP . .|...| ||...|. ....| ...|.|. .|. ....|... .| |..|. ...| ||.||||. |... ... ||| . | ..|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR HRKL--CEEEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDSNTQT---VKLIDFGFSIA--LAPGTKLNIFCGTPSYMAPEIVN-KKDYTFPVDTWA |... |.|.| .. |......|||...|.|||.|.||.|.|.| .. ||..|||.. . ... .. ||||| |||||... ..|. .|| |. HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS LGILLFKALNGNFPFREFQVINKYTKNLGQDDKELYRRINSCKLDFQPHVS---------------------SQARSLISKILRHNSNERYTPEQILQDE .|..|. |.|..||.. . |......|| ...|.|. . . ....|...|. . ..|.|.|||||.. CGCILYEMLCGRPPFPG----HC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP WF || WF |
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Kinase | 12851.AA | AGC | 1149-1415 | 20 | 3.9e-80 | 206.07 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-395/395 Sequence Identity: 20% (83 aa) FIFGKVLGLGSYAVVRVVQDQ------NTKEKYALKTYEKKK---LQDPQKRKNVARE------------VKILSKIK----------HLNIIR-LYDVI | | ||.| ||. |. |.. |.. ||.| .||. . . .. ... .| .||.|.. | .|.. |. FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF ETNSQ--LHLLMEYPC--------STPLNAHIKSK---PHRKLCEEEAKVIFSQ-------LVEAVKYCHR-KSIVHRD-IKLENVLYDSNTQTVKLIDF .... |...||| . . .. . ... ||.|. .... .| |. | |. . |.||| .|.||.| |.. .|| || QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED-GHIKLTDF GFSIALAPG---------------------------------------------------TKLNIFCG--TPSYMAPEIVNKKDYTFPVDTWA--LGILL |.. . . . . ||| || ||||||. |....| |. ||.|. GLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM FKALNGNFPFREF---QVINKYTKNLGQ----DDKELYRRIN------SCKLDFQ----------PHVSSQARSLISKILRHNSNERYT----------P . | | ||. . . . . .|.. .| ..|. | ...|..|..||.| | . ..| . YEMLTGYPPFYGDNPQE-N--------RHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGA EQILQDEWF |.| . .|| EEIKNHPWF |
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Kinase | 12851.AA | Ciliate-E2 | 1149-1415 | 22 | 4.4e-71 | 242.46 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-365/365 Sequence Identity: 22% (90 aa) FIFGKVLGLGSYAVVRVVQD-----------------------QNTKEKYALKTYEKKKLQDPQKRKNVAREVK----------ILSKIKHLNIIRLYDV ..| |..| |....|. ... .... .||.|...|.... . ... ||.. ||....| |||..|.. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC IE--TNSQLHLLMEYPCSTPLNAHIKSKPHRKLCE---------EEAKVIFSQLVE---------------AVKYCHRKS-IVHRDIKLENVLYDSNTQT . ... . | ||| | .||.... ...| .|.| |. |... |..|.| | |.|||||.||.|. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ VKLIDFGFSI---------------ALAPGTKLNI------------------FCGTPSYMAPEIVNKKD---------YTFPVDTWALGILLFKALNGN .|.||||.| . . | .. .|||| ||||||.|.|. |.. .| |.||..|. | |. IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK FPFREFQVINKYTKNLGQDDKELYRRINSCKLDFQ------------------PHVSSQARSLISK----ILRHNSNERYT-PEQILQDEWF .|| .. | ||.||. ..| .. ||.| .| . ..|.| .||||. .|| PPF--------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 12851.AA | Ciliate-E2-Unclassified | 1149-1415 | 25 | 3e-68 | 233.07 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-352/352 Sequence Identity: 25% (89 aa) FIFGKVLGLGSYAVVRVVQDQNTKEKYALKTYEKKKLQDPQKRKNV--------AREVK--------------ILSKIKHLNIIRLYDVIETNSQLHLLM ....|..| |....|. .|. ..|..||.|. |.. .. .. .|. . . | ||. ..|..|...... .. . . | YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM EYPCSTPLNAHIKSKPH---------------RKLCEEEAK-----VIFSQLVEAVKYCHRKS-IVHRDIKLENVLYDSNTQ--TVKLIDFGFSIALA-- || | .||.... ... |..|| .| |.... .|.|.| |.|||||.||.|.|.| . .|.||||.|. . EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN --------------PGTKLNIFCGTPSYM----APEIVNKKDYT----FPVDTWALGILLFKALNGNFPFREFQVINKY---TKNLGQ--DDKELYRRIN . ... |||||.|| |||. .. | . .| |.||..|. | |..|| . . .. |... . ..|.||. |. NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIK SCKLDFQP--------HVSSQARSLIS----KILRHNSNERYTPEQILQDEWF ....|.. |.| .| .|. |.| | |.|.|.||||. || QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 12851.AA | RSK | 1152-1415 | 30 | 2.5e-67 | 230.02 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 1152-1415 Range on HMM: 1-278/278 Sequence Identity: 30% (88 aa) GKVL---GLGSYAVVRVVQDQNTKEKYALKTYEKKKLQDPQK-RKNVAREVKILSKIK-HLNIIRLYDVIETNSQLHLLMEYPCSTPLNAHIKSKPH-RK ||| | |.. ..| ... .|. || | .|.|. || . . .|..||. .. | .|..|... .|.. |.| ||| | |.. . | LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LCEEEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDS--NTQTVKLIDFGFSIALAPG--TKLNIFCGTPSYMAPEIVN---KKD-YTFPVDTWALGI ..|.||.......| ||.. | . |.|||.|.||.|||. | ..||.||||. . . ... ||.| |||||... .. .. .| | ||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV LLFKALNGNFPFRE-FQVINKYTKNLGQDDKELYRRINSCK--LDFQ--PHVSSQARSLISKILRHNSNERYT-----PEQILQDEWF |.. | |. ||. . .. ||. .|| ..| |.. . .| |..||.| | . . |.. |.|.|..|| LMYEMLTGCPPFQGPND----------NNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 12851.AA | Ciliate-E2a | 1149-1349 | 31 | 2.2e-60 | 176.46 | In-house | 1-216 (275) | Show / Hide |
Range on Protein: 1149-1349 Range on HMM: 1-216/275 Sequence Identity: 31% (67 aa) FIFGKVLGLGSYAVVRVVQDQNTKEKYALKTYEKKKLQDPQKRKNVAREVKILSKIKHLNIIRLYDVIETNSQLHLLMEYPCSTPLNAHIKSKPHRKLCE . | |..| |....|...| .|....| | .|| |. ...... .|..|.....| |||.||.| |..... | ||| . | || . . . YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI EEAKVIFSQLV-EAVKYCHRKSIVHRDIKLENVLYD---SNT---QTVKLIDFGFSIAL--APGTKLNIFCGTPSYMAPEIVNKKD------YTFPVDTW .|.. | || ... |.| . |.|||.|.||.|.. .| . .|.||||.. . .. |||| |.|||. | |. |. .| | QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW ALGILLFKALNGNFPF .|. .. | | || SCGVIFYILLCGKPPF |
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Kinase | 12851.AA | QIK | 1149-1415 | 31 | 8.8e-59 | 201.6 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 1149-1415 Range on HMM: 1-272/272 Sequence Identity: 31% (90 aa) FIFGKVLGLGSYAVVRVVQDQNTKEKYALKTYEKKKLQDPQKRKNVAREVKILSKIKHLNIIRLYDVIETNSQLHLLMEYPCSTPLNAHIKSKPH----- . .. .| | .|||.. . .||.| | | | .| | . . . |||.|. ..| .||.||.|.|| . . ...|| . . .. .. . YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM -------------RKLCEEEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDSNTQTVKLIDFGFSIALAPGTKLNIFCGTPSYMAPEIVNKKDYTFP- . |.||. .|.|.. ||.|||.. |||||.| ||.| |.| .|..||||| .| |. .||.| | |||. |.|. | VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMN-IKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK VDTWALGILLFKALNGNFPFREFQVINKYTKNLGQDDKELYRRINSCKLDFQPHVSSQARSLISKILRHNSNERYTPEQILQDEWF || | .|..|. | .|| |. ...| .|. | | . .|. .|| . | . . ||| .||.| | VDIWSMGVVLYVLVCGALPFD------------GKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM |
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Kinase | 12851.AA | TyrKc | 1149-1414 | 21 | 4.2e-13 | -10.87 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1149-1414 Range on HMM: 1-280/280 Sequence Identity: 21% (66 aa) FIFGKVLGLGSYAVVRVVQDQNTKEKYALKTYEK---KKLQDPQKRKNVAREVKILSKI--KHLNIIRLYDVIETN-------SQLHLLMEYPCSTPLNA .||.|| | . .|. . .. |.|.. |. || .|..|. .| ||.||| |. . .| ..||| . |. ITLGKKLGEGAFGEVYKGTWK-----------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD HIKSKPHRKLCEEEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDSNTQTVKLIDFGFSIALAPG-----------------TK--LNIFCGTPSYMA ..... .. || .. . | . | |.| ..|||. |.|...| ||| ||| | .. . .| | | || YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR-----WMA PEIVNKKDYTFPVDTWALGILLFKAL-NGNFPFRE-FQ--VINKYTKNLGQDDKELYRRIN----SCKLDFQPHVSSQARSLISKILRHNSNERYTPEQI || |.. .|. | |. |.... . .| | . | . |. .. .. . . . | | | .. .. ..... ... ..| | ..| PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----F-VCCPDEMYQIMKQCWHEDPEDRPTFSEI LQDEW ... -HECF |
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Kinase | 12851.AA | Pkinase_Tyr | 1149-1340 | 27 | 2.2e-11 | 39.15 | Pfam | 1-205 (270) | Show / Hide |
Range on Protein: 1149-1340 Range on HMM: 1-205/270 Sequence Identity: 27% (59 aa) FIFGKVLGLGSYAVV---RVV-QDQNTKEKYALKTYEKKKLQDPQ-KRKNVAREVKILSKI-KHLNIIRLYDVIE-TNSQ--LHLLMEYPCSTPLNAHIK .|||.|| |.. .| . ...||| . | |. | . ..| .|. ||.||.... .| ||.||| |. . . . ||| . | . . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR SK--PHRKLCEEEAKVIFSQLVEAVKYCHRKSIVHRDIKLENVLYDSNTQTVKLIDFGFSIAL---------APGTKLNIFCGTPSYMAPEIVNKKDYTF .. . ..|. .. . | .. | ..| ..|||. |.| ..| .|| ||| . .. . |.|| |. |||| | . .| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIK-----WMAPECINYGKFTT PVDTWALGILLF | |. |.|.. KSDVWSFGVLMW |
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Kinase | 12851.AA | Ciliate-E2a | 1384-1415 | 31 | 5.7e-09 | 22.58 | In-house | 244-275 (275) | Show / Hide |
Range on Protein: 1384-1415 Range on HMM: 244-275/275 Sequence Identity: 31% (10 aa) VSSQARSLISKILRHNSNERYTPEQILQDEWF .|... |..| | . ..|.|..|.|.. || CSKECKDLMKKMLEKDPKKRITAQQALNHPWF |