Gene 11236 (Tetrahymena)
11236
Sequence
Protein domains of 11236.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 11236.AA | AGC | 110-306 | 29 | 3.2e-79 | 203.64 | In-house | 140-395 (395) | Show / Hide |
Range on Protein: 110-306 Range on HMM: 140-395/395 Sequence Identity: 29% (80 aa) KRHLSEQHTKFYAAE-------ILLGLEALHS-KKIIHRD-IKPENILISSTGHVKITDFGISIFSDKDPKVG--------------------------- .....|....||||| |.|.|| ||| ..||||| .||||||. . ||.|.|||| . .|. .| EGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCN ---YQENNRMSIISQSTQNEEVQSRISD----IKQFQG--TLQYNAPEILKFQEFSYQADFWA--FGILIFMLLKGYHPFVDYNSDDP------DFATYY |.|| || | | . . . . | | | .| ||||| ....| |. .|.|.. .| || || . | ... . .. PNNWQRNN-MS------Q-E-DDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQ NIINGR-----ILQYNET--------PSLSIQAESLISLLLDINQYSRLGAG-------GIEQIKNHQFF .|.||| .... ...| .| .||. || . |||.| |.|.|||| .| KIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 11236.AA | Ciliate-E2 | 38-306 | 21 | 1.7e-73 | 250.49 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 38-306 Range on HMM: 1-365/365 Sequence Identity: 21% (82 aa) FTIVKKIGSGGYGDIYLLKL-----------------------QQDGKYYVQKRI--SKLKLKSHKDSVI----------IEKEIMKTIKSPFIQSLKAS . ..||||.|..|..|. | ....|.| |.. .... .. ..... .||.|......|.| .. . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC KQ--DD-------------------------------------NYVKRHLSEQHTK-------FYAAEILLGLEALHSKK-IIHRDIKPENILISSTGHV | || . .....| .. ||.|.|.|.|| ||||. ||||||||||||. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISDIKQ---------FQGTLQYNAPEILK---------FQEFSYQADFWAFGILIFMLLK ||.|||.| . |.| . ... .... .. . ..........| | . ||. | |||||. ... .|..|.|..|......| KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD--QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF GYHPFVDYNSDDPDFATYYNIINGRILQYN----------------ETPSLSIQAESLISL----LLDINQYSRLGAGGIEQIKNHQFF |..|| ...| .... .. ..| .. ||. .|. .. |.. |.|||.||..| GKPPF-------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF |
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Kinase | 11236.AA | Ciliate-E2-Unclassified | 38-306 | 26 | 1.1e-68 | 234.47 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 38-306 Range on HMM: 1-352/352 Sequence Identity: 26% (95 aa) FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISKLKLKS-----HKDSVIIEK-EIMKTIK-------------------SPFIQSLKASKQDD------ ..|.|.||.||.|..|... ....||..| ..| . .. .|| |. . ..|. .| .||| . .||. YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV ----------NYVK-------------------RHLSEQHTK-----FYAAEILLGLEALHSKK-IIHRDIKPENILISSTG---HVKITDFGISIFSDK .| | ....||..| ||.|.||.||| ||.|. ||||||||||||... | ..||.|||||..... MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ DPKVGYQEN-NRMSIISQSTQNEEVQSRISDIKQFQGTLQYNAPEILKFQEFS----YQADFWAFGILIFMLLKGYHPFVDYNSDDPD-----------F ... .. ..|.|..| .. ... . . | |.|||.|. |. . |..|.|..|.... .| ||.|| |.|... . . NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMP-Q------YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR ATYYNIINGRILQYNETP------SLSIQAESLIS----LLLDINQYSRLGAGGIEQIKNHQFF .|..|. ...|... | .| .|. .|. .|. |. .|. ..|||.||..| KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF |
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Kinase | 11236.AA | S_TKc | 38-306 | 24 | 5.6e-57 | 196.52 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 38-306 Range on HMM: 1-231/231 Sequence Identity: 24% (74 aa) FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISKLKLKSHKDSVIIEKEIMKTIKSPFIQSLKASKQ-----------DD------NYVKRH-------- ..|..|||.|..| |. . .|... |.|. .... | .|.| . |.| |. . | | | |.. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP LSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISDIKQFQGTLQYNAPE ..| |..||...|...|| .||..|||||.||||||... |.||.|||.. . . | ||. | ||| FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------------------TTFCGTPWYMAPE ILKFQEFSY-QADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGRILQYNETPSLSIQAESLISLLLDINQYSRLGAGGIEQ----IKNHQFF .| ... .| |..|.... .| || || . .. ...| | .| ..|. .|. . |..| . | ||.|..| VL---GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 11236.AA | PDK1 | 113-306 | 32 | 3.9e-51 | 154.61 | In-house | 107-307 (307) | Show / Hide |
Range on Protein: 113-306 Range on HMM: 107-307/307 Sequence Identity: 32% (70 aa) LSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGIS----IFSD-----------KDPKVGYQENNRMSIISQSTQNEEVQSRIS ... ..||||||...|| |||..|||||.||||||... .|..||||| . |... . . |.|. |. . | |.| FDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQ----QHNKGMD-----KPEEDKQTR-- DIKQFQGTLQYNAPEILKFQEFSYQADFWAFGILIFMLLKGYHPFVDY-NSDDPDFATYYNIINGRILQYNETPS--LSIQAESLISLLLDINQYSRLGA | | || .| || | | ....| ||.| .|. .. | ||.. .. | |.. .|| ... . |. |.. ||......||.. -CKSFVGTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMK---CQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTS ----GGIEQIKNHQFF ||..|||.| || CDECGGYQQIKAHPFF |
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Kinase | 11236.AA | MAST | 115-306 | 28 | 1.9e-48 | 154.11 | In-house | 98-334 (334) | Show / Hide |
Range on Protein: 115-306 Range on HMM: 98-334/334 Sequence Identity: 28% (70 aa) EQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGISIF----------SDK--------------DPKVGYQE-------------- | .|.| ||. |.|| |||. |.|||.||.|.||.|.||.|.|||| | . ... ... .|.. EWMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKN --NNRMSIISQSTQNEEVQSRISDIKQFQGTLQYNAPEILKFQE-FSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGR--ILQYNET-- . . . .|| . | || ||..| |||....| . | |. || .. .| |. ||.| . . .. ||.| . ..|. QIQQQQEQPQCQQQN-MRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPE----EIFQNILNRNCNEIEWPEGGD ----PSLSIQAESLISLLLDINQYSRLGAG-GIEQIKNHQFF .| | ||. ||. . . ||||. | ...|.| || INDDEAMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF |
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Kinase | 11236.AA | AktR | 110-306 | 33 | 4.1e-46 | 159.52 | In-house | 95-268 (268) | Show / Hide |
Range on Protein: 110-306 Range on HMM: 95-268/268 Sequence Identity: 33% (69 aa) KRHLSEQHTKFYAAEILLGLEALHSK-KIIHRDIKPENILISSTGHVKITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISD---IKQFQGT |...||. ..||.|.|||.|| ||.. .|| ||.||||||. . ||||||||| | | ... . | || KKKFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK---------------------------LQFMMHYDEKAYSFCGT LQYNAPEILKF-QEFSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGRILQYNETPSLSIQAESLIS-LLLDINQYSRLG--AGGIEQIK .| |||... . ...|.|||||.|. .. |. || . | . . .|.. .... .... .| |. .|| ||. |.. ||| . |.|.|| PEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQ----MFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIK NHQFF .| .| SHPWF |
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Kinase | 11236.AA | RSK | 110-306 | 31 | 6.7e-46 | 158.82 | In-house | 95-278 (278) | Show / Hide |
Range on Protein: 110-306 Range on HMM: 95-278/278 Sequence Identity: 31% (66 aa) KRH---LSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISS---TGHVKITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISDIKQFQ ..| .|| .||.||| | .| ||...|||||.|||||| . ||.|.|||| . . . . . . | EKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------RCDHNQWTMTFC GTLQYNAPEILK---FQE-FSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGR-ILQYNETPSLSIQAESLISLLLDINQYSRLGAG--G .|..| |||.|| |. . ..| | .|.|....| |. || |. . .| .|. | . ..|| | .||. .| . |||.| . YTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQD IEQIKNHQFF .|.||.|..| AEEIKQHPWF |
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Kinase | 11236.AA | Pkinase | 110-306 | 26 | 9.4e-43 | 152.25 | Pfam | 100-293 (293) | Show / Hide |
Range on Protein: 110-306 Range on HMM: 100-293/293 Sequence Identity: 26% (60 aa) KRHL--SEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHV----KITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISDIKQFQ .. . ||.. |||. .|| ||| .||..|||||.|||||||...||. ||.|||.. . | . | . | HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------------------------Y-NNS-MTTFC GTLQYNAPEILK-FQEFSYQADFWAFGILIFMLLKGYHPFVDY----NSDDPDFATYYNIINGRILQYNETPSLS-----------------IQAESLIS ||. | |||... |. .. .| |..|.... .| |. || . | .|... . . .. .. | | . ..|. GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK LLLDINQYSRLGAGGIEQIKNHQFF .|. . ..|.. .|||..| .| WCLCKDPKKRPT---AEQILQHPWF |
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Kinase | 11236.AA | SGK | 111-163 | 54 | 5.8e-28 | 83.05 | In-house | 120-172 (283) | Show / Hide |
Range on Protein: 111-163 Range on HMM: 120-172/283 Sequence Identity: 54% (29 aa) RHLSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGIS .|..| .|||||| . || |||..||.|| |||||| . ||...|||| . KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC |
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Kinase | 11236.AA | PKA | 110-161 | 62 | 7.3e-26 | 92.25 | In-house | 94-146 (263) | Show / Hide |
Range on Protein: 110-161 Range on HMM: 94-146/263 Sequence Identity: 62% (33 aa) KRHLSEQHTKFYAA-EILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFG ....|..|.||||| .| | || |||. ||.|| ||||||| . ||.|||||| SGRFSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG |
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Kinase | 11236.AA | RSK | 110-163 | 51 | 5e-22 | 75.54 | In-house | 95-152 (271) | Show / Hide |
Range on Protein: 110-163 Range on HMM: 95-152/271 Sequence Identity: 51% (30 aa) KRHLSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISST----GHVKITDFGIS .. .||. |||.|||.| .| |||..|.||| ||||||.... ||.||.||| . QKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA |
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Kinase | 11236.AA | AGC | 38-108 | 22 | 2e-19 | 45.47 | In-house | 1-105 (395) | Show / Hide |
Range on Protein: 38-108 Range on HMM: 1-105/395 Sequence Identity: 22% (24 aa) FTIVKKIGSGGYGDIYLLKLQ------QDGKYYVQKRISKLK---LKS--HKDSVIIE------------KEIMKTIK----------SPFIQS-LKASK | ..| || |..| || . . |||| | ..| . .| . ...| ..|..... .||| . |. | FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDDNY ||... QDKDH |
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Kinase | 11236.AA | RSK | 204-306 | 33 | 3.4e-19 | 65.3 | In-house | 167-271 (271) | Show / Hide |
Range on Protein: 204-306 Range on HMM: 167-271/271 Sequence Identity: 33% (36 aa) GTLQYNAPEILKFQEFSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGR-ILQYNETPSLSIQAESLISLLLDINQYSRLGA--GGIEQI .| .| |||.|| | .. .|.| ||.| . | |. ||. . |.|. . .| .|. . ..| | .|.. .|... |||| |.||| YTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPM-NIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQI KNHQFF |.| .| KQHPWF |
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Kinase | 11236.AA | SGK | 202-306 | 34 | 1.3e-17 | 50.56 | In-house | 185-283 (283) | Show / Hide |
Range on Protein: 202-306 Range on HMM: 185-283/283 Sequence Identity: 34% (37 aa) FQGTLQYNAPEILKFQEFSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGRILQYNETPSLSIQAESLISLLLDINQYSRLGAG-GIEQI | ||. | |||.|. |... | | |.. . .. | || . | | ||||. . . |. | .| .|| .|| .. |||. . ..| FCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQ----QMYDNIINQPL---QIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEI KNHQFF |||.|| KNHPFF |
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Kinase | 11236.AA | TyrKc | 38-306 | 17 | 9.2e-11 | -48.64 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 38-306 Range on HMM: 1-280/280 Sequence Identity: 17% (56 aa) FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRIS----KLKLKSHKDSVIIEKEIMKTI--KSPFIQSLKASKQDD-----------------------NY | ||.|.| .| .|. .. | .|| . . . | .||. . . | | | . .. .| ITLGKKLGEGAFGEVYKGTWK----------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY V-KRH--LSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRIS-DIKQFQG |.. |. .. .. | | | ||||..||||. |.|... ..|||.||| | . . | . | .... . . . . . LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------------ESKDYYRKKEHKGGKTML TLQYNAPEILKFQEFSYQADFWAFGILIF-MLLKGYHPFVD---YNSDDPDFATYYNIINGRILQYNET--------PSLSIQAESLISLLLDINQYSRL . ||| ... .|. . | |.||.... .. | | . . ... . .. .|. . . . . ... . . .| PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--IMKQCWHEDPEDRP GAGGIEQIKNHQFF | |..| TFSEI-----HECF |
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Kinase | 11236.AA | AktR | 38-108 | 28 | 1.4e-08 | 29.59 | In-house | 1-75 (268) | Show / Hide |
Range on Protein: 38-108 Range on HMM: 1-75/268 Sequence Identity: 28% (21 aa) FTIVKKIGSGGYGDIYLLKLQ-QDGKYYVQKRISK--LKLKSHKDSVIIEKEIMK-TIKSPFIQSLKASKQDDNY |.. | .|.|..|. || . ...|.| | |.| .. . .. .| |. ||. .. ||| |. . |.... FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEK |
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Kinase | 11236.AA | SGK | 38-100 | 23 | 1.7e-08 | 21.87 | In-house | 1-91 (283) | Show / Hide |
Range on Protein: 38-100 Range on HMM: 1-91/283 Sequence Identity: 23% (21 aa) FTIVKKIGSGGYGDIYLLKLQQD------------------GKYYVQKRISKLKLK---------SHKDSVIIEK-EIMKTIKSPFIQSLK | . |.|| |..| |. | .| .| |. | ..| . . .|. |.| .|.||| .|. FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLH |
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Kinase | 11236.AA | PKA | 224-306 | 37 | 3.4e-08 | 33.56 | In-house | 181-263 (263) | Show / Hide |
Range on Protein: 224-306 Range on HMM: 181-263/263 Sequence Identity: 37% (33 aa) DFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGRILQYNETPSLSIQA---ESLISLLLDINQYSRLG--AGGIEQIKNHQFF | ||.||||. .| || || | | | ...| |.||.| .. .... .| .||. || . |.| .|...|||| .| DWWALGILIYEMLAGYPPFYDHNRD--PMQIYEKICNGKI-KFP--RHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | 11236.AA | Pkinase | 38-96 | 37 | 5.1e-08 | 29.45 | Pfam | 1-62 (293) | Show / Hide |
Range on Protein: 38-96 Range on HMM: 1-62/293 Sequence Identity: 37% (23 aa) FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISKLKLKSHKDSVII---EKEIMKTIKSPFI ..|..|||||..| |. . . .|| .. |.|.| . || || . | .||| ...|.| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNI |
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Kinase | 11236.AA | S_TK_X | 307-368 | 25 | 5.9e-08 | 33.68 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 307-368 Range on HMM: 1-79/79 Sequence Identity: 25% (20 aa) SGIDWKKVSE--LKEQPPFIPSNQ----DNALLQNFDKEVLQ-----SVDNQKMSQIPHTNQ------FTPYPNFTYEE .||||.|. . .|||.| . . . |||.| ..|.. .|.. . |. .|...||| RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | 11236.AA | MAST | 38-96 | 31 | 7.6e-08 | 21.03 | In-house | 1-61 (334) | Show / Hide |
Range on Protein: 38-96 Range on HMM: 1-61/334 Sequence Identity: 31% (19 aa) FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISKLK--LKSHKDSVIIEKEIMKTIKSPFI |...| |. |.|| || | . .. . |.| | .| |.|..|. | . ...||. FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFV |
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Kinase | 11236.AA | Pkinase_Tyr | 132-163 | 46 | 9.5e-07 | 23.48 | Pfam | 127-158 (270) | Show / Hide |
Range on Protein: 132-163 Range on HMM: 127-158/270 Sequence Identity: 46% (15 aa) LHSKKIIHRDIKPENILISSTGHVKITDFGIS |.||..||||. |.|......|||.||| . LESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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Kinase | 11236.AA | PKA | 38-108 | 35 | 2e-06 | 25.7 | In-house | 1-74 (263) | Show / Hide |
Range on Protein: 38-108 Range on HMM: 1-74/263 Sequence Identity: 35% (27 aa) FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISK-----LKLKSHKDSVIIEKEIMKTIKSPFIQ-SLKASKQDDNY | |.. .|.| .| .| . ...|.|| | ..| || . | |. || |.. ||.||| ..... |||.| FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEH---VHNEKNILQNIKHPFIVKKMYWTFQDDRY |
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Kinase | 11236.AA | RSK | 38-109 | 23 | 9.5e-05 | 13.15 | In-house | 1-76 (271) | Show / Hide |
Range on Protein: 38-109 Range on HMM: 1-76/271 Sequence Identity: 23% (18 aa) FTIVKKIGSGGYGDIYLLKLQ---QDGKYYVQKRISKLKLKSH-KDSVIIEKEIMKTIKSPFIQSLKASKQDDNYV . . ..|| | ....|. | . ...| | | | ... .. | |. . .||| |. . || .| YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKV |
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Kinase | 11236.AA | Pkinase_Tyr | 210-233 | 37 | 0.00167 | 12.49 | Pfam | 182-205 (270) | Show / Hide |
Range on Protein: 210-233 Range on HMM: 182-205/270 Sequence Identity: 37% (9 aa) APEILKFQEFSYQADFWAFGILIF ||| ... .|. . | |.||.|.. APECINYGKFTTKSDVWSFGVLMW |
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Kinase | 11236.AA | RSK | 41-109 | 27 | 0.003204 | 8.06 | In-house | 1-76 (278) | Show / Hide |
Range on Protein: 41-109 Range on HMM: 1-76/278 Sequence Identity: 27% (21 aa) VKKIGSGGYGDIYLLKLQ---QDGKYYVQKRISKLKLKSH-KD--SVIIEKEIMKTIK-SPFIQSLKASKQDDNYV .| | |||| .| . . |..| | ..| |.. . || . | .|..... .||| .|. . |.. .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKL |
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Kinase | 11236.AA | Pkinase_Tyr | 38-54 | 41 | 2.033163 | 2.04 | Pfam | 1-17 (270) | Show / Hide |
Range on Protein: 38-54 Range on HMM: 1-17/270 Sequence Identity: 41% (7 aa) FTIVKKIGSGGYGDIYL |. ||.|.| .|..|. ITFGKKLGEGAFGEVYK |