Gene 10871 (Tetrahymena)
10871
Sequence
Protein domains of 10871.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 10871.AA | Ciliate-E2-Unclassified | 35-358 | 25 | 9.6e-90 | 304.46 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 35-358 Range on HMM: 1-352/352 Sequence Identity: 25% (102 aa) EWVEEIIGQGGFGVVKRVRKKGEQGPTYAMKMMEKYQVSKKNNIQT---------TLNEMF-------------ILRDIQHPFLINMKWAFHDETYLYLV . ..|||||||.|.....| .. ||||.| |.|. |...|.. ..|.. ||....|||...| ..| |. ..|.| YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV MEELKGYDLHFHLVN-------FKLKDDLMLKQKYFDLEQKK---VQLERIKKNTPDTSKGAADNKKIEVDPSCFTENQATQLCLALNYLHNNK-IIHKD || ..| ||.... . ...... |...| |. .| | .. . |....|.||| .. ||| | MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKA------------------------------KFYFAQILQGLEYLHHKNNIIHRD IKPANIIFEDDG---YLRVTDLGISK-----------------KFRPNNNVDISGTPGYI----APEVLCRQNHN----YAVDYYAVGVICYELMLTKKP ||| ||.| ..| |....|.|||| ..... ...|||.|. |||||..||.. |..|....|||.||.. . | IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP YENDKPEKDN----------YNKELLKNILQSQIEVVPYKPGQKPGQIDTTNPINGITKVVAPQDWSNEGIDFMN-----QPTKRIGYD-NIEKVLEHNW .. . |... |.|.|..||.| .|.. .....| .|..||.|..|| | . |.... ..|..|.| | FYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPW F | F |
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| Kinase | 10871.AA | Ciliate-E2 | 35-358 | 23 | 5.7e-78 | 265.35 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 35-358 Range on HMM: 1-365/365 Sequence Identity: 23% (99 aa) EWVEEIIGQGGFG-----VVKRVRKK-----------------GEQGPTYAMKMMEKYQVSKKNNIQTTL----------NEMFILRDIQHPFLINMKWA . ..||||.|| |..|.|. . .. ||||.|.|.|. ..... . ||. ||. ..||..|.|... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FH--DETYLYLVMEELKGYDLHFHLVNFKLKDD---------LMLKQKYFDLEQKKVQLERIKKNTPDTSKGAADNKKIEVDPSCFTENQATQLCLALNY | |....||||| ..| || .. |.|.| . . . ||. .. .... . |.......|||.| FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFK-------------------------TKAEFYIACIILALEY LHNNK-IIHKDIKPANIIFEDDGYLRVTDLGISKKFRPNNNVDI---------------------------------SGTPGYIAPEVLCRQN------- ||... ||| |||| ||.| . ..|.|.|||. ..|. . ||||| |||.| ... LHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ --HNYAVDYYAVGVICYELMLTKKPYENDKPEKDNYNKELLKNILQSQIEVVPYKPGQKPGQIDTTNPINGITKVV-APQDWSNEGIDFMNQ-------- ..|..|....||| ||.. | |. | ||. ... .. | | |. .. . . . ...||.|..|.... KGYDYKCDIWSLGVILYEMLFGKPPF-------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQK -PTKRIGYDNIEKVLEHNWF | |||. ..|..|.| || DPEKRIT--GWEQILNHPWF |
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| Kinase | 10871.AA | AGC | 37-358 | 17 | 6.1e-78 | 200.27 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 37-358
Range on HMM: 1-395/395
Sequence Identity: 17% (85 aa)
VEEI--IGQGGFGVVKRVRKKG-----EQGPTYAMKMMEKYQ-VSKKN--NIQTTLNE------------MFILRDIQ----------HPFLIN-MKWAF
| . ||.|.|| | ||||. | ||||...| . .|. .. |..| || .. |||... .. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF
HDETY--LYLVMEELK---------GY-DLHFHLVNFKLKDDLMLKQKYFDLEQKKVQLERIKKNTPDTSKGAADNKKIEVDPS---CFTENQA----TQ
.|... ||.||| .. | .|..|| . .|.|..| .
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGR----------------------------------------------RKEGRFDEERARFYAAE
-------LCLALNYLHN-NKIIHKD-IKPANIIFEDDGYLRVTDLGISKKFRPNNNV-------------------------------------------
..||| |||. ..||| | .|| || . .||... || | .|... ....
MQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDT
---------DISG--TPGYIAPEVLCRQNHNYAVDYYA--VGVICYELMLTKKPYENDKP---------EKDNYNKEL----------------------
. | || |.|||.| ...|.|... .|.. ||.. . |. .| | ... ..| .
TRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPE
-------LKNILQSQIEVVPYKPGQKPGQIDTTNPINGITKVVAPQDWSNEGIDFMN-QPTKRIGYDN-------IEKVLEHNWF
.|.... ... |.||.|. . .| . .| ||
DRWFSPEAKDLIKK----------------------------------------LLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
|
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| Kinase | 10871.AA | S_TKc | 35-358 | 20 | 8.3e-42 | 146.12 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 35-358
Range on HMM: 1-231/231
Sequence Identity: 20% (70 aa)
EWVEEIIGQGGFGVVKRVRKKGEQGPTYAMKMMEKYQVSKKNNIQTTLNEMFILRDIQHPFLINMKWAFHDETYLYLVMEELKG--YDLHFHLVNFKLK-
. ..||.|.||.|...|.|. | .|.|.. .....|. ||. .||...... .|.| ..||.||| . | ||. .... . .
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----DDLMLKQKYFDLEQKKVQLERIKKNTPDTSKGAADNKKIEVDPSCFTENQATQLCLALNYLHNNKIIHKDIKPANIIFEDDGYLRVTDLGISKKFR
. ..|. |.|.||.|.|...||| |.||.|| . . . ..| |.....
LRFPFPE-HARFYM-----------------------------------------YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-
PNNNVDISGTPGYIAPEVLCRQNHNY-AVDYYAVGVICYELMLTKKPYENDKPEKDNYNKELLKNILQSQIEVVPYKPGQKPGQIDTTNPINGITKVVAP
. ||| |.||||| ... ..| ...|.| ||.. . |.. ....|.|.
----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFKKIG---------------------------------
QDWSNEGIDFMN-----QPTKRIGYDNIEK----VLEHNWF
| |..||.. |.||.. . . . | ||
---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 10871.AA | Ciliate-E2b | 184-278 | 37 | 1.2e-33 | 99.69 | In-house | 110-214 (272) | Show / Hide |
Range on Protein: 184-278 Range on HMM: 110-214/272 Sequence Identity: 37% (39 aa) QLCLALNYLHNNKIIHKDIKPANIIFEDDGYLRVTDLGISKKFRPNNN-----VDISGTPGYIAPEVLC-----RQNHNYAVDYYAVGVICYELMLTKKP ..||.| ||||..||. |||| ||. .||.. |.|..| . .| | ||| | |||... . .|.|| ..||.. ||.| . | SICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVP YENDK . |. WAEDV |
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| Kinase | 10871.AA | Pkinase | 182-358 | 23 | 1.7e-30 | 108.92 | Pfam | 114-293 (293) | Show / Hide |
Range on Protein: 182-358 Range on HMM: 114-293/293 Sequence Identity: 23% (47 aa) ATQLCLALNYLHNNKIIHKDIKPANIIFEDDGYL----RVTDLGISK---KFRPNNNVDISGTPGYIAPEVLC-RQNHNYAVDYYAVGVICYELMLTKKP ..|.. .|.|.|...||| |.||.|| . ..|.. ...| |..| . . .. |||.|.||||. .| . ..|| ...|.|.||... . | MYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP YEND-KPEKDNYNKELLKNILQ-------------SQIEVVPYKPGQKPGQIDTTNPINGITKVVAPQDWSNEGIDFMNQ-----PTKRIGYDNIEKVLE . .. ... . ......|.. | . ... . . . || |..||.. |.||.. .| .|. FPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPT---AEQILQ HNWF | || HPWF |
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| Kinase | 10871.AA | CAMK | 184-303 | 21 | 3.1e-27 | 84.22 | In-house | 187-370 (425) | Show / Hide |
Range on Protein: 184-303 Range on HMM: 187-370/425 Sequence Identity: 21% (39 aa) QLCLALNYLHNNKIIHKDIKPANIIFEDDG----------------Y-LRVTDLGISKKFRPNNNV-------------------------DISGTPGYI |.| |..|.|...|.| |.|| || . |.. . . ..| | ..||.|..| . |||.|. QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM A-PEVLCRQN--------------HNYAVDYYAVGVICYELMLTKKPYENDKPEKDNY-------NKELLKNILQSQIEVVPYK | |||| .. .....| ..|||.| . . |.. |. . . .||...|.. . . |.. AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPY |
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| Kinase | 10871.AA | SGK | 182-268 | 40 | 2.7e-24 | 71.54 | In-house | 131-219 (283) | Show / Hide |
Range on Protein: 182-268 Range on HMM: 131-219/283 Sequence Identity: 40% (36 aa) ATQLCLALNYLHNNKIIHKDIKPANIIFEDDGYLRVTDLGISK-KFRPNNN-VDISGTPGYIAPEVLCRQNHNYAVDYYAVGVICYELM | .. .|| ||| .||. | || || ..|... || | .| . .|. . ||| | ||||| | | .|| . | . ||.| AAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMM |
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| Kinase | 10871.AA | RSK | 176-299 | 33 | 4.7e-24 | 85.02 | In-house | 100-234 (278) | Show / Hide |
Range on Protein: 176-299 Range on HMM: 100-234/278 Sequence Identity: 33% (46 aa) CFTENQA----TQLCLALNYLHNNKIIHKDIKPANIIFED---DGYLRVTDLGISKKFRPNNNV---DISGTPGYIAPEVLC---RQN-HNYAVDYYAVG ||.|. | .. ||. .|| .||| |.|| ||...| .| ...|| | .|.||...| .| |.|||.| .|. |. |.|.. | CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VICYELMLTKKPYENDKPEKDNYNKELLKNILQSQIEV |. ||. . |. . |.. | ||..|.|.. .. . VLMYEMLTGCPPFQG--PND-NNRKEIMKRIQKGKFSL |
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| Kinase | 10871.AA | AktR | 184-268 | 40 | 4.3e-23 | 83.04 | In-house | 109-199 (268) | Show / Hide |
Range on Protein: 184-268 Range on HMM: 109-199/268 Sequence Identity: 40% (37 aa) QLCLALNYLHNN-KIIHKDIKPANIIFEDDGYLRVTDLGISK--KFRPNNNVDIS--GTPGYIAPEVLCR-QNHNYAVDYYAVGVICYELM | .||| |||.. .|| |.|| || . ||... || | || . . .. . .| ||| |.|||.. . . ||..||..|.|. ||.. QILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMV |
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| Kinase | 10871.AA | RSK | 185-270 | 41 | 1e-21 | 74.39 | In-house | 110-200 (271) | Show / Hide |
Range on Protein: 185-270 Range on HMM: 110-200/271 Sequence Identity: 41% (38 aa) LCLALNYLHNNKIIHKDIKPANIIFEDD----GYLRVTDLGISKKFRPNNNVDIS--GTPGYIAPEVLCRQNHNYAVDYYAVGVICYELMLT . ||..||| .|.| | ||.||.. |. | ....|.| .|. | | . .| |.||||| || | |.|.. ||. || ||| IALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYE-MLT |
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| Kinase | 10871.AA | SGK | 39-125 | 27 | 4.6e-20 | 58.21 | In-house | 5-116 (283) | Show / Hide |
Range on Protein: 39-125 Range on HMM: 5-116/283 Sequence Identity: 27% (31 aa) EIIGQGGFGVVKRVRKKGE-----------------QGPTYAMKMMEKYQVS-------KKNNIQTTLNEM-FILRDIQHPFLINMKWAFHDETYLYLVM .||.|.|| | |..|.. .. |||| | .. ||. .. | || . |||..| . || ...||.|| KVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKLYFVM EELKGYDLHFHL . . | .. .|| DYVNGGEMFYHL |
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| Kinase | 10871.AA | PKA | 41-114 | 41 | 1.7e-18 | 67.78 | In-house | 7-80 (263) | Show / Hide |
Range on Protein: 41-114 Range on HMM: 7-80/263 Sequence Identity: 41% (31 aa) IGQGGFGVVKRVRKKGEQGPTYAMKMMEKYQVSKKNNIQTTLNEMFILRDIQHPFLIN-MKWAFHDETYLYLVME .|.| || |. .|.|. |||||. | .. . . .. ..|| ||. |.|||... |.| |.|..|||.||| LGTGSFGRVMLCRHKHSG-NYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVME |
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| Kinase | 10871.AA | RSK | 37-127 | 32 | 2.5e-18 | 62.2 | In-house | 3-94 (271) | Show / Hide |
Range on Protein: 37-127 Range on HMM: 3-94/271 Sequence Identity: 32% (31 aa) VEEIIGQGGFG---VVKRVRKKGEQGPTYAMKMMEKYQVSKKNNIQTTLNEMFILRDIQHPFLINMKWAFHDETYLYLVMEELKGYDLHFHLVN . | |||| |. |.|... | . |||| .| .. | . . .| |||...||| . . .| ||...|..|. ..| || .|.. LHECIGQGSFSKVYVCKKCQHK-DTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLK |
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| Kinase | 10871.AA | CAMK | 40-114 | 15 | 1.5e-17 | 52.4 | In-house | 1-140 (425) | Show / Hide |
Range on Protein: 40-114 Range on HMM: 1-140/425 Sequence Identity: 15% (22 aa) IIGQGGFGVVKRVRKKGEQG-----------PTYAMKMMEKYQVSKKN-------------------------NIQTTLNEMFILRD-------IQHPFL ..|.|.||.||... | .| .|.|...| ....|. . . ..|. |.. ..|| . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI INMKWAFHD-------------------ETYLYLVM---E |.. .. | ....|.|| | IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIME |
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| Kinase | 10871.AA | RSK | 37-125 | 30 | 1.7e-17 | 60.83 | In-house | 1-92 (278) | Show / Hide |
Range on Protein: 37-125 Range on HMM: 1-92/278 Sequence Identity: 30% (28 aa) VEEI--IGQGGFGVVKRVRKKGEQGPTYAMKMMEKYQVSKKNN-IQTTLNEMFILRDIQ-HPFLINMKWAFHDETYLYLVMEELKGYDLHFHL ... .|.| . ...... . .| |||| .| . ... . .|. | || ..| |||... . ||..|..|||.|| ..| .| || LKVLGQGGYGKVFLCRKCTHH-DTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHL |
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| Kinase | 10871.AA | Pkinase | 35-137 | 21 | 6.4e-17 | 60.91 | Pfam | 1-112 (293) | Show / Hide |
Range on Protein: 35-137 Range on HMM: 1-112/293 Sequence Identity: 21% (24 aa) EWVEEIIGQGGFGVVKRVRKKGEQGPTYAMKMMEKYQVSKKNNIQTTL-NEMFILRDIQHPFLINMKWAFHDETYLYLVMEELKGY----DLHFHLV--- ....||.|.||.|.. ..||.. ..|.| ..| ... ... .. .| |.. ..||. . .. .|.|....|.||| . | ||. .. YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR NFKL--KDDLMLK . .. .. . HGCFYFSEWECKF |
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| Kinase | 10871.AA | AktR | 37-127 | 32 | 1.3e-15 | 56.85 | In-house | 3-94 (268) | Show / Hide |
Range on Protein: 37-127 Range on HMM: 3-94/268 Sequence Identity: 32% (30 aa) VEEIIGQGGFGVVKRVRKKGEQGPTYAMKMMEKYQVSKKNNIQTTLNEMFILR-DIQHPFLINMKWAFHDETYLYLVMEELKGYDLHFHLVN | ...|.|.|| | |.|| . . ||||| | ..| .. |..| |. ..|||..... .| ....|...|| .| .| .|| . VYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKK |
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| Kinase | 10871.AA | PKA | 182-268 | 39 | 1.3e-15 | 58.15 | In-house | 106-193 (263) | Show / Hide |
Range on Protein: 182-268 Range on HMM: 106-193/263 Sequence Identity: 39% (35 aa) AT-QLCLALNYLHNNKIIHKDIKPANIIFEDDGYLRVTDLGISKKFRPNNNVDISGTPGYIAPEVLCRQ-NHNYAVDYYAVGVICYELM |. | .||| |||. ||. | || || ..|.. .|| | .|| . . . ||| |.|||.. . |. .|| | |.. ||.. AASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEML |
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| Kinase | 10871.AA | Ciliate-E2b | 37-121 | 31 | 3.8e-15 | 42.62 | In-house | 1-87 (272) | Show / Hide |
Range on Protein: 37-121 Range on HMM: 1-87/272 Sequence Identity: 31% (27 aa) VEEI--IGQGGFGVVKRVRKKGEQGPTYAMKMMEKYQVSKKNNIQTTLNEMFILRDIQHPFLINMKWAFHDETYLYLVMEELKGYDL ...| |.| || | |.. .. |||| .| |....| |.| .|. ..|||... . .| |. ..|..|| .| .| MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMEL |
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| Kinase | 10871.AA | TyrKc | 35-353 | 14 | 1.6e-09 | -68.84 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 35-353
Range on HMM: 1-280/280
Sequence Identity: 14% (51 aa)
EWVEEIIGQGGFGVVKRVRKKGEQGPTYAMKMMEKYQVSKKNNIQTTLNEMFILRDI--QHPFLINMKWAFHDE-------TYLYLVMEELKGYDLHFHL
....| | ||.| . . | . | ||. .. .. ..|. |.. . .|| .... . .. |..||| .. ||. .|
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL
VNFKLKDDLMLKQKYFDLEQKKVQLERIKKNTPDTSKGAADNKKIEVDPSCFTENQATQLCLALNYLHNNKIIHKDIKPANIIFEDDGYLRVTDLGISKK
. . | . .. . . ..| . .||| ...|| |. |. ... ...| | |..
RKHRPK----------------------------------------LCMKDLLS-FCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRD
FRPN-------NNVDIS---GTPG-----YIAPEVLCRQNHNYAVDYYAVGVICYELM-LTKKPYENDKPEKDNYNKELLKNILQS----QIEV----VP
. . |. . |||.. . . | .. || ..|.. . ..||... . . |.|..... | | .
IYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMS-
YKPGQKPGQIDTTNPINGITKVVAPQDWSNEGID--FMNQPTKRIGYDNIEKVL
| .|.. . . . .| .| .| . .
------------------F--VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
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| Kinase | 10871.AA | RSK | 340-358 | 33 | 0.00165 | 8.67 | In-house | 251-271 (271) | Show / Hide |
Range on Protein: 340-358 Range on HMM: 251-271/271 Sequence Identity: 33% (7 aa) PTKRIGY--DNIEKVLEHNWF |..| | . .| ...| || PHNRLGAGPNGVEQIKQHPWF |
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| Kinase | 10871.AA | RSK | 340-358 | 38 | 0.008632 | 6.47 | In-house | 258-278 (278) | Show / Hide |
Range on Protein: 340-358 Range on HMM: 258-278/278 Sequence Identity: 38% (8 aa) PTKRIG--YDNIEKVLEHNWF | ||.| . .| ...| || PHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 10871.AA | AktR | 336-358 | 32 | 0.013168 | 6.38 | In-house | 244-268 (268) | Show / Hide |
Range on Protein: 336-358 Range on HMM: 244-268/268 Sequence Identity: 32% (8 aa) FMNQPTKRIG--YDNIEKVLEHNWF ... |.||.| ..| . .| || LCKNPNKRLGYYCNGWEEIKSHPWF |
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