Gene 20139 (Tetrahymena)
20139
Sequence
Protein domains of 20139.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 20139.AA | Ciliate-E2c | 11-296 | 49 | 5.70000000001e-191 | 640.73 | In-house | 1-310 (310) | Show / Hide |
Range on Protein: 11-296 Range on HMM: 1-310/310 Sequence Identity: 49% (154 aa) FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQLFAIKMLQLNVF--KQYNISDPLERIMQEIELQKDLDHPHITKYVDAVKTEQNVYIVTEFCNGGN ...|.|||.||.||||||...|....|...|..||||||||..|... ...|..|..|.|..||...|...||||.|..||..|....|...|.||||. IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGT LEQYIYNN-RPKEQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIHDDIPKICDFSISRKSNILNDTYKT----ITGTPLFSSPQILKG-KEYTSKS ||||||.. .|.|...|..||||||.||||..||||.||||||.|||||....||.||..|......|..... ..|||....||||.| ..||.|| LEQYIYHKPKPNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEGKNYYTEKS EVWSLGVTLYFMLFFKLKDESIQEYDSHNICNTSYPWFANTNKLLKIAIKE--------------QQKVRFPED--VEVSEQVKQLIARMLVYDEKNRIS ..||||||||.||..||..|||||||||||||..|||..||.| ||..|.| .|...|||. ...|..|||||..||..||..||. DIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEEKRID TDELFNHELF .||.||||.. WDEIFNHECI |
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| Kinase | 20139.AA | Ciliate-E2 | 11-296 | 23 | 1.2e-92 | 314.16 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 11-296
Range on HMM: 1-365/365
Sequence Identity: 23% (95 aa)
FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQL---------FAIKMLQLNVF--KQYNISDPLERIMQEIE----------LQKDLDHPHITKYVD
.. ....|||. |.|||.. .. . . ..... |. ..||. .... .| .. ..||.||. ... |.||.| |...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE
AVK--TEQNVYIVTEFCNGGNLEQYIYNN------------RPKEQRVLFLFSQIIS---------------GFKYLMTEKNIIHRDIKPSNILIHDDIP
. . ...|.|.|.|.|.||.|..||.|| ...|. ..... ||.. ...|| ..|||||||||.|||. .
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----I
KICDFSISRKSNILND-------------------------------TYKTITGTPLFSSPQILKGKE---------YTSKSEVWSLGVTLYFMLFFKLK
||.|| .|.| .. |. ...|| ||| . .|.||.||. |. |. .|||||.||.||| |.
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP
DESIQEYDSHNICNTSYPWFANTNKLLKIAIKEQQKVRFP----------------EDVEVSEQVKQLIAR----MLVYDEKNRIS-TDELFNHELF
. ...|.|..|| . ..|...|.|| . ||..|...||. ....||. |
F---------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | 20139.AA | ULK | 11-216 | 34 | 1.1e-67 | 231.14 | In-house | 1-251 (329) | Show / Hide |
Range on Protein: 11-216
Range on HMM: 1-251/329
Sequence Identity: 34% (88 aa)
FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQLFAIKMLQLNVFKQYNISDP----LERIMQEIELQKDLD--------HPHITKYVDAVKTE--QN
.. |..||.|| |||||. . . | ..|...|.||.... ..| | .. .. ...||...| |. ||.| |. | .| |
YCLNHCLGKGSFGKVYKG----RNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNN
VYIVTEFCNGGNLEQYIYNNRP-----------KEQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIHDDIPK-------------ICDFSISRKSN
.||..|.||||.||||| .|.. || .. | ||..|||.| ..|||||||||.|||||...|| |.|| ... .
IYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKEL-HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVD
I---LNDTYKTIT------GTPLFSSPQILK----GKEYT-SKSEVWSLGVTLYFMLF
.. ..| . ||||. .||||. .|.|. .|. .||||. .| ||.
NDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLY
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| Kinase | 20139.AA | ULK | 11-216 | 34 | 4.7e-67 | 229.08 | In-house | 1-247 (324) | Show / Hide |
Range on Protein: 11-216 Range on HMM: 1-247/324 Sequence Identity: 34% (88 aa) FNENEILGQGSLG-KVYKA-NLVEEVNGEKKVVKQNQLFAIKMLQLNVFKQYNISDP----LERIMQEIELQKDLD---HPH--ITKYVDAVKTE--QNV .. |..||.|| | ||||. | . |||..|.|| ... ... . .. .. ...||...| |. ||. | |. | .| |. YCLNHCLGKGSFGVKVYKGRNKKTNT--------QNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNI YIVTEFCNGGNLEQYIYNNRP----------KEQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIHDDIPK-------------ICDFSISRKSNI- ||..|.||||.||||| .|.. || .. | ||..|||.| ..|||||||||.|||||...|| |.|| ... . YIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKEL-HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNN -LNDTY-KTIT------GTPLFSSPQILK----GKEYT-SKSEVWSLGVTLYFMLF .... .|. ||||. .||||. .|.|. .|. .||||. .| ||. NMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLY |
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| Kinase | 20139.AA | Ciliate-E2-Unclassified | 11-296 | 25 | 7.8e-67 | 228.35 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 11-296 Range on HMM: 1-352/352 Sequence Identity: 25% (95 aa) FNENEILGQGSLGKVYKANLVEE----------VNGEKKVVKQNQLFAIKMLQLNVFKQYN------ISDPLERIMQEIELQKDLDHPHITKYVDAVKTE .. ....|||. |||||. .. .. ..|. .... ..|.... .. . . ..|||. . ....||.| |.... ... YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKY----NKIMQQ--ILLNHPHPFIVKMFYCFQDK QNVYIVTEFCNGGNLEQYIYN------------------NRPKEQRVL-----FLFSQIISGFKYLMTEKNIIHRDIKPSNILIHDD----IPKICDFSI ||.|||.|.|.||.|.||| . .. || .. |.| ||..|..|| ..|||||||||.|||.... .||.||.| QNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGI SRKSNIL---------------NDTYKTITGTPLFS----SPQILKGKEYT----SKSEVWSLGVTLYFMLFFKL--KDESIQE---YDSHNICNTSYPW |.|.. .. ..|..||| . .| .|.|..| |. .||||| ||.||| .. .|.. . . . .| | SKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-N----- FAN-TNKLLKIAIKEQQKVRFPED-----VEVSEQVKQLIA----RMLVYDEKNRISTDELFNHELF | ..| |. ||... .... .|...| .| .||... ..||. ....|| .| --NAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | 20139.AA | S_TKc | 11-296 | 24 | 8.8e-64 | 219.13 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 11-296 Range on HMM: 1-231/231 Sequence Identity: 24% (76 aa) FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQLFAIKMLQLNVFKQYNISDPLERIMQEIELQKDLDHPHITKYVDAVKTEQNVYIVTEFCNG--GN . ...|.|. |||||. .. ....|||.. |.|..||.. | .||.| |. |. . ...|.|.|.|.| |. YEILRKIGKGAFGKVYKCRHKK----------TGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGD LEQYIYNNRP-------KEQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIHDDIPKICDFSISRKSNILNDTYKTITGTPLFSSPQILKGKEYTS- | .|| .... | .. |.. ||... .|. .|||||.||.|||. . ||||| ..|. .|. ||| . .| .| |. LFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKC KSEVWSLGVTLYFMLF----FKLKDESIQEYDSHNICNTSYPWFANTNKLLKIAIKEQQKVRFPEDVEVSEQVKQLIARMLVYDEKNRISTDELFN---- |. .||.|..|| || | |.. ... |...|..| ..|..| ..|.. |... KCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD ---HELF |. | IKCHPWF |
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| Kinase | 20139.AA | Pkinase | 11-296 | 23 | 1.4e-55 | 195.72 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 11-296 Range on HMM: 1-293/293 Sequence Identity: 23% (78 aa) FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQLFAIKMLQLNVFKQYNISDPLERIMQEIELQKDLDHPHITKYVDAVKTEQNVYIVTEFCNGG--- . ...|.|| |.|||. . . ..|.| . . . . . |. .||.. | |.||.| .. |.. .....|.|.|.|.|| YHIGRKIGSGSFGCVYKCHHKGTGK----------IVAVKIIKKR-HEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYV -NLEQYIY---NNRP--KEQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIH-DDIP----KICDFSISRKS-NILNDTYKTITGTPLFSSPQILK- | || ... |. . | . ||..| .|. ..|||||.||.||||. .. . ||||| .... . | ..|..||| . .| ... MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG GKEYTSKSEVWSLGVTLYFMLFFKLKDESIQEYDSHNICNTSYPWFAN-----TNKLLKIAIKEQQKVRFPEDVEVS-------------------EQVK |..|..|. .||.|..|| ||. . |. ... .|. . . ...|... . | | | GQYYGPKVDMWSCGCILYEMLCGR------------------PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECK QLIARMLVYDEKNRISTDELFNHELF ..| ..| .| | |.. .....|. | DFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 20139.AA | CAMK | 16-296 | 19 | 6.1e-54 | 171.83 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 16-296
Range on HMM: 1-425/425
Sequence Identity: 19% (87 aa)
ILGQGSLGKVYKANLVEEV-NGEKK-----VVKQNQLFAIKMLQ-----------------LNVFKQYN-----ISDPLERIMQEIELQKD-------LD
.||.|| |||. |... .. |. .. .| .|||.. .. |. . ......|||. | ||
TLGRGSFGKVK---LCIHKNTTGKERVHHIYTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLD
HPHITKYVDAVK------------TEQN--------VYIVT---EFCNGG----NLEQYIYNNRP----------------KEQRVLFLFSQIISGFKYL
||.| | .. | .. .|.|. |.| || | .|| ... .|. . ..| ||.|. .|.
HPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYC
MTEKNIIHRDIKPSNILIHDD------------------IPKICDFSISRKSNIL-----------------------NDTYKTITGTPLFSS-PQILKG
. |.|||.|| |||. |. ||.|| ..| . .. .|| ||| . . | .|.|
HSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG
KE--------------YTSKSEVWSLGVTLYFMLFFKLKDESIQEYDSHNICNTSYPWFAN-------------TNKLLKIAIKEQQKVRFPEDVE----
| |. |. .||.|| ||.| .|. . . . |. |.. . |. .
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIM------------------LCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISC
---------VSEQ--------VKQLIARMLVYDEKNRISTDELFNHELF
.|.. .|.|| .||..| ..|.. .. ||. .
NYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 20139.AA | CAMKL | 11-296 | 26 | 4.6e-51 | 161.11 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 11-296 Range on HMM: 1-297/297 Sequence Identity: 26% (86 aa) FNENEILGQGSLGKVYKANL-VEEVNGEKKVVKQNQLFAIKMLQ-----LNVFKQYN------ISDPLERIMQEIELQKDLD---HPHITKYVDAVKTEQ .. . ||.|| ||| | .. |||.. .. ... | ||. || .||...| |. ||.| | . . |.. YRIGKTLGKGSFGKVKLATHIRTT----------GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM--RIRREIQIMKMLNIGKHPNIIKLYEVIETPE N------VYIVTEFCNGGN--LEQYIYNN-----RPKEQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIH-DD--IPKICDFSISRKSNIL----N . .|.|.| | ||. | .|| .. | .| ..| ||.|. .| . ...|.|||||| |||. .. ||.|| | . . HDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNY-CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPG DTYKTITGTPLFSSPQILKG--KEYT-SKSEVWSLGVTLYFMLFFKL--KDESIQEYDSHNICNTSYPWFANTNKLLKIAIKEQQKVRFPEDVEVSEQVK .. || |.| . .| |..| |.| | .||.||.||.|.. .| .|..... ..|. .. .. .. ..| ..|| ... QKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNK-------------QGKDNI-YLYWKIMCG-YYPPIWYHVS-DCR QLIARMLVYDEKNRISTDELFNHELF .|| .||. . . |.. ... ||. . DLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 20139.AA | Ciliate-E2b | 11-216 | 29 | 7.8e-47 | 140.43 | In-house | 1-205 (272) | Show / Hide |
Range on Protein: 11-216 Range on HMM: 1-205/272 Sequence Identity: 29% (65 aa) FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQLFAIKMLQLNVFKQYNISDPLERIMQEIELQKDLDHPHITKYVDAVKTEQNVYIVTEFCNGGNLE . . ||.| | || || . ...|..|.| . | | |. . ..||... . ..|| | |.... |..|..| . |||||. |. MIYIKKLGFGQFGSVY---LVWNT------KNTKQYYAMKCISKNQIIQQNMEK---HMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELF QYIYNNR---PKEQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIHD-DIPKICDF----SISRKSNILNDTYKTITGTPLFSSPQILK-----GKE .| . .. ..| . .|. ...|| ..|||.|||||.||... .|. |. .. |. ... |. || ||| . |.|.. || DVIREIGRLLLSTYDSQFYIASICLCLEYLH-NQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTF-TIIGTPHYMAPEIIQSLQPGGKG YTSKSEVWSLGVTLYFMLF || |. .||.|..||.... YTYKVDIWSVGICLYEFMC |
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| Kinase | 20139.AA | STE | 12-215 | 24 | 4.6e-46 | 159.36 | In-house | 1-262 (359) | Show / Hide |
Range on Protein: 12-215 Range on HMM: 1-262/359 Sequence Identity: 24% (65 aa) NEN-EILGQGSLGKVYKANLVEEVNGEKKVVKQ------NQLFAIKMLQLNVFKQYNIS------------DPLERIMQEIELQKDLD--HPHITKYVDA |. |..|.|. |.|||| .. |.. | .. ....||| . |. .... . . ...|..||.. |... ||.| || .. WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC VKTE-------QNVYIVTEFCNGGNLEQYIYNNRPK---------------EQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIHDDIPKICDFSIS | ....|. |...|| |.. | .. . |. . . ||. |. |. ...||||||||.|||. |.||| .. YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVC RKSNILND----------------TYKTITGTPLFSSPQILKG------KEYTSKSEVWSLGVTLYFML . . .. .|..||| . .| .... |.|. |. .|||| |. |. GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA |
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| Kinase | 20139.AA | NEK | 11-212 | 32 | 1.1e-34 | 119.74 | In-house | 1-215 (286) | Show / Hide |
Range on Protein: 11-212 Range on HMM: 1-215/286 Sequence Identity: 32% (73 aa) FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQLFAIKMLQLNVFKQYNISDPLERIMQEIELQKDLDHPHITKYVDAVKTEQ--NVYIVTEFCN-GG . . . .|||| ||||| |. . .|..| .|...| ... .. . . . .|. . | |.||.| || |. || .|| |.|. || YEIIKKIGQGSFGKVYK---VRRKSDGKHLV--EKLYVWKKINMGNMSEKEKQNAQN---NEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGG NLEQY---IYNN-----RPKEQRVLFLFSQIISGFKYLMTEK----NIIHRDIKPSNILIHDD-----IPKICDFSISRKSNILNDTYKT-ITGTPLFSS .|.| | .. | .. | |.... ||. .| .|.||||||.|| . .. . || || ||. | .| .| .||| . | DLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMS PQILKGKEYTSKSEVWSLGVTLY | ....| |..|| .||||. || PEVCQNKPYNNKSDIWSLGCVLY |
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| Kinase | 20139.AA | ULK | 237-296 | 38 | 8.9e-18 | 58.7 | In-house | 254-329 (329) | Show / Hide |
Range on Protein: 237-296 Range on HMM: 254-329/329 Sequence Identity: 38% (29 aa) YPWFAN-TNKLLKIAIKE------------QQKVRFP---EDVEVSEQVKQLIARMLVYDEKNRISTDELFNHELF .|..|. . |.| .|. .|. .|| .|. .|...|.|| |||.|||| ||| .|||||..| PPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 20139.AA | ULK | 237-296 | 36 | 6.2e-17 | 56.66 | In-house | 250-324 (324) | Show / Hide |
Range on Protein: 237-296 Range on HMM: 250-324/324 Sequence Identity: 36% (28 aa) YPWFAN-TNKLLKIAIKE------------QQKVRFP---EDVEVSEQVKQLIARMLVYDEKNRISTDELFNHELF ||.|.. .. |. .|. .|...|| .|. .|...|.|| |||.|||| ||| .|.|||..| YPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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| Kinase | 20139.AA | TyrKc | 11-296 | 21 | 2.7e-15 | 24.48 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 11-296 Range on HMM: 1-280/280 Sequence Identity: 21% (70 aa) FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQLFAIKMLQLNVFKQYNISDPLERIMQEIELQKDL--DHPHITKYVDAVKTE-------QNVYIVT ...|| | |.|||. . . |.|||. . .| .|.|... . | .||.| . . .. .. . ..||. ITLGKKLGEGAFGEVYKGTWK-------------IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM EFCNGGNLEQYIYNNR--PKEQRVLFLFSQIISGFKYLMTEKNIIHRDIKPSNILIHDD-IPKICDFSISRKSNIL------NDTYKT----ITG--TPL |.. .|.| .|. ..| . . | || .| || .||.||||. |.|.... . ||.|| ||. |.|.. . |. EYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYL-HSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI F-SSPQILKGKEYTSKSEVWSLGVTLYFMLFFKLKDESIQEYDSHNICNTSYPWFA---NTNKLLKIAIKEQQKVRFPED------VEVSEQVKQLIARM .| .. ...|.|| ||| ||... .. . . . || . .|. . .|. . |.. |. .. . |.. . RWMAPECINYGKFTTKSDVWSFGVCMWEIFTY---------------GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQC LVYDEKNRISTDELFNHELF .| ..| . |. ||.| WHEDPEDRPTFSEI--HECF |
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| Kinase | 20139.AA | Pkinase_Tyr | 11-117 | 23 | 7.5e-11 | 37.37 | Pfam | 1-102 (270) | Show / Hide |
Range on Protein: 11-117 Range on HMM: 1-102/270 Sequence Identity: 23% (27 aa) FNENEILGQGSLGKVYKANLVEEVNGEKKVVKQNQLFAIKMLQLNVFKQYNISDP---LERIMQEIELQKDL-DHPHITKYVDAVK-TEQN--VYIVTEF .. ||.|. |.|||. . . .... |.||| . . ... .| |.|... | | .||.| ... .. .. .|||.|. ITFGKKLGEGAFGEVYKGTWKG------DPDNTKIPVAVKML-KE-----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY CNGGNLEQYIYNNR . .|.| | ..| MPHGDLLDYLRKHR |
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| Kinase | 20139.AA | STE | 237-296 | 11 | 1e-05 | 16.38 | In-house | 266-359 (359) | Show / Hide |
Range on Protein: 237-296 Range on HMM: 266-359/359 Sequence Identity: 11% (11 aa) YPWFA-NTNKLLKIAIKE--------------QQKVRFPEDVE-----------------VSEQVKQLIARMLVYDEKNRISTDELFN--HELF .||. . . . .... .. ..|.... .|. |. |.. |..| ..| ....| . |. . PPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | 20139.AA | NEK | 266-296 | 25 | 7.4e-05 | 13.48 | In-house | 256-286 (286) | Show / Hide |
Range on Protein: 266-296 Range on HMM: 256-286/286 Sequence Identity: 25% (8 aa) SEQVKQLIARMLVYDEKNRISTDELFNHELF |.. ..|| .|| | ..| |....... . SQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | 20139.AA | Pkinase_Tyr | 140-186 | 36 | 0.200145 | 5.45 | Pfam | 129-176 (270) | Show / Hide |
Range on Protein: 140-186 Range on HMM: 129-176/270 Sequence Identity: 36% (18 aa) EKNIIHRDIKPSNILIH-DDIPKICDFSISRKSNILNDTY-KTITGTPL .||.||||. |.|.. . . ||||| .| |.| .. .|..| SKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKL |
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| Kinase | 20139.AA | Pkinase_Tyr | 193-212 | 40 | 0.237225 | 5.2 | Pfam | 186-205 (270) | Show / Hide |
Range on Protein: 193-212 Range on HMM: 186-205/270 Sequence Identity: 40% (8 aa) LKGKEYTSKSEVWSLGVTLY .. ...|.|| ||| ||... INYGKFTTKSDVWSFGVLMW |
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