Gene 5330 (Tetrahymena)
5330
Sequence
Protein domains of 5330.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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CNMP_binding | 5330.AA | cNMP_binding | 214-292 | 34 | 3.7e-16 | 58.09 | Pfam | 8-91 (91) | Show / Hide |
Range on Protein: 214-292 Range on HMM: 8-91/91 Sequence Identity: 34% (29 aa) EYIFKQGDAASTYFIIEKGECFVEINGEVKK-----KLNMGDAFGELALLYGA-PRSASVKADGICGLWGIDRSTFRKAVEEIVR |.||.|||... .|...|.. |. .| . | || |||.||... ||.|.|.| . | .| |.|..||. ... EVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQNPRTATVVALTDCECWRIPREDFRQLMQQHPE |
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CNMP | 5330.AA | cNMP | 190-302 | 27 | 9.3e-13 | 49.63 | SMART | 1-123 (123) | Show / Hide |
Range on Protein: 190-302 Range on HMM: 1-123/123 Sequence Identity: 27% (34 aa) VFSLLNEVNRDKVIGKMFY-CENSEEYIFKQGDAASTYFIIEKGECFVEIN---------GEVKKKLNMGDAFGELALLYGAPRSASVKAD-GICGLWGI .|. |.| . ... .|. ||||.|||.... .||..|. | . . . |. || ||||||| .||.|...| | .| | MFKNLDEQELRELCDHMEPRHYPAGEYIFRQGDPGDHFYIIVSGWVRVYKTRVQHMEDGREQIVGFLGPGDFFGELALL-RRPRTAAARACCECCTIWRI DRSTFRKAVEEIVRTEFEENRNFI |. |. ..... . .. .... DFQHFMQQLQQHPQHMYRMLQQLA |
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CNMP_binding | 5330.AA | cNMP_binding | 325-413 | 29 | 1e-20 | 73.78 | Pfam | 1-91 (91) | Show / Hide |
Range on Protein: 325-413 Range on HMM: 1-91/91 Sequence Identity: 29% (27 aa) TQVFKKGDCIVNEGDMASSYYIIKKGKVGIFQGNNEKP---IRTMGPEDSFGEQALYENS-KRGATVKALDDEVRCIALGRDTIQKVLGDKIQ .. .|||. |. .|| ... ||...||| ... . . ....|| | ||| || .|. .| |||.| ....|... |....... . . VRHYKKGEVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQNPRTATVVA-LTDCECWRIPREDFRQLMQQHPE |
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CNMP | 5330.AA | cNMP | 307-423 | 19 | 3e-15 | 57.9 | SMART | 1-123 (123) | Show / Hide |
Range on Protein: 307-423 Range on HMM: 1-123/123 Sequence Identity: 19% (24 aa) FFTTMTTAQKDAITNVLITQVFKKGDCIVNEGDMASSYYIIKKGKVGIFQG-------NNEKPIRTMGPEDSFGEQALYENSKRGATVKALDDEVRCIAL .|.... .. .. ... ......|..|. .|| ... ||| .|.| ... .|. ....|| |.||| || .. | |...|. ... . MFKNLDEQELRELCDHMEPRHYPAGEYIFRQGDPGDHFYIIVSGWVRVYKTRVQHMEDGREQIVGFLGPGDFFGELALL-RRPRTAAARACCECCTIWRI GRDTIQKVLGDKIQVVMYNNVMRW .. .. |.. | ... . DFQHFMQQLQQHPQHMYRMLQQLA |
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CNMP_binding | 5330.AA | cNMP_binding | 448-534 | 20 | 0.001437 | 14.84 | Pfam | 1-91 (91) | Show / Hide |
Range on Protein: 448-534 Range on HMM: 1-91/91 Sequence Identity: 20% (19 aa) QIQYKKGDLIFKKEQPCKKLIFVLES--CLVNKSNQKK-----VVDKGHAFGEQWLFEQNKNKVLDDDLIMEDKGLLGEISHEQLVECIGGPIE ..||||. ||.. .|| . .||. .. . . . .. .| ||| ||... . . .. . .|..|.. ... | VRHYKKGEVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQ--NPRTATVVALTDCECWRIPREDFRQLMQQHPE |
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Kinase | 5330.AA | Ciliate-E2b | 568-825 | 65 | 2.2e-202 | 620.47 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-272/272 Sequence Identity: 65% (178 aa) MIYIKKLGFGQFGSVYLVKN-KHDSQFYALKVIQKAQVIQQNLEKHLIQEKKVLEVAQFPFMMKFIKTFKDNQNVYFLLEYVKGMELFDVIREIG--LLN ||||||||||||||||||.| |...|.||.|.|.|.|.||||.|||..|||.|||....||.||||..|||.|..||..|...|||||||||||| ||. MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS TYDSQFYIASLLLNIEYLHTNSIIYRDIKPENIIIDYKGYMKLIDMGTAKFLKGSSG---KTFTIIGTPHYMAPEILT-----GAGYTYSVDLWSIGICL ||||||||||..|..||||...|||||||||||..|.|||||||||||||....... .|||||||||||||||.. | ||||.||.||.|||| TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL YEFMCGGVPFAEDVEDPYEIYEDIIHK--NLDFPSFLKDKLA-KNIMNQLLNKQPQLRLGGSFAALKANQWF ||||||.||.||||.||||||..||.| ...|||..|||.| |..|.|.|.|.|..|||||...||...|| YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF |
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Kinase | 5330.AA | AGC | 568-825 | 24 | 1.1e-104 | 271.0 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-395/395 Sequence Identity: 24% (98 aa) MIYIKKLGFGQFGSVYLVKNKH-----DS-QFYALKVIQKAQ-VIQQN--LEKHLIQE------------KKVLEVAQ----------FPFMMK-FIKTF .| .| | || ||||. |. |. ..||.||..|. ... . ..| . | ...|| .. || | .| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF KDNQN--VYFLLEYVK----------GMELFDVIR---EIGLLNTYDSQFYIAS-------LLLNIEYLHT-NSIIYRD-IKPENIIIDYKGYMKLIDMG .|... .||..||.. |.||| .. | .. ..||.| ..| .|||| . ||.|| .||||| .| .|. || | | QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG TAKFLKGSS--------------------------------------------------GKTFTIIG--TPHYMAPEILTGAGYTYSVDLWS--IGICLY .| .... .| |. | ||.||||||| |....| || |...| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EFMCGGVPFAE-DVE-------DPYEIYEDII------HKNLDFP----------SFLKDKLAKNIMNQLLNKQPQLRLG--GS------FAALKANQWF |...| || ... .|.|... |. .... || ... .. ||.....||.| | ||| |. . .|. || EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWF-SPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 5330.AA | Ciliate-E2 | 568-825 | 26 | 1.4e-90 | 307.27 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-365/365 Sequence Identity: 26% (101 aa) MIYIKKLGFGQFGSVYLVKN-----------------------KHDSQFYALKVIQKAQVIQQNLEKHLI----------QEKKVLEVAQFPFMMKFIKT . |||.|.|.|||||..|. | ....||.|...| |..|.. |.|.. .||..|| ..|. .|.. . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FK--DNQNVYFLLEYVKGMELFD-------------------VIREIGLLNTYDSQ-------FYIASLLLNIEYLHTNS-IIYRDIKPENIIIDYKGYM |. |..|.|. .||..|..||| ...||. . .. | ||||...| .|||| . ||.||||||||.. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLIDMGTAKFLKGSSG-------------------------------KTFTIIGTPHYMAPEILTGAG---------YTYSVDLWSIGICLYEFMCGGVP |.||.|..|... .. ..||.|||.||||||| | . |.|..|.||.|..|||...| | KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FAEDVEDPYEIYEDIIHK-NLDFP----------------SFLKDKLA-KNIMNQ----LLNKQPQLRLGGSFAALKANQWF | ...|.. ..||| |..| . |..... .|.|.|. |.. .. .. ..|| F-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT-GWEQILNHPWF |
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Kinase | 5330.AA | PKA | 568-825 | 36 | 1.6e-78 | 267.22 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-263/263 Sequence Identity: 36% (97 aa) MIYIKKLGFGQFGSVYLVKNKHDSQFYALKVIQKAQVIQQNLEKHLIQEKKVLEVAQFPFMM-KFIKTFKDNQNVYFLLEYVKGMELFDVIREIGLLNTY |. || | || |.|...||. ..||.|.. |..... . . | . ||..| ..|| | . ||.|... |...||| | |.|. .| | .. . FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP DSQFYIA-SLLLNIEYLHTNSIIYRDIKPENIIIDYKGYMKLIDMGTAKFLKGSSGKTFTIIGTPHYMAPEILTGA-GYTYSVDLWSIGICLYEFMCGGV ...||.| | .||||. ||||| ||||| || .|. |. | | || ... |.|. ||| |.||||... |. ||| |. || ||.. | HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP PFAEDVEDPYEIYEDIIHKNLDFPSFLKDKL--AKNIMNQLLNKQPQLRLGGSFA---ALKANQWF || .. || .||| |. ..||... .. | ..||.. . |.| . | || PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | 5330.AA | S_TKc | 568-825 | 29 | 3.1e-73 | 250.51 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-231/231 Sequence Identity: 29% (81 aa) MIYIKKLGFGQFGSVYLVKNKHDSQFYALKVIQKAQVIQQNLEKHLIQEKKVLEVAQFPFMMKFIKTFKDNQNVYFLLEYVKG--MELFDVIREIGL--- ..|.| | ||.||....|.. . .|.|.| .|...| ..|. . |. |.. .| | ...|. .||. | .|||.|.. | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LNTYDSQFYIASLLLNIEYLHTNSIIYRDIKPENIIIDYKGYMKLIDMGTAKFLKGSSGKTFTIIGTPHYMAPEILTGAGYTY-SVDLWSIGICLYE .. . .||.. ... .||.| . ||.||.||||| .| |..| | |..| |..|||.|||||.| ||.. ..| ||.|..||| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE FMCGGVPFAEDVEDPYEIYEDIIHKNLDFPSFLKDKLAKNIMNQLLNKQPQLRLGGSFAAL-----KANQWF ..|| || ....... | .. ||......|.| |. |.. | |. .|| MLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 5330.AA | AktR | 569-825 | 35 | 6.3e-68 | 231.98 | In-house | 2-268 (268) | Show / Hide |
Range on Protein: 569-825 Range on HMM: 2-268/268 Sequence Identity: 35% (95 aa) IYIKKLGFGQFGSVYLVKNK-HDSQFYALKVIQKAQVIQQNLEKHLIQEKKVLE-VAQFPFMMKFIKTFKDNQNVYFLLEYVKGMELFDVIREIGLLNTY ..| || | || ||||. | . ..||.|.| | |..|...|.|.|....| ...||. |. ..|... . .|..||..| |||.... .. .. HVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEE DSQFYIASLLLNIEYLHTN-SIIYRDIKPENIIIDYKGYMKLIDMGTAK--FLKGSSGKTFTIIGTPHYMAPEILTG-AGYTYSVDLWSIGICLYEFMCG ...||.| || .|||| . |||||.||||| .| |. |..| | .| | . . |. .. |||.|||||..| |...|||.|..|| .|| . | QARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTG GVPFAEDVEDPYEIYEDIIHKNLDFPSFLKD-KLAKNIMN-QLLNKQPQLRLG-G--SFAALKANQWF || . ....|. .. || . . .|.. . .||.| |. ||| . .. .| || CPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | 5330.AA | SGK | 569-825 | 32 | 8.2e-67 | 205.2 | In-house | 2-283 (283) | Show / Hide |
Range on Protein: 569-825 Range on HMM: 2-283/283 Sequence Identity: 32% (94 aa) IYIKKLGFGQFGSVYLVKNKHD------------------SQFYALKVIQKAQVI-------QQNLEKHLIQEK-KVLEVAQFPFMMKFIKTFKDNQNVY ...|..| | || ||.|| | | .|||.||.||...| . ...|| |. ..| || . | . | DFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKLY FLLEYVKGMELFDVIREIGLLNTYDSQFYIASLLLNIEYLHTNSIIYRDIKPENIIIDYKGYMKLIDMGTAKFLKGSSGKTFTIIGTPHYMAPEILTGAG | ..|| | |.| .. . . . || | . . .|||| ||||| ||||| | .|. .| | | .| . .|||. ||| |.|||.| ... FVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQP YTYSVDLWSIGICLYEFMCGGVPFAEDVEDPYEIYEDIIHKNLDFPSFLKDKLAKNIMNQLLNKQPQLRLGGS--FAALKANQWF . .|| |..|. |||.| | || . . |. ||.. | .| . . |. ....||.| |. ||| |. | ..| HDRTVDWWCLGCVLYEMMYGLPPFYS--RNKQQMYDNIINQPLQIPPQMSND-AWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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Kinase | 5330.AA | RSK | 571-825 | 31 | 1.3e-66 | 227.64 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 571-825 Range on HMM: 1-278/278 Sequence Identity: 31% (89 aa) IKKLGFGQFGSVYLVKNK---HDSQFYALKVIQKAQVIQQNL-EKHLIQEKKVLEVAQ-FPFMMKFIKTFKDNQNVYFLLEYVKGMELFDVIREIGL--- .| || | .|.|.|.. . | || ||..|| ..| . .| .| ..|| | || . .|.... .| .||..| |||. ... . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LNTYDSQFYIASLLLNIEYLHTNSIIYRDIKPENIIIDY---KGYMKLIDMGTAKFLKGS-SGKTFTIIGTPHYMAPEILT----GAGYTYSVDLWSIGI . . .||.| . | .|.||. ||.||.|||||. | | ||.| | .| .. . ...| | ..| .|||||.|. . |.. ..|.|| |. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV CLYEFMCGGVPFAE--DVEDPYEIYEDIIHKN--LDFP--SFLKDKLAKNIMNQLLNKQPQLRLG---GSFAALKANQWF .|| | .||. | ... || . | ... |..| ..| . ||.. ...| . |. ||| . . .|...|| LMYEMLTGCPPFQGPND-NNRKEIMKRIQKGKFSLTMPNWQYL-SQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 5330.AA | Pkinase | 568-825 | 27 | 1.3e-62 | 219.14 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-293/293 Sequence Identity: 27% (83 aa) MIYIKKLGFGQFGSVYLVKNKHDSQFYALKVIQKAQVIQQNLEKHLI-QEKKVLEVAQFPFMMKFIKTFKDNQNVYFLLEYVKGM----ELFDVIR--EI ..|.| | ||.||. ..| ... .|.|.| | . .. |. .| ... . |. ... .| |....|. .||. | .|||.|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GLL--NTYDSQFYIASLLLNIEYLHTNSIIYRDIKPENIIIDYKGYM----KLIDMGTAKFL-KGSSGKTFTIIGTPHYMAPEILT-GAGYTYSVDLWSI | . . .||. .| .||.| ..||.||.||||| || .|. |..| | ||.. ... . |. |||.|||||.. | .|...|| ||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GICLYEFMCGGVPFA-E----DVEDPYEIYEDIIHKNLDFPSFLKD--------------------KLAKNIMNQLLNKQPQLRLGGSFAALKANQWF |. |||..|| || . . |...... | .. |.|... .. . .| ... .|.| |. |.. .. .. || GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--AEQILQHPWF |
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Kinase | 5330.AA | Ciliate-E2-Unclassified | 569-825 | 28 | 4.9e-62 | 212.42 | In-house | 2-352 (352) | Show / Hide |
Range on Protein: 569-825 Range on HMM: 2-352/352 Sequence Identity: 28% (99 aa) IYIKKLGFGQFGSVYLVKNKHDSQFYALKVIQKAQVIQQNLEKHL---------IQEKK-------------VLEVAQFPFMMKFIKTFKDNQNVYFLLE . ||..| |.||.||....| . |.||.| . |.|.. |.. .. ...|| | . || .|.. .|.| ||.|. .| KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVME YVKGMELFDVIREI-----------------GLLNTYDSQ-----FYIASLLLNIEYLHTNS-IIYRDIKPENIIIDYKG---YMKLIDMGTAKFLKGSS |..| .|.. |.. . . .. ||.| .|. .|||| . ||.||||||||..| .| | |.|| | .|... .. YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN GK---------------TFTIIGTPHYM----APEILTGAGYT----YSVDLWSIGICLYEFMCGGVPF-AEDVEDPY-------------EIYEDIIHK .. . |..||| || |||.| | .| |..| || |..|||.. | || ... |. . ..|..|. | NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQK NLDFPSFLK-------DKLAKNIMN----QLLNKQPQLRLGGSFAALKANQWF |..||.| . .. ||.. | ..|.|.| |. .| .. .|| NIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI--TFEQILNHPWF |
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Kinase | 5330.AA | PKG | 568-825 | 35 | 8.4e-61 | 208.32 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-260/260 Sequence Identity: 35% (94 aa) MIYIKKLGFGQFGSVYLVKNKHD-SQFYALKVIQKAQVIQQNLEKHLIQEKKVLEVAQFPFMMKFIKTFKDNQNVYFLLEYVKGMELFDVIREIGLLNTY . | || | || | ||. .|. |. .|||...|.... . . | . ||.... .. .| . .||.|. ||.|.| | || ..|. | . LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK DSQFYIASLLLNIEYLHTNSIIYRDIKPENIIIDYKGYMKLIDMGTAKFLKGSSGKTFTIIGTPHYMAPEILTGAGYTYSVDLWSIGICLYEFMCGGVPF ..||.| . .||| ||||| ||||.. | .||.||.| | ||.. |...|| | ||| | |||| | ||| |. || .| . | || TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKI-GQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPF AEDVEDPYEIYEDIIH--KNLDFPSFLKDKLAKNIMNQLLNKQPQLRLGGS---FAALKANQWF || .| | ..||.. . |.|.. .| .| ||| . | .|| S--GSDPMKTYNIILKGIDMWEFPRKIT-RWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF |
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Kinase | 5330.AA | Delta | 568-825 | 31 | 3.2e-57 | 196.42 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-259/259 Sequence Identity: 31% (82 aa) MIYIKKLGFGQFGSVYLVKNKHDSQFYALKVIQKAQVIQQNLEKHLIQEKKVLEVA-QFPFMMKFIKTFKDNQNVYFLLEYVKGMELFDVIREIGLLNTY .. | || | || | |. |. ..||.| ..| |.. . |..|| .| . ||. ... ||. .....| .||. | .| | ... . . FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK DSQFYIASLLLNIEYLHTNSIIYRDIKPENIIIDYKGYMKLIDMGTAKFLKGSSGKTFTIIGTPHYMAPEILTGAGYTYSVDLWSIGICLYEFMCGGVPF ..|| . ... ...||.. |||||.| .|...|. | .|. | | .| .|. | ||| |.||||. | |. ||| || |. .|| . | || RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF AEDVEDPYEIYEDIIHKNLDFPSFLKDKLAKNIMNQLLNKQPQLRLGG---SFAALKANQWF . || |... |.. . .| ... | ||.....|....|. ||| ... ..| HGEDED--ELFWSICNDRPWYPRWIT-KEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF |
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Kinase | 5330.AA | TyrKc | 568-825 | 19 | 2.7e-11 | -39.97 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 568-825 Range on HMM: 1-280/280 Sequence Identity: 19% (58 aa) MIYIKKLGFGQFGSVYLVKNKHDSQFYALKVIQKAQVIQQNLEKHLIQEKKVLEVA--QFPFMMKFIKTFKDN-------QNVYFLLEYVKGMELFDVIR .|||| |.|| ||. . | . | |.... .. ...| ... . | ... . . .. ..||... | | .| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR EIGLLNTYDSQFYIASLLLNI----EYLHTNSIIYRDIKPENIIIDYKGYMKLIDMGTAKFLKGS-----SGKTFTI---IGTP-----HYMAPEILTGA . . . | . | |||| . .| ||. |. .. .. .| | | ..... |... . |. |||| . KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG GYTYSVDLWSIGICLYE-FMCGGVPFAEDVE---DPYEIYEDIIHKNLDFPSFL---------KDKLAKNIMNQLLNKQPQLRLGGSFAALKANQWF .| | || |.|..| | |. | .... ...|..|.. . . . |.. . || | . .| | .|... . | KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRP--TFSEI--HECF |