Gene 27560 (Tetrahymena)
27560
Sequence
Protein domains of 27560.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 27560.AA | Ciliate-E2a | 1-265 | 47 | 3.7e-153 | 454.14 | In-house | 6-275 (275) | Show / Hide |
Range on Protein: 1-265 Range on HMM: 6-275/275 Sequence Identity: 47% (129 aa) MIGKGGFSRVFLAQDKFSRENYAIKVITKDKLLQQTKGIKSLLNEIQIMKELDNVNGCLKLIGVYETDSSVNLILEYIKGGELVKKIKLKDKQNFTIENM .|||| | .|.||| | ...|.|.. | |. ||.|| ... |||.||..||. | ..||..|||.... |..||..|||| .||| ...... |... KIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPN-IIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEI RQLMQNIL-IALAHIHQRKIIHRDLKPDNILIED-DINS---TKIKIADFGLATYDSTVLNDFLFKKCGTPGFLAPEVLSNKD--THKLYDHKVDVFSAG ...||..| .|...|||.|.||||||.|||... . || ..|||.||||||. .. ....|.||||||..||||| ||. .|| ||.|.|..|.| CDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCG VIFYILLCGQQPFKGSNHRQVVEQNKKCEIDFQILDSNQKIPQAAKILVKQMLAKDPINRPTSQECLNSPFF |||||||||..|||| .......|||||.|||.. .. .|.....| |.|.|| |||..|.| |..||.|.| VIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 27560.AA | CAMK1 | 1-265 | 40 | 1.7e-93 | 272.12 | In-house | 6-276 (276) | Show / Hide |
Range on Protein: 1-265 Range on HMM: 6-276/276 Sequence Identity: 40% (114 aa) MIGKGGFSRVFLAQDKFS---RENYAIKVIT-KDKLLQ---QTKGIKSLLNEIQIMK---ELDNVNGCLKLIGVYETDSSVNLILEYIKGGELVKKIKLK .||.| || |.|...| . ..||||.| |. . . | | ..|.|||.||| ..| | . |.. .||.|. . |..|...|||| .| | EIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ-K-QEALENEIEIMKKVSKIDHPN-IIKFYEWYESDNHFYLVMELVTGGELFDRIVEK DKQNFTIENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIEDDINSTKIK--IADFGLATYDSTVLND--FLFKKCGTPGFLAPEVLSNKDTHKLYDHK . |.| .. | .|..|| |. ..|.. | |||||| |.| .| . ||| ||||||... . .| .... |||||. ||||| .| | || . G--NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKI---FDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKA VDVFSAGVIFYILLCGQQPFKGSN-HRQVVEQNKKCEIDFQILDSN--QKIPQA-AKILVKQMLAKDPINRPTSQECLNSPFF .|..|.|||.|||||| .|| ..| . . |..||||..| .|. .| || ..|.|| .|| .|.| ..||| |.. CDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEF---PSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 27560.AA | Ciliate-E2 | 1-265 | 27 | 3.3e-88 | 299.34 | In-house | 6-365 (365) | Show / Hide |
Range on Protein: 1-265 Range on HMM: 6-365/365 Sequence Identity: 27% (103 aa) MIGKGGFSRVFLAQDKFSRENYAIKVITKDKLLQQT------------------KGIKSLLNEIQIMKELD---------------NVNGCLKLIGVYE- .||.|.|. |...... ....|||.|. .|. |.. ..|.....||.||.|.. | . .|.. ... KIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQE -TDSSVNLILEYIKGGELVKKIKLKDKQ---------NFTIENMRQLMQNIL---------------IALAHIHQRK-IIHRDLKPDNILIEDDINSTKI .|... |..||..||.| . || ..|. .||.. ....|. || || ..|... |||||.||.|||. | KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------I KIADFGLATYDSTVLN---------DFLFKK----------------------CGTPGFLAPEVLSNKD-----THKLYDHKVDVFSAGVIFYILLCGQQ ||.||||... .. . ..| | |||||..|||.|..|. ..| ||.|.|..|.|||.|..|.|. KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PFKGSNHRQVVEQNKKCEIDFQILD-------------SNQKIPQAAKILVKQ----MLAKDPINRPT-SQECLNSPFF || .|.|.|.|||. . |..|..| .| | |. || ||| .|.| ...|| |.| PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 27560.AA | CAMK | 1-265 | 23 | 5.7e-86 | 276.92 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 1-265
Range on HMM: 1-425/425
Sequence Identity: 23% (102 aa)
MIGKGGFSRVFLAQDKFSR------------ENYAIKVITKDKLLQ------------------------QTKGIKSLLNEIQIMKELD------NVNGC
.|.|.|. |.|...| . . .|||.| |.|| . | |....||.||| | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
LKLIGVYE------------TDSS--------VNLIL---EYIKGGEL----VKKIKLKDK-------------QNFTIENMRQLMQNILIALAHIHQRK
.||. ||| | | . ... ||. |||| .|. . . || . |.... |. |....|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IIHRDLKPDNILIEDDINST--------------KIKIADFGLATY----------------------DSTVLNDFLFKKCGTPGFLA-PEVLSNKDT--
|.||||||.|||. |. ... .|||.|||.|.. ... .. . ||||.. | ||||. | .
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------HKLYDHKVDVFSAGVIFYILLCGQQPFKGS-------------NHRQVVEQNKKCEIDFQILD--------------------SNQKIPQAA
.. |. |.|. |.||| ||.||| || |. | .. |. .|.. || .. .. | .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC
KILVKQMLAKDPINRPTSQECLNSPFF
| |...|| .|| .|.| ..||| |..
KDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 27560.AA | S_TKc | 1-265 | 30 | 3.4e-78 | 267.0 | SMART | 6-231 (231) | Show / Hide |
Range on Protein: 1-265 Range on HMM: 6-231/231 Sequence Identity: 30% (86 aa) MIGKGGFSRVFLAQDKFSRENYAIKVITKDKLLQQTKGIKSLLNEIQIMKELDNVNGCLKLIGVYETDSSVNLILEYIKG--GELVKKIKLKDKQN---- ||||.|..|.....| . . .|||.| .....||||.|. . ||..|... ... ...||. | |.| . || . .. KIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP FTIENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIEDDINSTKIKIADFGLATYDSTVLNDFLFKKCGTPGFLAPEVLSNKDTHKLYDH-KVDVFSAG |. | .|. |. ||...|...||||||||.|||. . |||.|||||. |||| ..||||| |.. |.|. | | FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCG VIFYILLCGQQPFKGSNHRQVVEQNKKCEIDFQILDSNQKIPQAAKILVKQMLAKDPINRPTSQECLN-------SPFF .|.|..|||. || .. .. .. . .. || .....| ||| .||| |.|. |.| CILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 27560.AA | Pkinase | 2-265 | 29 | 1.1e-74 | 259.2 | Pfam | 7-293 (293) | Show / Hide |
Range on Protein: 2-265 Range on HMM: 7-293/293 Sequence Identity: 29% (89 aa) IGKGGFSRVFLAQDKFSRENYAIKVITKDKLLQQTKGIKSLLNEIQIMKEL--DNVNGCLKLIGVYETDSSVNLILEYIKGG----ELVKKIKLKDKQNF ||.|.|..|.....| ... .|.|.| |.. . . .. .|.||||||.| .|. ..|....|..... ...|| || .| |. ... .| IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNI---VRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCF --TIENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIE-DDINSTKIKIADFGLA----TYDSTVLNDFLFKKCGTPGFLAPEVLSNKDTHKLYDHKVD . . . | || .|...|...||||||||.|||| .. .....||.||||| . .. ...| ||||...||||. ... |..||| YFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF----CGTPWYMAPEVIR---GGQYYGPKVD VFSAGVIFYILLCGQQPFKGS------NHRQVVEQNKKCEIDFQILDSNQ----------------KIPQAAKILVKQMLAKDPINRPTSQECLNSPFF ..|.|.|.|..|||. ||.|. ...|...........|.. .. ......| ..| .|.||| ||| ...|..|.| MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 27560.AA | AGC | 1-265 | 21 | 3.8e-74 | 190.22 | In-house | 6-395 (395) | Show / Hide |
Range on Protein: 1-265 Range on HMM: 6-395/395 Sequence Identity: 21% (86 aa) MIGKGGFSRVFLAQDK------FSRENYAIKVITKDK-LLQQTK-GIKSLLNE------------IQIMKELDN---------VNGCLK-LIGVYETDSS .||||.|..|.|...| . . ||.||. |.. .. | .. ..| .|...... | | ..... VIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDH --VNLILEYIK---------GG-ELVKKIKLK-DKQNFTIENMRQLMQN-------ILIALAHIHQ-RKIIHRD-LKPDNILIEDDINSTKIKIADFGLA . ...||.. || || .. . ... |. | | . |. || ..|. ..||||| |||.|||. .| ||..||||. TYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---GHIKLTDFGLC TY------------------------------------------------DSTVLN--DFLFKKCG--TPGFLAPEVLSNKDTHKLYDHKVDVFS--AGV . |.| . | || || ..|||.| |.. .| | |. KEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL--------YGKACDWWSFGLGC IFYILLCGQQPFKGSN---------HRQVVEQNKK-------CEIDFQ-----ILDSNQKIPQAAKILVKQMLAKDPINRPT----------SQECLNSP ..| .|.|. || | | .. . |. . ... | . .... . || |.|..| ||| .|.. .| | | LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP FF .| WF |
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| Kinase | 27560.AA | CAMKL | 2-265 | 29 | 2.4e-62 | 197.69 | In-house | 7-297 (297) | Show / Hide |
Range on Protein: 2-265 Range on HMM: 7-297/297 Sequence Identity: 29% (88 aa) IGKGGFSRVFLAQD-KFSRENYAIKVITKDKLLQQTKGIKS-----------LLNEIQIMKELD---NVNGCLKLIGVYETDSS------VNLILEYIKG .|||.|. | ||.. .. .| .|||.| |.|. .. | . |||||| |. | || |.||.. ..|..||. | LGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPN-IIKLYEVIETPEHDIETKKIYLVMEYCSG GE--LVKKIKLKDKQN--FTIENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIEDDINSTKIKIADFGLATY-DS--TVLNDFLFKKCGTPGFLAPEV || | .|. . . . .. . |.. . |. |....|...|.|||.||.|||. .. |. .|||.|||.... . ...| ||.| . |||. GEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEI LSNKDTHKLYD-HKVDVFSAGVIFYILLCGQQPFKGSNHR-----QVVEQNKKCEIDFQILDSNQKIPQAAKILVKQMLAKDPINRPTSQECLNSPFF .. ..| || |||. |.||| | ..||. ||.. .. . . .| .. . ... .. | ..|| ..| ||| .. .| |.. FQG--NNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 27560.AA | CDPK | 2-265 | 34 | 2.3e-60 | 183.96 | In-house | 7-271 (271) | Show / Hide |
Range on Protein: 2-265 Range on HMM: 7-271/271 Sequence Identity: 34% (95 aa) IGKGGFSRVFLAQDK-FSRENY-AIKVITKDKLLQQTKGIKSLLNEIQIMKELD--NVNGCLKLIGVYETDSSVNLILE--YIKGGELVKKIKLKDKQNF .|||.|. |.....| . . |.|.| |... .. . .....||| |.|.|| |. .|. .|. . . ...| | .|||| .|. | . | LGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQ-QQQFFNEIEILKQLDHPNI---IKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH--F TIENM-RQLMQNILIALAHIHQRKIIHRDLKPDNILIEDDINST----KIKIADFGLAT-YDSTVLN---DFLFKKCGTPGFLAPEVLSNKDTHKLYDHK | | . .. |. || |....|...|.|||||| ||| . . ... ||. |.|... .|. . . . ..|||| .||||| .| |. | T-EKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQN-QKIEDKKMSQRCGTPYYIAPEVL----QKK-YNEK VDVFSAGVIFYILLCGQQPFKGSNHRQVVEQNKKCEIDFQILDSNQKIPQAAKILVKQMLAKDPINRPTSQECLNSPFF .|. |.||| |||||| || | | ...|. ||.. .| . ..| . || |...|| .|| .| ..|..|. | | CDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFE-GPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 27560.AA | RSK | 1-265 | 30 | 3.4e-59 | 202.98 | In-house | 3-278 (278) | Show / Hide |
Range on Protein: 1-265 Range on HMM: 3-278/278 Sequence Identity: 30% (85 aa) MIGKGGFSRVFLAQDK---FSRENYAIKVITKDKLLQQTKGIKSLLNEIQIMKELDNVNGCLKLIGVYETDSSVNLILEYIKGGELVKKIK-LKDKQNFT . |.||. ||| . . .. || ||. | |. | | .. . |..|... . .| ...|.. . ||.||..|||| .... | . |. VLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFS IENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIED-DINSTKIKIADFGLATYDSTVLNDFLFKKCGTPGFLAPEVLSNKDTHKL-YDHKVDVFSAGV . .. | .| |. |.||..||||||||.||| .| . |. ||. |||.. . . | . . |.| ..|||.| . .. .|. .|..| || EDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLGV IFYILLCGQQPFKG---SNHRQVVEQNKKCEIDFQILDSNQKIPQAAKILVKQMLAKDPINRPT-----SQECLNSPFF . | .| |. ||.| .|. .. .. .|..... .. .|.. |.|| |...|| .|| .|.. .| ...|.| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLT-MPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 27560.AA | ULK | 1-265 | 27 | 1.7e-58 | 200.66 | In-house | 6-324 (324) | Show / Hide |
Range on Protein: 1-265
Range on HMM: 6-324/324
Sequence Identity: 27% (90 aa)
MIGKGGFS-RVFLA--QDKF-SRENYAIKVITKDKLLQQTKG------IKSLLNEIQIMKELD------NVNGCLKLIGVYETD--SSVNLILEYIKGGE
..||| | |. . ... . . .|.|.| |.|. .. . ...| |||||||.|. . . . ||. ..||. . .|.|| ||
CLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-H-IVKLYDWFETSNHNNIYIIMEYCNGGD
LVKKIKLK-------DKQNFTIENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIEDDI---NSTK------IKIADFGLATY-DSTVLNDFLFK-KC-
| . || . |.... . .| .. |. .. ..|...|||||.||.|||| ... .|.| .||||||.| |. ....... .
LEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVN
-----GTPGFLAPEVLSNK-DTHKLYDHKVDVFSAGVIFYILLCGQQPFKGSNHRQVVEQ--------------NKKCEIDFQILDSNQKIPQAAKILVK
||| . ||..|... . ||.|.|..| |.||| .| |. ||... .. ... |. |.|.. ....|| . | | .
EKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIR
QMLAKDPINRPTSQECLNSPFF
.|| .|. | . .| .| |.|
RMLQYDEKDRISWEEIFNHPWF
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| Kinase | 27560.AA | ULK | 1-265 | 28 | 2.5e-58 | 200.08 | In-house | 6-329 (329) | Show / Hide |
Range on Protein: 1-265 Range on HMM: 6-329/329 Sequence Identity: 28% (95 aa) MIGKGGFSRVFLAQDKFSR----ENYAIKVITKDKLLQQTKG------IKSLLNEIQIMKELD--------NVNGCLKLIGVYETD--SSVNLILEYIKG ..||| | .|. . .| . | .|.|.| |.|. |. . ...| |||.|||.|. . | . ||. ..||. . .|.|| | CLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPN-IVKLYDWFETSNHNNIYIIMEYCNG GELVKKIKLK--------DKQNFTIENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIEDDI---NSTK------IKIADFGLATY-DST-----VLND | | . || . |.... . .| .. || .. ..|...|||||.||.|||| ... .|.| .||||||.| |. .. GDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMT FL----FKKCGTPGFLAPEVLSNK-DTHKLYDHKVDVFSAGVIFYILLCGQQPFKGSNHRQVVEQNKKCE----------IDFQILD-----SNQKIPQA .. . |||| . ||..|... . ||.|.|..| |.||| .| |. ||... .. ..|... . |. | |. ....| . CVNEKRL--CGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPE AKILVKQMLAKDPINRPTSQECLNSPFF | | ..|| .|. | . .| .| |.| CKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 27560.AA | TyrKc | 1-265 | 22 | 8.3e-16 | 32.9 | SMART | 6-280 (280) | Show / Hide |
Range on Protein: 1-265 Range on HMM: 6-280/280 Sequence Identity: 22% (68 aa) MIGKGGFSRVFLAQDKFSRENYAIKVITKDKLLQQTKGIKSLLNEIQIMKEL--DNVNGCLKLIGVYETD-------SSVNLILEYIKGGELVKKIKLKD ..| | | .|.... | .. |.|.. .|. .. ...|..||..| .. | ..|.|| .. . ...|| ..| | . .. . KLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPN-IVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR KQNFTIENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIEDDINSTKIKIADFGLA--TYDS------TVLNDFLFKKCGTPGF----LAPEVLSNKDT .. .. . . . . | ...|....||||| |.|. .. .||.||||. || . . .|.| . .|||.. PK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----N HKLYDHKVDVFSAGVIFY-ILLCGQQPFKG-----SNHRQVVEQNKKCEIDFQILD-----SNQKIPQAAKILVKQMLAKDPINRPTSQECLNSPFF .. . .| ||.| || . |. |||| | . ..|.|. |. . | . . |.. . || . || .||| .|. .| YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 27560.AA | Pkinase_Tyr | 39-148 | 28 | 3e-13 | 45.5 | Pfam | 47-158 (270) | Show / Hide |
Range on Protein: 39-148 Range on HMM: 47-158/270 Sequence Identity: 28% (33 aa) IKSLLNEIQIMKEL-DNVNGCLKLIGVYE-TDSS--VNLILEYIKGGELVKKIKLK--DKQNFTIENMRQLMQNILIALAHIHQRKIIHRDLKPDNILIE ......|..|||.| .. | ..|.|| . . . ...|| ..| | . . . |||..|.. . | . | .... .....||||| |.|.. REDFMREAKIMKQLGHHPN-IVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT DDINSTKIKIADFGLA . . ..||.||||| E---NNVVKICDFGLA |
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