Gene 23205 (Tetrahymena)

23205

Species: Tetrahymena
Alias: 23205, 1162, n.23205, PreTt23205, 105.m00172, TTHERM_00690090
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2a

Sequence

Name Sequence Type Origin Length Description Download
23205.AA Protein None 447 None Fasta, JSON
23205.kin_dom Protein Kinase Domain None 265 None Fasta, JSON
23205.NA RNA None 1260 None Fasta, JSON

Protein domain

Protein domains of 23205.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 23205.AA Ciliate-E2a 50-314 40 1.1e-154 458.71 In-house 1-275 (275) Show / Hide 
Range on Protein: 50-314
Range on HMM: 1-275/275
Sequence Identity: 40% (116 aa)

YEIIKPLGKGTYGCVYHAKQKREPQREVAIKVISLNNIDKLPLQYVKREVQISKILDHPNIIKFIETYIDKKNIYIVMEYCSGGSLL-----EWTFKEG-
|..|| .|||..|.||.|..|.........|.|  ....| . .|...|..|.. ||||||||..|.|.|..|.|.|||||.||.|.      ..|.|  
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-DVLDVMKKLFY-AVNYMHSRNVIHRDLKLENILFE---SES-QNSDIKIIDFGLAKKV--GDDDRRHTMVGSVAYMVINIKRLEMNKQLLLQNTPEVMF
 .. |.|..|.. ...|||.||..|||||.|||||.   ..| |||||||||||||...   . .......|.  |. .            ..| .||..
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAP-----------EVLNNKEVLK

NKSYNKSCDVWSLGIIMYRLICGQLPFKS------QQQIHDAKLYFDNPI-WKTISKEGKDLIRRMIVYNPKIRITIQDALKHKWF
.|.| ..||.||.|.|.|.|.||..|||        ||... |..|. |. |. .||| |||...| ...|| |||.|.||.|.||
HKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 23205.AA Ciliate-E2 50-314 28 3.3e-100 339.21 In-house 1-365 (365) Show / Hide 
Range on Protein: 50-314
Range on HMM: 1-365/365
Sequence Identity: 28% (108 aa)

YEIIKPLGKGTYGCVYHAKQKREPQRE-----------------VAIKVISLNNIDKLPLQYVKREVQISK----------------ILDHPNIIKFIET
|..|| .|.|..|.|| .|........                 |.|| . .... |  ....|.| .| .                .|.||||||..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YI--DKKNIYIVMEYCSGGSLLE-----WTFK-----------EGDVLDVMKKLFY---------------AVNYMHSRN-VIHRDLKLENILFESESQN
..  |..|||.|||||.||.|..     ....           |  ....||....               |..|.||.| .||||.|.|||||      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SDIKIIDFGLAKKVGDDDRRHTMVGSVAYMVINIK------------RLEMNKQ-----LLLQNTPEVMFNKS---------YNKSCDVWSLGIIMYRLI
  ||||||||.||. ||  ..|. .. ... .. |            ..  | .      .    ||.  .|.         |...||.||||.|.|...
--IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

CGQLPFKSQQQIHDAKLYFDNP--------------IWKTISKEGKDLIRR----MIVYNPKIRIT-IQDALKHKWF
.|..||  ||||.. |. |..|              .|| .|.|.||||..    |....|. ||| ....|.|.||
FGKPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 23205.AA CAMK 55-314 24 2.3e-91 294.64 In-house 1-425 (425) Show / Hide 
Range on Protein: 55-314
Range on HMM: 1-425/425
Sequence Identity: 24% (107 aa)

PLGKGTYGCVYHAKQKREPQ-----------REVAIKVISLNNID--------------------------KLPLQYVKREVQISKI-------LDHPNI
 ||.|..| |. ...|. ..           ..||||.|. . ..                             .. |.||..| |        ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKFIETYID-------------------KKNIYIVM---EYCSGG----SLLEWT--------------------FKEGDVLDVMKKLFYAVNYMHSRNV
||..|.| |                   .|..|.||   ||||||     |...                     |.| ..  ... .  ||.|.||.|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKLENILFESESQNSD--------------IKIIDFGLAKKVGD------------------------DDRRHTMVGSVAYMVINIKRLEMNKQLL
.|||||.||||. . . .||              |||||||.|.|. .                        ..  .|..|. .||              
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMA-------------

LQNTPEVMFNKS--------------YNKSCDVWSLGIIMYRLICGQLPFKSQ-------------------QQIHDAKLYFDNPI------------WK
    |||   |.              |...||.||.|.|.| . || .|| .                    ..|  .| .|. |             |.
---APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

TISKE--------GKDLIRRMIVYNPKIRITIQDALKHKWF
 ||.|         |||||.| ...|. |.||...|.|.|.
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 23205.AA CDPK 50-314 39 2.4e-91 280.4 In-house 1-271 (271) Show / Hide 
Range on Protein: 50-314
Range on HMM: 1-271/271
Sequence Identity: 39% (115 aa)

YEIIKPLGKGTYGCVYHAKQK-REPQREVAIKVISLNNIDKLPL-QYVKREVQISKILDHPNIIKFIETYIDKKNIYIVME--YCSGGSLLE-----WTF
| | |.||||..| |. .|.|    |. ||.|.|. ... .    | ...|. | | ||||||||. |.| |.||.|||||  ||.|| |..       |
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

KEGDVLDVMKKLFYAVNYMHSRNVIHRDLKLENILFESESQNS----DIKIIDFGLAKKVGDD-----DRRHTMVGSVAYMVINIKRLEMNKQLLLQNTP
.| .  ..|.... ||||.||.|..||||| |||||.| . .|    .||.||.|..|| . .     .   ...| . |.                  |
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYI-----------------AP

EVMFNKSYNKSCDVWSLGIIMYRLICGQLPFKSQ------QQIHDAKLYFDNPIWKTISKEGKDLIRRMIVYNPKIRITIQDALKHKWF
||  .|.||..||.||.|.|.| |.||  ||  .      ... . |  |. | |. ||.| |||||.|..|.|| |.. |.||.|.||
EVL-QKKYNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 23205.AA S_TKc 50-314 32 1.6e-85 291.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-314
Range on HMM: 1-231/231
Sequence Identity: 32% (94 aa)

YEIIKPLGKGTYGCVYHAKQKREPQREVAIKVISLNNIDKLPLQYVKREVQISKILDHPNIIKFIETYIDKKNIYIVMEYCSG--GSLLE-----WT---
|||....|||..|.|| .. |.  .|.||||.|.         . ..||.|| |  .||||.|..... | ...|.|||||.|  |.|..      .   
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FKEGDVLDVMKKLFYAVNYMHSRNVIHRDLKLENILFESESQNSDIKIIDFGLAKKVGDDDRRHTMVGSVAYM---VINIKRLEMNKQLLLQNTPEV
   | | ..  .|. .. |..|.||...|||||| ||||. .      |||.|||||...      .|..|.  ||   |.                   
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL-------------------

MFNKSYNK-SCDVWSLGIIMYRLICGQLPFKSQQQIHDAKLYFDNPIWKTISKEGKDLIRRMIVYNPKIRITIQDALK-------HKWF
    .|.| .||.||.|.|.| ..||. ||       . .. |..      |.|.||.||.. ...|. |.|. .||.       | ||
----GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 23205.AA Ciliate-E2-Unclassified 50-314 26 1e-72 247.89 In-house 1-352 (352) Show / Hide 
Range on Protein: 50-314
Range on HMM: 1-352/352
Sequence Identity: 26% (96 aa)

YEIIKPLGKGTYGCVYHAKQKREPQREV-----AIKVISLNNIDKLP----------LQYVK--------REVQ-ISKILDHPNIIKFIETYIDKKNIYI
|.||| .|.| .|.||....| .   ..     ..|... .   ..           ..  |        .. | | . ..||.|.|....  ||.||||
YKIIKQIGQGGFGKVYKCQHKKQK--QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYCSGGSLLEWT----------------------FKEGDVL-----DVMKKLFYAVNYMHSRN-VIHRDLKLENILFESESQNSDIKIIDFGLAKKVG
||||| ||.|...                       | |  ..     . .. .  . .|.|. | .||||.|.||||| .. .|  |||||||..|| .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

DD----------------DRRHTMVGSVAYMVINIKRLEMNKQLLLQNTPEVMFNKSYN----KSCDVWSLGIIMYRLICGQLPFK--------------
..                .. .|..|.  ||                . |||. .. |.    ..||.||||.|.| .. |..||.              
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q------------YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQW

--------SQQQIHDAKLYFDNPIW----KTISKEGKDLIR----RMIVYNPKIRITIQDALKHKWF
         .|.|.. ...|..  |    |..|.|.||.|.    .|...||. |||....|.| ||
INNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 23205.AA CAMK1 50-212 35 3.4e-59 170.69 In-house 1-180 (276) Show / Hide 
Range on Protein: 50-212
Range on HMM: 1-180/276
Sequence Identity: 35% (64 aa)

YEIIKPLGKGTYGCVYHAKQKREP--QREVAIKVIS-LNNIDK----LPLQYVKREVQISK---ILDHPNIIKFIETYIDKKNIYIVMEYCSGGSLLEW-
||..| .|.|. . || ...|. .  ....|||.|.   ...|      ......|..| |    .||||||||.| | ... .|.|||...|| |..  
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

----TFKEGDVLDVMKKLFYAVNYMHSRNVIHRDLKLENILFESESQNSDIK--IIDFGLAKKVGDDD-RRHTMVGSVAYM
     . | |  ..||... ||.||||... ||||| ||.|..... .|.||  |.||||.|....|.    |..|.  |.
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYV
Kinase 23205.AA CAMKL 50-212 34 9.9e-58 182.75 In-house 1-200 (297) Show / Hide 
Range on Protein: 50-212
Range on HMM: 1-200/297
Sequence Identity: 34% (70 aa)

YEIIKPLGKGTYGCVYHAKQKREPQREVAIKVISLNNIDKLPLQY-------------VKREVQISKILD---HPNIIKFIETYIDKKN------IYIVM
|.|.| ||||..| |  |. .| ....||||.|  . | . |                ..||.|| | |.   ||||||. |.. ....      ||.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCSGGS--LLEWT---------FKEGDVLDVMKKLFYAVNYMHSRNVIHRDLKLENILFESESQNSDIKIIDFGLAKKVGD-----DDRRHTMVGSVAY
||||||.  |...          ..|..     . .  ||||.||....|||.|.||||. .   |  |||||||.. .  .     ..  .|  || .|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

M
|
M
Kinase 23205.AA Pkinase 50-212 35 4.2e-57 200.83 Pfam 1-178 (293) Show / Hide 
Range on Protein: 50-212
Range on HMM: 1-178/293
Sequence Identity: 35% (64 aa)

YEIIKPLGKGTYGCVYHAKQKREPQREVAIKVISLNNIDKLPLQYVKR--EVQISKILDHPNIIKFIETYIDKKNIYIVMEYCSGG----SLL-------
|.|....|.|..||||... | ... .||.|.|.. ....  .|.  |  |.|| | |.||||....... ||..||.||||| ||    .|        
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

EWTF--KEGDVLDVMKKLFYAVNYMHSRNVIHRDLKLENILFESESQN-SDIKIIDFGLAKK--VGDDDRRHTMVGSVAYM
. .|   | .. ..|. .. ...|.||...||||||.||||. .. .. ...||.||||||.     .   .| .|.  ||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYM
Kinase 23205.AA CAMK-Unique 50-212 28 3.1e-50 163.95 In-house 1-242 (363) Show / Hide 
Range on Protein: 50-212
Range on HMM: 1-242/363
Sequence Identity: 28% (69 aa)

YEIIKPLGKGTYGCVYHAKQKREPQREVAIKVISL--NNIDKLPLQ----------------YVKREVQISKILDHPNIIKFIET----YIDKK------
|. ....|.|..| || .. . ..  . |.|.. .    ..|. .|                  |||.|| | .|||||||. ..    . |.|      
YKMHRIIGHGNFGHVYECMDRETGK-KWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL

---------NIYIVMEYCSGGSLLEWTFK-------------------------E--GDVLDVMKKLFYAVNYMHSRNVIHRDLKLENILFESESQ----
         ..||||||| || |..|  |                         |   |.. .| .|  ||.|||| ...|||||||||.. .. .    
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH

---------NSDIKIIDFGLAKKVGDDDRRH---TMVGSVAYM
         |..||..||||....     .|   ||.|.  ||
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYM
Kinase 23205.AA ULK 50-212 29 1.3e-45 157.89 In-house 1-214 (324) Show / Hide 
Range on Protein: 50-212
Range on HMM: 1-214/324
Sequence Identity: 29% (64 aa)

YEIIKPLGKGTYG-CVYHAKQKREP--QREVAIKVISLNNIDKLPLQ--------YVKREVQISKILD---HPN--IIKFIETYIDK--KNIYIVMEYCS
|.... ||||..|  || .. |.    .  ||.|.|..... | ...          |.|.|| |.|.   |||  |.|... . ..  .||||.|||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSLL----------EWT-----FKEGDVLDVMKKLFYAVNYMHSRNVIHRDLKLENILFESESQ--NSD-------IKIIDFGLAKKVGDD----DRRH
|| |           | |     . |  .. ..| .  .  ..|..|.||||.|..|||     .  .|        .|| |||.||.| ..    . ..
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TMV------GSVAYM
|.|      |.  ||
TCVNEKRIKGTPLYM
Kinase 23205.AA ULK 50-212 27 2.2e-45 156.4 In-house 1-218 (329) Show / Hide 
Range on Protein: 50-212
Range on HMM: 1-218/329
Sequence Identity: 27% (61 aa)

YEIIKPLGKGTYGCVYHAKQKREP---QREVAIKVISLNNIDKLP--------LQYVKREVQISKILD--------HPNIIKFIETYIDK--KNIYIVME
|.... ||||..| || .. |.     .  ||.|.|... ... .        .| .|.|..| | |.        ||||.|... . ..  .||||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCSGG---SLLE------------WTFKEGDVLDVMKKLFYAVNYMHSRNVIHRDLKLENILFES-----ESQNSD------IKIIDFGLAKKVGDD---
|| ||   ....             .. |  .. ..| .  .  ..|..|.||||.|..|||        .|.  .      .|| |||.||.| .|   
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK--KVHPNGVLKIADFGFAKHVDNDNME

-DRRHTMV------GSVAYM
 .  .|.|      |.  ||
QQMMMTCVNEKRLCGTPLYM
Kinase 23205.AA CAMK1 231-314 36 5.7e-30 84.27 In-house 182-276 (276) Show / Hide 
Range on Protein: 231-314
Range on HMM: 182-276/276
Sequence Identity: 36% (35 aa)

PEVMFN---KSYNKSCDVWSLGIIMYRLICGQLPFKSQQ-Q------IHDAKLYFDNPIWKTISKE-GKDLIRRMIVYNPKIRITIQDALKHKWF
|||  .   | | |.||.|| |.| | | ||  || .   .      |  ... |..| |  ||..  ||.|. |.. .|| |.|....|.|.|.
PEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 23205.AA ULK 231-314 30 6.6e-26 87.48 In-house 220-329 (329) Show / Hide 
Range on Protein: 231-314
Range on HMM: 220-329/329
Sequence Identity: 30% (34 aa)

PEVMF----NKSYN-KSCDVWSLGIIMYRLICGQLPFKSQQQIHDA-----KLYFD----------NPIW-------KTISKEGKDLIRRMIVYNPKIRI
|..      .| |. . ||.||||.|.| .. |. ||...    .      ||. .          .|.        ..||.| |||||||..|..| ||
PQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRI

TIQDALKHKWF
.... ..|.||
SWEELFNHPWF
Kinase 23205.AA CAMKL 244-314 32 3.8e-25 77.06 In-house 218-297 (297) Show / Hide 
Range on Protein: 244-314
Range on HMM: 218-297/297
Sequence Identity: 32% (27 aa)

DVWSLGIIMYRLICGQLPFKSQQ-----------QIHDAKLYFDNPIWKTISKEGKDLIRRMIVYNPKIRITIQDALKHKWF
|.||.|.|.| ..||.|||. .               . .. .  |||. .| . .||||.| . ||. |.||.. ..|.|.
DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 23205.AA Pkinase 231-314 29 1e-24 88.49 Pfam 180-293 (293) Show / Hide 
Range on Protein: 231-314
Range on HMM: 180-293/293
Sequence Identity: 29% (34 aa)

PEVMF-NKSYNKSCDVWSLGIIMYRLICGQLPFKSQ------------QQIHDAKLYFDNPIWKTIS-----------------KEGKDLIRRMIVYNPK
|||   .. | ...|.||.|.|.| ..||..||...            ..| ...| || | | .||                 .|.||.|.... ..||
PEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK

IRITIQDALKHKWF
 |.|....|.|.||
KRPTAEQILQHPWF
Kinase 23205.AA ULK 231-314 32 3.4e-23 79.21 In-house 216-324 (324) Show / Hide 
Range on Protein: 231-314
Range on HMM: 216-324/324
Sequence Identity: 32% (35 aa)

PEVMF----NKSYN-KSCDVWSLGIIMYRLICGQLP----FKSQQ---------------QIHDAKLYFDNPI-WKTISKEGKDLIRRMIVYNPKIRITI
|..      .| |. . ||.||||.|.| .. |. |    | .|.               .| . .. |..|.  . ||.| |||||||..|..| ||..
PQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISW

QDALKHKWF
.. ..|.||
EEIFNHPWF
Kinase 23205.AA CAMK-Unique 231-314 25 4.3e-22 69.56 In-house 244-363 (363) Show / Hide 
Range on Protein: 231-314
Range on HMM: 244-363/363
Sequence Identity: 25% (31 aa)

P--------------EVMFNKSYNKSC----DVWSLGIIMYRLICGQLPFKSQ--------------QQIHDAKL-YFDNPIWKT---ISKEGKDLIRRM
|              ||  .  |   |    | |||| ||| ..|| .|| ..              . |  ... .||.. |     ||.|.||.. . 
PEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCC

IVYNPKIRITIQDALKHKWF
 .. |. |...  .|.| |.
MTVDPDHRWSAKELLEHQWI
Kinase 23205.AA Pkinase_Tyr 50-137 30 3.2e-15 52.16 Pfam 1-96 (270) Show / Hide 
Range on Protein: 50-137
Range on HMM: 1-96/270
Sequence Identity: 30% (30 aa)

YEIIKPLGKGTYGCVYHAKQK---REPQREVAIKVISLNNIDKLP--LQYVKREVQISKIL-DHPNIIKFIETYI-DKKN--IYIVMEYCSGGSLLE
 ...| ||.| .| ||... |    ... .||.|..  .. ..    ..   ||..| | | .||||....   . ...   |||||||. .|.||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase 23205.AA TyrKc 50-314 23 2.8e-14 8.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-314
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

YEIIKPLGKGTYGCVYHAKQKREPQREVAIKVISLNNIDKLPLQYVKREVQISKIL--DHPNIIKFIETYIDK-------KNIYIVMEYCSGGSLLEWTF
 . .| || | .| ||... |    ..||.|..  .      ..   || .| . |  .||||....   ...       . ..|||||...|.|..   
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KEGDVLDVMKKLFYAV------NYMHSRNVIHRDLKLENILFESESQNSDIKIIDFGLAKKVGDD-------DRRHTMVGSVAYMVINIKRLEMNKQLLL
| .. | . ..| ...      .| ||.|.|||||   |.|  ..     .|| ||||.....||       |  ... .. . ... |. .        
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM--------

QNTPEVMFNKSYNKSCDVWSLGIIMYRLI-CGQLPF-------KSQQQIHDAKLYF-DNPIWKT--------ISKEGKDLIRRMIVYNPKIRITIQDALK
   ||... . ..   |||| |. |. .   || |        .| |...         |. .          ..|  .....   ..|. | | ..   
--APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--

HKWF
|. |
HECF
Kinase 23205.AA Pkinase_Tyr 157-200 45 0.005377 10.77 Pfam 125-165 (270) Show / Hide 
Range on Protein: 157-200
Range on HMM: 125-165/270
Sequence Identity: 45% (20 aa)

NYMHSRNVIHRDLKLENILFESESQNSDIKIIDFGLAKKVGDDD
.| .|.| |||||   |.| ..   |  .|| |||||. . .||
EYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDD
Kinase 23205.AA Pkinase_Tyr 231-253 34 1.978621 2.08 Pfam 183-205 (270) Show / Hide 
Range on Protein: 231-253
Range on HMM: 183-205/270
Sequence Identity: 34% (8 aa)

PEVMFNKSYNKSCDVWSLGIIMY
||..... ..   |||| |. |.
PECINYGKFTTKSDVWSFGVLMW