Gene 17681 (Tetrahymena)

17681

Species: Tetrahymena
Alias: 3758.m00218, TTHERM_01049230, 211.m00049, PreTt17681, 17681, 281
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2a

Sequence

Name Sequence Type Origin Length Description Download
17681.AA Protein None 626 None Fasta, JSON
17681.kin_dom Protein Kinase Domain None 293 None Fasta, JSON
17681.NA RNA None 1881 None Fasta, JSON

Protein domain

Protein domains of 17681.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 17681.AA Ciliate-E2a 141-433 40 2.5e-171 508.54 In-house 1-275 (275) Show / Hide 
Range on Protein: 141-433
Range on HMM: 1-275/275
Sequence Identity: 40% (124 aa)

YDVKRVIGSGAYASVVIAEKKIDGSLFAVKSLSKAHIYQTTDGKAEIENELALMRLVRHKNVMRLFEVFDADSSIKIVLELVEGGQLFDLMKKNPNLTWF
|.....||.|...||..|..|..|  ||.| ..| ..||...||....||...|| ..|.|...|.||.  ......|.|..|||.|.| .|.. .....
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--EIGLIMKQILSVNLQSFFPKNIGILSTSSINQFIIFVLQKKGLEALHSQNIMHRDLKPENILMR--SKES---LDLVIGDFGLAQKA--DAKKYLYLK
  ||  ||.|.|.                             .||. .|..|||||||||||||..  ||.|   .|..| |||||...  | |||.. |
IQEICDIMQQLLW-----------------------------QGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQK

CGTPGYVAPEVINLKE--EQTQYDTQCDIFSAGAIFYKLCVHKPLFQGVTHAEVLQENKSVNFNLNCQD-VKDLPPLAQDLLKQLLKCDPKQRITATEAL
|||||||||||.|.||  ...||||.||..|.|.||| |...||.|.| |..|.||.||  ....||..  ....  ..||.|..|..|||.||||..||
CGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQAL

KHKFF
.|..|
NHPWF
Kinase 17681.AA Ciliate-E2 141-433 26 1.3e-94 320.68 In-house 1-365 (365) Show / Hide 
Range on Protein: 141-433
Range on HMM: 1-365/365
Sequence Identity: 26% (106 aa)

YDVKRVIGSGAYASVVIAEKKIDGSLFA----------------VKSLSKAHIYQTTDGKAEIENELALMRLVR----------------HKNVMRLFEV
|.. ..||.|...||  .... .. .||                ||.  .|  ..  ... .|..|. .|| ..                |.|.....|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FD--ADSSIKIVLELVEGGQLFDLMKKN-----------PNLTWFEIGLIMKQILSVNLQSFFPKNIGILSTSSINQFIIFVLQKK----------GLEA
|    |..| .|.|...|| |||..|.|            ..|..||. ||||||....                          |          .|| 
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFK-------------------------TKAEFYIACIILALEY

LHSQN-IMHRDLKPENILMRSKESLDLVIGDFGLAQKAD-----------AKKYLYLK----------------------CGTPGYVAPEVINLKE----
|||.| |.|||.||||||.       . | ||||..|.|           .|.|.. |                      ||||||.|||..| |.    
LHSKNNIIHRDIKPENILF-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ

-EQTQYDTQCDIFSAGAIFYKLCVHKPLFQGVTHAEVLQENKSVNFNLNCQ--------------DVKDLPPLAQDLLKQ----LLKCDPKQRIT-ATEA
 .|..||..|||.|.| |.| ..  || |        .|..|  .....|.              . |.... ..||.|.    .|..||..||| . ..
QKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI

LKHKFF
|.|..|
LNHPWF
Kinase 17681.AA S_TKc 141-433 26 2.1e-71 244.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 141-433
Range on HMM: 1-231/231
Sequence Identity: 26% (83 aa)

YDVKRVIGSGAYASVVIAEKKIDGSLFAVKSLSKAHIYQTTDGKAEIENELALMRLVRHKNVMRLFEVFDADSSIKIVLELVEG--GQLFDLMKKNPN--
|.. |.||.||...|  . .| .| ..|.| ..             |..|.....  .|.|. .|..||.  ... .|.|...|  | |||..||..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LTWFEIGLIMKQILSVNLQSFFPKNIGILSTSSINQFIIFVLQKKGLEALHSQNIMHRDLKPENILMRSKESLDLVIGDFGLAQKADAKKYLYLKC
    ..  ..  .|.||..                              .|| .||..|.||||||||||. .     . |.||||| .       .  |
LRFPFPE-HARFYMYQICC------------------------------ALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFC

GTPGYVAPEVINLKEEQTQYDT-QCDIFSAGAIFYKLCVHKPLFQGVTHAEVLQENKSVNFNLNCQDVKDLPPLAQDLLKQLLKCDPKQRITATEALK--
||| |.||||.       .|..  ||. | | |.| ... .|.|.  .......  .              .| | |.....|. ||..|.|| |||.  
GTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----HKFF
     | .|
WDIKCHPWF
Kinase 17681.AA CAMK 282-433 22 2.6e-48 153.35 In-house 191-425 (425) Show / Hide 
Range on Protein: 282-433
Range on HMM: 191-425/425
Sequence Identity: 22% (54 aa)

GLEALHSQNIMHRDLKPENILMRSKES---------------LDLVIGDFGLAQKADA------------------------KKYLYLKCGTPGYVA-PE
... .||.||.||||||||||. ....                .. | |||.|.| |                          . ..  ||||.|.| ||
AVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE

VINLK----------EEQTQYDTQCDIFSAGAIFYKLCVHKPLFQGV-------------THAEVLQENKSVNFNLNCQDVKDLP---------------
|.| |          ||.. |. .||. |.| | | . . .| |.|              .  | ..  .. ...     .....               
VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF

-----PLAQDLLKQLLKCDPKQRITATEALKHKFF
     . ..||....|. ||..|.|....|.|...
HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 17681.AA AGC 282-433 22 5.9e-47 118.29 In-house 165-395 (395) Show / Hide 
Range on Protein: 282-433
Range on HMM: 165-395/395
Sequence Identity: 22% (54 aa)

GLEALHS-QNIMHRD-LKPENILMRSKESLDLVIGDFGLAQKADAK---------------------------------------------------KYL
.|| ||| ..| ||| |||||||. ..    . . ||||. .   .                                                   .  
ALEYLHSHMGIIHRDYLKPENILLDED--GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRT

YLKCG--TPGYVAPEVINLKEEQTQYDTQCDIFS--AGAIFYKLCVHKPLFQGVT----------HAEVLQENKSVNFNLNCQ------------DVKDL
.  ||  || |.|||..        |. .||. |   |...| . . .| |.| .          ..|. |  .. .. .|..            ... .
WTFCGPCTPEYMAPEIL--------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWF

PPLAQDLLKQLLKCDPKQRIT----------ATEALKHKFF
 | |.||.|.||. ||..|..          | |  .|..|
SPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 17681.AA Pkinase 281-433 29 1.6e-46 165.55 Pfam 119-293 (293) Show / Hide 
Range on Protein: 281-433
Range on HMM: 119-293/293
Sequence Identity: 29% (53 aa)

KGLEALHSQNIMHRDLKPENILMRSKESL--DLVIGDFGLAQK--ADAKKYLYLKCGTPGYVAPEVINLKEEQTQYDTQCDIFSAGAIFYKLCVHKPLFQ
.||| .||..|.||||||||||. ..  .  .. |.||||| .     .  ..  ||||.|.|||||.   ... |.. .|..|.| |.| ..  .|.|.
RGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPPFP

GV------THAEVLQENKSVNFNLNCQDVKDLP-----------------PLAQDLLKQLLKCDPKQRITATEALKHKFF
|       .. ........  .  ...   . .                 . ..|..| .|. |||.|.||...|.|..|
GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 17681.AA CAMK1 286-366 47 2.5e-41 117.87 In-house 124-207 (276) Show / Hide 
Range on Protein: 286-366
Range on HMM: 124-207/276
Sequence Identity: 47% (40 aa)

LHSQNIMHRDLKPENILMRSK-ESLDLV--IGDFGLAQKADAKK-YLYLKCGTPGYVAPEVINLKEEQTQYDTQCDIFSAGAIFY
.||..|.||||||||.| ..| |  ...  | ||||... | .  ...  |||||||||||.. |.  . ||  ||..|.| |.|
MHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKACDMWSIGVITY
Kinase 17681.AA Ciliate-E2-Unclassified 281-433 27 4.6e-40 136.65 In-house 154-352 (352) Show / Hide 
Range on Protein: 281-433
Range on HMM: 154-352/352
Sequence Identity: 27% (56 aa)

KGLEALHSQN-IMHRDLKPENILMRSKES-LDLVIGDFGLAQKADA----------------KKYLYLKCGTPGYV----APEVINLKEEQTQYDTQ---
.||| ||..| | |||.||||||. .. . . . | |||.. | .                 .. .. .||||.|     ||||.    .. .||..   
QGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL----QGQNYDHSKAY

-CDIFSAGAIFYKLCVHKPLFQGVTHAE----------------VLQENKSVNFNLNCQDV----KDLPPLAQDLLK----QLLKCDPKQRITATEALKH
 |||.| | |.| ..  .. |.. .  .                ..|. |  |.. ....     |...| |.|...    ..|| .|..|||. ..|.|
KCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNH

KFF
 .|
PWF
Kinase 17681.AA CDPK 287-433 36 7.5e-39 116.94 In-house 120-271 (271) Show / Hide 
Range on Protein: 287-433
Range on HMM: 120-271/271
Sequence Identity: 36% (58 aa)

HSQNIMHRDLKPENILMRSKESL-----DLVIGDFGLAQKADAK-----KYLYLKCGTPGYVAPEVINLKEEQTQYDTQCDIFSAGAIFYKLCVHKPLFQ
||.||.||||||||||  ||..      .... |.|.. | | .     |... .|||| |.||||.     | .|. .||| |.| | | | .  | | 
HSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVL-----QKKYNEKCDIWSCGVILYILLCGYPPFY

GVTHAEVLQENKSVNFNLNCQDVKDLPPLAQDLLKQLLKCDPKQRITATEALKHKFF
| .  |...  |  ..... .. ..    |.|| ...|  |||.|..| .||.|. |
GKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 17681.AA RSK 283-433 31 2.1e-36 127.26 In-house 117-278 (278) Show / Hide 
Range on Protein: 283-433
Range on HMM: 117-278/278
Sequence Identity: 31% (51 aa)

LEALHSQNIMHRDLKPENILMRSKE-SLDLVIGDFGLAQK--ADAKKYLYLKCGTPGYVAPEVINLKEEQTQ-YDTQCDIFSAGAIFYKLCVHKPLFQG-
.| ||.| | ||||||||||  ... .  ... |||.. .  .| .. ..  |.|  |.|||...  . |   .| .||..| |.. | . . .| ||| 
VEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLGVLMYEMLTGCPPFQGP

--VTHAEVLQENKSVNFNLNCQDVKDLPPLAQDLLKQLLKCDPKQRIT-----ATEALKHKFF
   ...|...  .. .|.|.    . | . |.||....|. ||..|..     | | ..|..|
NDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 17681.AA ULK 282-433 27 7.9e-33 113.83 In-house 138-324 (324) Show / Hide 
Range on Protein: 282-433
Range on HMM: 138-324/324
Sequence Identity: 27% (52 aa)

GLEALHSQNIMHRDLKPENILMRSKESLD----------LVIGDFGLAQKAD----AKKYLYLKC------GTPGYVAPEVINLK-EEQTQYDTQCDIFS
|. .||..||.|||.||.|||.  .              | |.|||.|.. |    ..  ..  .      ||| | ||.... . |.. .||  |||.|
GFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWS

AGAIFYKLCVHKPL----FQGVT--HAEVLQE---------NKSVNFNLNCQDVKDLPPLAQDLLKQLLKCDPKQRITATEALKHKFF
 | ||| .   |.     |.     ... ..          |. ..|.... . . . |  .||....|. |.|.||. .| ..|..|
LGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 17681.AA CAMK 146-251 14 1.1e-26 82.41 In-house 1-190 (425) Show / Hide 
Range on Protein: 146-251
Range on HMM: 1-190/425
Sequence Identity: 14% (27 aa)

VIGSGAYASVVIAEKKIDG------------SLFAVKSLSKAHIYQ------------------------TTDGKAEIENELALMRL-------VRHKNV
..|.|... |  .. | ..              .|.| ..|  .                          .   ......|...|..       ..|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

MRLFEVFD------------ADSS--------IKIVL---ELVEGG----QLFDLMKKNPN---------------LTWFEIGLIMKQILS
 .|.||..              |         . .|.   |...||     |||  .....               .|  |   ...||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICS
Kinase 17681.AA Pkinase 141-251 30 2.5e-26 94.15 Pfam 1-119 (293) Show / Hide 
Range on Protein: 141-251
Range on HMM: 1-119/293
Sequence Identity: 30% (36 aa)

YDVKRVIGSGAYASVVIAEKKIDGSLFAVKSLSKAHIYQTTDGKAE-IENELALMRLVRHKNVMRLFEVFDADSSIKIVLELVEGG----QLFDLMK--K
| ..|.||||....| .. .| .| ..||| ..| |.    |  .  . .|...|. ..|.|. ||...|  ...| .|.|..|||     |||...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

NPNL--TWFEIGLIMKQILS
. ..  .. |.  .|.|||.
HGCFYFSEWECKFYMYQILR
Kinase 17681.AA CAMKL 141-251 23 2.7e-26 80.79 In-house 1-138 (297) Show / Hide 
Range on Protein: 141-251
Range on HMM: 1-138/297
Sequence Identity: 23% (32 aa)

YDVKRVIGSGAYASVVIAEK-KIDGSLFAVKSLSKAHIYQTTDGKAE-----------IENELALMRLVR---HKNVMRLFEVFDADSS------IKIVL
|.. ...| |... |  |.  .. |   |.| . |  |   .  |.            |. | ..|....   |.|...|.||.. ..       | .|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVEGGQ--LFDLMKKNPN----LTWFEIGLIMKQILS
|...||   |||  .|...    ..  |   . .||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVS
Kinase 17681.AA CAMK1 141-229 29 4e-25 69.92 In-house 1-97 (276) Show / Hide 
Range on Protein: 141-229
Range on HMM: 1-97/276
Sequence Identity: 29% (29 aa)

YDVKRVIGSGAYASVVIAEKKI---DGSLFAVKSLS-KAHIYQTT--DGKAEIENELALMRLV---RHKNVMRLFEVFDADSSIKIVLELVEGGQLFD
| .. .||.|| . |. ...|    .|  .|.| .. | .. . .    .. .|||.. |. |    | |.  ..|... |. . .|.||| || |||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFD
Kinase 17681.AA CAMKL 286-344 37 4.6e-20 60.57 In-house 143-206 (297) Show / Hide 
Range on Protein: 286-344
Range on HMM: 143-206/297
Sequence Identity: 37% (24 aa)

LHSQNIMHRDLKPENILMRSKESLDLVIGDFGLAQKADA-----KKYLYLKCGTPGYVAPEVIN
.||..| |||.||||||  .. .  . | |||.. . .       . |   ||.| | |||...
CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQ
Kinase 17681.AA AGC 141-238 18 2.8e-18 42.44 In-house 1-144 (395) Show / Hide 
Range on Protein: 141-238
Range on HMM: 1-144/395
Sequence Identity: 18% (26 aa)

YDVKRVIGSGAYASVVIAEKK------IDGSLFAVKSLSKAH-IY-----QTTDGKAE--------IENELALMRLVR----------HKNVMR-LFEVF
.....||| |..  |  ..||        | ..|.| |.|.| |.     .    ..|        . .|   . ...          | .. . |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

DADSS--IKIVLELVE---------GG-QLFDLMK---KNPNLT
  ..   . .|.|...         ||  ||  ..   |.  ..
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFD
Kinase 17681.AA CDPK 141-251 26 4e-17 49.26 In-house 1-114 (271) Show / Hide 
Range on Protein: 141-251
Range on HMM: 1-114/271
Sequence Identity: 26% (31 aa)

YDVKRVIGSGAYASVVIAEKK-IDGSLF-AVKSLSKAHIYQTTDGKAEI-ENELALMRLVRHKNVMRLFEVFDADSSIKIVLE--LVEGGQLFDLMKKNP
|. |.|.|.|.. .| .. .| ...    |.|  .|  . .  .   ..  ||.....   | |. ...|..  .  . ||.|  ...||.|||  . . 
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQ--QQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKG

NLTWFEIGLIMKQILS
..| .|  .||.||||
HFTEKEAAYIMRQILS
Kinase 17681.AA Ciliate-E2-Unclassified 141-251 18 6.9e-17 55.12 In-house 1-154 (352) Show / Hide 
Range on Protein: 141-251
Range on HMM: 1-154/352
Sequence Identity: 18% (28 aa)

YDVKRVIGSGAYASVVIAEKKIDGSLFAVKSLSKAHIYQ----TTDGKAEIENELALMRL------------------VRHKNVMRLFEVFDADSSIKIV
| . ..||.|....|  ...| .. ..| | ..|..||      .    .. ........                    | .....|..|  .  | ||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LELVEGGQLFDLMKKNPN-----------------LTWFEIG-----LIMKQILS
.|..||| |.. .||...                 .| ...       ...|||.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQ
Kinase 17681.AA ULK 141-251 20 6.5e-14 45.8 In-house 1-137 (324) Show / Hide 
Range on Protein: 141-251
Range on HMM: 1-137/324
Sequence Identity: 20% (28 aa)

YDVKRVIGSGAYA-SVVIAEKKID---GSLFAVKSLSKAHIYQTTDG------KAEIENELALMRLVR---HKN--VMRLFEVFDAD--SSIKIVLELVE
| .....|.|...  |  ...|..   . ..|.|  .|  . .          .  ..||  .|.      |.|  . .|...|  .    | |..|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGQLFDLMKKNPNLTWFE----------IGLIMKQILS
|| |....||| .|.  .          .  ..|||..
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICN
Kinase 17681.AA TyrKc 141-433 20 1.8e-13 -5.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 141-433
Range on HMM: 1-280/280
Sequence Identity: 20% (69 aa)

YDVKRVIGSGAYASVVIAEKKIDGSLFAVKSLSKAHIYQTTDGKAEIENELALMRLV--RHKNVMRLFEVFDAD-------SSIKIVLELVEGGQLFDLM
   ....|.||.  |. .. |      |||.| . .       .... .|. .|. .  .|.|. ||. |   .         . ||.|....| | |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KKNPNLTWFEIGLIMKQILSVNLQSFFPKNIGILSTSSINQFIIFVLQ-KKGLEALHSQNIMHRDLKPENILMRSKESLDLV-IGDFGLAQKADAK----
.|. .                                .  ... | .|  .| | |||.|. ||||   |.|  ..     | |.||||. . . .    
RKHRPK------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQG

---KYLYLKC--GTPG-----YVAPEVINLKEEQTQYDTQCD----------IFSAGAIFYKL-----CVHKPLFQGVTHAEVLQENKS---VNFNLNCQ
   .|   |   |. .       |||.|        . |. |          ||. |.  |       .  . ... | . . .   ..   . |     
ESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-----

DVKDLPPLAQDLLKQLLKCDPKQRITATEALKHKFF
 |   . . | . ||  . ||..| | .|   |..|
-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase 17681.AA CAMK1 405-433 37 6.1e-12 30.94 In-house 248-276 (276) Show / Hide 
Range on Protein: 405-433
Range on HMM: 248-276/276
Sequence Identity: 37% (11 aa)

LAQDLLKQLLKCDPKQRITATEALKHKFF
.| |..|..|..|||.|.|....|.|...
EAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 17681.AA RSK 144-233 25 7.3e-10 32.6 In-house 1-94 (278) Show / Hide 
Range on Protein: 144-233
Range on HMM: 1-94/278
Sequence Identity: 25% (24 aa)

KRVIGSGAYASVVIAEKKI---DGSLFAVKSLSKAHIYQTTDGKAEIENELALMRLVR-HKNVMRLFEVFDADSSIKIVLELVEGGQLFDLMKK
 .| | |.| .| .  |..    | ..|.| |.|| | |.    .    |   . ... |... .|...|. .. . ...|...|| ||.  .|
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQK
Kinase 17681.AA CAMKL 400-433 20 4.9e-09 24.82 In-house 265-297 (297) Show / Hide 
Range on Protein: 400-433
Range on HMM: 265-297/297
Sequence Identity: 20% (7 aa)

KDLPPLAQDLLKQLLKCDPKQRITATEALKHKFF
....  ..||....|. .|..|.|. . ..|...
YHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 17681.AA Pkinase_Tyr 141-225 22 0.000219 15.48 Pfam 1-92 (270) Show / Hide 
Range on Protein: 141-225
Range on HMM: 1-92/270
Sequence Identity: 22% (22 aa)

YDVKRVIGSGAYASVVIAEKK----IDGSLFAVKSLSKAHIYQTTDG---KAEIENELALMRLV-RHKNVMRLFEVFD-ADSS--IKIVLELVEGG
    ...|.||. .|. .. |     ..   |||.| |    ....    ...  .|...|.   .|.|. ||  |    . .  | ||.|....|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG