Gene 10118 (Tetrahymena)
10118
Sequence
Protein domains of 10118.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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PH | 10118.AA | PH | 44-143 | 17 | 3e-06 | 28.23 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 44-143 Range on HMM: 1-82/82 Sequence Identity: 17% (17 aa) RSIEGTLFRKSIKKGYWKSNTYQLIGNKLIKFTAESGKPEKFANIENYRLEKIKLEEKGDKDIKYGFRLTHNCKFVELYARNKEHMLMWFELVKRQCVLT .||.| .|| | || | .. |. . . || .. ......... . .|...| . .......|.| .|.. .. . VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDCTVRE-P-----------CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN |
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Kinase | 10118.AA | Ciliate-E2a | 149-410 | 49 | 3e-177 | 526.27 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-275/275 Sequence Identity: 49% (136 aa) YSTIKLMGKGNFARVYYARSKLTGGEFAVKAFEKDKFAQIEIDRPALIKEISILRKMNHPGVIKMYEVYENETHIFLVNELLKGGELFHKLKGHGQFDEV |..||..|||||..||.|. | || .||.|.|.| |..|..... ....||.|.|...|| .||.|||||.|....|| |...||||..|.| ...|.| YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE --YVAQLMTTLL-DSIHYISQRNILHRDIKPENLILR--SKNND--TDLCLADFGLADYYDPK-GGYMFQRCGTPGYVAPEVLADKI------YDFKVDT .....| || . .||. ||||.|||.||||.... |||.. .|....|||||...|.. . ||||.||||||||||||. | || |.| IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM FSAGVIMFILLTGSSPFKGKSYDEIVIKNYNCTIDFNYNEMGKYLSAECFDLLQKLLKKDPLERYSAIQALNHPWF .|.|||..|||.|..|||||.|.||...|..| ||||..|. ...| ||.||..|.|.||| .|..|.|||||||| WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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Kinase | 10118.AA | CAMK1 | 149-410 | 37 | 1.6e-103 | 301.84 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-276/276 Sequence Identity: 37% (103 aa) YSTIKLMGKGNFARVYYARSKLT---GGEFAVKAFE-KDKFAQIEI-DRPALIKEISILRKM---NHPGVIKMYEVYENETHIFLVNELLKGGELFHKLK | .| |.| |. || . | | | ..|.|... |. .. . . || .||.|..| .|| .||.||.|| ..|. || ||..|||||.. YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV GHGQFDEVYVAQLMTTLLDSIHYISQRNILHRDIKPENLILRSKNNDTDLC--LADFGLADYYDPKGGYMFQRCGTPGYVAPEVLAD---KIYDFKVDTF |.. | . .| .|. ..|. ...| |||.||||| ...| .| .. .|||||. ..|.. ..|...||||||||||||.. | || ..| . EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW SAGVIMFILLTGSSPFKGKS-YDEIVIKNYNCTIDFNYNEMGKYLSAECFDLLQKLLKKDPLERYSAIQALNHPWF |.||| .|||.| .|| ... ..|. |. .| ..| .. ... . | |.. ..|..|| .||.. |.|||||. SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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Kinase | 10118.AA | Ciliate-E2 | 149-410 | 27 | 2.7e-98 | 332.88 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-365/365 Sequence Identity: 27% (105 aa) YSTIKLMGKGNFARVYYARSKLTGGEFA----------------VKAFEKDKFAQIEIDRPALIKEISILRKMN----------------HPGVIKMYEV | ||. |.|||. ||... .... .|| ||.... . ... . .. .||.|.|..| || .|||||. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YE--NETHIFLVNELLKGGELFHKLK------------GHGQFDEVYVAQLMTTLLD---------------SIHYISQRN-ILHRDIKPENLILRSKNN .. ....|.|| |...||.||. .| . ..|.| ....|. .|. ..|. ..| |.||||||||... FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- DTDLCLADFGLADYYDPK----------GGYMFQR----------------------CGTPGYVAPEVLA---------DKIYDFKVDTFSAGVIMFILL ....||||. .||.. . ||| . ||||||.|||.| | ||.|.| .|.|||....| ---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML TGSSPFKGKSYDEIVIKNYNCTIDFNYNEMG-------------KYLSAECFDLLQK----LLKKDPLERYS-AIQALNHPWF .| || ... .| |||. .|.. |..| || ||..| .|.||| .|.. . |.|||||| FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 10118.AA | CAMK | 154-410 | 24 | 1.4e-95 | 308.49 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 154-410 Range on HMM: 1-425/425 Sequence Identity: 24% (105 aa) LMGKGNFARVYYARSKLTGGE------------FAVKAFEKDKFAQ------------------------IEIDRPALIKEISILRK-------MNHPGV |.|.|. |. .. |.|.|. .|.| .|.| . || . .||.|..| ..|| . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IKMYEVYEN-------------------ETHIFLVN---ELLKGGEL----FHKLKGHGQ---------------FDEVYVAQLMTTLLDSIHYISQRNI ||.|||||. ..|...| |. |||| | ... ||. |.| ..... ... .||. ..|| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI LHRDIKPENLILRSKNNDTD--------------LCLADFGLADYYDPK-----------------------GGYMFQRCGTPGYVA-PEVLADKI---- |||.||||. | ..|.|.| . ..|||.| ..||. | | .||||.|.| |||| | VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM ----------YDFKVDTFSAGVIMFILLTGSSPFKGK-------------SYDEIVIKNYNCTIDFNYNEMGK-------------------YLSAECFD |..|.| |.|||..|.|.| .|| |. .. |. | .. || .. . ..|.|| | QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD LLQKLLKKDPLERYSAIQALNHPWF |..|.|..|| .|... |.|||||. LIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 10118.AA | CDPK | 149-410 | 38 | 1e-85 | 262.89 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-271/271 Sequence Identity: 38% (107 aa) YSTIKLMGKGNFARVYYARSK-LTGGEF-AVKAFEKDKFAQIE-IDRPALIKEISILRKMNHPGVIKMYEVYENETHIFLVNE--LLKGGELFHKLKGHG | | |||.| |. . | |. | |.| .|.. . | ... ...|| ||.. || .||.||.|. | ....| | ...||||| . . | YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQ--FFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKG QFDEVYVAQLMTTLLDSIHYISQRNILHRDIKPENLILRSKNNDT----DLCLADFGLADYYDPK----GGYMFQRCGTPGYVAPEVLADKIYDFKVDTF .|.| |. |. .| . |. ..|| |||.||||. . ||..|. .. . |.|.. ..|.. . .| |||||| |.||||| | |. |.| HFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIW SAGVIMFILLTGSSPFKGKSYDEIVIKNYNCTIDFNYNEMGKYLSAECFDLLQKLLKKDPLERYSAIQALNHPWF |.|||..||| |. || ||. ||. | .. .|.. | . | |. || .|.| .|| |.|| |||.|||| SCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEW-DHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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Kinase | 10118.AA | S_TKc | 149-410 | 30 | 1.9e-80 | 274.48 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-231/231 Sequence Identity: 30% (86 aa) YSTIKLMGKGNFARVYYARSKLTGGEFAVKAFEKDKFAQIEIDRPALIKEISILRKMNHPGVIKMYEVYENETHIFLVNELLKG--GELFHKLKGHGQ-- | ... ||| |..|| .| | || ..|.| ...||.||.| .|| ..|.|.|... .|...| |.. | |.||. .| .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG ----FDEVYVAQLMTTLLDSIHYISQRNILHRDIKPENLILRSKNNDTDLCLADFGLADYYDPKGGYMFQRCGTPGYVAPEVLADKIYDF-KVDTFSAGV |.| .. .| ... . |. ...|.|||.||||. | . . ..||||| . |||| |.||||| |.. |.| | |. LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC IMFILLTGSSPFKGKSYDEIVIKNYNCTIDFNYNEMGKYLSAECFDLLQKLLKKDPLERYSAIQALN-------HPWF |....|.| || .. .. . . | |. |...|.|.||| .|..| .||. |||| ILYEMLCGYPPFP----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 10118.AA | Pkinase | 149-410 | 30 | 1.6e-74 | 258.72 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-293/293 Sequence Identity: 30% (89 aa) YSTIKLMGKGNFARVYYARSKLTGGEFAVKAFEKDKFAQIEIDRPALIKEISILRKMNHPGVIKMYEVYENETHIFLVNELLKGG----ELFHKLK--GH | ... |.|.|..|| .. | || ..||| ..|.. . . ... ||.|....||| ....|...|...|| .| |.. || .||. .. | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GQF--DEVYVAQLMTTLLDSIHYISQRNILHRDIKPENLILR-SKNNDTDLCLADFGLADYY-DPKGGYMFQRCGTPGYVAPEVLA-DKIYDFKVDTFSA | | .| . |. .| . |. ...|.|||.||||. . ..|......||||| . ... | .||||.|.||||. .. |. ||| .|. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVIMFILLTGSSPFKGK------SYDEIVIKNYNCTIDFNYN-----------------EMGKYLSAECFDLLQKLLKKDPLERYSAIQALNHPWF |.|....|.| ||.|. . .... .. . ..|.. . ...| || |.. ..|.||| .|..| |.|.|||| GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 10118.AA | CAMKL | 149-410 | 30 | 1.2e-72 | 231.11 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-297/297 Sequence Identity: 30% (93 aa) YSTIKLMGKGNFARVYYARS-KLTGGEFAVKAFEKDKFAQIEIDRPA-----------LIKEISILRKMN---HPGVIKMYEVYENETH------IFLVN | .| |||.|. | |. ..|| . |.| .|.| ... . . .||.|....| || .||.|||.|...| |.|| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELLKGGE--LFHKL--KGHGQ--FDEVYVAQLMTTLLDSIHYISQRNILHRDIKPENLILRSKNNDTDLCLADFGLADYYDP----KGGYMFQRCGTPGY |. ||| ||... .||. ..| .. . ... ..|. ...| ||||||||. | ...| . ..|||.. .|.| .| . .||.| | EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY VAPEVLAD--KIYD-FKVDTFSAGVIMFILLTGSSPFKGKSY----DEIVIKNYNCTIDFNYNE-MGKYLSAECFDLLQKLLKKDPLERYSAIQALNHPW |||.... | || .||| |.|||.. ...| ||.. .| .. . . |. .. |.. ...| .| ||..|.|...| .|... | .|||| MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW F . M |
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Kinase | 10118.AA | CAMK-Unique | 149-410 | 23 | 4.7e-63 | 206.92 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-363/363 Sequence Identity: 23% (84 aa) YSTIKLMGKGNFARVYYARSKLTGGEFAVKAFEKDKFAQIEIDRP-----------------ALIKEISILRKMNHPGVIKMYEV----YENET------ | .... |.||| || . . || ..|.| ..| . ..... . | .|..|... .|| || |.. .. .. YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQT-HGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL ---------HIFLVNELLKGGELFHKLKG--------------------HGQFDE--VYVAQLMTTLLDSIHYISQRNILHRDIKPENLILRSKNN---- ....| |.. ||.|| .. |.| | ....|. || . | . .| |||.|.||. ... . IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH ---------DTDLCLADFGLADYYDPKGGY--MFQRCGTPGYVAP--------------EVLADKIYDFKV----DTFSAGVIMFILLTGSSPFKGKSYD .... |.||||. .|. . . | .|||| |.|| ||.. || .. |. | ||||...|.|..|| . . | HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED --------EIVIKNYNCTI-DFNYNEMGK--YLSAECFDLLQKLLKKDPLERYSAIQALNHPWF || . . . .| .. | | | |....... || | || ..| |.|. RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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Kinase | 10118.AA | Ciliate-E2-Unclassified | 149-410 | 24 | 1.1e-61 | 211.24 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-352/352 Sequence Identity: 24% (88 aa) YSTIKLMGKGNFARVYYARSKLTGGEF-----AVKAFEKD-KFAQIEIDRPALIKEIS----------------ILRKMNHPGVIKMYEVYENETHIFLV | || |.|.|. || .. | .. .. . |. ... | . ... .||. ||. ..|| ..||... ... .|..| YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV NELLKGG-----------------ELFHKLKGHGQFDEVYVA-----QLMTTLLDSI-HYISQRNILHRDIKPENLILRSKNNDTDLCLADFGLADYYDP |...|| .|||..| .|.| .. ... .|. . ..... ||.||||||||... .... ....|||.. .|. MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ KGGY---------------MFQRCGTPGYV----APEVLADKIYD----FKVDTFSAGVIMFILLTGSSPFKGKSYDE---------------IVIKNY- .. | ..||||.| ||||| . || .|.| .| |||.. .|.| ||....... ....| NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK NCTIDFN-YNE--MGKYLSAECFDLLQ----KLLKKDPLERYSAIQALNHPWF .. |.|. ... | .| |. |... |.|||.| .|... |.|||||| QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 10118.AA | DCAMKL | 149-358 | 38 | 2e-60 | 186.49 | In-house | 1-226 (279) | Show / Hide |
Range on Protein: 149-358 Range on HMM: 1-226/279 Sequence Identity: 38% (87 aa) YSTIKLMGKGNFARVYYARSKLTG-GEFAVKA---------FEKDKFAQIEIDRPALI-------KEISILRKMNHPGVIKMYEVYENETHIFLVNELLK |.. .. |.|||| |. .| . || ..| | | | | ||. ... |.||..|..|| .|..||... |||..|| |. . YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQ--IDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQ GGELFHKLKGHGQFDEVYVAQLMTTLLDSIHYISQRNILHRDIKPENLILRS-KNNDTDLCLADFGLADYYDPKGGYMFQRCGTPGYVAPEVLADKIYDF || || . . | | | .|| | . |. .|| ||||||||| . . | |.||||| . . | .. |||| |||||.|. . | GGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGC KVDTFSAGVIMFILLTGSSPFKGKSYDE ||| .|||| ||| | ||.. |. KVDIWAAGVILYILLCGFPPFRSPDNDQ |
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Kinase | 10118.AA | RSK | 152-410 | 28 | 2.5e-59 | 203.44 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 152-410 Range on HMM: 1-278/278 Sequence Identity: 28% (81 aa) IKLMGKGNFARVYYARSK---LTGGEFAVKAFEKDKFAQIEIDRPALIKEISILRKMN-HPGVIKMYEVYENETHIFLVNELLKGGELFHKLKGHGQ--- .|. |.| . |. | . || ..|.| .| |..| . | .|..|| . || ... ..... |....|. |...||||| .|. ... LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FDEVYVAQLMTTLLDSIHYISQRNILHRDIKPENLILRSKNND-TDLCLADFGLADYYDPK-GGYMFQRCGTPGYVAPEVLA----DKIYDFKVDTFSAG |.| ... | .. . .. |. | |||.|||| .. ... . . | |||.. . ... .. . |.| |.|||.|. .. .| .| .| | FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VIMFILLTGSSPFKG---KSYDEIVIKNYNCTIDFNYNEMG--KYLSAECFDLLQKLLKKDPLERYS-----AIQALNHPWF |.|. .||| .||.| .. .|| . ....... |. .|||.|. ||..|.|..|| |.. | . ..|||| VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLT---MPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 10118.AA | TyrKc | 149-410 | 19 | 8.1e-14 | 0.69 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 149-410 Range on HMM: 1-280/280 Sequence Identity: 19% (59 aa) YSTIKLMGKGNFARVYYARSKLTGGEFAVKAFEKDKFAQIEIDRPALIKEISILRKM--NHPGVIKMYEVYENE-------THIFLVNELLKGGELFHKL . .| | |.| .|| .. | . ||| .|. | ....|..|..| .|| ....| | . ...| |. ..| | . | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL KGHGQFDEVYVAQLMTTLLDS---IHYISQRNILHRDIKPENLILRSKNNDTDLCLADFGLADYYDPK------GGYMFQRC--GTPG-----YVAPEVL . |. . ...| .. |....|. |||. | . ... .||||. . . . . | .. |. . |||.. RKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI ADKIYDFKVDTFSAGVIMF-ILLTGSSPFKG-----KSYDEIVIKNYNCTIDFNYNEMGKY--------LSAECFDLLQKLLKKDPLERYSAIQALNHPW .... .| | .| || |. |. | .| | .| .|. ... . .. . .. ..| ... .. . || .| . . | NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV----IEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC F | F |
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Kinase | 10118.AA | DCAMKL | 385-410 | 46 | 1.9e-08 | 21.81 | In-house | 254-279 (279) | Show / Hide |
Range on Protein: 385-410 Range on HMM: 254-279/279 Sequence Identity: 46% (12 aa) DLLQKLLKKDPLERYSAIQALNHPWF || ...|..|| ||.| | . ||| DLISHMLQVDPEKRYTAEQIMQHPWV |
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Kinase | 10118.AA | Pkinase_Tyr | 149-244 | 23 | 0.000103 | 16.59 | Pfam | 1-106 (270) | Show / Hide |
Range on Protein: 149-244 Range on HMM: 1-106/270 Sequence Identity: 23% (26 aa) YSTIKLMGKGNFARVYYARSK----LTGGEFAVKAFEKDKFAQIE--IDRPALIKEISILRKM-NHPGVIKMYEVYE-NETH--IFLVNELLKGGELFHK . .| |.|.| .|| .. | |. . ||| |.. . . .. ....|..|.... .|| ....| | . . |..| |. ..| | . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCRE--DFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY LKGH---GQ |. | .| LRKHREDKQ |
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Kinase | 10118.AA | Pkinase_Tyr | 319-355 | 35 | 7.757904 | 0.07 | Pfam | 182-220 (270) | Show / Hide |
Range on Protein: 319-355 Range on HMM: 182-220/270 Sequence Identity: 35% (14 aa) APEVLADKIYDFKVDTFSAGVIMFILLT-GSSP-FKGKS |||....... | | | || |. ..| | .| ..| | APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMS |