Gene 10066 (Tetrahymena)

10066

Species: Tetrahymena
Alias: 139, 10066, PreTt10066, 3828.m01327, TTHERM_00077200, 5.m00417
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2a

Sequence

Name Sequence Type Origin Length Description Download
10066.AA Protein None 482 None Fasta, JSON
10066.kin_dom Protein Kinase Domain None 248 None Fasta, JSON
10066.NA RNA None 1449 None Fasta, JSON

Protein domain

Protein domains of 10066.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10066.AA Ciliate-E2a 46-293 37 3.1e-144 427.45 In-house 14-275 (275) Show / Hide 
Range on Protein: 46-293
Range on HMM: 14-275/275
Sequence Identity: 37% (100 aa)

KVFKVQRIQDGKIFAAKVIKRAKLEENKYKDKFVAMLLNEYRVLSESKHKNIIQMEEIYQDHDQLVYIMEFLVGGEVYSRLRQVKRFSEE--VAAEILKN
.|...|..|.|| ||.|.... |....|...... . .| .| |   .|.|||.. |.|.|.... ..||.. ||| |....| ||| ||  ....|...
SVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQL---DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQ

LT-EGLLHIHNKKIVHRDLKLENILFV-NKTDN----DCKLIDFGFAEKI--N-YEKLESRAGTPGFLPPELFKLGP------YTEKGDIFSLGVILYCL
|. .||...|...|.|||||.|||||  .....    |.|.||||.|..|  . .... .. ||||...||....        |..| |..|.|||.|.|
LLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYIL

VSGCSPFKGKTYKDVLENNRRCAISYDQPV-WNKISDECKHLIRRMVEVDPKKRYACNDILKSKWM
..|..|||||||...|..|..| |....|. |.|.|.|||.|...|.|.|||||. ....|...|.
LCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 10066.AA CAMK 46-293 21 1.7e-84 272.04 In-house 9-425 (425) Show / Hide 
Range on Protein: 46-293
Range on HMM: 9-425/425
Sequence Identity: 21% (88 aa)

KVFKVQRIQDG------------KIFAAKVIKRAKLE------------ENKYKDKF---------VAMLLNEYRVLSESK-------HKNIIQMEEIYQ
||.........            . .|.|.|.. ||              .| | |           .....|.....  .       |.|||.. |.|.
KVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYE

DHDQ-------------------LVYIM---EFLVGG----EVYSRLRQV---------------KRFSEEVAAEILKNLTEGLLHIHNKKIVHRDLKLE
|...                   .. .|   |.  ||    ........                .||.|. |. . . . ... ..|...|||||||.|
DPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPE

NILFVNKTD---------------NDCKLIDFGFAEKIN-------------------------YEKLESRAGTPGFLP-PELFK--------------L
|||.... |               |. |.|||||| |..                          .|.. . |||.. . ||...               
NILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEK

GPYTEKGDIFSLGVILYCLVSGCSPFKGK-------------TYKDVLENNRRCAISYDQPV------------WNKISDE--------CKHLIRRMVEV
 .|..| |. |.||||| ...|..|| |.             .... .|. ...  ... |             |..||||        ||.|||.| .|
PYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQV

DPKKRYACNDILKSKWM
||.||. . ..|. .||
DPEKRMTIEQCLNHPWM
Kinase 10066.AA Ciliate-E2 46-293 23 9.5e-81 274.57 In-house 14-365 (365) Show / Hide 
Range on Protein: 46-293
Range on HMM: 14-365/365
Sequence Identity: 23% (85 aa)

KVFKVQRIQDGKIFA----------------AKVIKRAKLEENKYKDKFVAMLLNEYR-------------VLSESKHKNIIQMEEIYQ--DHDQLVYIM
.|.|.......| ||                .|. . |.   .|.. ... . ....|             .|.. .|.|||.| | .|  | . . ..|
SVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVM

EFLVGGEVYSRLR------------QVKRFSEEVAAEILKNLTE---------------GLLHIHNKK-IVHRDLKLENILFVNKTDNDCKLIDFGFAEK
|.. ||. .....            . |.|.|. ...| | ...               .| ..|.|. |.|||.|.|||||       .|.||||.. |
EYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-------IKIIDFGLSKK

IN------------YEKLESR----------------------AGTPGFLPPELFKLGP---------YTEKGDIFSLGVILYCLVSGCSPFKGKTYKDV
..            ..... .                      .||||...|| .. ..         |..| ||.|||||||....|  ||        
YDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------

LENNRRCAISYDQP--------------VWNKISDECKHLIRR----MVEVDPKKRYA-CNDILKSKWM
....  | |....|               |.|.|.|||.||..    | ..||.||.   ..||. .|.
QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 10066.AA CAMK1 46-293 31 1.4e-75 219.18 In-house 14-276 (276) Show / Hide 
Range on Protein: 46-293
Range on HMM: 14-276/276
Sequence Identity: 31% (83 aa)

KVFKVQRIQ---DGKIFAAKVIK-RAKLEENKYKDKFVAMLLNEYRVLSES---KHKNIIQMEEIYQDHDQLVYIMEFLVGGEVYSRLRQVKRFSEEVAA
.|.......   .|| .| |.|. .  .....   |  ..|.||  ..  .   .| |||...|.|.. . .  .|| . |||   |  . . ..|. |.
EVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ-K-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIVEKGNYTEKDAR

EILKNLTEGLLHIHNKKIVHRDLKLENILFVNK-TDNDCK--LIDFGFAEKINYE--KLESRAGTPGFLPPELFKL---GPYTEKGDIFSLGVILYCLVS
.| |.. . . ..| | ||||||| ||.|...|  | . |  ..||| . ... .  ... . ||||.  || ..     ||  . |..| |||.| |  
HIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLC

GCSPFKGKT-YKDVLENNRRCAISYDQPVWNKISDE-CKHLIRRMVEVDPKKRYACNDILKSKWM
|..|| ... ..  .| . .| . .. | |..|||.  |..|. | |||||||| | ..|. .| 
GYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
S_TKc 10066.AA S_TKc 43-293 25 1.3e-70 241.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 43-293
Range on HMM: 1-231/231
Sequence Identity: 25% (71 aa)

YQK----------KVFKVQRIQDGKIFAAKVIKRAKLEENKYKDKFVAMLLNEYRVLSESKHKNIIQMEEIYQDHDQLVYIMEFLVG--GEVYSRLRQVK
|..          ||.|.. . .|.|.| |.||               ....| ..|.. .|.||... ...|| | |  .||.. |  |........ .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

R------FSEEVAAEILKNLTEGLLHIHNKKIVHRDLKLENILFVNKTDNDCKLIDFGFAEKINYEKLESRAGTPGFLPPELFKLGPYTE-KGDIFSLGV
|      |.| .|. ... . ..| ..|...|.||||| ||||. .      |..|||.| ..      .  ||| ...||..   .|.  | |. |.|.
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

ILYCLVSGCSPFKGKTYKDVLENNRRCAISYDQPVWNKISDECKHLIRRMVEVDPKKRYACNDILK-------SKWM
||| ...|. ||   ... .... .              |.|.|..||.. ..||.||. . ..|.         |.
ILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 10066.AA Pkinase 46-293 26 3.8e-68 237.49 Pfam 14-293 (293) Show / Hide 
Range on Protein: 46-293
Range on HMM: 14-293/293
Sequence Identity: 26% (76 aa)

KVFKVQRIQDGKIFAAKVIKRAKLEENKYKDKFVAMLLNEYRVLSESKHKNIIQMEEIYQDHDQLVYIMEFLVGG----EVYSRLR--QVKRF--SEEVA
.|.| ... .|||.| |.||. . ...| . .. .   .| ... . .|.||... ....|.| .  .||.. ||    . .....  . ..|  ||...
CVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWEC

AEILKNLTEGLLHIHNKKIVHRDLKLENILFVNKTDNDC---KLIDFGFAE---KINYEKLESRAGTPGFLPPELFK-LGPYTEKGDIFSLGVILYCLVS
  ... . .|| ..|...|.|||||.||||.. .... .   |..|||.|.     |.. . ...|||....||. .   .|. | |..|.|.|||....
KFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC

GCSPFKGK------TYKDVLENNRRCAISYDQPVWNKIS-----------------DECKHLIRRMVEVDPKKRYACNDILKSKWM
|  ||.|.      . . ........ ...| | |. ||                 .|||..|... ..|||||. . .||...|.
GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 10066.AA RSK 46-293 29 3e-67 229.73 In-house 11-278 (278) Show / Hide 
Range on Protein: 46-293
Range on HMM: 11-278/278
Sequence Identity: 29% (81 aa)

KVFKVQRI---QDGKIFAAKVIKRAKLEENKYKDKFVAMLLNEYRVLSESK-HKNIIQMEEIYQDHDQLVYIMEFLVGGEVYSRLRQVKR---FSEEVAA
||| ....   . |.|.| ||.|.||.  ..     ..  . | ..|.... |..|..  . .|. . |  |||.. ||| . .|.. |.   |||. |.
KVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKD---TRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEAC

EILKNLTEGLLHIHNKKIVHRDLKLENILFVNKTDN--DCKLIDFGFAEK-INY--EKLESRAGTPGFLPPELFK----LGPYTEKGDIFSLGVILYCLV
... ...  . |.| ..|.|||||.||||. ... |    ||.||||. .  .   ... .  .|  ...||. |     | ...  |..||||..| . 
FYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEML

SGCSPFKG---KTYKDVLENNRRCAISYDQPVWNKISDECKHLIRRMVEVDPKKRYA-----CNDILKSKWM
.||.||.|   .. |..... ... .| . | |...|.|.|.|||.| ..||.||.       ..|....|.
TGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 10066.AA CDPK 59-293 35 2.5e-62 190.03 In-house 29-271 (271) Show / Hide 
Range on Protein: 59-293
Range on HMM: 29-271/271
Sequence Identity: 35% (88 aa)

FAAKVIKRAKLEENKYKDKFVAMLLNEYRVLSESKHKNIIQMEEIYQDHDQLVYIME--FLVGGEVYSRLRQVKRFSEEVAAEILKNLTEGLLHIHNKKI
.| |.|.  .. ....      ...||  .|..  | |||.. | ||| .    .||  .. |||   .  . ..|.|  ||.| . .   . ..|...|
VAMKIIPKSRVKDKEQ----QQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHFTEKEAAYIMRQILSAVNYCHSNNI

VHRDLKLENILFVNKTDN-----DCKLIDFGFAEKINY------EKLESRAGTPGFLPPELFKLGPYTEKGDIFSLGVILYCLVSGCSPFKGKTYKDVLE
|||||| ||||| .| |.     . |.||.| ..| .       .|.  |.|||  . ||  .   | || || |.||||| | .|  || ||. ....|
VHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIME

NNRRCAISYDQPVWNKISDECKHLIRRMVEVDPKKRYACNDILKSKWM
. . .  |...| |..||||.| |||.| ..|||||. ....|. .|.
KVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 10066.AA CAMKL 49-293 28 4.4e-62 196.87 In-house 14-297 (297) Show / Hide 
Range on Protein: 49-293
Range on HMM: 14-297/297
Sequence Identity: 28% (82 aa)

KVQRIQD----GKIFAAKVIKRAKLEENKYKDKF------VAMLLN---EYRVLSESK---HKNIIQMEEIY-------QDHDQLVYIMEFLVGGE--VY
||.  ..    |.  | |.|.. |. .. ...|        ... .   |.. ..  .   |.|||.. |..       .  .... .||   |||   .
KVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLVMEYCSGGEMDLF

SRLRQV----KRFSEEVAAEILKNLTEGLLHIHNKKIVHRDLKLENILFVNKTDNDCKLIDFGFAEKIN------YEKLESRAGTPGFLPPELFKL--GP
 ....     .|..|. |  . . . ... ..|...|||||.|.||||. .. .|  |.|||||. ..        .||. . |.| . .||.|.    |
DYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKP

YT-EKGDIFSLGVILYCLVSGCSPFKGKTY-------KDVLENNRRCAISYDQPVWNKISDECKHLIRRMVEVDPKKRYACNDILKSKWM
|   | || |.||||| .| |  ||.. ||       .  |..  .|   |  |.|...| .|..|||.| .|.|.||. . .|.. .||
YDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG--YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 10066.AA MSK 49-293 28 2e-57 192.69 In-house 17-277 (277) Show / Hide 
Range on Protein: 49-293
Range on HMM: 17-277/277
Sequence Identity: 28% (77 aa)

KVQRIQDGKIFAAKVIK------RAKLEENKYKDKFVAMLLNEYRVLSESKHKNIIQMEEIYQDHDQLVYIMEFLVGGEVYSRLRQVKRFSEEVAAEILK
|. . ..||..|.|...      ..|..|.  .   .. ..         .|.|| .  . .||   .  .||.. |||   ..|. ..|.|. ...|. 
KCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQ--------QHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDESECRMIMR

NLTEGLLHIHNKKIVHRDLKLENILFVNKTD-NDCKLIDFGFAEKINYE---KLESRAGTPGFLPPELFK-----LGPYTEKGDIFSLGVILYCLVSGCS
 |   . |.| |.|.|||||.||||| ...|    ||||||||   . .   .. |  .|  . .||. .      | | |  |..||||||| . .|..
ELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQV

PFK-----GK----TYKDVLENNRRCAISYDQPVWNKISDECKHLIRRMVEVDPKKRYACNDILKSKWM
||.     ..    . ...    ...  |..   |...| . |.||... ..|||||  .||.... | 
PFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase 10066.AA CAMK-Unique 46-293 21 1e-53 175.62 In-house 14-363 (363) Show / Hide 
Range on Protein: 46-293
Range on HMM: 14-363/363
Sequence Identity: 21% (76 aa)

KVFKVQRIQDGKIFAAKVIKRAKLEENKYKD------------KFVAM-LLNEYRVLSESKHKNIIQMEEI----YQDHD---------------QLVYI
.|.... .  ||..| |..| .. ...|.|             |   | | .| ...   .| |||. ...    ..| .                .. .
HVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIV

MEFLVGGEVYSRLRQ--------------------VKRFSE--EVAAEILKNLTEGLLHIHNKKIVHRDLKLENILFVNK--------------TDNDCK
||.. ||.... . .                      .|||    .. |   |.. . . |...|||||||||||.. .                ... |
MEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIK

LIDFGFAEKINYEKLE----SRAGTPGFLPP--------------ELFKLGPYTEKG----DIFSLGVILYCLVSGCSPFKGKTYK--------DVLENN
|.||| . ..|  | .    .. ||| .. |              |. .  .| ..     || |||||.| . .||.|| . . .          .|. 
LCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECI

RRCAI-SYDQPVWNK---ISDECKHLIRRMVEVDPKKRYACNDILKSKWM
. . . ..| ..|.    ||.| | .. .  .|||..|  .. .|.. | 
CKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 10066.AA Ciliate-E2-Unclassified 46-293 22 3.9e-53 182.66 In-house 14-352 (352) Show / Hide 
Range on Protein: 46-293
Range on HMM: 14-352/352
Sequence Identity: 22% (77 aa)

KVFKVQRIQDGKIF-----AAKVIKRA--------------KLEENKYKDKFVA---MLLNEYRVLSESKHKNIIQMEEIYQDHDQLVYIMEFLVGG---
||.|.|.....  .     . |.....              | ..|| |  ..     ....   |. ..| .|. |... || . .  .||.. ||   
KVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQ--ILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLW

--------------EVYSRLRQVKRFSEEVAA-----EILKNLTEGLLHIHNKK-IVHRDLKLENILFVNKT-DNDCKLIDFGFAEKIN-----------
              . . ...| |.|.|. |.      ... . .|| ..| |. |.|||.|.||||| |.   . .|.||||.. |..           
QYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQ

------YEKLESRAGTPGFL----PPELFKLGPYT----EKGDIFSLGVILYCLVSGCSPFKGKTYKD---------------VLENNRRCAISYDQPVW
      .... ...|||...    .||...   |     .| ||.|||||||... |  ||.......                |..|    . . .. .
KMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFP

N-----KISDECKHLIR----RMVEVDPKKRYACNDILKSKWM
.     ..|.|.|..|.    .| ...|.||.  ..||.  |.
WQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 10066.AA TyrKc 47-288 17 1.7e-11 -36.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 47-288
Range on HMM: 1-280/280
Sequence Identity: 17% (50 aa)

VFKVQRIQDG---KIFAAKV-----IKRAKLEENKYKDKFVAMLLNEYRVLSES--KHKNIIQMEEIYQDH-------DQLVYIMEFLVGGEVYSRLRQV
. . . .  |   ... ..      .|  | .        ......| |....   .|.||...  .  ..       ..|  .||.  .|   ..||  
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KR-FSEEVAAEILKNLTEGLLHIHNKKIVHRDLKLENILFVNKTDNDCKLIDFGFAEKINYE------KLESRA----GTPGFLP-----PELFKLGPYT
.. .. .   ..     .|  ..| |...||||   |.|  ..    .|  ||| . .|  .      |   |.    |. . ||     || .. | .|
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKGDIFSLGVILYCLVSGCSPFKGK----------TYKDVLENNRRCAISYDQPVWNKI-----SDECKHLIRRMVEVDPKKR---YACNDIL
.| |..| || .. . . . .               ...| . .|.    .|      .     .||   ....  . ||..|    .. ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 10066.AA Pkinase_Tyr 78-245 22 3.9e-05 18.03 Pfam 46-226 (270) Show / Hide 
Range on Protein: 78-245
Range on HMM: 46-226/270
Sequence Identity: 22% (42 aa)

FVAMLLNEYRVLSES-KHKNIIQMEEIYQ-DHDQ--LVYIMEFLVGGEVYSRLRQ----VKRFSEEVAAEILKNLTEGLLHIHNKKIVHRDLKLENILFV
. .....| .....  .|.||...  .   . ..  .  .||.  .|  .. ||.     .... .   ..     .|. . ..|...||||   |.|  
CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT

NKTDNDCKLIDFGFAEKINYEKLES-RAGTPGFLP-----PELFKLGPYTEKGDIFSLGVILYCLVSGC-SP-FKGKTYKDVLE
.  .| .|  ||| |  | |.. .  |... | ||     || .. | .|.| |. | || .. ... . .| ..| .  .|.|
E--NNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYE