21184

Species: Tetrahymena
Alias: 164.m00077, TTHERM_00923050, 1088, 21184, PreTt21184
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
21184.AA Protein None 1115 None Fasta, JSON
21184.kin_dom Protein Kinase Domain None 184 None Fasta, JSON
21184.NA RNA None 3348 None Fasta, JSON

Protein domain

Protein domains of 21184.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 21184.AA Ciliate-E1 340-514 27 6e-43 137.57 In-house 1-202 (202) Show / Hide
Range on Protein: 340-514
Range on HMM: 1-202/202
Sequence Identity: 27% (55 aa)

INSGGEADILEC-------RSKDGIFVLRFLFYKNEKNKEEIEKEYKIISSIKKQFNLTSQKDKIDIPDSNLIIILTDFYQQSLHEYLT-----------
| .|.......        ...  .....  .|. ... .||...||| . .||....    | |.| .....||.......||..||.           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

-NSLNKFDQDTFVSFIYDMIFGLIELRYYNIQHFDIKPANILLDTNLKLYFNDFGLSN--KLKYGESFVPLGHTSAFSPQEQQ-------DYQQIDNYQS
 .  |.|... ... |...|.|||||..||| |.||||.||| . . .. ..|||.|   |..  .. .  |.|. ..|.||        ...|..||.|
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DIF
||.
DIY

Kinase 21184.AA Ciliate-B2 336-517 30 6.4e-35 79.49 In-house 3-197 (197) Show / Hide
Range on Protein: 336-517
Range on HMM: 3-197/197
Sequence Identity: 30% (59 aa)

ITKFINSGGEADILECRSKDGIF-----VLRFLFYKNEKNKEEIEKEYKIISSIKKQFNLTSQKDKIDIPDSNLIIILTDFYQQSLHEYLT---NSLNKF
..|.||.||.  | |   |  |.     ... .| | . .||||..|.||...  .. |     | | | ...  .. ..  . || . |        .|
LCKYINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMFEYNINVVKYIDHIQI-NETIDVLIMEKCECSLKQELQKIQKQQKCF

DQDTFVSFIYDMIFGLIELRYYNIQHFDIKPANILLDTNLKLYFNDFGLSNKLKYGESFVPLGHTSAFSPQEQQDYQ------QIDNYQSDIFSLG
 .  ..  |...| |||..| ||| | ||||.|||.  | .  . ||| |   |        |.| .. . || .           ..||||.|.|
NNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG

S_TKc 21184.AA S_TKc 334-571 18 3.7e-12 1.45 SMART 1-231 (231) Show / Hide
Range on Protein: 334-571
Range on HMM: 1-231/231
Sequence Identity: 18% (49 aa)

LEITKFINSGGEADILECRSKD--GIFVLRFLFYKNEKNKEEIEKEYKIISSIKKQFNLTSQKDKIDIPDSNLIIILTDFYQQ---SLHEYLTNSLNK--
 || . | .|. .    || |.   |. .  .        | |..| .| ..  .  |.   .| ..    . . . ...  .   .|..|. .   .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDQDTFVSFIYDMIFGLIELRYYNIQHFDIKPANILLDTNLKLYFNDFGLSNKLKYGESFVPLGHTSAFSPQ----EQQDYQQIDNYQSDIFSLGKT
   |.  .  ...| .. .|  .   .| | |.||.|||||.   .   ||||. .|          .|   .|     |     . .   .|. |.| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

FEVVMK---AFSKQNINLYNQQQKFFDNFKNLIVLMTKKEPQDRIKCDELLL--------RFT
.   .     |. |   ....     . .|..|  . .|.|..|. . |.|          . 
LYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 21184.AA Ciliate-E3 376-524 27 5.3e-10 27.67 In-house 51-202 (202) Show / Hide
Range on Protein: 376-524
Range on HMM: 51-202/202
Sequence Identity: 27% (43 aa)

KEYKIISSIKKQFNLTSQKDKIDIPDSNLIIILTDFYQQSLHEYLTNSLNKFDQDTFVSFIYDMIFGLIELRYYNIQHFDIKPANILLDTNL---KLYFN
.| .  ..|. |. .  ..   |    .. |.       .| .|.  ..||  . .   .|. .| |.|..   || | |||| |||.|.|.    . . 
QEFQNCQQINSQNVVKCHDQYYDQQNKMIFIVQEYCSNGDLYHYIK-QQNKTQNIIYDICIQ-IIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKIC

DFGLSNKLKYGE---SFVPLGHTSAFSPQEQQDYQQIDNYQSDIFSLGKTFEVVM
|||.| .|.      .    | |. ... || |.||| .  ||. |.|  |  . 
DFGESKQLRKNKGHTHTQYQGWTPFYAAPEQNDQQQISK-ESDYYSVGAVFCQLC

Kinase 21184.AA Ciliate-E5 450-482 54 8e-09 24.63 In-house 123-155 (271) Show / Hide
Range on Protein: 450-482
Range on HMM: 123-155/271
Sequence Identity: 54% (18 aa)

NIQHFDIKPANILLDTNLKLYFNDFGLSNKLKY
|| | |||||||||  ..|  ..|.|.| |.|.
NIIHLDIKPANILLGYDNKWKYIDMGISRKFKH

Kinase 21184.AA Ciliate-E2 401-517 19 1.5e-08 25.5 In-house 105-283 (365) Show / Hide
Range on Protein: 401-517
Range on HMM: 105-283/365
Sequence Identity: 19% (36 aa)

DSNLIIILTDFYQQ-SLHEYLTNS-LN---------KFDQDTFVSFIYDMIF---------------GLIELRYYN-IQHFDIKPANILLDTNLKLYFND
| | | . ....|. .| .|. |. ..         .|.      ...  .                .| .|   | | | |||| |||.     .   |
DDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIID

FGLSNKLKYGES---------FVPLGH------------------------TSAFSPQEQQDYQQIDN--------YQSDIFSLG
|||| |..  .            .  .                        |  . . |   ....||        |..||.|||
FGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG

Kinase 21184.AA SAK 416-481 28 2.4e-08 24.24 In-house 86-151 (254) Show / Hide
Range on Protein: 416-481
Range on HMM: 86-151/254
Sequence Identity: 28% (19 aa)

LHEYLTNSLNKFDQDTFVSFIYDMIFGLIELRYYNIQHFDIKPANILLDTNLKLYFNDFGLSNKLK
.| |. . .  |  .   .|. ... |.. |   .| | |.  .||||  ....   ||||  .||
MHRYMKHRMRPFTEEEARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLK

Kinase 21184.AA ULK 425-469 27 4.2e-08 24.46 In-house 125-183 (329) Show / Hide
Range on Protein: 425-469
Range on HMM: 125-183/329
Sequence Identity: 27% (16 aa)

NKFDQDTFVSFIYDMIFGLIELRYYNIQHFDIKPANILLDTN--------------LKL
... ..  ..|... . |. ||.  || | ||||.|||.. .              ||.
KRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKI

Kinase 21184.AA Ciliate-A1 425-480 31 5e-08 23.36 In-house 95-151 (301) Show / Hide
Range on Protein: 425-480
Range on HMM: 95-151/301
Sequence Identity: 31% (18 aa)

NK-FDQDTFVSFIYDMIFGLIELRYYNIQHFDIKPANILLDTNLKLYFNDFGLSNKL
|.    .  . . | .| |.. .   || | |.|| |||.    |  . |.|.|  |
NDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLGMSKQL

Kinase 21184.AA ULK 425-469 27 5.5e-08 24.48 In-house 121-179 (324) Show / Hide
Range on Protein: 425-469
Range on HMM: 121-179/324
Sequence Identity: 27% (16 aa)

NKFDQDTFVSFIYDMIFGLIELRYYNIQHFDIKPANILLDTN--------------LKL
... ..  ..|... . |. ||.  || | ||||.|||.  .              ||.
KRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKI

Kinase 21184.AA RAN 451-482 51 1.9e-07 20.93 In-house 170-202 (324) Show / Hide
Range on Protein: 451-482
Range on HMM: 170-202/324
Sequence Identity: 51% (17 aa)

IQHFDIKPANILLD-TNLKLYFNDFGLSNKLKY
| | |||| |||.| ..   |  |.||| . ||
IYHCDIKPENILIDGIDWNIYLCDWGLSTTDKY

Kinase 21184.AA Ciliate-A1 542-573 28 0.093205 1.68 In-house 270-301 (301) Show / Hide
Range on Protein: 542-573
Range on HMM: 270-301/301
Sequence Identity: 28% (9 aa)

FDNFKNLIVLMTKKEPQDRIKCDELLLRFTGF
|    |||  |  .||. |.. ....     |
FEELQNLIFKMMQYEPNNRCSLQQCIDCLYIF

Kinase 21184.AA ULK 529-567 26 0.139263 1.46 In-house 279-319 (324) Show / Hide
Range on Protein: 529-567
Range on HMM: 279-319/324
Sequence Identity: 26% (11 aa)

KQNINLYN--QQQKFFDNFKNLIVLMTKKEPQDRIKCDELL
.|.|. ..  ...|. ...|.||  | .... |||  .|..
NQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIF

Kinase 21184.AA ULK 504-567 20 0.270315 0.38 In-house 230-324 (329) Show / Hide
Range on Protein: 504-567
Range on HMM: 230-324/329
Sequence Identity: 20% (20 aa)

QQIDNYQSDIFSL---------GKTF---EVVMKAFSKQNINLYNQ----------QQKFFD----------NFKNLIVLMTKKEPQDRIKCDELL
.. ..| .||.||         ||.       .. . .....|.|.          |.  |.          ..|.||  | .... |||  .||.
KPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELF

TPR 21184.AA TPR 660-693 14 0.975419 0.68 SMART 1-34 (34) Show / Hide
Range on Protein: 660-693
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

LFGLYCIGFAYYIQSKYYQSAKILNTCFQIGIQL
   .|..| .|| . .| .  . .. . ..  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 21184.AA TPR_2 660-693 17 40.657978 0.96 Pfam 1-34 (34) Show / Hide
Range on Protein: 660-693
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

LFGLYCIGFAYYIQSKYYQSAKILNTCFQIGIQL
  ..|..| .|| | .| . .. .. . ..  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_2 21184.AA TPR_2 701-734 26 0.016539 12.96 Pfam 1-34 (34) Show / Hide
Range on Protein: 701-734
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

IDLANAIGACYINLGLYKEAYDLYKASIKQLDKI
 .. ...| ||...| |.|| ..|....|   . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR 21184.AA TPR 701-734 23 0.049598 12.05 SMART 1-34 (34) Show / Hide
Range on Protein: 701-734
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

IDLANAIGACYINLGLYKEAYDLYKASIKQLDKI
..  . .| || ..| |.|| . |. ...   . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 21184.AA TPR_1 701-734 23 0.089614 10.18 Pfam 1-34 (34) Show / Hide
Range on Protein: 701-734
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

IDLANAIGACYINLGLYKEAYDLYKASIKQLDKI
 .  . .|.|| ..| |.|| . |.  ..   . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR 21184.AA TPR 744-777 20 0.000367 21.07 SMART 1-34 (34) Show / Hide
Range on Protein: 744-777
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

CQICSNFAECLLTAGKLDEAEKLYNQSIKIFKEL
 ....| ..|..  |..|||.. |......  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 21184.AA TPR_2 744-777 23 0.002061 16.16 Pfam 1-34 (34) Show / Hide
Range on Protein: 744-777
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

CQICSNFAECLLTAGKLDEAEKLYNQSIKIFKEL
  .. | ..|.. .|..|||...|....|.. . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_1 21184.AA TPR_1 744-777 20 0.029585 11.86 Pfam 1-34 (34) Show / Hide
Range on Protein: 744-777
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

CQICSNFAECLLTAGKLDEAEKLYNQSIKIFKEL
 ....| . |..  |..|||.. |.. ...  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_1 21184.AA TPR_1 786-819 17 2.4e-05 22.66 Pfam 1-34 (34) Show / Hide
Range on Protein: 786-819
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

SQILNNIATYQNDQKKYQDALQNYTQCLQVKRNL
.....|..  .  ...|..|.. | ..|.. .| 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR 21184.AA TPR 786-819 17 2.8e-05 24.79 SMART 1-34 (34) Show / Hide
Range on Protein: 786-819
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

SQILNNIATYQNDQKKYQDALQNYTQCLQVKRNL
.....|..     ...|..|.. |...|.. .| 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 21184.AA TPR_2 786-819 20 0.223341 8.96 Pfam 1-34 (34) Show / Hide
Range on Protein: 786-819
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

SQILNNIATYQNDQKKYQDALQNYTQCLQVKRNL
  ...|..     |..|..|.. | ..|.   | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_2 21184.AA TPR_2 898-931 17 0.001729 16.43 Pfam 1-34 (34) Show / Hide
Range on Protein: 898-931
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

SKFQNSLATLYMAKGEYEQALNQMNEVLQMNELI
 .  . |. .|...|.|..|.. ....|. ..  
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR 21184.AA TPR 898-931 17 0.027432 14.31 SMART 1-34 (34) Show / Hide
Range on Protein: 898-931
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

SKFQNSLATLYMAKGEYEQALNQMNEVLQMNELI
..  . |. .|...|.|..|..  ...|....  
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 21184.AA TPR_1 898-929 21 0.12381 9.69 Pfam 1-32 (34) Show / Hide
Range on Protein: 898-929
Range on HMM: 1-32/34
Sequence Identity: 21% (7 aa)

SKFQNSLATLYMAKGEYEQALNQMNEVLQMNE
..  . |. .|...|.|..|.   ...|..|.
AEAWYNLGNCYYKMGNYDEAIECYQKALELNP

TPR 21184.AA TPR 938-971 23 0.000143 22.43 SMART 1-34 (34) Show / Hide
Range on Protein: 938-971
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ALISFNLADMYLQIQQYENAKKYCLQAINILQQN
| . .||. .|..  .|. | ... .|. .  .|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 21184.AA TPR_2 938-971 26 0.000165 20.04 Pfam 1-34 (34) Show / Hide
Range on Protein: 938-971
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

ALISFNLADMYLQIQQYENAKKYCLQAINILQQN
| . .||.. |.. ..|. |..|. .|. .  .|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_1 21184.AA TPR_1 938-971 23 0.000244 19.13 Pfam 1-34 (34) Show / Hide
Range on Protein: 938-971
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ALISFNLADMYLQIQQYENAKKYCLQAINILQQN
| . .||.  |.. ..|. | ... .|. .  .|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR 21184.AA TPR 980-1012 23 1.033269 0.46 SMART 1-34 (34) Show / Hide
Range on Protein: 980-1012
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

SVALNSYGKILEIL-KSNEAIDYLIKAVEIKEKY
. |..  | ... . . .|||... ||.|. ...
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 21184.AA TPR_1 996-1012 35 2.270622 5.28 Pfam 18-34 (34) Show / Hide
Range on Protein: 996-1012
Range on HMM: 18-34/34
Sequence Identity: 35% (6 aa)

NEAIDYLIKAVEIKEKY
.|||... ||.|. ...
DEAIECYQKALELNPNN

TPR_2 21184.AA TPR_2 997-1012 37 60.813229 0.34 Pfam 19-34 (34) Show / Hide
Range on Protein: 997-1012
Range on HMM: 19-34/34
Sequence Identity: 37% (6 aa)

EAIDYLIKAVEIKEKY
|||.|. ||... ...
EAIEYYEKALKLDPNN