Gene 1932 (Tetrahymena)
1932
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 1932.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 1932.AA | Ciliate-E1 | 513-686 | 19 | 4.2e-23 | 72.28 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 513-686 Range on HMM: 1-202/202 Sequence Identity: 19% (40 aa) INSGGEADIFTHTYDESI---AYRVIKLDEDE-DLNEQLLELYSIKELQEQNILDLNTSHLIEDKI-NDTKYIIHVMQKCQMSLSDEIL----------- | .|.....| ..... . .| . .. . |... |.. ...... . .. .|. .. . . .| ....|..|| |.. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC --SKKVFSLKEILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQ-----QVNFIDPFCGYKMYTPGFKPS------KQKQSLPFYH .. |. ..... | ... || |.|. |.|.|||| |||. ...||...||| |. | . .. .. ..| | . ...| . QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS DIY ||| DIY |
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| Kinase | 1932.AA | Ciliate-B2 | 507-651 | 29 | 1.1e-20 | 45.27 | In-house | 1-151 (197) | Show / Hide |
Range on Protein: 507-651 Range on HMM: 1-151/197 Sequence Identity: 29% (45 aa) FNLGDHINSGGEADIFTHTYDES-IAYR--VIKLDED-EDLNEQLLEL-YSIKELQEQNILDLNTSHLIEDKINDTKYIIHVMQKCQMSLSDEIL----S . |.. ||.||. |. .| |. ..| .. .| ... .. ..| . |.|| . | .|| | .. .|.||. || .|. YYLCKYINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMFEYNINVVKYIDHI--QINETIDVL-IMEKCECSLKQELQKIQKQ KKVFSLKEILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGAS .| | . ... | . || .| . | | |||| |||. .||...||| | QKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGIS |
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| Kinase | 1932.AA | Ciliate-C6 | 598-655 | 43 | 7.2e-13 | 41.95 | In-house | 129-188 (306) | Show / Hide |
Range on Protein: 598-655 Range on HMM: 129-188/306 Sequence Identity: 43% (26 aa) KKVFSLKEILRFISTAFHLLIVLRQ-KYIYHSDIKPGNILKIDD-NNYKLSDFGASQQVN .. |. .||. | . .| .. | | |||| ||| .|| |||.|||||..|| . YEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLF |
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| Kinase | 1932.AA | Ciliate-E3 | 617-653 | 51 | 2.1e-08 | 22.63 | In-house | 116-155 (202) | Show / Hide |
Range on Protein: 617-653 Range on HMM: 116-155/202 Sequence Identity: 51% (21 aa) LIVLRQKYIYHSDIKPGNILKIDDNN----YKLSDFGASQQ .| . .| | |||||| ||| .| || | .|||.| | MIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGESKQ |
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| Kinase | 1932.AA | S_TKc | 507-757 | 13 | 1e-06 | -78.25 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 507-757
Range on HMM: 1-231/231
Sequence Identity: 13% (41 aa)
FNLGDHINSGGEADIFTHTY---DESIAYRVIKLDEDEDLNEQLLELYSIKELQEQNILDLNTSHLIEDKINDTKYIIHVMQKCQM---SLSDEILSKKV
. ....| .|. . . . .. | .|| . . |. |. . || | . ... || | .| | | ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR
------FSLKEILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPFCG---------YKMYTPGFKPSKQKQSLPFYH--
|. .. ... . | . .. | | |.|| ||| .|. . |..||| . |. . ||| .. .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENIL-LDE-HIKICDFGLARQL---TTFCGTPWYMAPEVL----------------GYGKCK
-DIYSFGKTIQKLLM-----QLENHSEISKCLNKFIDEEICKDDENSIKVDCFQQPKKFINILMNFINQE-----VIDTFLE--------EYL
|..|.| .. .| . .. . ..| .. ....... . . . |. ...
CDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 1932.AA | LKB | 625-660 | 41 | 1e-06 | 15.75 | In-house | 125-160 (265) | Show / Hide |
Range on Protein: 625-660 Range on HMM: 125-160/265 Sequence Identity: 41% (15 aa) IYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPF . | ||||||.| || |..||| |.. .. VVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRD |
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| Kinase | 1932.AA | TAO | 583-662 | 35 | 3e-06 | 16.06 | In-house | 77-157 (254) | Show / Hide |
Range on Protein: 583-662 Range on HMM: 77-157/254 Sequence Identity: 35% (29 aa) VMQKCQMSLSDEI-LSKKVFSLKEILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPFCG || | | || . || . || . | . | | . | ||| |||| .. ||.|||. |. . | | VMEYCLGSASDILDVHKKPMQEVEIAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPANSFVG |
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| Kinase | 1932.AA | RAN | 625-649 | 62 | 4e-06 | 16.5 | In-house | 170-195 (324) | Show / Hide |
Range on Protein: 625-649 Range on HMM: 170-195/324 Sequence Identity: 62% (17 aa) IYHSDIKPGNILKID--DNNYKLSDFG ||| |||| ||| || | | .| |.| IYHCDIKPENIL-IDGIDWNIYLCDWG |
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| Kinase | 1932.AA | Ciliate-E8 | 625-651 | 48 | 5e-06 | 14.91 | In-house | 110-138 (138) | Show / Hide |
Range on Protein: 625-651 Range on HMM: 110-138/138 Sequence Identity: 48% (14 aa) IYHSDIKPGNIL-KI-DDNNYKLSDFGAS | |.|.| ||| . || . |. ||| | IIHCDFKLNNILVQRNDDTKIKIIDFGFS |
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| Kinase | 1932.AA | MOK | 625-663 | 43 | 5e-06 | 14.29 | In-house | 121-158 (283) | Show / Hide |
Range on Protein: 625-663 Range on HMM: 121-158/283 Sequence Identity: 43% (17 aa) IYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPFCGY |.| |.|| ||| | . ||.|||. | |. | IFHRDVKPENIL-IKQDHLKLADFGSCRSVYSKQPYTEY |
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| Kinase | 1932.AA | CAMKK | 627-654 | 41 | 6e-06 | 14.37 | In-house | 219-249 (396) | Show / Hide |
Range on Protein: 627-654 Range on HMM: 219-249/396 Sequence Identity: 41% (13 aa) HSDIKPGNILKIDDN---NYKLSDFGASQQV | |||| ||| ... . |..||| |... HRDIKPQNILIDEEGCGEHVKIADFGVSHIF |
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