Gene 1931 (Tetrahymena)
1931
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 1931.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 1931.AA | Ciliate-B2 | 366-434 | 36 | 3.7e-22 | 48.81 | In-house | 79-151 (197) | Show / Hide |
Range on Protein: 366-434 Range on HMM: 79-151/197 Sequence Identity: 36% (27 aa) IIQKCQMSLKDEIS----SKKVYSLKETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKTDDNNYKLSDFGAS |..||. |||.|. .| . . .. | . || .| . | | |||| |||.. .||...||| | IMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGIS |
|||||||||
| Kinase | 1931.AA | Ciliate-E1 | 296-469 | 21 | 7.6e-20 | 61.58 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 296-469 Range on HMM: 1-202/202 Sequence Identity: 21% (44 aa) IDSGLEADIFAN--QNDD-NIVYRVIKLDRDQNLTKQGREILRFQELEEQNILNITSSHLIVDKINKTDY--IIQIIQKCQMSLKDEIS----------- | .| ....| ||. | |. .| . ... . .... . . .. . . ... |.| | . .. .|.|...|..||||... IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC --SKKVYSLKETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKTDDNNYKLSDFGASQ-----QVDFINPFCDYEMYTEGYTPK------NRDKNLPFYH .. .. .. .. | ... || |.|. |.|.|||| |||.....||...||| |. | . .. .. ..| . . |.... . QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS DIY ||| DIY |
|||||||||
| Kinase | 1931.AA | Ciliate-C6 | 365-438 | 34 | 6e-12 | 38.65 | In-house | 102-188 (306) | Show / Hide |
Range on Protein: 365-438 Range on HMM: 102-188/306 Sequence Identity: 34% (30 aa) QIIQKCQMS-----LKDEISS------KKVYSLKETLKFISTAFHLLIVLRQ-KYIYHSDIKPGNILKTDD-NNYKLSDFGASQQVD ..||. | .| ||. .. .. .| ..| . .| .. | | |||| ||| || |||.|||||..|| . DCIQMKQANVNNFYFKQEINIFSFNYKYEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLF |
|||||||||
| Kinase | 1931.AA | Ciliate-A1 | 408-445 | 42 | 2.8e-10 | 31.14 | In-house | 122-159 (301) | Show / Hide |
Range on Protein: 408-445 Range on HMM: 122-159/301 Sequence Identity: 42% (16 aa) IYHSDIKPGNILKTDDNNYKLSDFGASQQVDFINPFCD | |.|.||.||| .|. .|. |.| |.| . . || ILHRDLKPQNILIHFDDKWKICDLGMSKQLEQNQDCCD |
|||||||||
| Kinase | 1931.AA | LKB | 408-443 | 44 | 1.4e-08 | 21.65 | In-house | 125-160 (265) | Show / Hide |
Range on Protein: 408-443 Range on HMM: 125-160/265 Sequence Identity: 44% (16 aa) IYHSDIKPGNILKTDDNNYKLSDFGASQQVDFINPF . | ||||||.| | || |..||| |.. .. VVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRD |
|||||||||
| Kinase | 1931.AA | Ciliate-A5 | 399-432 | 41 | 1.1e-07 | 22.83 | In-house | 111-144 (275) | Show / Hide |
Range on Protein: 399-432 Range on HMM: 111-144/275 Sequence Identity: 41% (14 aa) LLIVLRQKYIYHSDIKPGNILKTDDNNYKLSDFG .. .|.|. |.| ||.| ||. |.|. .|| |.. VCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMN |
|||||||||
| Kinase | 1931.AA | CAMKK | 410-438 | 40 | 1.3e-07 | 19.76 | In-house | 219-250 (396) | Show / Hide |
Range on Protein: 410-438 Range on HMM: 219-250/396 Sequence Identity: 40% (13 aa) HSDIKPGNILKTDDN---NYKLSDFGASQQVD | |||| ||| .... . |..||| |.... HRDIKPQNILIDEEGCGEHVKIADFGVSHIFE |
|||||||||
| Kinase | 1931.AA | Ciliate-E3 | 385-436 | 37 | 4.6e-07 | 18.39 | In-house | 101-155 (202) | Show / Hide |
Range on Protein: 385-436 Range on HMM: 101-155/202 Sequence Identity: 37% (21 aa) SLKETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKTDDNN----YKLSDFGASQQ .. .... . . .| . .| | |||||| ||| | || | .|||.| | TQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGESKQ |
|||||||||
| Kinase | 1931.AA | STE11 | 410-442 | 44 | 2e-06 | 19.91 | In-house | 139-172 (303) | Show / Hide |
Range on Protein: 410-442 Range on HMM: 139-172/303 Sequence Identity: 44% (15 aa) HSDIKPGNILKTDDNN-YKLSDFGASQQVDFINP | |||. ||| |.| ||.|||.. .. |.. HRDIKGANILLDSDGNVCKLADFGCAKRLAWICT |
|||||||||
| Kinase | 1931.AA | Meta | 410-436 | 51 | 2e-06 | 14.52 | In-house | 146-172 (287) | Show / Hide |
Range on Protein: 410-436 Range on HMM: 146-172/287 Sequence Identity: 51% (14 aa) HSDIKPGNILKTDDNNYKLSDFGASQQ | ||||.| | .||. | ||| | . HRDIKPSNLLLNDDGHVKIADFGVSNE |
|||||||||
| S_TKc | 1931.AA | S_TKc | 290-540 | 13 | 3e-06 | -84.29 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 290-540 Range on HMM: 1-231/231 Sequence Identity: 13% (40 aa) FKLNDHIDSGLEADIFANQNDDNIVYRVIKLDRDQNLTKQGREILRFQELEEQNILNITSSHLIVDKINKTDYIIQIIQKCQM---SLKDEISSKKV--- ... ..| .| . . .. . . || . . ... ..||. || .. . |.. . | .|.| | ... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK---HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---YSLKETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKTDDNNYKLSDFGASQQVDFINPFC--------------D------------YEMYTEGYT .. .. ... . | . .. | | |.|| ||| .. . |..||| . |. . || |||.. ||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLC-GYP PKNRDKNLPFYHDIYSIGKTIQKLLMQLENHSEIYDCLNKFIDEKICKDDENSIYIDCFKLPRKFINILMKF------TNDEVIE----VFLEEYL | . ....|.. . . ||. .... | |. . . . ... PFP------------QMQMMFKKIG---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
| Kinase | 1931.AA | Pkinase | 408-434 | 38 | 0.000948 | 14.34 | Pfam | 129-159 (293) | Show / Hide |
Range on Protein: 408-434 Range on HMM: 129-159/293 Sequence Identity: 38% (12 aa) IYHSDIKPGNILKTDDNNY----KLSDFGAS | | |.|| ||| .... |..||| . IIHRDLKPENILIDNNGHIDACVKICDFGLA |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1311-1338 | 28 | 0.035979 | 8.73 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1311-1338 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NTTKLNLCLRENHIGSQGAEYISNAIKH |.. . | |. |..| |. .....|| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1345-1368 | 29 | 0.039808 | 8.42 | SMART | 5-28 (28) | Show / Hide |
Range on Protein: 1345-1368 Range on HMM: 5-28/28 Sequence Identity: 29% (7 aa) LDIDLSKNGIKDKGAQSIAEALQY . ..|| |.. |.|.. ..|.|. RELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1371-1398 | 28 | 0.05168 | 7.62 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1371-1398 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NITTFNLSLRNNNIGVESIKNIVNSLEM | . |.|.||..| | .. . ..|. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1401-1428 | 39 | 0.00982 | 12.71 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1401-1428 Range on HMM: 1-28/28 Sequence Identity: 39% (11 aa) KLSQLHLDLSENDIKDEGANILVRSLKK . | . |.|| |.. |||. | .|| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1431-1458 | 28 | 0.021348 | 10.33 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1431-1458 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NMAYLKLVLNKNGISSEGAMNISNALKR |. ..| |. |.. ||.. ....|| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1465-1488 | 29 | 0.464285 | 0.89 | SMART | 5-28 (28) | Show / Hide |
Range on Protein: 1465-1488 Range on HMM: 5-28/28 Sequence Identity: 29% (7 aa) LNIDFTNNKIFDEGAKAIANSLTK . .. |||. |||.......|. RELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1491-1518 | 28 | 0.003914 | 15.53 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1491-1518 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NLTLLNLNIYGNKITSEGISSITNALEK | .|. |.. .||.. ||. . ..|. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1551-1578 | 17 | 0.245781 | 2.84 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1551-1578 Range on HMM: 1-28/28 Sequence Identity: 17% (5 aa) NITQLILILEANQITYKGAQEIASAIEK | . . | |. | .. .|......... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 1931.AA | LRR_RI | 1581-1608 | 25 | 0.074962 | 6.48 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1581-1608 Range on HMM: 1-28/28 Sequence Identity: 25% (7 aa) KISNLTLNLNSNQIQDEGAQSISNTMEK . | ..|.|..| . |||.. .... . NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||