18323

Species: Tetrahymena
Alias: 296.m00011, PreTt18323, 18323, TTHERM_01259660, 756
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
18323.AA Protein None 779 None Fasta, JSON
18323.kin_dom Protein Kinase Domain None 118 None Fasta, JSON
18323.NA RNA None 2340 None Fasta, JSON

Protein domain

Protein domains of 18323.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 18323.AA Ciliate-E1 308-481 21 7.7e-25 78.0 In-house 1-202 (202) Show / Hide
Range on Protein: 308-481
Range on HMM: 1-202/202
Sequence Identity: 21% (43 aa)

INSGGEADIFTH---QYD-ESIAYRVIKLDGDEDLNEQLKELYSVKELQEQNILNLNNSHLVEYKV-EDTKYIIHVMQKCQMSLQDEIS-----------
| .|.....|     ..  ...|  .|.. . .. |....|..  .....  . . .   ...|.  .. . .| ....|..||.|...           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

--SKKVFSLRETLRFISTAFHVLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPY-CDYEMHTPGYIPQNQ----------TKSLPFYH
   .. |.  . .. |  ... || |.|. |.|.|||| |||. ...||...||| |.. .  . . |.|. .|  | |..|          ..   .  
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DIY
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DIY

Kinase 18323.AA Ciliate-B2 378-484 30 1.3e-22 49.91 In-house 79-197 (197) Show / Hide
Range on Protein: 378-484
Range on HMM: 79-197/197
Sequence Identity: 30% (36 aa)

VMQKCQMSLQDEIS----SKKVFSLRETLRFISTAFHVLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPYCDYEMHTPGYIPQNQTKS
.|.||. ||..|.      .| |     .. |   .  || .| . | | |||| |||.   .||...||| |   .  .       .|  | .  | . 
IMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKK-DNQQIKIKGFTKKYASPEQMEC

L---------PFYHDIYSFG
           |  |||| |
DHNQTFVTNIDFQSDIYSMG

Kinase 18323.AA Ciliate-C6 411-450 52 2.2e-11 36.58 In-house 147-188 (306) Show / Hide
Range on Protein: 411-450
Range on HMM: 147-188/306
Sequence Identity: 52% (22 aa)

VLIVLRQ-KYIYHSDIKPGNILKIDD-NNYKLSDFGASQQVN
.|  ..    | | |||| ||| .|| |||.|||||..|| .
TLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLF

Kinase 18323.AA Ciliate-A1 420-457 42 6.7e-09 26.36 In-house 122-159 (301) Show / Hide
Range on Protein: 420-457
Range on HMM: 122-159/301
Sequence Identity: 42% (16 aa)

IYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPYCD
| |.|.||.|||  .|. .|. |.| |.|  .    ||
ILHRDLKPQNILIHFDDKWKICDLGMSKQLEQNQDCCD

S_TKc 18323.AA S_TKc 302-552 14 1.1e-08 -49.46 SMART 1-231 (231) Show / Hide
Range on Protein: 302-552
Range on HMM: 1-231/231
Sequence Identity: 14% (40 aa)

FQLGDHINSGGEADIFTHQY---DESIAYRVIKLDGDEDLNEQLKELYSVKELQEQNILNLNNSHLVEYKVEDTKYIIHVMQKCQM---SLQDEISSKKV
......| .|. .  .  .    ..  |  .||       .  ..|.   |. .  || .|  .          ...  ||  |     .| | | ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR

------FSLRETLRFISTAFHVLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPYCDYEMHTPGYIPQNQTKSLPFYH---DIYSFGKT
      |.  .. ...   .  |  . .. | | |.|| ||| .|. . |..||| . |.       .    || |..       .. .   |..|.| .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENIL-LDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

IQKLLM-----QLENHSEISDCLNQFIKEEICKDDKNSINVDCLEQPRKFINILMNFVNYEVI-----EVFL-------EEYL
.  .|      .     ..   ...                     .. .......  ...       |..         ...
LYEMLCGYPPFP-----QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF

Kinase 18323.AA Ciliate-E3 412-448 51 2.1e-08 22.63 In-house 116-155 (202) Show / Hide
Range on Protein: 412-448
Range on HMM: 116-155/202
Sequence Identity: 51% (21 aa)

LIVLRQKYIYHSDIKPGNILKIDDNN----YKLSDFGASQQ
.| . .| | |||||| ||| .| ||     | .|||.| |
MIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGESKQ

Kinase 18323.AA MOK 420-458 46 1e-06 16.19 In-house 121-158 (283) Show / Hide
Range on Protein: 420-458
Range on HMM: 121-158/283
Sequence Identity: 46% (18 aa)

IYHSDIKPGNILKIDDNNYKLSDFGASQQVNFIDPYCDY
|.| |.|| ||| | .   ||.|||.   |    || .|
IFHRDVKPENIL-IKQDHLKLADFGSCRSVYSKQPYTEY

Kinase 18323.AA Ciliate-A5 411-444 41 2e-06 18.33 In-house 111-144 (275) Show / Hide
Range on Protein: 411-444
Range on HMM: 111-144/275
Sequence Identity: 41% (14 aa)

VLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFG
|. .|.|. |.| ||.| ||.  .|. .|| |..
VCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMN

Kinase 18323.AA LKB 420-444 56 2e-06 15.1 In-house 125-149 (265) Show / Hide
Range on Protein: 420-444
Range on HMM: 125-149/265
Sequence Identity: 56% (14 aa)

IYHSDIKPGNILKIDDNNYKLSDFG
. | ||||||.|   ||  |..|||
VVHKDIKPGNLLLTHDNTLKICDFG

Kinase 18323.AA RAN 420-444 62 4e-06 16.5 In-house 170-195 (324) Show / Hide
Range on Protein: 420-444
Range on HMM: 170-195/324
Sequence Identity: 62% (17 aa)

IYHSDIKPGNILKID--DNNYKLSDFG
||| |||| ||| ||  | | .| |.|
IYHCDIKPENIL-IDGIDWNIYLCDWG

Kinase 18323.AA Ciliate-E8 420-446 48 5e-06 14.91 In-house 110-138 (138) Show / Hide
Range on Protein: 420-446
Range on HMM: 110-138/138
Sequence Identity: 48% (14 aa)

IYHSDIKPGNIL-KI-DDNNYKLSDFGAS
| |.|.|  ||| .  || . |. ||| |
IIHCDFKLNNILVQRNDDTKIKIIDFGFS