18320

Species: Tetrahymena
Alias: 18320, 296.m00008, PreTt18320, TTHERM_01257650, 1038
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
18320.AA Protein None 645 None Fasta, JSON
18320.kin_dom Protein Kinase Domain None 27 None Fasta, JSON
18320.NA RNA None 1938 None Fasta, JSON

Protein domain

Protein domains of 18320.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 18320.AA Ciliate-E1 297-470 19 1.5e-21 67.15 In-house 1-202 (202) Show / Hide
Range on Protein: 297-470
Range on HMM: 1-202/202
Sequence Identity: 19% (40 aa)

INSGGEADIFTN--QNYD-YIVYRVIKLNGDEDLRKQEKELLRLQE-LQEQNIFNIDSSHLIEDKI-NHTKYIIYVMQKCKMSLQDEIL-----------
| .|.....|    ||.  . |. .| .  . .   .. .... .  ...  .... .  .|. ..    . .| ....|..||.|..            
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

--SKKVFSLRETLKFISTSFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGASQ-----YVDFIDPFCDFEMYTPSFTPQ------KKEKNLPFYH
   .. |.  . .. |   .. || |.|. |.|.|||| |||. ...||...||| |.       . .. ..  ..| |.   .      .|...  .  
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DIY
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DIY

Kinase 18320.AA Ciliate-B2 291-435 26 3.8e-18 39.17 In-house 1-151 (197) Show / Hide
Range on Protein: 291-435
Range on HMM: 1-151/197
Sequence Identity: 26% (41 aa)

FKLGDHINSGGEADIFTNQ------NYDYIVYRVIKL--NGDEDLRKQEKELLRLQELQEQNIFNIDSSHLIEDKINHTKYIIYVMQKCKMSLQDEIL--
. |.. ||.||.  |.          |  .....     ..|..   .| . . . | ... .  ||.   |. .|.     . .|.||. ||..|.   
YYLCKYINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMFEYNINVVKYIDHIQ-INETID-----VLIMEKCECSLKQELQKI

--SKKVFSLRETLKFISTSFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGAS
   .| |     .. |   .  || .| . | | |||| |||.   .|| ..||| |
QKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGIS

Kinase 18320.AA Ciliate-C6 382-436 42 1.4e-09 30.1 In-house 129-185 (306) Show / Hide
Range on Protein: 382-436
Range on HMM: 129-185/306
Sequence Identity: 42% (24 aa)

KKVFSLRETLKFISTSFHLLIVLRQ-KYIYHSDIKPGNILKIDD-NNYQLSDFGASQ
.. |.  | ..| .    .|  ..    | | |||| ||| .|| ||| |||||..|
YEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQ

Kinase 18320.AA Ciliate-E3 401-435 48 7.2e-08 20.93 In-house 116-153 (202) Show / Hide
Range on Protein: 401-435
Range on HMM: 116-153/202
Sequence Identity: 48% (19 aa)

LIVLRQKYIYHSDIKPGNILKIDDNN----YQLSDFGAS
.| . .| | |||||| ||| .| ||     . .|||.|
MIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGES

Kinase 18320.AA S_TKc 291-536 15 3e-07 -70.57 SMART 1-231 (231) Show / Hide
Range on Protein: 291-536
Range on HMM: 1-231/231
Sequence Identity: 15% (42 aa)

FKLGDHINSGGEADIFTNQNYD---YIVYRVIKLNGDEDLRKQEKELLRLQELQEQNIFNIDSSHLIEDKINHTKYIIYVMQKCKM---SLQDEILSKKV
......| .|. .  .  .. .   .    .||     .  ..| ..|.    .  || ..  .          ...  ||  |     .| | | ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK---HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR

------FSLRETLKFISTSFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGASQYVDFIDPFCDFEMYTPSFTP---QKKEKNLPFYH---DIYSF
      |.  .. ...   .  |  . .. | | |.|| ||| .|. .  ..||| .  .       .    || . .          .. .   |..|.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENIL-LDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL------GYGKCKCDWWSC

GKTIQKLLI-----QLENQSEISDELNKFIKEICKDDENSINLDCFKLQRKFINILME--FTNDEVIK--------AFF
| ..  .|      .         .... .| |.         ..  . ||  .   |   |  |. .         .|
GCILYEMLCGYPPFP---------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 18320.AA Ciliate-A1 409-446 36 2e-06 17.95 In-house 122-159 (301) Show / Hide
Range on Protein: 409-446
Range on HMM: 122-159/301
Sequence Identity: 36% (14 aa)

IYHSDIKPGNILKIDDNNYQLSDFGASQYVDFIDPFCD
| |.|.||.|||  .|. . . |.| |.   .    ||
ILHRDLKPQNILIHFDDKWKICDLGMSKQLEQNQDCCD

Kinase 18320.AA RAN 409-433 62 2.2e-05 13.89 In-house 170-195 (324) Show / Hide
Range on Protein: 409-433
Range on HMM: 170-195/324
Sequence Identity: 62% (17 aa)

IYHSDIKPGNILKID--DNNYQLSDFG
||| |||| ||| ||  | |  | |.|
IYHCDIKPENIL-IDGIDWNIYLCDWG

Kinase 18320.AA FRAY 411-435 56 2.7e-05 12.05 In-house 130-154 (277) Show / Hide
Range on Protein: 411-435
Range on HMM: 130-154/277
Sequence Identity: 56% (14 aa)

HSDIKPGNILKIDDNNYQLSDFGAS
| ||| ||||  .| . |..||| |
HRDIKAGNILIGEDGTIQIADFGVS

Kinase 18320.AA Ciliate-E8 409-435 44 6e-05 11.41 In-house 110-138 (138) Show / Hide
Range on Protein: 409-435
Range on HMM: 110-138/138
Sequence Identity: 44% (13 aa)

IYHSDIKPGNIL-KI-DDNNYQLSDFGAS
| |.|.|  ||| .  || .  . ||| |
IIHCDFKLNNILVQRNDDTKIKIIDFGFS

Kinase 18320.AA LKB 409-433 52 6.6e-05 10.56 In-house 125-149 (265) Show / Hide
Range on Protein: 409-433
Range on HMM: 125-149/265
Sequence Identity: 52% (13 aa)

IYHSDIKPGNILKIDDNNYQLSDFG
. | ||||||.|   ||   ..|||
VVHKDIKPGNLLLTHDNTLKICDFG

Kinase 18320.AA PHK 409-433 56 0.000318 10.03 In-house 130-154 (273) Show / Hide
Range on Protein: 409-433
Range on HMM: 130-154/273
Sequence Identity: 56% (14 aa)

IYHSDIKPGNILKIDDNNYQLSDFG
| | | || ||| .|. |  .||||
IVHRDLKPENILCDDNMNIKISDFG