Gene 18319 (Tetrahymena)
18319
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 18319.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 18319.AA | Ciliate-E1 | 915-1085 | 20 | 5.2e-18 | 55.53 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 915-1085 Range on HMM: 1-202/202 Sequence Identity: 20% (41 aa) LDSDSEKFLRQIFKLGDHINSGGEADIFTNQN-NDNIVYRELQQQN-ILNIDSSH----LIEDKV-NHTKYIIYAIQKCQMSLYDEIL------------ . . |. . .... ...|. . | ...| |.| . |..... |... . .|. . . .| ...|..||.|.. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ -SKKVFSLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGASQ-----QVNFIDPFCNFEMYTPGFKPQ------DRVKNLPFYHD .. |. . .. | ... || |.|. |.|.|||| |||. ...||...||| |. | . .. .. ..| | . . .. .. . | QNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSD IY || IY |
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| Kinase | 18319.AA | Ciliate-B2 | 983-1050 | 36 | 1.6e-17 | 37.67 | In-house | 80-151 (197) | Show / Hide |
Range on Protein: 983-1050 Range on HMM: 80-151/197 Sequence Identity: 36% (26 aa) IQKCQMSLYDEIL----SKKVFSLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGAS ..||. || .|. .| | .. | . || .| . | | |||| |||. .|| ..||| | MEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGIS |
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| Kinase | 18319.AA | Ciliate-C6 | 985-1054 | 36 | 1e-10 | 34.19 | In-house | 117-188 (306) | Show / Hide |
Range on Protein: 985-1054 Range on HMM: 117-188/306 Sequence Identity: 36% (26 aa) KCQMSLYDEILSKKVFSLRETLKFISTAFHLLIVLRQ-KYIYHSDIKPGNILKIDD-NNYQLSDFGASQQVN | ..... .. |. | ..| . .| .. | | |||| ||| .|| ||| |||||..|| . KQEINIFSFNYKYEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLF |
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| Kinase | 18319.AA | Ciliate-E3 | 1016-1052 | 48 | 5.5e-08 | 21.3 | In-house | 116-155 (202) | Show / Hide |
Range on Protein: 1016-1052 Range on HMM: 116-155/202 Sequence Identity: 48% (20 aa) LIVLRQKYIYHSDIKPGNILKIDDNN----YQLSDFGASQQ .| . .| | |||||| ||| .| || . .|||.| | MIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGESKQ |
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| Kinase | 18319.AA | S_TKc | 927-1156 | 14 | 2.1e-07 | -68.39 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 927-1156
Range on HMM: 1-231/231
Sequence Identity: 14% (39 aa)
FKLGDHINSGGEADIFTNQNND-----------NIVYRELQQQNILNIDSSHLIEDKVNHTKYIIYAIQKCQM---SLYDEILSKKV------FSLRETL
......| .|. . . .... . ..||.| . . . | . ... | .|.| | ... |. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR
KFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGASQQVNFIDPFCNFEMYTPGFKPQDRVKNLPFYH---DIYSFGKTIQKLLIQQLENQT
... . | . .. | | |.|| ||| .|. . ..||| . |. . || . . . .. . |..|.| .. .| . .
FYMYQICCALEYCHSHGIIHRDLKPENIL-LDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-
EIYDCLNKFIKEICKDDENSINVDCFELPKKFINKIMKF------TNDEVIE----VFLEEYL
... .| |. . | ||.|.... | |. . . . ...
----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | 18319.AA | Ciliate-A1 | 1024-1055 | 40 | 2.1e-07 | 21.21 | In-house | 122-153 (301) | Show / Hide |
Range on Protein: 1024-1055 Range on HMM: 122-153/301 Sequence Identity: 40% (13 aa) IYHSDIKPGNILKIDDNNYQLSDFGASQQVNF | |.|.||.||| .|. . . |.| |.| . ILHRDLKPQNILIHFDDKWKICDLGMSKQLEQ |
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| Kinase | 18319.AA | RAN | 1024-1048 | 62 | 2.2e-05 | 13.89 | In-house | 170-195 (324) | Show / Hide |
Range on Protein: 1024-1048 Range on HMM: 170-195/324 Sequence Identity: 62% (17 aa) IYHSDIKPGNILKID--DNNYQLSDFG ||| |||| ||| || | | | |.| IYHCDIKPENIL-IDGIDWNIYLCDWG |
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| Kinase | 18319.AA | FRAY | 1026-1050 | 56 | 2.7e-05 | 12.05 | In-house | 130-154 (277) | Show / Hide |
Range on Protein: 1026-1050 Range on HMM: 130-154/277 Sequence Identity: 56% (14 aa) HSDIKPGNILKIDDNNYQLSDFGAS | ||| |||| .| . |..||| | HRDIKAGNILIGEDGTIQIADFGVS |
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| Kinase | 18319.AA | C8 | 1019-1053 | 46 | 4.4e-05 | 13.73 | In-house | 139-177 (226) | Show / Hide |
Range on Protein: 1019-1053 Range on HMM: 139-177/226 Sequence Identity: 46% (18 aa) LRQKYIYHSDIKPGNILKIDDNNYQ----LSDFGASQQV . .| | | |||| |.| |.|| |.||| . || IHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQV |
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| Kinase | 18319.AA | LKB | 1024-1059 | 38 | 5.7e-05 | 10.76 | In-house | 125-160 (265) | Show / Hide |
Range on Protein: 1024-1059 Range on HMM: 125-160/265 Sequence Identity: 38% (14 aa) IYHSDIKPGNILKIDDNNYQLSDFGASQQVNFIDPF . | ||||||.| || ..||| |.. .. VVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRD |
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| Kinase | 18319.AA | Ciliate-E8 | 1024-1050 | 44 | 6e-05 | 11.41 | In-house | 110-138 (138) | Show / Hide |
Range on Protein: 1024-1050 Range on HMM: 110-138/138 Sequence Identity: 44% (13 aa) IYHSDIKPGNIL-KI-DDNNYQLSDFGAS | |.|.| ||| . || . . ||| | IIHCDFKLNNILVQRNDDTKIKIIDFGFS |
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| Kinase | 18319.AA | Ciliate-B2 | 1069-1088 | 45 | 0.064212 | 0.18 | In-house | 178-197 (197) | Show / Hide |
Range on Protein: 1069-1088 Range on HMM: 178-197/197 Sequence Identity: 45% (9 aa) FKPQDRVKNLPFYHDIYSFG .. | | |. | |||| | DHNQTFVTNIDFQSDIYSMG |
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