Gene 14987 (Tetrahymena)
14987
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 14987.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 14987.AA | Ciliate-A8 | 30-114 | 45 | 8.8e-28 | 93.23 | In-house | 1-85 (151) | Show / Hide |
Range on Protein: 30-114 Range on HMM: 1-85/151 Sequence Identity: 45% (39 aa) YEYLKMLEQGDSSLVVVAFSQKLQYQVAVKIIKTRGAINQVNLLQVDKEIQILQNLQSEMYVLKIFEKIEEYNLGLLAIVMELCD |.| | ||.|| |.||.| |...| |||.|||| .|..| .|.||..|... | |.|.| |.|. ..|. |||.|.|| YKYQKVLEKGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCD |
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Kinase | 14987.AA | Ciliate-E1 | 36-127 | 26 | 1.9e-19 | 60.24 | In-house | 1-99 (202) | Show / Hide |
Range on Protein: 36-127 Range on HMM: 1-99/202 Sequence Identity: 26% (26 aa) LEQGDSSLVVVAFSQKLQ-YQVAVKIIKTRGAINQVNLLQVDKEIQ-ILQNLQSEMYVLKIFEKIE-EYNLGLLAIVMELCDYLFYINQ-----IIIQKL ...|..|.|. |..|. . .|||.|||......||...... ||.. |.. ...|.|...|.. |. ..|.. ..|....|. |. .| ...|.. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC |
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Kinase | 14987.AA | CAMK | 35-114 | 14 | 2.5e-08 | 22.19 | In-house | 1-143 (425) | Show / Hide |
Range on Protein: 35-114 Range on HMM: 1-143/425 Sequence Identity: 14% (21 aa) MLEQGDSSLVVVAFSQKLQ------------YQVAVKIIKTRGAIN-------------------------QVNLLQVDKEIQILQNLQ------SEMYV | .| . | .. . . .||.|||... . . .... .| .||.|...|| . . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LKIFEKIEE-------YNLG-----------LLAIVM---ELCD .|..| .| . . .|| |.|. IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCS |
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Kinase | 14987.AA | S_TKc | 30-223 | 15 | 6e-08 | -60.4 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 30-223 Range on HMM: 1-231/231 Sequence Identity: 15% (41 aa) YEYLKMLEQGDSSLVVVAFSQKLQYQVAVKIIKTRGAINQVNLLQVDKEIQILQNLQSEMYVLKIFEKIEEYNLGLLAIVMELCDY-----LFYINQIII || |. . .| . | . | . .||.|||| .. .|||||.. .. |... ... . | .|||.|| . || . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR ------QKLPSISDISSEMT-----------------------NEQRLK---------------------------SL-YSDVFSIGLILTEAFISRQLS . . .. .| ..| . .|. |.| || | . . . HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPF PEELKNLKSQIIFNVFPFLNNYENIRFFDKILLKMIDQNQDLRLLPKDLLY------NLKAF | ... . .| . | .. |. . . . |. ..| . | P-QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 14987.AA | CAMKL | 30-114 | 24 | 1.1e-07 | 20.39 | In-house | 1-104 (297) | Show / Hide |
Range on Protein: 30-114 Range on HMM: 1-104/297 Sequence Identity: 24% (26 aa) YEYLKMLEQGDSSLVVVAFSQKL-QYQVAVKIIKTRGAINQVNLLQ------------VDKEIQILQNLQ--SEMYVLKIFEKIE--EY---NLGLLAIV |. .| | .| . | | ... . .||.|||. ... | . .. . .||||.. |. . |..| || |. . . . .| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV MELCD ||.|. MEYCS |
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Kinase | 14987.AA | Ciliate-E5 | 34-126 | 26 | 4.9e-07 | 18.72 | In-house | 5-97 (271) | Show / Hide |
Range on Protein: 34-126 Range on HMM: 5-97/271 Sequence Identity: 26% (26 aa) KMLEQGDSSLVVVAFSQKLQYQVAVKIIKTRGAINQVNLLQVDKEIQILQNLQSEMYVLKIFEKIEEY--NLGLLAIVMELCDY--LFYINQIIIQK ..| .| | .|. ..| ... .| ||.| .|| .. . .| .||....| ...| .. .... |. .. |.||.| . |.|.|| |. QILGKGGSGMVMKGCSEWNDKPIAIKIMK---CKNQKQCEDNQREFNILKQFNSP-HIIKVYQIYQYQYENMNYQFIIMERCKCDLHTYLNKIIYQM |
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Kinase | 14987.AA | Ciliate-C7 | 33-99 | 32 | 2e-06 | 17.35 | In-house | 1-70 (164) | Show / Hide |
Range on Protein: 33-99 Range on HMM: 1-70/164 Sequence Identity: 32% (23 aa) LKMLEQGDSSLVVVAFSQKLQYQVAVKIIKTR---GAINQVNLLQVDKEIQILQNLQSEMYVLKIFEKIE .. | || .||..| || . |.| .. | | |.| . || .||.||.. . ||.......| FRFLGQGQQGLVLLAKDQKTNMRYAIKGVQVRDKQGNIDQDINNQVQQEINILKQCKDSPYVVCLLHQFE |
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Kinase | 14987.AA | CMGC | 30-115 | 15 | 8e-06 | 14.1 | In-house | 1-139 (513) | Show / Hide |
Range on Protein: 30-115 Range on HMM: 1-139/513 Sequence Identity: 15% (22 aa) YEYLKMLEQGDSSLVVVAFSQKLQYQ--------------VAVKIIK----TRGAI----NQVNLLQVDKEIQILQNLQ----------------SEMYV || .| . .| . |. .. .. . . ||.|.|| ...| . ||.||..|. . .. YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI LKIFEKIEEYN---------------LGLLAIVMELCDY .|... . | . | .|.|..|. VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH |
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Kinase | 14987.AA | Ciliate-E3 | 30-113 | 24 | 5.5e-05 | 11.83 | In-house | 1-86 (202) | Show / Hide |
Range on Protein: 30-113 Range on HMM: 1-86/202 Sequence Identity: 24% (21 aa) YEYLKMLEQGDSSLVVVAFSQKLQYQVAVKIIKTRGAIN---QVNLLQVDKEIQILQNLQSEMYVLKIFEKIEEYNLGLLAIVMELC | .. | .| ..| ||.. . .|| | | .. | .. . .|.| | . |. .|.|. . . .. .. ||.|.| YTVQQILGCGQFGRVYKAFDFQNNQDVAIKAIICQNQQNEGVGEQFQKTQQEFQNCQQINSQ-NVVKCHDQYYDQQNKMIFIVQEYC |
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Kinase | 14987.AA | JNK | 30-59 | 40 | 0.000116 | 13.37 | In-house | 1-30 (309) | Show / Hide |
Range on Protein: 30-59 Range on HMM: 1-30/309 Sequence Identity: 40% (12 aa) YEYLKMLEQGDSSLVVVAFSQKLQYQVAVK | ||.. ||. .|. || | .. .||.| YQNLKFIGQGAQGIVCMAFDQVTNQRVAIK |
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Kinase | 14987.AA | STE | 30-88 | 13 | 0.000388 | 10.65 | In-house | 1-90 (359) | Show / Hide |
Range on Protein: 30-88 Range on HMM: 1-90/359 Sequence Identity: 13% (12 aa) YEYLKMLEQGDSSLVVVA---------FSQKL------QYQVAVKIIKTRGA--------------INQVNLLQVDKEIQILQNLQ--SE .| .... .| . |. | .... . .|.|... . .|. .. |. |||.|..... .. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHP |