Gene 13481 (Tetrahymena)
13481
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 13481.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 13481.AA | Ciliate-A8 | 33-117 | 46 | 1.4e-28 | 96.03 | In-house | 1-85 (151) | Show / Hide |
Range on Protein: 33-117 Range on HMM: 1-85/151 Sequence Identity: 46% (40 aa) YVYEKQISRSSSSLVVQAKSLNHNNSNVAIKILNY-KYNSKINSQKLSKQVDFLDNLKGEKYVLQFIERIQDLNQGITAIVTEYCE |.|.| . |.||||.|.||.. .|||||..| . ||| ... |.. . ..|.|||.||.|| |||..|| .|||||.|. YKYQKVLEKGDFSYVVQAYSINHQC-QVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCD |
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| Kinase | 13481.AA | Ciliate-E1 | 39-120 | 31 | 1.5e-22 | 70.45 | In-house | 1-84 (202) | Show / Hide |
Range on Protein: 39-120 Range on HMM: 1-84/202 Sequence Identity: 31% (27 aa) ISRSSSSLVVQAKSLNHNNSNVAIKILNYKYN-SKINSQKLSKQVD-FLDNLKGEKYVLQFIERIQ-DLNQGITAIVTEYCERLL |...|.|.|..||. |.|...||.|| |...| .... |...|. . ... .|.|.|..|.|. |. |.|.....|....|..|. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLK |
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| Kinase | 13481.AA | Ciliate-E2-Unclassified | 132-198 | 21 | 8.1e-10 | 30.25 | In-house | 170-262 (352) | Show / Hide |
Range on Protein: 132-198 Range on HMM: 170-262/352 Sequence Identity: 21% (20 aa) IEPEKILYSAQNN--QFLLSYLSFSR-----------------LIQFEGNEKQQGNLNYQ----SPEVINKKKPYK---ITADIFSIGVILLE | || ||.. ... . .. ...|. .... . |..||. .|||. ...... . .||.| |||| | IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYE |
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| Kinase | 13481.AA | S_TKc | 33-234 | 14 | 1.6e-08 | -51.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 33-234 Range on HMM: 1-231/231 Sequence Identity: 14% (37 aa) YVYEKQISRSSSSLVVQAKSLNHNNSNVAIKILNYKYNSKINSQKLSKQVDFLDNLKGEKYVLQFIERIQDLNQGITAIVTEYCER-----LLLIQEKQK | ..| . . . | ... . . |||||.. ... . .. | . . ... .... .|| . .|.|||. . .|..... YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR VLR---YIEPEKILYSAQ--------------------------NNQFLLSYLSFSRLIQFEGNEKQQGNLNYQSPEVINKKKPYKI-TADIFSIGVILL . . | . | .| . . .. ..|.. . | ..| .|||. .| .|. |.|.|| HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY EALL-----QRKLKGMEYLKLKSQSLISVLPDLLNEQ----------N-------HQFI | | . .. | . . |..... . .|. . |... EMLCGYPPFP-QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF |
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| Kinase | 13481.AA | C8 | 122-196 | 25 | 1.9e-08 | 25.58 | In-house | 139-226 (226) | Show / Hide |
Range on Protein: 122-196 Range on HMM: 139-226/226 Sequence Identity: 25% (22 aa) IQEKQKVLRYIEPEKILYSAQNNQF---LLSYLSFSRLIQFEGN--EKQQ----GNLNYQSPEVINK----KKPYKITADIFSIGVIL |. |. . | | |. .| ...|. |. . |. .. . . . .. |.. | ||...| | |.| |.||.|..| IHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL |
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| Kinase | 13481.AA | Ciliate-E2 | 157-196 | 35 | 4e-07 | 20.5 | In-house | 239-286 (365) | Show / Hide |
Range on Protein: 157-196 Range on HMM: 239-286/365 Sequence Identity: 35% (17 aa) IQFEGNEKQQGNLNYQSPEVINKKKP--------YKITADIFSIGVIL ||.. . |...|..||..|.|| | .||.|.|||| IQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL |
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| Kinase | 13481.AA | CAMK1 | 171-196 | 50 | 8.7e-07 | 15.69 | In-house | 179-206 (276) | Show / Hide |
Range on Protein: 171-196 Range on HMM: 179-206/276 Sequence Identity: 50% (14 aa) YQSPEVINKK--KPYKITADIFSIGVIL |. |||.. | ||| . |..|||||. YVAPEVLECKKDKPYDKACDMWSIGVIT |
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| Kinase | 13481.AA | Ciliate-E1 | 132-190 | 20 | 2e-06 | 17.38 | In-house | 135-202 (202) | Show / Hide |
Range on Protein: 132-190 Range on HMM: 135-202/202 Sequence Identity: 20% (14 aa) IEPEKILYSAQNNQFLLSYLSFSRLIQFEGNEKQ---QGNLNYQSPEVIN-------KKKPYKITADIF | |..||.. | ...... .. |.... . |. . . .|..||..| |...... ||. IKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY |
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| Kinase | 13481.AA | TKL | 153-198 | 17 | 2e-06 | 18.94 | In-house | 200-281 (364) | Show / Hide |
Range on Protein: 153-198 Range on HMM: 200-281/364 Sequence Identity: 17% (14 aa) FSRLIQFEG---------------------NEKQQGNLNYQSPEVINKK---------------KPYKITADIFSIGVILLE .|| .. .| . .| |.... .|||.... ..| .|..| |..| | LSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWE |
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| Kinase | 13481.AA | ULK | 153-196 | 22 | 2e-06 | 18.68 | In-house | 184-242 (324) | Show / Hide |
Range on Protein: 153-196 Range on HMM: 184-242/324 Sequence Identity: 22% (13 aa) FSRLIQFEGNEKQQ-----------GNLNYQSPEVIN----KKKPYKITADIFSIGVIL |.. .. .. |.|. | | .|.... .|..| . .||.|.|.|. FAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF |
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| Kinase | 13481.AA | MLK | 164-196 | 31 | 2e-06 | 18.31 | In-house | 192-226 (291) | Show / Hide |
Range on Protein: 164-196 Range on HMM: 192-226/291 Sequence Identity: 31% (11 aa) KQQGNLNYQSPEVI--NKKKPYKITADIFSIGVIL ...|.. . .|||| . .| . .|..|.||.| SNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVL |
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| Kinase | 13481.AA | HH498 | 164-198 | 40 | 2e-06 | 15.85 | In-house | 184-218 (284) | Show / Hide |
Range on Protein: 164-198 Range on HMM: 184-218/284 Sequence Identity: 40% (14 aa) KQQGNLNYQSPEVINKKKPYKITADIFSIGVILLE || ||| . .||| | | .|.|| . .. | KQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWE |
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| Kinase | 13481.AA | Ciliate-A8 | 119-147 | 48 | 1.3e-05 | 16.21 | In-house | 123-151 (151) | Show / Hide |
Range on Protein: 119-147 Range on HMM: 123-151/151 Sequence Identity: 48% (14 aa) LLLIQEKQKVLRYIEPEKILYSAQNNQFL ||. ||| .. | |. |||| ..|||. LLVFQEKGIIHCDIKPQNILYSWSKNQFI |
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| Kinase | 13481.AA | Pkinase | 169-203 | 40 | 0.000948 | 14.34 | Pfam | 175-209 (293) | Show / Hide |
Range on Protein: 169-203 Range on HMM: 175-209/293 Sequence Identity: 40% (14 aa) LNYQSPEVINKKKPYKITADIFSIGVILLEALLQR ..| .||||.. ..| .|..|.|.|| | |. | PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR |
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| Kinase | 13481.AA | TKL | 39-118 | 11 | 0.04078 | 3.43 | In-house | 1-122 (364) | Show / Hide |
Range on Protein: 39-118
Range on HMM: 1-122/364
Sequence Identity: 11% (14 aa)
ISRSSSSLVVQAKSLNHN-------NSNVAIKILNYKYNSKINS---------------------QKLSKQVDFLDNLKGE---KYVLQFIERIQDLNQG
| . ... | ..| ... . ||.|... ..... .. ... .. . ... ..||. .. ..|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
I-----------TAIVTEYCER
.||.|||..
CVCMHPVGPWGQLCIVMEYCPG
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| Kinase | 13481.AA | C8 | 37-74 | 18 | 0.296088 | 0.25 | In-house | 5-41 (226) | Show / Hide |
Range on Protein: 37-74 Range on HMM: 5-41/226 Sequence Identity: 18% (7 aa) KQISRSSSSLVVQAKSLNHNNSNVAIKILNYKYNSKIN . .| . ..|..|| .. .| ....|.. .. ...|. QYLSFGAYGMVLKAKNVK-DNREIVLKFQKCQNKQDIQ |
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