Gene 12560 (Tetrahymena)

12560

Species: Tetrahymena
Alias: 19.m00352, 12560, 841, TTHERM_00227500, PreTt12560
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
12560.AA Protein None 912 None Fasta, JSON
12560.kin_dom Protein Kinase Domain None 61 None Fasta, JSON
12560.NA RNA None 2739 None Fasta, JSON

Protein domain

Protein domains of 12560.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 12560.AA Ciliate-B2 353-435 40 5e-37 84.55 In-house 1-85 (197) Show / Hide 
Range on Protein: 353-435
Range on HMM: 1-85/197
Sequence Identity: 40% (34 aa)

YYLGKYIAEGGFGVVFDGK-IYQNNKIQEVIFKIQFT-DKQNINESEEEYNIMKGFEENINLIRAIDYKKIDKNVSVILMEKCEY
|||.|||..||.|....|     . . |...|||.|  .  . .| ..|..||| || ||| .. ||. .|.... |. |||||.
YYLCKYINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMFEYNINVVKYIDHIQINETIDVLIMEKCEC
Kinase 12560.AA Ciliate-B2 436-496 36 1.1e-29 66.9 In-house 130-197 (197) Show / Hide 
Range on Protein: 436-496
Range on HMM: 130-197/197
Sequence Identity: 36% (25 aa)

IKPSNILINRYGIHVFSDFGTSTKNKNDQPIQVKGYTKSFAPKEVINKG-------DVNYESDVFSLG
|||.|||. ..|  |..||| |   |..| |..|| ||..|..| ...         ... ||..|.|
IKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 12560.AA Ciliate-E1 436-493 42 7.5e-22 68.18 In-house 135-202 (202) Show / Hide 
Range on Protein: 436-493
Range on HMM: 135-202/202
Sequence Identity: 42% (29 aa)

IKPSNILINRYGIHVFSDFGTST--KNKNDQPIQVKGYTKSFAPKEVIN------KGD--VNYESDVF
|||.|||||..|..|..|||.|   ||...| .|.||||....|.|..|      . .  .||.||..
IKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 12560.AA Ciliate-E1 359-435 32 7.6e-18 54.99 In-house 1-81 (202) Show / Hide 
Range on Protein: 359-435
Range on HMM: 1-81/202
Sequence Identity: 32% (27 aa)

IAEGGFGVVFDGKIYQNN--KIQEVIFKIQFT-DKQNINESEEEYN-IMKGFEENINLIRAIDYKKIDKN-VSVILMEKCEY
|..|.|..||..|...||  .....|....|  .......  .||. ||| |......|  |||.|||.| ...|..|.|..
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCC
Kinase 12560.AA Ciliate-E3 436-503 27 8.5e-10 27.03 In-house 129-202 (202) Show / Hide 
Range on Protein: 436-503
Range on HMM: 129-202/202
Sequence Identity: 27% (20 aa)

IKPSNILINRYG---IHVFSDFGTSTKNKNDQ-PIQVK--GYTKSFAPKEVINKGDVNYESDVFSLGKTLQFVF
|||.|||.       |  ..||| | . ...   .. .  | |  .|..|.  .. .  |||  |.|  .  . 
IKPDNILVDKNNNQLIIKICDFGESKQLRKNKGHTHTQYQGWTPFYAAPEQNDQQQISKESDYYSVGAVFCQLC
Kinase 12560.AA Ciliate-E2 436-496 19 2.6e-08 24.61 In-house 187-283 (365) Show / Hide 
Range on Protein: 436-496
Range on HMM: 187-283/365
Sequence Identity: 19% (20 aa)

IKPSNILINRYGIHVFSDFGTSTKNKND----------QPIQVKG-----------------------YTKSFAPKEVINKGDVN---------YESDVF
|||.|||.        .|||.|.|...|          . ..  .                       .|  . . |..|... .         |..|..
IKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

SLG
|||
SLG
Kinase 12560.AA S_TKc 353-550 15 2.3e-07 -68.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 353-550
Range on HMM: 1-231/231
Sequence Identity: 15% (40 aa)

YYLGKYIAEGGFGVVFDGKIYQNNKIQEVIFKIQFTDKQNINESEEEYNIMKGFEENINLIRAIDYKKIDKNVSVILMEKCEY-----------------
| ... | .|.||.|.  | . ..  ..|  ||        .  . | .|.|      |... .|.     .   . || |.                  
YEILRKIGKGAFGKVY--KCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-------------------------------IKPSNILINRYGIHVFSDFGTSTKNKNDQPIQVKGYTKSFAPKEVINKGDVNY-ESDVFSLGKTL----
                               .||.|||...      .||| ...            |  . . ||.     .. ..|. |.| .|    
RFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

--QFVFKEYEKLKIFNQNEKAMLEKFKQILKDYALREQVSERKTCLELHK--------AFY
  .  |   .  ..|..      . .|. . .  |.   ..| |. |. .         . 
CGYPPFP--QMQMMFKKIG---SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 12560.AA C8 436-499 25 1.2e-05 15.67 In-house 149-226 (226) Show / Hide 
Range on Protein: 436-499
Range on HMM: 149-226/226
Sequence Identity: 25% (20 aa)

IKPSNILINRYGIHV----FSDFGTSTKNKNDQP-IQVKGY----TKSFAPKEVINK-----GDVNYESDVFSLGKTL
|||.|.|.   .  .     .||| ... . ..  || | .    |. .   |...|      . . .||.||.|  |
IKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 12560.AA Ciliate-C5 354-404 37 0.000187 10.3 In-house 2-48 (260) Show / Hide 
Range on Protein: 354-404
Range on HMM: 2-48/260
Sequence Identity: 37% (19 aa)

YLGKYIAEGGFGVVFDGKIYQNNKIQEVIFKIQFTDKQNINESEEEYNIMK
||  ||..|||| ||. |  .|. |  |  |   .. . |.| |.  ...|
YLTSYISQGGFGCVFEAK--YNEEI--VAVKCSKPNFEKIKEEEKIMKLLK
Kinase 12560.AA Axl 353-407 32 0.000193 11.39 In-house 1-59 (267) Show / Hide 
Range on Protein: 353-407
Range on HMM: 1-59/267
Sequence Identity: 32% (19 aa)

YYLGKYIAEGGFGVVFDGKIYQNN----KIQEVIFKIQFTDKQNINESEEEYNIMKGFE
  ||| . || || | .|.. |.     |.   ..||.   ...| |   |   || |.
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFD
Kinase 12560.AA AGC 435-475 16 0.000247 5.53 In-house 180-265 (395) Show / Hide 
Range on Protein: 435-475
Range on HMM: 180-265/395
Sequence Identity: 16% (14 aa)

YIKPSNILINRYGIHVFSDFGTSTKNKNDQPIQVKGY---------------------------------------------TKSF
|.|| |||... |    .||| .....||. ......                                             |..|
YLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTF
Kinase 12560.AA Ciliate-A9 353-377 29 0.000332 4.94 In-house 1-27 (392) Show / Hide 
Range on Protein: 353-377
Range on HMM: 1-27/392
Sequence Identity: 29% (8 aa)

YYLGKYIAEGGFGVVFDGKIYQ--NNK
. ..| | || ||.|. ..  |  ...
FEPIKIIGEGAFGCVIQCRDIQQEDKQ
Kinase 12560.AA Ciliate-E2-Unclassified 436-496 25 0.001256 8.48 In-house 170-257 (352) Show / Hide 
Range on Protein: 436-496
Range on HMM: 170-257/352
Sequence Identity: 25% (22 aa)

IKPSNILINRYG---IHVFSDFGTSTKNKND------------QPIQVKGYTKSFAPK--------EVINKGDVN----YESDVFSLG
|||.|||..  |       .||| | |....            ...| . .|..  |         ||. .   .    |..|..|||
IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG
Kinase 12560.AA Ciliate-E2 353-435 18 0.001535 8.0 In-house 1-118 (365) Show / Hide 
Range on Protein: 353-435
Range on HMM: 1-118/365
Sequence Identity: 18% (22 aa)

YYLGKYIAEGGFGVVFDGKIYQNNK------IQEVI---------FKIQFTDKQNI-----NESEEEYNIMKGFEE---------------NINLIRAID
| . | | .|.||.|. .| ....|      |.  .         .||..  . ..     .. . | .||.  ..               . |.|. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

YKK-IDKNVSVILMEKCEY
. . .|.|   . || |..
CFQEKDDNNIYLVMEYCQG
Kinase 12560.AA Ciliate-E2-Unclassified 353-435 22 0.008949 5.48 In-house 1-105 (352) Show / Hide 
Range on Protein: 353-435
Range on HMM: 1-105/352
Sequence Identity: 22% (24 aa)

YYLGKYIAEGGFGVVFDGKIYQNN---------KIQEVIFKIQ-FTDKQNINESEEEYNIMKGFEEN---------------INLIRAIDYKKIDKNVSV
| ..| | .||||.|.  .  ...         |||..  |.. . | . .|| .|. |..| .  .               ..... ..... ..|.  
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNI-Y

ILMEKCEY
| ||.||.
IVMEYCEG
Kinase 12560.AA Ciliate-E3 353-392 25 0.065082 2.1 In-house 1-38 (202) Show / Hide 
Range on Protein: 353-392
Range on HMM: 1-38/202
Sequence Identity: 25% (10 aa)

YYLGKYIAEGGFGVVFDGKIYQNNKIQEVIFKIQFTDKQN
|   . .. |.||.|.  | .  .  |.|  | .....|.
YTVQQILGCGQFGRVY--KAFDFQNNQDVAIKAIICQNQQ
Kinase 12560.AA C8 357-408 28 0.119211 1.64 In-house 5-52 (226) Show / Hide 
Range on Protein: 357-408
Range on HMM: 5-52/226
Sequence Identity: 28% (15 aa)

KYIAEGGFGVVFDGKIYQNNKIQEVIFKIQFTDKQNINESEEEYNIMKGFEE
.|.  |..|.|  .|  ..|.  |.. |.|    || .. ...  ||| .|.
QYLSFGAYGMVLKAKNVKDNR--EIVLKFQKC--QNKQDIQNIESIMKEYEM