Gene 9066 (Tetrahymena)

9066

Species: Tetrahymena
Alias: PreTt09066, 152.m00086, 891, TTHERM_00858020, 9066
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
9066.AA Protein None 1917 None Fasta, JSON
9066.kin_dom Protein Kinase Domain None 1147 None Fasta, JSON
9066.NA RNA None 5754 None Fasta, JSON

Protein domain

Protein domains of 9066.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 9066.AA Ciliate-E2 1587-1826 20 9.9e-16 50.46 In-house 1-289 (365) Show / Hide 
Range on Protein: 1587-1826
Range on HMM: 1-289/365
Sequence Identity: 20% (68 aa)

FNVFNICYISQGSEGKVYKA-----------KMIDRSY----------KQFKCAIKIIQIAKQQEIFQKEIDIRNDINLIEEEYNRLQPNQRNEKINPYG
... ..  | ||. |.|||.           |.||  .          |... |.||. . .| |.. .||.| . ||  .                 | 
YKFIKK--IGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIM-KKNQIEQIKQEIHIMREINC-F-----------------YK

---------------IVKYYYDFKT-KEGYQGVVMEYCNE-TLESLMKNENIQNHELIKETFINKTNSYRDLCFMQLILQTLK---------------AL
               |.|.|. |.. .. .   |||||.  .|....|| ... .. |.   . . ... .    ... | |.               ||
KINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE---K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILAL

NFLHYEDYIGGIKKVSYIHRDIKPMNIMIQIDTVNEFSVKIIDLGGISKQSKHDQDD----------------------------------FDGTIAFYP
..|| .  |        ||||||| ||..         .||||.| .||. . |...                                  . ||  . .
EYLHSKNNI--------IHRDIKPENILF---------IKIIDFG-LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMA

PEYIQQQVTT-------FDKSSDVWAIGICIYRL
|| .. .  .        |...|.|..|...|..
PEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM
Kinase 9066.AA S_TKc 1589-1889 19 7.5e-15 40.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 1589-1889
Range on HMM: 1-231/231
Sequence Identity: 19% (59 aa)

VFNICYISQGSEGKVYKAKMIDRSYKQFKCAIKIIQIAKQQEIFQKEIDIRNDINLIEEEYNRLQPNQRNEKINPYGIVKYYYDFKTKEGYQGVVMEYCN
   .  | .|. |||||.. ..    . ..|||||            ..||. |.. ..              .   |||.|. | .  ..  .|||||.
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-----------EHIRREIQILKK--------------HHPNIVKLYDVFQD--DHLYMVMEYCD

E---TLESLMKNENIQ-NHELIKETFINKTNSYRDLCFMQLILQTLKALNFLHYEDYIGGIKKVSYIHRDIKPMNIMIQIDTVNEFSVKIIDLGGISKQS
    .| ...|. . . ..  . |  .             .. |...||...|             ||||.|| ||..         .||.|  |...| 
GDLGDLFDYIKKRGRHGLRFPFPE-HA-----------RFYMYQICCALEYCHSHG---------IIHRDLKPENILLDE------HIKICDF-GLARQL

KHDQDDFDGTIAFYPPEYIQQQVTTFDK-SSDVWAIGICIYRLFAISQIWNRLDAITLRQQEGNERDQIVYEYGSEILKILLTQDYQQRNQKNYLEK--V
    . | ||  . .|| .      ..| ..|.|..|...| ...    .   .. ....           . . .... .|. | ..|     . .  .
----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

IEKAAQCV
  |. . .
DIKCHPWF
Kinase 9066.AA TKL 1722-1824 18 3.9e-14 47.32 In-house 134-280 (364) Show / Hide 
Range on Protein: 1722-1824
Range on HMM: 134-280/364
Sequence Identity: 18% (28 aa)

FMQLILQTLKALNFLHYEDY-IGGIKKVSYIHRDIKPMNIMIQIDTV----------NEFSVKIIDLG--GISKQSKHDQDD------------------
.....|.. ...|.|| ..   ..  |   ||||.|. ||..  .            ..  .|| |.|     .||....|                   
RCRWALDIARGMNYLHSMNPKWCT--KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTM

-FDGTIAFYPPEYIQQQVT--------------TFDKSSDVWAIGICIY
   ||... .|| ...|                ......||.. ||...
TQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLW
Kinase 9066.AA C8 1745-1823 29 2.3e-13 42.85 In-house 139-226 (226) Show / Hide 
Range on Protein: 1745-1823
Range on HMM: 139-226/226
Sequence Identity: 29% (26 aa)

IKKVSYIHRDIKPMNIMIQIDTVNEFSVKIIDLG---GISKQSKHDQDDFD---GTIAFYPPEYIQQ---QVTTFDKSSDVWAIGICI
|.    .||||||.|.... |  . |..|. |.|    .||  .|.|. .    || |.  || ...   |.  . . ||.. .|.  
IHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 9066.AA Ciliate-E2-Unclassified 1595-1826 20 2.8e-13 42.45 In-house 7-263 (352) Show / Hide 
Range on Protein: 1595-1826
Range on HMM: 7-263/352
Sequence Identity: 20% (58 aa)

ISQGSEGKVYKAKMIDRSYKQFKCAIKIIQIAKQQEIFQKEIDIRNDINLIEEEYNRLQPNQRNE----------KINPYGIVKYYYDFKTKEGYQGVVM
| ||. |||||.. ..  ....     . .. |.|.. || |   ..|.....| |...    ..          . .|  .. .... .... .   ||
IGQGGFGKVYKCQHKKQKQYYA-----MKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCNE-TLESLMKN------------ENIQNHELIKETFIN---KTNSYRDLCFMQLILQTLKALNFLHYEDYIGGIKKVSYIHRDIKPMNIMIQIDTVN
|||.  .|.  .|.            .|... . . |  .    .          ... | |..|..||..  |        ||||||| ||... .   
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKA---------KFYFAQILQGLEYLHHKNNI--------IHRDIKPENILFDNNGK-

EFSVKIIDLGGISKQSKHDQDDFD------------------GTIAFY----PPEYIQQQVTTFD--KSSDVWAIGICIYRL
 . .||||.| ..|. . ...| .                  ||. .     .||..|.|       ...|.|. |...| .
NYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM
Kinase 9066.AA Ciliate-C8 1723-1823 21 3.9e-12 40.09 In-house 122-238 (238) Show / Hide 
Range on Protein: 1723-1823
Range on HMM: 122-238/238
Sequence Identity: 21% (27 aa)

MQLILQTLKALNFLHYEDYIGGIKKVSYIHRDIKPMNIMIQIDTVNEFSVKIID------LGGISKQSKHDQ---------DDFD------GTIAFYPPE
...  | .  .|.||. .          .||||||.|.  . |. . ...|. |      .|  |. .|             |        |.... .||
EIIAIQMIDSVNYLHCFN---------IMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPE

YIQQ----QVTTFDKSSDVWAIGICI
 ...    |   | | ||..  |.. 
VEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 9066.AA Pkinase 1726-1824 29 6.2e-12 43.29 Pfam 114-203 (293) Show / Hide 
Range on Protein: 1726-1824
Range on HMM: 114-203/293
Sequence Identity: 29% (30 aa)

ILQTLKALNFLHYEDYIGGIKKVSYIHRDIKPMNIMIQIDTVNEFSVKIIDLGGISKQ---SKHDQDDFDGTIAFYPPEYIQQQVTTFDKSSDVWAIGIC
..|.|..|...| .         . ||||.|| ||.|  . ... .|||.|  |..||   ...  ..| ||. . .|| |.   .  ....|.|..|. 
MYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDF-GLAKQFDYNNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWSCGCI

IY
.|
LY
Kinase 9066.AA STE 1726-1823 26 2.8e-10 32.64 In-house 157-258 (359) Show / Hide 
Range on Protein: 1726-1823
Range on HMM: 157-258/359
Sequence Identity: 26% (32 aa)

ILQTLKA-LNFLHYEDYIGGIKKVSYIHRDIKPMNIMIQIDTVNEFSVKIIDLGGISKQSKH------------------DQDDFDGTIAFYPPEYIQQQ
. |.||. |..||            .||||||| ||..         ||..| |  .. ...                    . | ||  .  || |||.
CRQILKGLLYYLHSHH---------IIHRDIKPANILL---------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQN

VTT----FDKSSDVWAIGICI
 ..     | ..|.| .|..|
GQGRDKGYDTKCDIWSLGCTI
Kinase 9066.AA CAMK 1751-1821 17 8e-10 27.09 In-house 201-322 (425) Show / Hide 
Range on Protein: 1751-1821
Range on HMM: 201-322/425
Sequence Identity: 17% (21 aa)

IHRDIKPMNIMIQIDTVNE-------------FSVKIIDLGGISKQSKHD-------------------------QDDFDGTIAFYP-PEYIQQQ-----
.|||.|| ||... .  ..             . .|||| |   |  . .                           .| || .. . || ....     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------VTTFDKSSDVWAIGI
        .  ....|.|..|.
QNATDEEKPYYGPKCDMWSCGV
Kinase 9066.AA MLK 1731-1824 26 1.4e-09 29.58 In-house 135-227 (291) Show / Hide 
Range on Protein: 1731-1824
Range on HMM: 135-227/291
Sequence Identity: 26% (27 aa)

KALNFLHYEDYIGGIKKVSYIHRDIKPMNIMIQ---IDTVNEFSVKIIDLGGISK-QSKHDQD---DFDGTIAFYPPEYIQQ-QVTTFDKSSDVWAIGIC
.....||...      .. .||||.|. ||.|        ..  .|| | .|.|.  .... .   .. || |.  || ||| . .......||| .|..
RGMHYLHSMA------PKPIIHRDLKSHNILIDEICH-DMHHGTLKICD-FGTSRDWHQMC-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVV

IY
..
LW
Kinase 9066.AA AGC 1750-1824 18 2.9e-09 18.59 In-house 175-296 (395) Show / Hide 
Range on Protein: 1750-1824
Range on HMM: 175-296/395
Sequence Identity: 18% (24 aa)

YIHRD-IKPMNIMIQIDTVNEFSVKIIDLGGISKQSKHDQ-----------------------------------------------------DDFDG--
.|||| .|| ||..  |      .|. | |  .|. . |.                                                       | |  
IIHRDYLKPENILLDED----GHIKLTDFG-LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPC

TIAFYPPEYIQQQVTTFDKSSDVWA--IGICIY
|  . .|| .       .|. | |.   |...|
TPEYMAPEIL------YGKACDWWSFGLGCLMY
Kinase 9066.AA TyrKc 1589-1882 15 2.6e-07 -104.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 1589-1882
Range on HMM: 1-280/280
Sequence Identity: 15% (52 aa)

VFNICYISQGSEGKVYKAKMIDRSYKQFKCAIKIIQIAKQQEIFQKEIDIRNDINLIEEE--YNRLQPNQRNEKINPYGIVKYYYDFKTKE------GYQ
.  .  .  |  |.|||....       ..|.| ..  .       . |... ...  .    .               ||. |    ...      .  
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHP-------------NIVRLYGVCTQQGRNFMYIEPL

GVVMEYCNE--TLESLMKNENIQNHELIKETFINKTNSYRDLCFMQLILQTLKALNFLHYEDYIGGIKKVSYIHRDIKPMNIMIQIDTVNEFSVKIIDLG
 .||||.     .. | |...                      . .  .|  .  ..||            .||||.   |...  .      ||| |  
MIVMEYMPHGDLKDYLRKHRPK----------------LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENH----TVKISDF-

GISKQSKHD-------QDDF-----DGT----IAFYPPEYIQQQVTTFDKSSDVWAIGICI----------YRL-----FAISQIWNRLDAITLRQQEGN
| |.  ..|       .        .|     |  ..|| |  .  .|   ||||. |.|.          |          ... .....   . |  |
GLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPN

-------ERDQIVYEYGSEILKILLTQDYQQRNQKNYLEKVI
       .  . .|    .| |     |  .|   . . . .
DYPMSFVCCPDEMY----QIMKQCWHEDPEDRPTFSEIHECF
Kinase 9066.AA ULK 1747-1824 25 7e-07 20.16 In-house 148-247 (329) Show / Hide 
Range on Protein: 1747-1824
Range on HMM: 148-247/329
Sequence Identity: 25% (26 aa)

KVSYIHRDIKPMNIMIQIDT---------VNEFSVKIIDLGGISKQSKHD------QDDFD------GTIAFYPPEYIQQQ--VTTFD-KSSDVWAIGIC
|  .||||||| ||.|  ..         . .  .|| |  | .|.   |         .       ||  .  |. .|.|     .. . .|.| .|. 
KHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADF-GFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCI

IY
.|
FY
Kinase 9066.AA STE 1590-1697 17 3e-06 18.06 In-house 25-154 (359) Show / Hide 
Range on Protein: 1590-1697
Range on HMM: 25-154/359
Sequence Identity: 17% (25 aa)

FNI-CYISQGSEGKVYKAKMIDRS---YKQFK---------CAIKIIQIAKQ-------------------QEIFQKEIDIRNDINLIEEEYNRLQPNQR
. .   | .|. |.||||. .. .    ....         .|||.. . ..                   .. ..|||.| .. |              
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNH-------------

NEKINPYGIVKYYYDFKTK------EGYQGVVMEYCN-ETLESLMKN
   .    |||||  .  .      ...  ..|||..  .|....|.
---M-HPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKH
Kinase 9066.AA ULK 1666-1697 41 0.001455 8.41 In-house 80-113 (329) Show / Hide 
Range on Protein: 1666-1697
Range on HMM: 80-113/329
Sequence Identity: 41% (14 aa)

IVKYYYDFKTKEG-YQGVVMEYCNE-TLESLMKN
|||.|  |.|.   .   .|||||  .||...|.
IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKK
Kinase 9066.AA CAMK 1594-1638 19 0.002526 5.77 In-house 240-323 (425) Show / Hide 
Range on Protein: 1594-1638
Range on HMM: 240-323/425
Sequence Identity: 19% (16 aa)

YISQGSEGKVYKAKMIDRSYKQ---------FKCAIKIIQ------------------------------IAKQQEIFQKEIDI
 . .|| |||.... .    |.          |.|||||                                .| .. ...||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEI
Kinase 9066.AA ULK 1589-1638 25 0.003502 7.06 In-house 106-168 (329) Show / Hide 
Range on Protein: 1589-1638
Range on HMM: 106-168/329
Sequence Identity: 25% (16 aa)

VFNICYISQGSEGKVYKAK-MID-RSYKQFKCAIKIIQIAKQQEIF------------QKEIDI
   .  . .|| |||||.. ... . |.. |.|.|.|.. |....             ..||.|
YCLNHCLGKGSFGKVYKGRNKKTKD-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKI
Kinase 9066.AA C8 1589-1631 27 0.016728 4.64 In-house 1-40 (226) Show / Hide 
Range on Protein: 1589-1631
Range on HMM: 1-40/226
Sequence Identity: 27% (12 aa)

VFNICYISQGSEGKVYKAKMIDRSYKQFKCAIKIIQIAKQQEI
. |  |.|.|. | | ||| .. . ..  ...|. ..  .|.|
FNNFQYLSFGAYGMVLKAKNVK-DNRE--IVLKFQKCQNKQDI
Kinase 9066.AA TKL 1595-1607 53 0.09436 2.1 In-house 55-67 (364) Show / Hide 
Range on Protein: 1595-1607
Range on HMM: 55-67/364
Sequence Identity: 53% (7 aa)

ISQGSEGKVYKAK
| .|. |.|||.|
IGSGGFGEVYKGK
Kinase 9066.AA MLK 1589-1636 19 0.158671 1.22 In-house 1-56 (291) Show / Hide 
Range on Protein: 1589-1636
Range on HMM: 1-56/291
Sequence Identity: 19% (11 aa)

VFNICYISQGSEGKVYKAKMIDRS-----YKQFKCAIKIIQIAKQ---QEIFQKEI
  .  .|  || |||.|...  .       .  .... |. ...    |. |..|.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMEC