Gene 8908 (Tetrahymena)
8908
Sequence
Protein domains of 8908.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 8908.AA | C8 | 42-150 | 55 | 3.3e-48 | 165.38 | In-house | 1-109 (226) | Show / Hide |
Range on Protein: 42-150 Range on HMM: 1-109/226 Sequence Identity: 55% (61 aa) FKNFEYLSSGAYALLLKAQNSQQNRQVALKFIGSSNQEDKNGIESLKKEYEMLQKFSQSEFLVNVYDCFYLMEEKEDEDADGNDIIVQTEVKSFFVMEME |.||.|||.|||.. |||.|...||...||| ..|..|...|||..|||||.|.|.|..|.||.|||||.|.|...|. ..|..|||||.||.|||||| FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME LCEIVWKRL ||| | | LCEQNLKQL |
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Kinase | 8908.AA | Ciliate-C8 | 51-144 | 59 | 8.7e-46 | 158.43 | In-house | 1-97 (238) | Show / Hide |
Range on Protein: 51-144 Range on HMM: 1-97/238 Sequence Identity: 59% (58 aa) GAYALLLKAQNSQQNRQVALKFIGSSNQEDKNGIESLKKEYEMLQKFSQSEFLVNVYDCFYLMEEKEDEDADGNDIIVQTEVK---SFFVMEMELCE ||... |||||..|||.|||||. ..|...||..|...|||||...|.|..|.|.||||||||||...|| ||||.||||..| ||||||||.|. GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQ |
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Kinase | 8908.AA | C2 | 51-144 | 37 | 1.1e-26 | 88.23 | In-house | 1-102 (245) | Show / Hide |
Range on Protein: 51-144 Range on HMM: 1-102/245 Sequence Identity: 37% (39 aa) GAYALLLKAQNSQQNRQVALKFIGSSNQEDKNGIESLKKEYEMLQKFSQSEFLVNVYDCFYLMEE-KEDEDADGNDIIVQTEV--------KSFFVMEME || .| ||| | .|||.|||| | .. | || ... |||....... . ....||..||| .. ||||| | ...... | |.|.|.|.| GAFGLVLKAFNKKQNRHVALK-IQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE LCE |. FCQ |
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Kinase | 8908.AA | STE20 | 42-115 | 16 | 2.2e-08 | 27.04 | In-house | 1-82 (288) | Show / Hide |
Range on Protein: 42-115 Range on HMM: 1-82/288 Sequence Identity: 16% (14 aa) FKNFEYLSSGAYALLLKAQNSQQNRQ----VALKFIGSSNQEDK-NGIESLKKEYEMLQKFSQSEFLVNVYDCFYLM----EE ....| . .|.| || . . ... || | . ...... . .|...||. ..... .. |. |.... . .| YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDE |
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Kinase | 8908.AA | Ciliate-E1 | 48-112 | 22 | 4.9e-08 | 22.74 | In-house | 1-66 (202) | Show / Hide |
Range on Protein: 48-112 Range on HMM: 1-66/202 Sequence Identity: 22% (15 aa) LSSGAYALLLKA-QNSQQNRQVALKFIGSSNQEDKNGIESLKKEYE-MLQKFSQSEFLVNVYDCFYL ...| ... .|| |......|||.|.| ....| .....||| ... | . . .....|.... IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKI |
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Kinase | 8908.AA | STE | 42-119 | 16 | 2e-06 | 18.98 | In-house | 1-111 (359) | Show / Hide |
Range on Protein: 42-119 Range on HMM: 1-111/359 Sequence Identity: 16% (18 aa) FKNFEYLSSGAYALLLKAQNS------QQNRQ---------VALKFIGSSNQE----------DKNG----IESLKKEYEMLQKFSQ-SEFLVNVYDCFY ... | . .||. || | . ... .| | . .|.. ..| .....|| ....|... ... |. |.|.. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF LM---EEKEDE .. .|| KEGHNHKNDDE |
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Kinase | 8908.AA | Ciliate-E2 | 42-116 | 14 | 4e-06 | 16.91 | In-house | 1-107 (365) | Show / Hide |
Range on Protein: 42-116 Range on HMM: 1-107/365 Sequence Identity: 14% (16 aa) FKNFEYLSSGAYALLLKAQNSQQNRQVALKFIGSSN------------------QEDKNGIESLKKEYEMLQ---------------KFSQSEFLVNVYD .| . . .|... |... ....|.|.|.| . . ||.||..|.| ... .. .. .... |. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE CFYLMEEK ||. . .. CFQEKDDN |
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Kinase | 8908.AA | CMGC | 42-111 | 16 | 5e-06 | 14.7 | In-house | 1-108 (513) | Show / Hide |
Range on Protein: 42-111 Range on HMM: 1-108/513 Sequence Identity: 16% (18 aa) FKNFEYLSSGAYALLLKAQN--------------SQQNRQVALKFI--GSSNQED------KNGIE-SLKKEYEMLQKFS---------------QSEF- ... ... .|.|. |... . |..||.| | ..|. |.|. . | ..|.... . . YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN LVNVYDCFY .|. ||.|| IVKLYDIFY |
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Kinase | 8908.AA | ULK | 42-111 | 21 | 1.6e-05 | 15.62 | In-house | 1-85 (324) | Show / Hide |
Range on Protein: 42-111 Range on HMM: 1-85/324 Sequence Identity: 21% (18 aa) FKNFEYLSSGAYA-LLLKAQNSQQ---NRQVALKFIGSSNQEDKNG-------IESLKKEYEMLQKFS--QSEF--LVNVYDCFY . . | .|... |. | .. | .|| | | ... .|. ...||.| . ..|. .... | ||.|. YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFE |
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Kinase | 8908.AA | CDK | 42-111 | 24 | 9.1e-05 | 11.0 | In-house | 1-77 (284) | Show / Hide |
Range on Protein: 42-111 Range on HMM: 1-77/284 Sequence Identity: 24% (19 aa) FKNFEYLSSGAYALLLKAQNSQQN-----RQVALKFIGSSN---QEDKNGIE-SLKKEYEMLQKFSQSEFLVNVYDCFY .. | . |.|. ||.. |.. . |||| | | .|.| |. . | .|.. . |...|... YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCH |