Gene 8837 (Tetrahymena)
8837
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 8837.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 8837.AA | GSK | 190-298 | 19 | 1.8e-11 | 30.66 | In-house | 201-328 (328) | Show / Hide |
Range on Protein: 190-298 Range on HMM: 201-328/328 Sequence Identity: 19% (25 aa) DLWGLGCIFAEIFFCQAPIFSSSSLEQQAFSYYLVLGIPEKEEAYYIQENHHQQLCDLLIEKAKYEDLPILK------------------HIMNK--VQQ | | .||..|| . | |.|. | |.. . .|| | ||. .. ... .. . .... .... |. | .... . DVWSCGCVMAEMLKGQ-PLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFK-FPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDM K-QSEILTSLLEFHPQNRVSCVNLLKYPFF . . . ....|...|..| | ... ||| QDWIDLISKCLVYDPKKRLSPLEACAHPFF |
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| Kinase | 8837.AA | CMGC | 190-298 | 14 | 9.4e-10 | 27.27 | In-house | 317-513 (513) | Show / Hide |
Range on Protein: 190-298 Range on HMM: 317-513/513 Sequence Identity: 14% (29 aa) DLWGLGCIFAEI-------FFCQAPIFSSSSL-----------EQQAFSYYLVLGIP----------------EKEEAYYIQENHHQQ------------ | |..||||||. | |.| .| | | ||| | |.| ..|. .... DMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTN -LCDL----------LIEKAKYEDLPILKHIMN-------------------------------KVQQKQSEILTSLLEFHPQNRVSCVNLLKYPFF ... . .. . .. . . | . .. . | .|.. |..| .. |. |.| HWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF |
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| Kinase | 8837.AA | CDK5 | 190-298 | 25 | 1.4e-09 | 25.95 | In-house | 181-287 (287) | Show / Hide |
Range on Protein: 190-298 Range on HMM: 181-287/287 Sequence Identity: 25% (29 aa) DLWGLGCIFAEIFFCQAPIFSSSSLEQQAFSYYLVLGIPEKEEAYYIQENHHQQLCDLL---IEKAKYEDLPILKHIMNKVQQKQSEILTSLLEFHPQNR |.| ||||||. | | .. | | . . ..| | .. | .| | . .|. . .. | | .| ..| .|.. |. | DMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSI-----TKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQR VSCVNLLKYPFF .| . |. |.| ISAKAALHHPYF |
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| Kinase | 8837.AA | MAK | 260-298 | 30 | 4.8e-08 | 21.23 | In-house | 313-352 (352) | Show / Hide |
Range on Protein: 260-298 Range on HMM: 313-352/352 Sequence Identity: 30% (12 aa) LKHIMNKVQQ-KQSEILTSLLEFHPQNRVSCVNLLKYPFF |||.... .| .|... .|.. |. | ..|||.| LKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF |
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| Kinase | 8837.AA | ERK7 | 190-298 | 21 | 1.6e-07 | 21.5 | In-house | 189-292 (292) | Show / Hide |
Range on Protein: 190-298 Range on HMM: 189-292/292 Sequence Identity: 21% (23 aa) DLWGLGCIFAEIFFCQAPIFSSSSLEQQAFSYYLVLGIPEKEEAYYIQENHHQQLCDLLIEKAKYEDLPILKHIMNKVQQKQSEILTSLLEFHPQNRVSC |.|..||| .|. . |.| .| | ... | .|. |. . .. . .... ... |...| . .. ..| || | |..|.. DMWSIGCILGEM-LRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKT----LDQMMPQCCDDAIDLLKRLLVFNPKKRLTA VNLLKYPFF . |. |. EQALQHPYV |
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| Kinase | 8837.AA | PFTAIRE | 190-298 | 21 | 2.1e-07 | 22.08 | In-house | 180-287 (287) | Show / Hide |
Range on Protein: 190-298 Range on HMM: 180-287/287 Sequence Identity: 21% (24 aa) DLWGLGCIFAEIFFCQAPIFSSSSLEQQAFSYYLVLGIPEKEEAYYIQENHHQQLCDLLIEKAK--YEDLPILKHIMNKVQ--QKQSEILTSLLEFHPQN |.|| |||| | . |. . | . ||| | . . . | .... |.|...... . .... .| |.. DMWGVGCIFVEMMWGQPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCH-----LPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRD RVSCVNLLKYPFF ||| .. .. |.| RVSAQEAMQHPYF |
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| Kinase | 8837.AA | nmo | 190-298 | 27 | 3.4e-07 | 17.51 | In-house | 186-292 (292) | Show / Hide |
Range on Protein: 190-298 Range on HMM: 186-292/292 Sequence Identity: 27% (30 aa) DLWGLGCIFAEIFFCQAPIFSSSSLEQQAFSYYLVLGIPEKEEAYYIQENHHQQLCDLLIEKAKYEDLPILKHIMN--KVQQKQSEILTSLLEFHPQNRV |.| ||||||. . | ..| . | || | |. | | .. .| . | .|. | .. . ..| .| | |. |. DIWSVGCIFAELLGRRILFQAQSPIQQLQMITDL-LGTPSMEDMKYACEGAKAH---MLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRI SCVNLLKYPFF || . |. |. SCKDALAHPYL |
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| Kinase | 8837.AA | PCTAIRE | 253-298 | 31 | 5e-06 | 17.33 | In-house | 244-291 (291) | Show / Hide |
Range on Protein: 253-298 Range on HMM: 244-291/291 Sequence Identity: 31% (15 aa) KYEDLPILKH--IMNKVQQKQSEILTSLLEFHPQNRVSCVNLLKYPFF .| .|.. | . |. .. . ||.|| . ..|||| . .| |.| RYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF |
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| Kinase | 8837.AA | CDK7 | 273-298 | 26 | 5e-06 | 11.67 | In-house | 263-288 (288) | Show / Hide |
Range on Protein: 273-298 Range on HMM: 263-288/288 Sequence Identity: 26% (7 aa) EILTSLLEFHPQNRVSCVNLLKYPFF . . .. . |..|..|. || |.| DLMCGMWTMNPCKRWTCTQCLKMPYF |
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| Kinase | 8837.AA | CDK | 273-298 | 30 | 0.000122 | 10.59 | In-house | 259-284 (284) | Show / Hide |
Range on Protein: 273-298 Range on HMM: 259-284/284 Sequence Identity: 30% (8 aa) EILTSLLEFHPQNRVSCVNLLKYPFF . | ..| . |..|.|. |. |.| DLLNKMLCYDPKKRISAEQALQHPYF |
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| Kinase | 8837.AA | CDK | 190-202 | 69 | 0.000397 | 8.92 | In-house | 204-216 (284) | Show / Hide |
Range on Protein: 190-202 Range on HMM: 204-216/284 Sequence Identity: 69% (9 aa) DLWGLGCIFAEIF |.|..||||||.| DMWSVGCIFAEMF |
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| Kinase | 8837.AA | PCTAIRE | 188-201 | 64 | 0.005105 | 6.39 | In-house | 178-191 (291) | Show / Hide |
Range on Protein: 188-201 Range on HMM: 178-191/291 Sequence Identity: 64% (9 aa) QTDLWGLGCIFAEI | | || ||||.|. QIDMWGVGCIFYEM |
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| Kinase | 8837.AA | CDK7 | 190-200 | 72 | 0.007331 | 2.97 | In-house | 185-195 (288) | Show / Hide |
Range on Protein: 190-200 Range on HMM: 185-195/288 Sequence Identity: 72% (8 aa) DLWGLGCIFAE |.| |||||| DMWSVGCIFAE |
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