7644

Species: Tetrahymena
Alias: PreTt07644, 1043, 1676.m00002, TTHERM_02472150, 7644
External Links: Tetrahymena Genome Database (TGD) ,
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
7644.AA Protein None 232 None Fasta, JSON
7644.kin_dom Protein Kinase Domain None 129 None Fasta, JSON
7644.NA RNA None 696 None Fasta, JSON

Protein domain

Protein domains of 7644.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7644.AA Ciliate-C8 2-149 47 4.4e-54 185.99 In-house 101-238 (238) Show / Hide
Range on Protein: 2-149
Range on HMM: 101-238/238
Sequence Identity: 47% (78 aa)

NLKQLFDFFRNTQ-PPPNEIKEVIAIQMLEGLNNLHVKNIMHRDIKPHNYLVSPSQTYGFTIKLCKKFQLSLNLSIQKIIKTKGDLGFASTVTKSKSHYL
||||.||..|..| .| ...||.|||||....|.||..|||||||||||.||...|.|..|||||. |     . .|      .|.|||| ..|.||||.
NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCD-F-----K-KQ------CDFGFASQLPKNKSHYH

SKK--GTDAY-----------FAPEVEKGQSRIQ--VFKQNQSLNYQFNFNAQKSDIFSLGLVL
|||  |||.|           |||||||.|||||  .|  .             ||..|.||||
SKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKK-------------SDSYSVGLVL

Kinase 7644.AA C8 1-121 52 8.8e-49 167.41 In-house 104-216 (226) Show / Hide
Range on Protein: 1-121
Range on HMM: 104-216/226
Sequence Identity: 52% (69 aa)

ENLKQLFDFFRNTQPP-PNEIKEVIAIQMLEGLNNLHVKNIMHRDIKPHNYLVSPSQTYGFTIKLCKKFQLSLNLSIQKIIKTKGDLGFASTVTKSKSHY
.|||||.|..||.| . ..|.|| |||||..|.|..|.||||||||||||.|| ..|.|||.||||                   |.||||.|.|.|||.
QNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLC-------------------DFGFASQVSKNKSHI

LSKK----GTDAYFAPEVEKG------QSRIQ
.|||    ||.||||||.||.      |.|||
QSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQ

Kinase 7644.AA C2 2-162 29 8.2e-24 78.32 In-house 104-245 (245) Show / Hide
Range on Protein: 2-162
Range on HMM: 104-245/245
Sequence Identity: 29% (52 aa)

NLKQLFDFFRNTQ-PPPNEIKEVIAIQMLEGLNNLHVKNIMHRDIKPHNYLVSPSQTYGFTIKLCK---KFQLSLNLSIQKIIKTKGDLGFASTVTKSKS
|||| |.  |. .  | ...|...||||. . | || ..| |||||| | |.. .|    |||||    ..|                            
NLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKK--------------------------

HYLSKKGTDAYFAPEVEKGQSRIQVFKQNQSLNY---------QFNFNAQKSDIFS-LGLVLLELDNLNVLNDNW
       .|  ||  ... .||| . |.. .  |         . |    .||.|| .|.||||||| .  . . 
-------CDFDFASKLKYNKSRIHFSKFKWTQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC

Kinase 7644.AA PEK 24-152 18 1.4e-12 39.44 In-house 432-587 (655) Show / Hide
Range on Protein: 24-152
Range on HMM: 432-587/655
Sequence Identity: 18% (34 aa)

IAIQMLEGLNNLHVKNIMHRDIKPHNYLVSPSQTYGFTIKLCKKFQLSLNLSIQKIIKTKGDLGFAS-----------------------TVTKSKSHYL
|. |.||||| .| . ..|||.||.|.... ... ..                 ...|  || | |                           .....  
IFRQILEGLNYIHSQGMIHRDLKPSNIFLDCDGQHHQ-----------------MQVKI-GDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNT

SKK----------------------------------GTDAYFAPEVEKGQSRIQVFKQNQSLNYQFNFNAQKSDIFSLGLVLLEL
...                                  ||  | .||...||            .||  .  .|.|..|||....|.
NQQNSPTGQDTHMWSNNYHIQPTSMFYCEHCHHTGGVGTCLYMSPEQLSGQ------------HYQKSHYNHKVDMYSLGIIFFEM

Kinase 7644.AA CDK-DD1 27-54 57 4.9e-12 32.83 In-house 106-133 (379) Show / Hide
Range on Protein: 27-54
Range on HMM: 106-133/379
Sequence Identity: 57% (16 aa)

QMLEGLNNLHVKNIMHRDIKPHNYLVSP
| |||.| .|.  |||||||| | |. .
QLLEGINECHNQGIMHRDIKPANLLINN

Kinase 7644.AA Ciliate-B2 27-61 37 6e-12 24.28 In-house 112-146 (197) Show / Hide
Range on Protein: 27-61
Range on HMM: 112-146/197
Sequence Identity: 37% (13 aa)

QMLEGLNNLHVKNIMHRDIKPHNYLVSPSQTYGFT
|...||  ....||.| |||| | |.. .  | ..
QLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYC

Kinase 7644.AA Ciliate-E1 24-78 35 9e-11 31.73 In-house 114-169 (202) Show / Hide
Range on Protein: 24-78
Range on HMM: 114-169/202
Sequence Identity: 35% (20 aa)

IAIQMLEGLNNLHVKNIMHRDIKPHNYLVSPSQTYGFT-IKLCKKFQLSLNLSIQK
|..|...||. || .||.||||||.| |.. .  | .. . ..|..... | ..|.
IIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQY

Kinase 7644.AA Ciliate-A1 6-52 39 7.2e-09 26.27 In-house 88-134 (301) Show / Hide
Range on Protein: 6-52
Range on HMM: 88-134/301
Sequence Identity: 39% (19 aa)

LFDFFRNTQ-PPPNEIKEVIAIQMLEGLNNLHVKNIMHRDIKPHNYLV
||... .       || | |  |. ||.  .| .||.|||.|| | |.
LFNYCYQNDYMKKEEIYE-ICYQIIEGYADIHDHNILHRDLKPQNILI

Kinase 7644.AA Ciliate-E5 27-54 50 3.9e-07 19.06 In-house 111-138 (271) Show / Hide
Range on Protein: 27-54
Range on HMM: 111-138/271
Sequence Identity: 50% (14 aa)

QMLEGLNNLHVKNIMHRDIKPHNYLVSP
|   ||. .| ||| | ||||.| | ..
QLVKGLQDIHQKNIIHLDIKPANILLGY

Kinase 7644.AA Dicty3 95-151 28 1e-06 17.53 In-house 248-289 (351) Show / Hide
Range on Protein: 95-151
Range on HMM: 248-289/351
Sequence Identity: 28% (16 aa)

SKSHYLSKKGTDAYFAPEVEKGQSRIQVFKQNQSLNYQFNFNAQKSDIFSLGLVLLE
.|. . |  ||. |.|||. .. .                    ||||.|||....|
YKQKCYSICGTIHYMAPEIKLNNQCC---------------ACRKSDIWSLGCTVWE

Kinase 7644.AA Pkinase 3-49 32 4e-06 22.62 Pfam 86-138 (293) Show / Hide
Range on Protein: 3-49
Range on HMM: 86-138/293
Sequence Identity: 32% (18 aa)

LKQLFDFF------RNTQP--PPNEIKEVIAIQMLEGLNNLHVKNIMHRDIKPHN
|. ..| |      |..    ...|.| ..  |.|.||. .| ..|.|||.|| |
LY-VMDLFDYISTWRHGCFYFSEWECKFYMY-QILRGLEYCHSMGIIHRDLKPEN

Kinase 7644.AA Dicty3 16-49 37 1.1e-05 14.54 In-house 109-142 (351) Show / Hide
Range on Protein: 16-49
Range on HMM: 109-142/351
Sequence Identity: 37% (13 aa)

PPNEIKEVIAIQMLEGLNNLHVKN-IMHRDIKPHN
.. ||...| .. ...|| .| .. |.|||||. |
NEHEISKII-CDLVKTLNYIHKNCHIIHRDIKCDN

Kinase 7644.AA Ciliate-E5 139-153 66 2.7e-05 12.94 In-house 257-271 (271) Show / Hide
Range on Protein: 139-153
Range on HMM: 257-271/271
Sequence Identity: 66% (10 aa)

KSDIFSLGLVLLELD
.|||.|||.| ||| 
QSDIYSLGIVFLELT

Kinase 7644.AA S_TKc 1-215 12 7.1e-05 -105.42 SMART 19-231 (231) Show / Hide
Range on Protein: 1-215
Range on HMM: 19-231/231
Sequence Identity: 12% (37 aa)

ENLK----------------------------------------------------QLFDFFRNTQP-------PPNEIKEVIAIQMLEGLNNLHVKNIM
 . |                                                     |||. .. ..       |. ... ... |....|. .| ..|.
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY-QICCALEYCHSHGII

HRDIKPHNYLVSPSQTYGFTIKLC-----KKFQLSLNLSIQKIIKTKGDLGFASTVTKSKSHYLSKKGTDAYFAPEVEKGQSRIQVFKQNQSLNYQFNFN
|||.|| | |..       .||.|     ...                                .  ||  | ||||                     ..
HRDLKPENILLDE------HIKICDFGLARQL-------------------------------TTFCGTPWYMAPEVL-------------------GYG

AQKSDIFSLGLVLLELDNLNVLNDNWIDLETKAEIYKGKAIASKYQIDRKSNIYKIAEICLKPNYLERKSIGDLLY--------ELI
  |.|. |.| .| |.     . .      . ....|             .    . . ||. .  .| .. ..|         . .
KCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 7644.AA C8 132-149 50 0.000245 11.09 In-house 209-226 (226) Show / Hide
Range on Protein: 132-149
Range on HMM: 209-226/226
Sequence Identity: 50% (9 aa)

QFNFNAQKSDIFSLGLVL
|. ..  .||.||.||||
QYKQYRIQSDLFSVGLVL

Kinase 7644.AA Ciliate-B2 139-146 62 0.000445 5.37 In-house 190-197 (197) Show / Hide
Range on Protein: 139-146
Range on HMM: 190-197/197
Sequence Identity: 62% (5 aa)

KSDIFSLG
.|||.|.|
QSDIYSMG

Kinase 7644.AA Ciliate-A1 139-152 42 0.002091 7.38 In-house 208-221 (301) Show / Hide
Range on Protein: 139-152
Range on HMM: 208-221/301
Sequence Identity: 42% (6 aa)

KSDIFSLGLVLLEL
.||..|||.....|
QSDMYSLGCIICFL

Kinase 7644.AA Pkinase 84-152 25 0.013866 10.22 Pfam 154-205 (293) Show / Hide
Range on Protein: 84-152
Range on HMM: 154-205/293
Sequence Identity: 25% (18 aa)

GDLGFASTV-TKSKSHYLSKKGTDAYFAPEVEKGQSRIQVFKQNQSLNYQFNFNAQKSDIFSLGLVLLEL
.| |.|  . . ..| . .  ||  | ||||      |.            .   .|.|..|.|..| |.
CDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV------IR----------GGQYYGPKVDMWSCGCILYEM