Gene 30187 (Tetrahymena)

30187

Species: Tetrahymena
Alias: 30187, TTHERM_00326840, 3705.m00028, 473, PreTt30187, 33.m00199
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
30187.AA Protein None 701 None Fasta, JSON
30187.kin_dom Protein Kinase Domain None 341 None Fasta, JSON
30187.NA RNA None 2106 None Fasta, JSON

Protein domain

Protein domains of 30187.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 30187.AA AGC 93-433 23 1.2e-84 218.05 In-house 1-395 (395) Show / Hide 
Range on Protein: 93-433
Range on HMM: 1-395/395
Sequence Identity: 23% (105 aa)

YEKIREIGRGAYGIVHKVRNK-------RGQYLAMKEINQTK---LNKDKKAHQIYME-------------KIMKYFK----------FPGIPE-LYSCF
.| .. ||.|..| |. || |        |.| ||| ..  .   ..| .. .... |             .|..  .           | |   |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

RDKSQSTIYIVMAYAE---------GG-QFQRIIKK--YHQYFTFEVVQFFVAE-------MVLILEYIHS-LGFSHRD-FKPENLVLTKDGHLQLIDFG
 ||. . .|.|| |..         ||  .  ....    ..|. |...|. ||       .|| |||.|| .|. |||  ||||..|..|||. | |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

TLNDYCKKLIPQGAIDEVRIK-----DDYRRQKFEREKIREIKMRQQEAIHNHEMGNADAPNINQTSLNDGILQPSDIEEIEQR------------LRSQ
     ||...  | ...  ..         ..|. . |.   .|  . .                             .. ...             | .
L----CKEGMNDGEKGQQ-SQSNMKFHW-HNKKY-Q-KS---NMD-T-N-----------------------K-CNPNNWQRNNMSQEDDTTRKKRDRTW

TFCG--TAEYLCPEMLEDDVCYMNGDLWA--LGCIIYKIFTNNTPFVDS----------QEFLIFNKIKQGI---YNKNH------------EQIPPVAN
||||  |.||. ||.|    .    | |.  |||..|   |  .|| .           ... .|.||. |.    .| .            ... | | 
TFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAK

DLISKLLVLDQYERLGSVVVDENITKETVHEAYKKLKSHPFF
|||.|||. |  .|||.   |..       . .. .|.||.|
DLIKKLLCKDPEKRLGCGGNDFG-D-----KGAEEIKNHPWF
Kinase 30187.AA PDK1 93-433 28 2.3e-76 233.32 In-house 1-307 (307) Show / Hide 
Range on Protein: 93-433
Range on HMM: 1-307/307
Sequence Identity: 28% (104 aa)

YEKIREIGRGAYGIVHKVRNKRG-----QYLAMKEINQTKLNKDKKAHQIYMEK-IMKYFK-----FPGIPELYSCFRDKSQSTIYIVMAYAEGGQFQRI
.  ...||.|.|..| ..|.|       .  | |  .   ... ||. ..  || || .       .|||  ||  |.|  .. .| |. |...| .   
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQD--EQCLYFVLEYCPNGDLLHY

IKKY-HQYFTFEVVQFFVAEMVLILEYIHSLGFSHRDFKPENLVLTKDGHLQLIDFGTLNDYC--KKLIPQG-AIDEVRIKDDYRRQKFEREKIREIKMR
.||     |   ...|..|| ...||..||.|  ||| ||||. |.||.|....||||    .   |..| .  ..  ...  .                
MKKQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGT----AGFDKILPEYQSQQQNQFQQQFQ---------------

QQEAIHNHEMGNADAPNINQTSLNDGILQPSDIEE---IEQRLRSQTFCGTAEYLCPEMLEDDVCYMNGDLWALGCIIYKIFTNNTPFVDS-----QEFL
                            | .. ..   . .. |. .|.||||| .||.|.|  |    |.||||||||  .. ..||...      |..
----------------------------QHNKGMDKPEEDKQTRCKSFVGTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYH

IFNKIKQGIYNKNHE-QIPPVANDLISKLLVLDQYERLGSVVVDENITKETVHEAYKKLKSHPFF
.|.||.   |       .||.| ||..||||.|...||.|   ||        . |. .| ||||
TFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTS--CDE-------CGGYQQIKAHPFF
Kinase 30187.AA S_TKc 93-433 25 2.1e-56 194.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 93-433
Range on HMM: 1-231/231
Sequence Identity: 25% (91 aa)

YEKIREIGRGAYGIVHKVRNKR-GQYLAMKEINQTKLNKDKKAHQIYME-KIMKYFKFPGIPELYSCFRDKSQSTIYIVMAYAEG--GQFQRIIKKYHQ-
||..|.||.||.| |.|.|.|. |.. |.|.|.           .|. | .|.|  . | |  || .|.|   . .|.|| |..|  |   ..|||.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

----YFTFEVVQFFVAEMVLILEYIHSLGFSHRDFKPENLVLTKDGHLQLIDFGTLNDYCKKLIPQGAIDEVRIKDDYRRQKFEREKIREIKMRQQEAIH
    .|.  ...|....... |||.||.|. ||| ||||. |..  |. ..|||    .                                         
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------------------------------------

NHEMGNADAPNINQTSLNDGILQPSDIEEIEQRLRSQTFCGTAEYLCPEMLEDDVCYM-NGDLWALGCIIYKIFTNNTPFVDSQEFLIFNKIKQGIYNKN
                                     ||||| .|. ||.|          | |..|||.|  ..  .||   |....|.||.       
------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------

HEQIPPVANDLISKLLVLDQYERLGSVVVDENITKETVHEAYK---KLKSHPFF
    .| | |.|.|.|. |  .|.            |. || .   . |.||.|
----SPEAKDFIRKCLQKDPEKRP------------TA-EALQDEWDIKCHPWF
Kinase 30187.AA Ciliate-E2 93-433 20 1.3e-48 164.95 In-house 1-365 (365) Show / Hide 
Range on Protein: 93-433
Range on HMM: 1-365/365
Sequence Identity: 20% (89 aa)

YEKIREIGRGAYGIVHKVRNKR------------------------GQYLAMKEINQTKLNKDKKAHQIY----------MEK-IMKYFKFPGIPELYSC
|..|. ||.|..|.| |.....                        ... ||| ... ...  |.  .|.          .|| |..  ..| | ..| |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FRDKSQSTIYIVMAYAEGGQFQRIIK------------------KYHQYFTFEVVQ-------FFVAEMVLILEYIHSLG-FSHRDFKPENLVLTKDGHL
| .|....||.|| |..||  . .||                  |  .|.. ...|       |..|...| |||.|| .   ||| ||||...     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

QLIDFGT------LNDYCK-----KLIPQGAIDEVRIKDDYRRQKFEREKIREIKMRQQEAIHNHEMGNADAPNINQTSLNDGILQPSDIEEIEQRLRSQ
 .||||.       |...      |....   |. |   ... |                                                | |    .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD-Q------------------------------------------------IIQQNMFN

TFCGTAEYLCPEMLEDDV---------CYMNGDLWALGCIIYKIFTNNTPFVDSQEFLIFNKIKQGIYNKN-----------------HEQIPPVANDLI
|.|||..|..||.|.                 |.|.||.|.|   ....||        ...|||. .. .                 ...... . |||
TICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLI

SK----LLVLDQYERLGSVVVDENITKETVHEAYKKLKSHPFF
.|    .|. |. .|..                ..... ||.|
KKFGKRMLQKDPEKRIT---------------GWEQILNHPWF
Kinase 30187.AA AktR 93-408 23 6.7e-34 118.95 In-house 1-254 (268) Show / Hide 
Range on Protein: 93-408
Range on HMM: 1-254/268
Sequence Identity: 23% (78 aa)

YEKIREIGRGAYGIVHKVRNK--RGQYLAMKEINQTKLNKDKKAHQIYMEK-IMK-YFKFPGIPELYSCFRDKSQSTIYIVMAYAEGGQFQRIIKKYHQY
.. .. .|.||.| |  |. |   ... ||| |  .|. . ...|....|. ||.   ..|.|  |. || .|  . ....| | .||   ...|| .. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTK--EKLFFIMEYCPGGELFQHLKKKKK-

FTFEVVQFFVAEMVLILEYIHSL-GFSHRDFKPENLVLTKDGHLQLIDFGTLNDYCKKLIPQGAIDEVRIKDDYRRQKFEREKIREIKMRQQEAIHNHEM
|. |...|. |...| ||| |.    . || ||||..| .|||. ..|||  .                                               
FSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-----------------------------------------------

GNADAPNINQTSLNDGILQPSDIEEIE-QRLRSQTFCGTAEYLCPEMLED-DVCYMNGDLWALGCIIYKIFTNNTPFVD-SQEFLIFNKIKQG-IYNKNH
                      .. ..  . . ..|||| ||. |||.   .    . |.||.|. || . | ..|| . .|. ........  .... .
----------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYP

EQIPPVANDLIS-KLLVLDQYERLGS
... . . |||  |||  ....|||.
SYFSSQCKDLIQRKLLCKNPNKRLGY
Kinase 30187.AA RSK 96-433 22 8.4e-33 115.29 In-house 1-278 (278) Show / Hide 
Range on Protein: 96-433
Range on HMM: 1-278/278
Sequence Identity: 22% (82 aa)

IREI---GRGAYGIVHKV-RNKRGQYLAMKEINQTKLNKDKKAHQIYM--EKIMKYFK-FPGIPELYSCFRDKSQSTIYIVMAYAEGGQFQRIIKKYHQY
...    | |.. ...|. . . ||. ||| ... |. . .|.    |   .|..  .  | | .|.  |....   .|..| | .|| . . ..|  . 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGK--LYLIMEYCRGGELFTHLQKEKHF

--FTFEVVQFFVAEMVLILEYIHSLGFSHRDFKPENLVLTK---DGHLQLIDFGTLNDYCKKLIPQGAIDEVRIKDDYRRQKFEREKIREIKMRQQEAIH
  |. . ..|  || || .|..|..|. ||| |||| ...    .||. |.|||     ||..                                     
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFG----FCKQF-------------------------------------

NHEMGNADAPNINQTSLNDGILQPSDIEEIEQRLRSQTFCGTAEYLCPEMLE---DDVCY-MNGDLWALGCIIYKIFTNNTPFVD---SQEFLIFNKIKQ
                             ...  . .|||.|.||. ||||     .. .  . |.| ||...|  .| ..||     ..   |...|..
----------------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQK

GIYNKNHE---QIPPVANDLISKLLVLDQYERLGSVVVDENITKETVHEAYKKLKSHPFF
| .. ...    . . | |||.|.|  |   |||.   |            . .|.||.|
GKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQD-----------AEEIKQHPWF
Kinase 30187.AA Ciliate-E2b 93-238 28 5.5e-31 91.51 In-house 1-148 (272) Show / Hide 
Range on Protein: 93-238
Range on HMM: 1-148/272
Sequence Identity: 28% (43 aa)

YEKIREIGRGAYGIVHKVRN--KRGQYLAMKEINQTKLNKDKKAHQIYMEK-IMKYFKFPGIPELYSCFRDKSQSTIYIVMAYAEGGQFQRIIKKYH-QY
 . | . |.|..| |  |.|  .  ||.||| |.  .. .     .. .|| ...  ..| |  ..  |.|. .  .| .| .  |. .  .|       
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQH--MYFMMEFCNGMELFDVIREIGRLL

FTFEVVQFFVAEMVLILEYIHSLGFSHRDFKPENLVLTKDGHLQLIDFGT
.  ...||..|...|.||| |...  .|| ||||  ....|.. |||.||
LSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGT
Kinase 30187.AA MAST 93-237 33 2.9e-30 89.13 In-house 1-147 (337) Show / Hide 
Range on Protein: 93-237
Range on HMM: 1-147/337
Sequence Identity: 33% (49 aa)

YEKIREIGRGAYGIVHKVRNK-RGQYLAMKEINQTKLNKDKKAHQIYMEK-IMKYFKFPGIPELYSCFRDKSQSTIYIVMAYAEGGQFQRIIKKYHQYFT
.| |. |..|||| | .|..|  ..  ||| ||   . . .   |.  |. | .. . | . .....|        ..|| | ||| .  ... |   . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

FEVVQFFVAEMVLILEYIHSLGFSHRDFKPENLVLTKDGHLQLIDFG
 . ... .|| || |||.|| |  ||| ||.|......||. | |||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase 30187.AA CAMK 98-237 19 2.9e-30 94.15 In-house 1-241 (425) Show / Hide 
Range on Protein: 98-237
Range on HMM: 1-241/425
Sequence Identity: 19% (47 aa)

EIGRGAYGIVHKVRNKRG-------------QYLAMKEINQTKLNK-------------------------DKKAHQIYME-KIMKY-------FKFPGI
..|||..|.|.....|.              |  |.| |. .|| .                         .|. .... | .|||         . | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

PELYSCFRDKS-----------------QSTIYIVM---AYAEGG----Q-FQRIIKKYH-------------QYFTFEVVQFFVAEMVLILEYIHSLGF
  ||  . |..                 .. .|.||    |..||      |..|... .              .|| . .....  ..  ..|.||.. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDFKPENLVLTKD-----------------GHLQLIDFG
 ||| ||||. |...                 . . .||||
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFG
Kinase 30187.AA MAST 93-237 34 3.5e-30 94.25 In-house 1-144 (334) Show / Hide 
Range on Protein: 93-237
Range on HMM: 1-144/334
Sequence Identity: 34% (52 aa)

YEKIREIGRGAYGIVHKVRNKRG-QYLAMKEINQTKLNKDKK--AHQIYMEK-IMKYFKFPGIPELYSCFRDKSQSTIYIVMAYAEGGQFQRIIKKYHQY
.| |. |..|||| | .|..|.. .  ||| |.  | .. .|   .|   |. | .. . | . .....|     . ...|| | ||| .  ... |  |
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIK--KSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQT--KNYLCMVMEYMEGGDCASLLHMYG-Y

FTFEVVQFFVAEMVLILEYIHSLGFSHRDFKPENLVLTKDGHLQLIDFG
|  . ... .||.|| |||.|| |  ||| ||.|......||  | |||
FDEWMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase 30187.AA Pkinase 93-237 33 4.4e-28 100.39 Pfam 1-157 (293) Show / Hide 
Range on Protein: 93-237
Range on HMM: 1-157/293
Sequence Identity: 33% (53 aa)

YEKIREIGRGAYGIVHKVRNKRGQY-LAMKEINQTKLNKDKKAHQIY-ME-KIMKYFKFPGIPELYSCFRDKSQSTIYIVMAYAEGG----QFQRIIK-K
|...| ||.|..| | | ..|  .   |.|.|.  . ...|. . .  .| .||| .. | | .|| .|.|   . ||.|| |.|||       ..|. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

YHQYF--TFEVVQFFVAEMVLILEYIHSLGFSHRDFKPENLVLTKDGHL----QLIDFG
.|  |  . ....|.. ...  |||.|| |. ||| ||||. . ..||.     ..|||
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFG
Kinase 30187.AA Ciliate-E2-Unclassified 93-237 27 2.4e-27 91.9 In-house 1-192 (352) Show / Hide 
Range on Protein: 93-237
Range on HMM: 1-192/352
Sequence Identity: 27% (52 aa)

YEKIREIGRGAYGIVHKVRN-KRGQYLAMKEINQTKLNKDKKAHQ----IYMEKIMKYFK-----------------FPGIPELYSCFRDKSQSTIYIVM
|..|. ||.|..|.|.|... | .|| |||.... . .|.|.  .    .  .|.|.  |                 .| .  .. .. .... .|||||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

AYAEGGQFQRIIKKYHQ----------------YFTFEVVQ-----FFVAEMVLILEYIHSLG-FSHRDFKPENLVLTKDG---HLQLIDFG
 |.|||  . .|||...                 || . ..     |. |. .. |||.|. . . ||| ||||......|   .. .||||
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFG
Kinase 30187.AA Ciliate-E2-Unclassified 318-433 20 2.6e-17 56.65 In-house 218-352 (352) Show / Hide 
Range on Protein: 318-433
Range on HMM: 218-352/352
Sequence Identity: 20% (31 aa)

RSQTFCGTAEYL----CPEMLEDDVCY----MNGDLWALGCIIYKIFTNNTPFVDSQEFL----------------IFNKIKQGIYNKNH-------EQI
...||||| .|.     ||.|.    .       | |.||.|.| . ... || | ..                  ....|||.......        ..
MMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHW

PPVANDLIS----KLLVLDQYERLGSVVVDENITKETVHEAYKKLKSHPFF
.| | |.|.    |.|. .. .|.                 ..... ||.|
SPEAKDFINDLLQKMLKKNPNKRI----------------TFEQILNHPWF
Kinase 30187.AA CAMK 320-406 22 1e-15 46.39 In-house 277-414 (425) Show / Hide 
Range on Protein: 320-406
Range on HMM: 277-414/425
Sequence Identity: 22% (31 aa)

QTFCGTAEYLC-PEMLED-------------DVCY-MNGDLWALGCIIYKIFTNNTPFVDS-------------QEFLIFNKIKQGIYNKNHEQIPPV--
.||||| || . ||.|.                 |    | |..|.| |   .   || ..              .  .| ||..| |.  .....|.  
KTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISC

---------------------ANDLISKLLVLDQYERL
                     . |||.|.|. |  .|.
NYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRM
Kinase 30187.AA MAST 344-433 29 1.3e-14 40.44 In-house 251-337 (337) Show / Hide 
Range on Protein: 344-433
Range on HMM: 251-337/337
Sequence Identity: 29% (30 aa)

DLWALGCIIYKIFTNNTPFVDSQEFL-IFNKIKQ----------GIYNKNHEQIPPVANDLISKLLVLDQYERLGSVVVDENITKETVHEAYKKLKSHPF
| |..| |.| . .  .||...     ||..|..          |  |   ....|.| |||.||| .. ..|||.  .||              |.|||
DWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPN-DDDCMSPEAQDLIKKLLQPNPKKRLGANGADE-------------IKQHPF

F
|
F
Kinase 30187.AA MAST 323-433 30 4.3e-14 41.5 In-house 225-334 (334) Show / Hide 
Range on Protein: 323-433
Range on HMM: 225-334/334
Sequence Identity: 30% (37 aa)

CGTAEYLCPEMLEDDV-CYMNGDLWALGCIIYKIFTNNTPFVDSQEFLIFNKIKQGI-----YNKN-----HEQIPPVANDLISKLLVLDQYERLGSV-V
||| .|. || . .     .  | |..| |.| ...  .||.|.   .||..|..       ..        | ..|.| |||.||| .| ..|||.   
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

VDENITKETVHEAYKKLKSHPFF
.||              |.||||
ADE-------------VKQHPFF
Kinase 30187.AA Pkinase 320-433 17 3.4e-13 47.72 Pfam 169-293 (293) Show / Hide 
Range on Protein: 320-433
Range on HMM: 169-293/293
Sequence Identity: 17% (25 aa)

QTFCGTAEYLCPEMLE-DDVCYMNGDLWALGCIIYKIFTNNTPFVDS------QEFLIFNKIKQGIYNKNHEQI--------------------PPVAND
.||||| .|. || .  .       | |..|||.|  .. ..|| ..       .  ....|.....  . ..                     .. . |
TTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

LISKLLVLDQYERLGSVVVDENITKETVHEAYKKLKSHPFF
.|...| .| ..|..                 . .. ||.|
FIKWCLCKDPKKRPT----------------AEQILQHPWF
Kinase 30187.AA TyrKc 93-317 17 2e-06 -118.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 93-317
Range on HMM: 1-280/280
Sequence Identity: 17% (50 aa)

YEKIREIGRGAYGIVHKVRNKRGQYLAMKEINQTKLNKDKKAHQIYME-KIMKYF--KFPGIPELYSCFRDK-----SQSTIYIVMAYAEGGQFQRIIKK
 ......|.||.|.|.| . |  .  | | ..  .         .. | .||. .  . | |  || . ...     .   ..||| |...|  .  ..|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YHQYFTFEVVQFFVAEMVLILEYIHSLGFSHRDFKPENLVLTKDGHLQLIDFG---TLNDY-----CKKLIPQ----GAID---------EVRIKDDYRR
..  .. .    |        ||.|| .. |||    |  ......    |||    . |.      |. . .    |. .         |.       .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI------N

QK------------------FEREKIREIK-----MRQQEAIHNHEMGNADAPNIN---------QTSLNDGILQ-----PSD---IEEIEQRL
 .                  | . .          |  ||.|.. . |.   .  |          . . . ..|     |.|    .|| ...
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 30187.AA Ciliate-E2b 318-362 24 0.000408 8.59 In-house 161-210 (272) Show / Hide 
Range on Protein: 318-362
Range on HMM: 161-210/272
Sequence Identity: 24% (12 aa)

RSQTFCGTAEYLCPEMLE-----DDVCYMNGDLWALGCIIYKIFTNNTPF
|  | .|| .|. || ..          .. |.|..| . | .     |.
RTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPW
Kinase 30187.AA Ciliate-E2b 424-433 70 0.009568 4.36 In-house 263-272 (272) Show / Hide 
Range on Protein: 424-433
Range on HMM: 263-272/272
Sequence Identity: 70% (7 aa)

YKKLKSHPFF
|. |||||.|
YSWLKSHPWF
Kinase 30187.AA AktR 427-433 71 0.059545 3.84 In-house 262-268 (268) Show / Hide 
Range on Protein: 427-433
Range on HMM: 262-268/268
Sequence Identity: 71% (5 aa)

LKSHPFF
.||||.|
IKSHPWF