Gene 30107 (Tetrahymena)

30107

Species: Tetrahymena
Alias: 30107, 173.m00053, TTHERM_00945280, 859, PreTt30107
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
30107.AA Protein None 304 None Fasta, JSON
30107.kin_dom Protein Kinase Domain None 253 None Fasta, JSON
30107.NA RNA None 915 None Fasta, JSON

Protein domain

Protein domains of 30107.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 30107.AA S_TKc 30-300 21 2.2e-39 138.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-300
Range on HMM: 1-231/231
Sequence Identity: 21% (64 aa)

YETLETISENSDTEVHIQKVKKISDNKVYCAKIFYKNVDIKRGDANEQNEIKYLKKLKHSNIVTIIEYFDDDEKIVIITEYLEI---TLYDVLKCYKK--
|| |..| . .  .|.  . ||  .....  ||            . ..||. ||| .| |||.....|.| ... ...||..    .|.|..| ...  
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSEQDVKIIAKTIFIILDHLQKHNLVHGDLVLQNFMLKKEDDQFDSLKMIDFNTVDTEENRRSTKKITNRTQFLNCQPTS-------LAPETIQQY
    ..| ... ... |.  |... .|. .| ||  .| .| .       .| .||                          |.       .||| .   
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL--------------------TTFCGTPWYMAPEVL---

IVNK-QSDVWSAGIMLYTLLFGTVPFDGKNPEQIYDSILNKQPKYQLEDESGQCVNISQRCESFLKRLLHKNYEHRYSARQALE-------DPWL
  .|  .|.|| |..|| .| |  ||.  ....... |.                  |. . .|....|.|. |.|..| .||.       .||.
GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 30107.AA Ciliate-E2 30-300 19 6.5e-37 124.24 In-house 1-365 (365) Show / Hide 
Range on Protein: 30-300
Range on HMM: 1-365/365
Sequence Identity: 19% (75 aa)

YETLETISENSDTEVHIQKVKKI---------------------SDNKVYCAKIF-YKNVDIKRGDANEQNEIK----------YLKKLKHSNIVTIIEY
|. .. | . .   |   ||.|                       ..| |  ||.  ... ..    .. .||.           |..|.| ||. ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FD--DDEKIVIITEYLEI-TLYDVLK------------CYKKLSEQDVKIIAKTIF---------------IILDHLQKHN-LVHGDLVLQNFMLKKEDD
|   ||..| ...||..  .|.| .|              |...|. .| | | |.                 | .| . |  .| |. ..| ..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

QFDSLKMIDFNTVD--TEENRRSTKKITNRTQFLNCQ-------------------------PTSLAPETIQ---------QYIVNKQSDVWSAGIMLYT
    .| ||| .    ...| . |.    .  ... .                         |  .||| ..         |   ....|.||.|..|| 
----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

LLFGTVPFDGKNPEQIYDSILNKQPKYQLED------ESGQCVN------ISQRCESFLKR----LLHKNYEHRYS-ARQALEDPWL
.|||  ||        .. |.... ... ..      .  | ..      .|| |  ..|.    .| |. | |.. . |.|. ||.
MLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 30107.AA Ciliate-E2-Unclassified 30-300 20 3.5e-29 98.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 30-300
Range on HMM: 1-352/352
Sequence Identity: 20% (73 aa)

YETLETISENSDTEVHIQKVKKISDNKVY------CAKIFYKNVDIKRGDANEQNEIKYLKKLK-------------------HSNIVTIIEYFDDDEKI
|. ...| . .  .|  .|.......  |      . .. ||   |.. | .. ||.| ....|                   | .||  ...| |...|
YKIIKQIGQGGFGKV--YKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNI

VIITEYLE-ITLYDVLKCYKK-----------------LSEQDVK------IIAKTIFIILDHLQKHNLVHGDLVLQNFMLKKED--------DQFDSLK
 |..||.|  .| . .| .||                 ..|| .|      ..|  .  .    .|.| .| |. ..| .....         | . | |
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

MIDFNTVDTEEN-RRSTKKITNRTQFLNCQPTSL----APETIQQYIVN----KQSDVWSAGIMLYTLLFGTVPFDGKNPEQ----------------IY
 ...|  | ...  .    . ....   . |  .    ||| .|.   .    ...|.|| |. || .|||. ||...| ||                .|
YQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY

DSILNKQPKYQLEDESGQCVNISQRCESFLK----RLLHKNYEHRYSARQALEDPWL
. |..|..... ...     ..|. .. |..    ..| || . |... |.|. ||.
QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 30107.AA AGC 205-300 23 2.4e-28 69.06 In-house 274-395 (395) Show / Hide 
Range on Protein: 205-300
Range on HMM: 274-395/395
Sequence Identity: 23% (29 aa)

LAPETIQQYIVNKQSDVWS--AGIMLYTLLFGTVPFDGKNPE----------QIYDSIL------NKQPKYQLED--ESGQCVNISQRCESFLKRLLHKN
.||| .     .|. | ||   |...| .|.|  || |.||.          .....|.      |...|.   .  ..  ....|. . ...|.||.|.
MAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKD

YEHRYS----------ARQALEDPWL
 |.|            | .  . || 
PEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 30107.AA CAMK 206-300 19 3.6e-28 87.27 In-house 288-425 (425) Show / Hide 
Range on Protein: 206-300
Range on HMM: 288-425/425
Sequence Identity: 19% (27 aa)

APETIQQYI--------------VNKQSDVWSAGIMLYTLLFGTVPFDGK-------------NPEQIYDSILNKQPKYQLEDESG--------------
||| ...                .....|.||.|..||..| |. ||.|.             |.....  |.. .  .  .  |.              
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDIS

---QCVNISQRCESFLKRLLHKNYEHRYSARQALEDPWL
   .  ..|| | ......| .. |.|... |.|..||.
DEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 30107.AA CDPK 205-300 34 8e-25 73.24 In-house 181-271 (271) Show / Hide 
Range on Protein: 205-300
Range on HMM: 181-271/271
Sequence Identity: 34% (33 aa)

LAPETIQQYIVNKQSDVWSAGIMLYTLLFGTVPFDGKNPEQIYDSILNKQPKYQLEDESGQCVNISQRCESFLKRLLHKNYEHRYSARQALEDPWL
.||| .|.   |...|.||.|. ||.|| |. || ||| ..|.... . .  |..|..  ..  ||. .    ...| .... |.|| |||..|| 
IAPEVLQKK-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGK--YSFEGPEWDH--ISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 30107.AA Ciliate-E2a 217-300 32 4e-24 67.94 In-house 195-275 (275) Show / Hide 
Range on Protein: 217-300
Range on HMM: 195-275/275
Sequence Identity: 32% (28 aa)

KQSDVWSAGIMLYTLLFGTVPFDGKNPEQIYDSILNKQPKYQLEDES-GQCVNISQRCESFLKRLLHKNYEHRYSARQALEDPWL
.. |.||.|...|.||.|. ||.||. ..|   ..||. |.....    ..  .|. |  ..|..| |. ..|..| |||..|| 
TKCDMWSCGVIFYILLCGKPPFKGKTYNEIL--QQNKKCKIDFNCPECWEK--CSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 30107.AA Pkinase 205-300 25 9.2e-22 78.03 Pfam 178-293 (293) Show / Hide 
Range on Protein: 205-300
Range on HMM: 178-293/293
Sequence Identity: 25% (30 aa)

LAPETIQ-QYIVNKQSDVWSAGIMLYTLLFGTVPFDGK------NPEQIYDSILNKQPKYQLEDE--------------SGQCVNISQRCESFLKRLLHK
.||| |. .    . .|.||.|..|| .|.|  ||.|.      .. |... |. ...... . .              .   .|.|. | .|.|..|.|
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCK

NYEHRYSARQALEDPWL
. . |..|.|.|..||.
DPKKRPTAEQILQHPWF
Kinase 30107.AA STE 77-300 19 2.8e-21 72.0 In-house 76-359 (359) Show / Hide 
Range on Protein: 77-300
Range on HMM: 76-359/359
Sequence Identity: 19% (58 aa)

QNEIKYLKKLK--HSNIVTIIEYFDDD-------EKIVIITEYLE-ITLYDVLK-CYKKLS-------------EQDVKIIAKTIFII-LDHLQKHNLVH
..||| .||..  | |||. . .. ..       ... |. ||..  .| |..| .|...              |. ...|.. |    |..| .|. .|
LKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIH

GDLVLQNFMLKKEDDQFDSLKMIDFNTVD--TEENRRSTKKI-----------TNRTQFLNCQPTSLAPETIQQYIVN------KQSDVWSAGIMLYTLL
 |.  .| .|          | .|| .    |......   .            .|. |  ..    ||| |||   .       ..|.|| |...  ..
RDIKPANILL---------VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA

FGTVPF-DGKNPEQIYDSILNK-------------QPKYQLE-DESGQCV------------NISQRCESFLKRLLHKNYEHRYSARQALE--DPWL
 | .|. |..... ..  . |.             .|  .|. . |  .             . |. .  |... | |....| .| | |.   |..
TGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 30107.AA CAMKL 220-300 22 5.2e-20 60.42 In-house 218-297 (297) Show / Hide 
Range on Protein: 220-300
Range on HMM: 218-297/297
Sequence Identity: 22% (19 aa)

DVWSAGIMLYTLLFGTVPFDGKNPEQIYDSILNKQPKYQLEDESGQC--VNISQRCESFLKRLLHKNYEHRYSARQALEDPWL
|.||.|..||....|..|||. . ..  ..   .  . . ..    .  . .| .|.......| .| |.|... | ...||.
DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 30107.AA MARK 220-300 28 2.6e-19 59.96 In-house 188-262 (262) Show / Hide 
Range on Protein: 220-300
Range on HMM: 188-262/262
Sequence Identity: 28% (24 aa)

DVWSAGIMLYTLLFGTVPFDGKN--PEQIYDSILNKQPKYQLEDESGQCVNISQRCESFLKRLLHKNYEHRYSARQALEDPWL
|.|| |. ||... |..||||..   ...|  ||. ....           .|  |.....|||  | | | .. . ...||.
DIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--------VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 30107.AA RSK 216-300 23 1.6e-16 57.17 In-house 190-278 (278) Show / Hide 
Range on Protein: 216-300
Range on HMM: 190-278/278
Sequence Identity: 23% (22 aa)

NKQSDVWSAGIMLYTLLFGTVPFDG---KNPEQIYDSILNKQ--PKYQLEDESGQCVNISQRCESFLKRLLHKNYEHRYS-----ARQALEDPWL
.|. |.|| |. .|..|.| .|| |   .|...| . |....  ..    .      ..|| . ......||.. . |..     | . ...||.
DKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQ------YLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 30107.AA Pkinase 48-176 24 1.4e-14 52.6 Pfam 17-156 (293) Show / Hide 
Range on Protein: 48-176
Range on HMM: 17-156/293
Sequence Identity: 24% (34 aa)

KVKKISDNKVYCAKIFYKNVDIKRGDANEQN--EIKYLKKLKHSNIVTIIEYFDDDEKIVIITEYLEI-----TLYDVLK--CYKKL--SEQDVKIIAKT
| ......|... ||. |  . .  | .  .  ||...|.|.| |||.....| |. .| ...||.|       |.|...   ....  ||...| ... 
KCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQ

IFIILDHLQKHNLVHGDLVLQNFMLKKEDDQF-DSLKMIDF
|.  |... ... .| || ..|.... ....  ...| .||
ILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDF
Kinase 30107.AA Ciliate-E2a 48-176 27 8.3e-14 37.04 In-house 17-153 (275) Show / Hide 
Range on Protein: 48-176
Range on HMM: 17-153/275
Sequence Identity: 27% (38 aa)

KVKKISDNKVYCAKIFYK-NVDIKRGDANEQNEIKYLKKLKHSNIVTIIEYFDDDEKIVIITEYLE-ITLYDVLKCYKKLSEQ--DVKIIAKTIF-IILD
..... ..| . .|.| | . ..| |... .|||.....|.| ||  ..|.. |.  . ...||.|  .||| .|  |.. |   ... | . ..   | 
LAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLH

HLQKHNLVHGDLVLQNFMLK---KEDDQFDSLKMIDF
.... | .| || ..|...|   |...|   .|.|||
YMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDF
Kinase 30107.AA CAMK 77-176 19 4e-13 37.93 In-house 79-240 (425) Show / Hide 
Range on Protein: 77-176
Range on HMM: 79-240/425
Sequence Identity: 19% (32 aa)

QNEIKYLKK-------LKHSNIVTIIEYFDD-------------------DEKIVIIT---EYL---EI--TLYDVLKCY---------------KKLSE
..||. .||       |.| ||. ..|...|                   |.......   ||    |    |.| ..                 ....|
RREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTE

QDVKIIAKTIFIILDHLQKHNLVHGDLVLQNFMLKKEDDQFD-------------SLKMIDF
.... . . |   .... .|| || || . | .| . .| .|              .| |||
REARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase 30107.AA CAMKL 73-176 20 2.4e-10 29.1 In-house 42-173 (297) Show / Hide 
Range on Protein: 73-176
Range on HMM: 42-173/297
Sequence Identity: 20% (27 aa)

DANEQN--------------EIKYLKKLK---HSNIVTIIEYFDDDEK------IVIITEYLEIT---LYDVL---KCYK-KLSEQDVKIIAKTIFIILD
. ...|              ||. .|.|.   | ||. . | ....|.      |....|| .     |.| .   .. . ...| . . . . |   ..
PWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVN

HLQKHNLVHGDLVLQNFMLKKEDDQFDSLKMIDF
.. .|. || |. . | .| . ...   .| |||
YCHSHGIVHRDIKPENILLDENGNN--NIKIIDF
Kinase 30107.AA TyrKc 46-298 19 5.2e-07 -109.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 46-298
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

IQKVKKISD---NKVYCAKIFYKNVDIKRGDANE----QNEIKYLKKL--KHSNIVTIIEYFDDD-------EKIVIITEYLE-ITLYDVLKCYKK-LSE
|.. ||.      .|| ..    .| .|   ..      .|.. ..||  .| ||| .. .  ..       | . |..|| .   | | |. ... |. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM

QDVKIIAKTIFIILDHLQKHNLVHGDLVLQNFMLKKEDDQFDSLKMIDF----NTVDT-------EENRRST---KK--ITNRTQFLNCQPTSLAPETIQ
.|   ..  |    ..| ..|..| ||   | .....       |  ||    .  |        .  | ..   .|  .  |          .|||.|.
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW---------MAPECIN

QYIVNKQSDVWSAGIMLY-TLLFGTVPFDG-----KNPEQIYDSILNKQPKYQLED----ESGQCVNISQRCESFLKRLLHKNYEHRYSARQALEDP
 .. . .||||| |....  . .|  |  |     .......  . .     | ..     .   |  ..   .  |.  | . | | . ..  |. 
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 30107.AA MARK 77-112 30 6e-06 15.62 In-house 47-85 (262) Show / Hide 
Range on Protein: 77-112
Range on HMM: 47-85/262
Sequence Identity: 30% (12 aa)

QNEIKYLKKLKHSNIVTIIEYFD--DDEK-IVIITEYLE
. ||...|||.| ||.   ....  . .. |..| || .
MREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYAS
Kinase 30107.AA RSK 49-176 23 1.7e-05 16.46 In-house 15-151 (278) Show / Hide 
Range on Protein: 49-176
Range on HMM: 15-151/278
Sequence Identity: 23% (32 aa)

VKKI---SDNKVYCAKIFYK-NVDIKRGDANEQN-EIKYLKKLK-HSNIVTIIEYFDDDEKIVIITEYLE-ITLYDVLKCYKK---LSEQDVKIIAKTIF
..|.     ...|  |.  |  .. .  |.     |.. |.  . | .|||  . |....|. .|.||..   |.. |.  |    .|| ...... .| 
CRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIV

IILDHLQKHNLVHGDLVLQNFMLKKEDDQFDSLKMIDF
  ..|| ..  .| || . | ..  |. .  ..| .||
LAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDF
Kinase 30107.AA CDPK 77-112 39 0.051634 2.21 In-house 49-86 (271) Show / Hide 
Range on Protein: 77-112
Range on HMM: 49-86/271
Sequence Identity: 39% (15 aa)

QNEIKYLKKLKHSNIVTIIEYFDDDEKIVIITE--YLE
.|||. ||.| | ||. | |.. |.  . |..|  |..
FNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCT