Gene 29028 (Tetrahymena)
29028
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 29028.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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S_TKc | 29028.AA | S_TKc | 23-274 | 17 | 3e-11 | -11.89 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 23-274 Range on HMM: 1-231/231 Sequence Identity: 17% (47 aa) LSQSNYIAEGRLGRVYSYIKKKTGEAFAVQIMQNLDRQTRFNVMEEIRTIYSEIHTRKGGQLETYS---LHLIME-IGY---SLLHIMKQQPD------M . | .| |.|| ..||||. .|. |. ... ||. . | .... |...|| .. .|....|... . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF SMKDILYHFKNIIKIIVKLHSNKLYHGNLKPQNILYIEEKNSIGGKTKKLKFSGFFNTKKGQKTYT---PYTPKDLVSQWKNYDRINGNYLL-LGDIYSI . .. . .. |.. . .||.. | |||.||| | .| . | .. .|. | . .. | |..|. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------HIKICDFGLARQL-TTFCGTPWYMAPEVL-----------GYGKCKCDWWSC GMIIICMCLNKHKVLEDHLDPEQLLDNLKVKVEQKLYSNDLFLLLKDMVDEDPEKRPSYKDVQE------KLKII | |.. |. . .......... | .. ... . . ||||||. .. . . . GCILYEMLCGYPPFP----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 29028.AA | Ciliate-E1 | 29-203 | 16 | 1.4e-07 | 21.28 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 29-203 Range on HMM: 1-202/202 Sequence Identity: 16% (34 aa) IAEGRLGRVYSYIKKKTG-EAFAVQIMQNLDRQT----------RFNVMEEIR-TIYS-EIHTRKGGQLETYSLHLIMEIGYSLLHIMK----------- |..| ..|. ..... . |..| . . .. ...|. .. .|. .| . .. .. .... .||. .. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC --QQPDMSMKDILYHFKNIIKIIVKLHSNKLYHGNLKPQNILYIEEKNSIGGKTKKLKFSGFFNTKKGQKT-YTPYTPKDLVSQWKN---YDRINGNYLL .| ... . ... ....|. . ||.....|...||||||. ..| . .. | |.. .. | . |. || . .. .| . | |. QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC---DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKI --LGDIY ||| NYKSDIY |
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Kinase | 29028.AA | TKL | 201-271 | 18 | 6.7e-07 | 20.89 | In-house | 271-364 (364) | Show / Hide |
Range on Protein: 201-271 Range on HMM: 271-364/364 Sequence Identity: 18% (17 aa) DIYSIGMIIICMCLNKHKVLEDHLDPEQLL----DNLKVKVEQKL-------------------YSNDLFLLLKDMVDEDPEKRPSYKDVQEKL |.|| |... .. .. ... .|... . ... .. .| .. |..| |.||||||| ... ..| DVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | 29028.AA | NAK-Unclassified | 242-273 | 40 | 1.1e-05 | 15.46 | In-house | 374-405 (405) | Show / Hide |
Range on Protein: 242-273 Range on HMM: 374-405/405 Sequence Identity: 40% (13 aa) YSNDLFLLLKDMVDEDPEKRPSYKDVQEKLKI |||.| | |.|. ||| ||. | ... . YSNQLHNLIKIMLNEDPIQRPNIYQVLNHICQ |
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Kinase | 29028.AA | NAK | 242-271 | 36 | 1.2e-05 | 14.78 | In-house | 270-299 (299) | Show / Hide |
Range on Protein: 242-271 Range on HMM: 270-299/299 Sequence Identity: 36% (11 aa) YSNDLFLLLKDMVDEDPEKRPSYKDVQEKL ||... | ..| ..|||.||. .| ..| YSQQMHDLIRYMLTPDPEQRPNIYQVLNQL |
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Kinase | 29028.AA | Ciliate-E2b | 96-144 | 21 | 1.6e-05 | 12.96 | In-house | 84-134 (272) | Show / Hide |
Range on Protein: 96-144 Range on HMM: 84-134/272 Sequence Identity: 21% (11 aa) GYSLLHIMKQQP--DMSMKDILYHFKNIIKIIVKLHSNKLYHGNLKPQNIL | .|. .. .. .| .| . .. |.... ||... .. .|| ||. GMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIM |
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Kinase | 29028.AA | TKL-ciliate1 | 240-271 | 18 | 4.3e-05 | 13.38 | In-house | 248-279 (279) | Show / Hide |
Range on Protein: 240-271 Range on HMM: 248-279/279 Sequence Identity: 18% (6 aa) KLYSNDLFLLLKDMVDEDPEKRPSYKDVQEKL . .. . |.... ...| |||. . . | FDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL |
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Kinase | 29028.AA | RGC | 255-273 | 40 | 6.4e-05 | 13.48 | In-house | 281-300 (300) | Show / Hide |
Range on Protein: 255-273 Range on HMM: 281-300/300 Sequence Identity: 40% (8 aa) DEDPEKRPS-YKDVQEKLKI .||||.||. . ....|| AEDPEERPDMFDQIRKQLKT |
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Kinase | 29028.AA | RGC | 255-273 | 40 | 6.9e-05 | 13.48 | In-house | 281-300 (300) | Show / Hide |
Range on Protein: 255-273 Range on HMM: 281-300/300 Sequence Identity: 40% (8 aa) DEDPEKRPS-YKDVQEKLKI .||||.||. . ....|| AEDPEERPDMFDQIRKQLKT |
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Kinase | 29028.AA | Ciliate-A5 | 128-144 | 47 | 0.000103 | 12.37 | In-house | 115-131 (275) | Show / Hide |
Range on Protein: 128-144 Range on HMM: 115-131/275 Sequence Identity: 47% (8 aa) LHSNKLYHGNLKPQNIL |..|...||...||||. LQQNNICHGDIRPQNIC |
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Kinase | 29028.AA | Ciliate-E3 | 118-144 | 33 | 0.000561 | 8.63 | In-house | 109-135 (202) | Show / Hide |
Range on Protein: 118-144 Range on HMM: 109-135/202 Sequence Identity: 33% (9 aa) FKNIIKIIVKLHSNKLYHGNLKPQNIL ...||. . .|. .. |. .||.||| CIQIIQGMIAIHEKNIIHSDIKPDNIL |
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Kinase | 29028.AA | Ciliate-A5 | 200-271 | 24 | 0.00061 | 9.66 | In-house | 199-275 (275) | Show / Hide |
Range on Protein: 200-271 Range on HMM: 199-275/275 Sequence Identity: 24% (19 aa) GDIYSIGMIIICMCLNKHK---VLEDHL---DPEQLLDNLKVKVEQKLYSNDLFLLLKDMVDEDPEKRPSYKDVQEKL .|....|||. ||. .... . .||.. | ..|.| ||. . ..| | ...|||. . .. | SDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKK-YSEQFINFIKQMLQFEENKRPDFHQIYQYL |
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Kinase | 29028.AA | TKL-ciliate1 | 128-148 | 52 | 0.007902 | 5.51 | In-house | 119-141 (279) | Show / Hide |
Range on Protein: 128-148 Range on HMM: 119-141/279 Sequence Identity: 52% (12 aa) LHSNK--LYHGNLKPQNILYIEE ||... | | .|| ||||| |. LHMRQNPLIHRDLKMQNILYDEP |
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Kinase | 29028.AA | Ciliate-E3 | 201-213 | 38 | 0.016319 | 4.0 | In-house | 190-202 (202) | Show / Hide |
Range on Protein: 201-213 Range on HMM: 190-202/202 Sequence Identity: 38% (5 aa) DIYSIGMIIICMC |.||.| ... .| DYYSVGAVFCQLC |
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Kinase | 29028.AA | TKL | 128-144 | 36 | 0.025732 | 4.16 | In-house | 148-172 (364) | Show / Hide |
Range on Protein: 128-144 Range on HMM: 148-172/364 Sequence Identity: 36% (9 aa) LHSNK--------LYHGNLKPQNIL |||.. . | .||..||| LHSMNPKWCTKPPIIHRDLKSKNIL |
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Kinase | 29028.AA | RGC | 129-142 | 64 | 0.207125 | 1.0 | In-house | 103-116 (300) | Show / Hide |
Range on Protein: 129-142 Range on HMM: 103-116/300 Sequence Identity: 64% (9 aa) HSNKLYHGNLKPQN || ||||||. | HSPIRYHGNLKSWN |
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Kinase | 29028.AA | RGC | 129-142 | 64 | 0.216043 | 1.0 | In-house | 103-116 (300) | Show / Hide |
Range on Protein: 129-142 Range on HMM: 103-116/300 Sequence Identity: 64% (9 aa) HSNKLYHGNLKPQN || ||||||. | HSPIRYHGNLKSWN |