Gene 2882 (Tetrahymena)
2882
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 2882.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 2882.AA | Ciliate-A5 | 111-291 | 20 | 4.7e-10 | 31.13 | In-house | 71-275 (275) | Show / Hide |
Range on Protein: 111-291 Range on HMM: 71-275/275 Sequence Identity: 20% (43 aa) LIFEYCESSVETEIQHLKKRN--KQLKKSTLRKIFESVAIALNHFHTKQIVHGDLRSSKIFKNEQGQYKLMPPK------I------KNRKATEKYYHSP ...|| . |.|.| |. .. . . | | .. .. .. ..|.|||.| . |. ..||.||| . . ...... .. CYYEYHDNNLEQEMQMRKQCQKDIFYNEQELWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMNESKDFFYQINWSSYKQYQHHMSTENK EYHLSKNFRAAYEK-------QQNNPIKGEIYTFGMIMLELGTFSDD--LYNAYGKFQMNED-VIQNALQNFSMLYGYHLTAVVKKMLNLDAQLRPTAND |. . . . . | |..... |||.||. | | |. | || . .| ..| . |. .... |.||... ||. . QYLSPMQWYQMMHRDEQNIQRPEHNWYKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQ IIELL | ..| IYQYL |
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| Kinase | 2882.AA | Ciliate-B2 | 111-178 | 27 | 5.3e-10 | 19.61 | In-house | 78-145 (197) | Show / Hide |
Range on Protein: 111-178 Range on HMM: 78-145/197 Sequence Identity: 27% (19 aa) LIFEYCESSVETEIQHLKKRNKQLKKSTLRKIFESVAIALNHFHTKQIVHGDLRSSKIFKNEQGQYKL || | || | . |.| ..| |. .. | ... .| |. . |.| |.. . | . ..|.|.. LIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVY |
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| Kinase | 2882.AA | NRBP | 108-292 | 22 | 4.3e-07 | 20.66 | In-house | 73-261 (261) | Show / Hide |
Range on Protein: 108-292 Range on HMM: 73-261/261 Sequence Identity: 22% (43 aa) RYFLIFEYCES-SVETEIQHLKKRNKQLKKSTLRKIFESVAIALNHFHTKQ--IVHGDLRSSKIFKNEQGQYKL---MPPKIKNRKATEKYYHSPEYHLS | | || | |.. ... || .|.... . .. . ||.. |. . |.|| | . || . | |. .| .|... |.. . .... RVIFITEYMSSGSMKQFLKKTKKNHKNMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGCVWPDAIHHHVRTCREEMRNMHFFA KNFRAAYEKQQNNPIKGEIYTFGMIMLELGTFSDDLYNAYGKFQ-MNEDVIQNALQNFSMLYGYHLTAVVKKMLNLDAQLRPTANDII--ELLQ .. .. . .||.||| ||. . . |. . ..|..|| | . | ...| |. | . ||.|.... ..| PEYGILEVTDLTTAV--DIYSFGMCALEMAVLEIQSGCQNGESEYVTEEAIQRAIH---SLEDPMQRDFIRKCLQKDPARRPSARELLFHQILF |
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| Kinase | 2882.AA | CAMK-Unique | 108-163 | 20 | 6.1e-07 | 18.74 | In-house | 109-183 (363) | Show / Hide |
Range on Protein: 108-163 Range on HMM: 109-183/363 Sequence Identity: 20% (15 aa) RYFLIFEYCESS-VETEIQH----------------LKKRNKQLKK--STLRKIFESVAIALNHFHTKQIVHGDL ..... |||. . .||. ||. . .. . . |. ... |... | ..|||.|| YMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDL |
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| Kinase | 2882.AA | NEK6 | 124-178 | 32 | 4e-06 | 15.82 | In-house | 90-144 (252) | Show / Hide |
Range on Protein: 124-178 Range on HMM: 90-144/252 Sequence Identity: 32% (18 aa) IQHLKKRNKQLKKSTLRKIFESVAIALNHFHTKQIVHGDLRSSKIFKNEQGQYKL |.| || . . |. | | .. ||.| | | ..| |.. .| .| || IKHFKKQKRLIPERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKL |
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| Kinase | 2882.AA | Ciliate-A7 | 130-162 | 26 | 5e-06 | 17.8 | In-house | 112-157 (360) | Show / Hide |
Range on Protein: 130-162 Range on HMM: 112-157/360 Sequence Identity: 26% (12 aa) RNKQLKKS------------TLRKIFESVAIALNHFHT-KQIVHGD ..|.|... ..| .| ..| ||.. |. |.|.|.| PHKNLHHNEKIENQCEYCVNQMRHCFRQIAQALHYLHNEKNIAHND |
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| Kinase | 2882.AA | Ciliate-C4 | 126-168 | 25 | 6e-06 | 14.76 | In-house | 125-171 (361) | Show / Hide |
Range on Protein: 126-168 Range on HMM: 125-171/361 Sequence Identity: 25% (12 aa) HLKKRNKQLKK--ST--LRKIFESVAIALNHFHTKQIVHGDLRSSKI ..|| . |.. . ..|. .. || | | . .||.|.....| NFKKLYYHLFQDKNNNLCKKFIQHICHALWHLHQNKWVHCDIKPENI |
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| S_TKc | 2882.AA | S_TKc | 30-296 | 12 | 1.2e-05 | -93.98 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 30-296 Range on HMM: 1-231/231 Sequence Identity: 12% (40 aa) FEFVHLSG-------LKGLERA--RQIQQKSTNKMFDYIEMDLRGVDTIDKYENYCESLFEINQKEILQMK-------FYSRVFVEESLGDPYCRYFLIF .|.. . | |. .. |. | . | ..|| .| . ||.. ...... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------EHIRREIQILKKHHPNIVKLYDVFQD-------DHLYMVM EYCES---SVETEIQHLKKRNKQ--LKKSTLRKIFESVAIALNHFHTKQIVHGDLR----------------SSKIFKNEQGQYKLMPPKIKNRKATEKY |||. .. . |.. ... .. . . |... .. ||.. | ..|.| || ..... . | . EYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------------TTFCGT-PW YHSPEYHLSKNFRAAYEKQQNNPIKGEIYTFGMIMLELGT----FSDDLYNAYGKFQMNEDVIQNALQNFSMLYGYHLTAVVKKMLNLDAQLRPTANDII | .|| . .. | .. .| |. |. . |. ... . | . ..|.|. | . |||| .. YMAPEVL------------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EAL E----LLQSQEL . . . . QDEWDIKCHPWF |
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| Kinase | 2882.AA | PEK | 114-169 | 17 | 4e-05 | 12.95 | In-house | 363-459 (655) | Show / Hide |
Range on Protein: 114-169 Range on HMM: 363-459/655 Sequence Identity: 17% (17 aa) EYCE-SSVETEIQHLK-----------------------------------KRN-----KQLKKSTLRKIFESVAIALNHFHTKQIVHGDLRSSKIF |||| .. .. |.. . . . ... | ....||. .. .||. | ....| ||. | || EYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIF |
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| Kinase | 2882.AA | SgK495 | 267-291 | 40 | 5.2e-05 | 11.73 | In-house | 147-171 (171) | Show / Hide |
Range on Protein: 267-291 Range on HMM: 147-171/171 Sequence Identity: 40% (10 aa) TAVVKKMLNLDAQLRPTANDIIELL .....|.| ||.| | || ..|| . VCLIRKLLVLDPQQRLTATQVIEAV |
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| Kinase | 2882.AA | WEE | 108-163 | 23 | 0.00012 | 11.59 | In-house | 79-138 (297) | Show / Hide |
Range on Protein: 108-163 Range on HMM: 79-138/297 Sequence Identity: 23% (14 aa) RYFLIFEYCESS---VETEIQHLKKRNKQLKKSTLRKIFESVAIALNHFHTK-QIVHGDL .... |||... ||. .. |. | . ...|. .. .|.| | . .|| |. HMYIQMEYCNGGSNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDI |
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| Kinase | 2882.AA | SgK495 | 123-164 | 33 | 0.003537 | 5.97 | In-house | 1-42 (171) | Show / Hide |
Range on Protein: 123-164 Range on HMM: 1-42/171 Sequence Identity: 33% (14 aa) EIQHLKKRNKQLKKSTLRKIFESVAIALNHFHTKQIVHGDLR .|| . |.| || | | | ||| ||. NLQHHVIHEKRLSERETVYIFHDVVRIVEALHQKNIVHRDLK |
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| Kinase | 2882.AA | WEE | 266-296 | 35 | 0.003844 | 6.47 | In-house | 270-297 (297) | Show / Hide |
Range on Protein: 266-296 Range on HMM: 270-297/297 Sequence Identity: 35% (11 aa) LTAVVKKMLNLDAQLRPTANDIIELLQSQEL |. ..| |.. | ..|||.. .|||. .| LKQLIKWMMHPDPEQRPTCQ---QLLQHPVL |
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| Kinase | 2882.AA | PEK | 270-296 | 33 | 0.029984 | 2.76 | In-house | 632-655 (655) | Show / Hide |
Range on Protein: 270-296 Range on HMM: 632-655/655 Sequence Identity: 33% (9 aa) VKKMLNLDAQLRPTANDIIELLQSQEL ...||..| | ||.| ..||. . IQWMLSHDPQQRPSA---QQILQHEFF |
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| MORN | 2882.AA | MORN | 545-567 | 60 | 1.3e-07 | 32.36 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 545-567 Range on HMM: 1-23/23 Sequence Identity: 60% (14 aa) YEGEFLNGKYHGIGIYYWPTGVK ||||. ||| || |.|.||.| . YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 2882.AA | MORN | 543-564 | 54 | 7.3e-07 | 30.04 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 543-564 Range on HMM: 1-22/22 Sequence Identity: 54% (12 aa) EIYEGEFLNGKYHGIGIYYWPT .||||. ||| || |.|.|. DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 2882.AA | MORN | 589-610 | 54 | 4e-06 | 27.5 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 589-610 Range on HMM: 1-22/22 Sequence Identity: 54% (12 aa) DIYFGEWHRGKNHGKGTFYWQK |.| ||||.|| ||.|...| DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 2882.AA | MORN | 522-544 | 39 | 0.000176 | 21.03 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 522-544 Range on HMM: 1-23/23 Sequence Identity: 39% (9 aa) YQGEKLQGVPHGWGIFWWANGEI |.|| .|..|| |...|..| YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 2882.AA | MORN | 520-541 | 54 | 0.000604 | 18.46 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 520-541 Range on HMM: 1-22/22 Sequence Identity: 54% (12 aa) HRYQGEKLQGVPHGWGIFWWAN ||.|| | .|| |..|||| DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 2882.AA | MORN | 591-608 | 55 | 0.006208 | 15.41 | Pfam | 1-18 (23) | Show / Hide |
Range on Protein: 591-608 Range on HMM: 1-18/23 Sequence Identity: 55% (10 aa) YFGEWHRGKNHGKGTFYW | |||..|| ||.|...| YEGEWKNGKMHGHGVYTW |
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| MORN | 2882.AA | MORN | 568-590 | 34 | 0.896683 | 7.57 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 568-590 Range on HMM: 1-23/23 Sequence Identity: 34% (8 aa) HYGEFSYGEIKGLGVRFYQEGDI ||.. | . | || . || YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 2882.AA | MORN | 615-633 | 26 | 14.884387 | 3.14 | Pfam | 1-19 (23) | Show / Hide |
Range on Protein: 615-633 Range on HMM: 1-19/23 Sequence Identity: 26% (5 aa) FKGNFLKDKIYGKGTLILP . |.. ..|. |.|... | YEGEWKNGKMHGHGVYTWP |
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| MORN | 2882.AA | MORN | 670-676 | 71 | 62.687629 | 0.87 | Pfam | 1-7 (23) | Show / Hide |
Range on Protein: 670-676 Range on HMM: 1-7/23 Sequence Identity: 71% (5 aa) YEGLWKD ||| ||. YEGEWKN |
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