Gene 27698 (Tetrahymena)
27698
Sequence
Protein domains of 27698.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 27698.AA | C2 | 48-147 | 45 | 3.1e-51 | 173.27 | In-house | 1-102 (245) | Show / Hide |
Range on Protein: 48-147 Range on HMM: 1-102/245 Sequence Identity: 45% (46 aa) GSFAIVLKALNKITGQTVALKVVECDESDFKAMEVIQNEYKMLEVFSGCKYIIKVFNSFYLTESNDSDEDEDDDQIPVGQNN--NQSNLIRVFYVMEQEL |.|..|||| || ....||||..||...|.. |. .|.||.... .....|||||.|.||||.....|||||.|.....|.| .|.|. ..|.|.||| GAFGLVLKAFNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQEF CQ || CQ |
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Kinase | 27698.AA | Ciliate-C8 | 48-150 | 35 | 8e-32 | 111.37 | In-house | 1-100 (238) | Show / Hide |
Range on Protein: 48-150 Range on HMM: 1-100/238 Sequence Identity: 35% (38 aa) GSFAIVLKALNKITGQTVALKVVEC-DESDFKAMEVIQNEYKMLEVFSGCKYIIKVFNSFYLTESNDSDEDEDDDQIPVGQNN--NQSNLIRVFYVMEQE |.|..|||| || ....||||..|| .. . . || .. ||.|. |. ......|...|||.| |....|...|.|...|.. . .|.|||.| GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKK------SFFVMEME LCQNDC .||. | KCQQNC |
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Kinase | 27698.AA | CMGC | 39-107 | 16 | 5.2e-14 | 41.51 | In-house | 1-108 (513) | Show / Hide |
Range on Protein: 39-107 Range on HMM: 1-108/513 Sequence Identity: 16% (18 aa) YQILQFAGNGSFAIVLKALNKITG--------------QTVALKVVECDESDFKAME----------VIQNEYKMLEVFS----------------GCKY |.|.. | |....| |. .| |. . ||.| . .. . . .. | |.|. .. .. YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN IIKVFNSFY |.| ...|| IVKLYDIFY |
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Kinase | 27698.AA | STE20 | 39-107 | 29 | 7e-13 | 43.69 | In-house | 1-74 (288) | Show / Hide |
Range on Protein: 39-107 Range on HMM: 1-74/288 Sequence Identity: 29% (22 aa) YQILQFAGNGSFAIVLKALNKITGQT----VALKVVECDESDF--KAMEVIQNEYKMLEVFSGCKYIIKVFNSFY |..|. |.||. | || .| ||. || |... .. | . .| ||.|. .. . ...|.| ..|.. YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYL |
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Kinase | 27698.AA | STE | 39-107 | 17 | 2.2e-11 | 36.61 | In-house | 1-100 (359) | Show / Hide |
Range on Protein: 39-107 Range on HMM: 1-100/359 Sequence Identity: 17% (17 aa) YQILQFAGNGSFAIVLKALNKI---------------TGQTVALKVVECDESDF---------------KAMEVIQNEYKMLEVFSG-CKYIIKVFNSFY ...... |.|.| | ||.|. ||. .| |... .... . |. |..| |.. .. ...|.| . ... WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF |
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Kinase | 27698.AA | CDK | 39-70 | 40 | 9.4e-11 | 30.46 | In-house | 1-37 (284) | Show / Hide |
Range on Protein: 39-70 Range on HMM: 1-37/284 Sequence Identity: 40% (15 aa) YQILQFAGNGSFAIVLKALNKITG-----QTVALKVV |..|. | |....| || .|.|| | |||| . YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKI |
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Kinase | 27698.AA | C8 | 36-148 | 26 | 1.2e-10 | 33.32 | In-house | 1-104 (226) | Show / Hide |
Range on Protein: 36-148 Range on HMM: 1-104/226 Sequence Identity: 26% (30 aa) QKHYQILQFAGNGSFAIVLKALNKITGQTVALKVVEC-DESDFKAMEVIQNEYKMLEVFSGCKYIIKVFNSFYLTESNDSDEDEDDDQIPVGQNNNQSNL . .|.| | |....|||| | ....||. .| ...| . .| |. ||.|..||. . .. . . ||. ... |... ..| . .. FNNFQYLSF---GAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEE------ IRVFYVMEQELCQN . . ||| |||.. -KSCFVMEMELCEQ |
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Kinase | 27698.AA | CDK7 | 39-68 | 46 | 4.2e-10 | 22.66 | In-house | 1-30 (288) | Show / Hide |
Range on Protein: 39-68 Range on HMM: 1-30/288 Sequence Identity: 46% (14 aa) YQILQFAGNGSFAIVLKALNKITGQTVALK |..... | | || | ||. . ||| || | YEKIKHIGEGQFATVYKACDHQTGQIVAIK |
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Kinase | 27698.AA | MST | 39-81 | 34 | 1.1e-09 | 26.84 | In-house | 1-42 (254) | Show / Hide |
Range on Protein: 39-81 Range on HMM: 1-42/254 Sequence Identity: 34% (15 aa) YQILQFAGNGSFAIVLKALNKITGQTVALKVVECDESDFKAME . |. | ||. | ||..| ||. || |.| ..|. ... FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV-NEDLQEII |
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Kinase | 27698.AA | MARK | 39-86 | 36 | 2.9e-09 | 26.63 | In-house | 1-49 (262) | Show / Hide |
Range on Protein: 39-86 Range on HMM: 1-49/262 Sequence Identity: 36% (18 aa) YQILQFAGNGSFAIVLKALNKITGQTVALKVVE-CDESDFKAMEVIQNE | .|. | ||.| | .|..| ||. ||.|..| . .|...|. .. | YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMRE |
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Kinase | 27698.AA | Pkinase | 39-107 | 23 | 1.3e-08 | 31.54 | Pfam | 1-70 (293) | Show / Hide |
Range on Protein: 39-107 Range on HMM: 1-70/293 Sequence Identity: 23% (17 aa) YQILQFAGNGSFAIVLKALNKITGQTVALKVVECDESDFKAMEVIQN--EYKMLEVFSGCKYIIKVFNSFY |.|.. | |||. | |. .| ||..||.|... .. . . . . | ... . ....|.. . .|. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFE |