Gene 26940 (Tetrahymena)
26940
Sequence
Protein domains of 26940.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 26940.AA | CDK | 1-292 | 36 | 1.3e-118 | 381.21 | In-house | 7-284 (284) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-284/284 Sequence Identity: 36% (120 aa) LGEGTFGKVYKAQDKKNN-----EIVAVKQVKTQN-YHESRNDFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQN---------QNSIFLIFEYCQMD .||||.|.||||.||... .||| |.....| ... . . . . ||.|| || |||||. ..|... | .|.....|||. .| IGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEG-REEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHD IANLIFRMDQEREYFSESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGV-----VKIADFGLAREYNK------PNKPYTPKVVTLWYRSPEL . .. |||...|||.|. ..|.. ||||.| .| |||..|. .|||||||||... ||..||..|||||||.||| LKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL LLEMEQYT--TSIDIWSVGCVLAELLN--KGQPIFPGDTEMKQFQLICELIGYPTRYEWN-----EYYSQVKKEVRKELEKFSGFKTNNLQKQLKCSENC || ..|. |.||.|||||..||... ..|.||||.| | .|....| || | .| LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------------- LKLLQKMLAWDPKKRISAEKAMSHPYF ||.|||. ||||||||| |..|||| -DLLNKMLCYDPKKRISAEQALQHPYF |
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Kinase | 26940.AA | CMGC | 1-292 | 23 | 1.3e-116 | 384.97 | In-house | 7-513 (513) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-513/513 Sequence Identity: 23% (121 aa) LGEGTFGKVYKAQD--------------KKNNEIVAVKQVK-TQNYHESRN----DFKIYFIQLKEIKLLSELQ----------------NHPNIVQFKE .||||.|.|||..| ...|||||.| .| . |.| . .. | |||.| .|. .|.|||. .. IGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYD VVVGQN---------------QNSIFLIFEYCQMDIANLIFRMDQ-----EREYFSESE------------IKCII------LQLLNGVQ--HMHKQY-- ... | |...|.|||...| ...| .. . . ..|| . ||... |.|.|. ..|.. IFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGN QMHRDIKLSNVLINDK--------------------GVVKIADFGLAREYNKP---------------------NKPYTPKVVTLWYRSPELLLEMEQYT .|||.| .|.|||.. |..||.|||||| |... |.|||. |||.|||.||.|| ...|| IIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYT ---------TSIDIWSVGCVLAELLNK-------GQPIFPGDTE-----------MKQFQLICELIGYPT---------------RYEWNEYYS------ |.||.|||||..||.... |.|.|||..| | ..|....| || || .. . NHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNK ------------QVKKEVRKELEK---FSGFKTNNLQKQLK------------------------------------CSENCLKLLQKMLAWDPKKRISA . .. .|. ... | .. ...... . |.. .. ||.||| .||.|||.| FPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITA EKAMSHPYF | |..|||| EQALQHPYF |
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Kinase | 26940.AA | PITSLRE | 45-292 | 44 | 3.7e-102 | 345.7 | In-house | 48-295 (295) | Show / Hide |
Range on Protein: 45-292 Range on HMM: 48-295/295 Sequence Identity: 44% (113 aa) LKEIK-LLSELQNHPNIVQFKEVVVGQNQNSIFLIFEYCQMDIANLIFRMDQEREYFSESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVVK | ||. .| .|| |||||. ||.|.| | ..|....|| |.. |. | . . |...|||| ..|||.||.|||. |||| | || |.. ||. | LREINMILMALQ-HPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILK IADFGLAREYNKPNKPYTPKVVTLWYRSPELLLEMEQYTTSIDIWSVGCVLAELLNKGQPIFPGDTEMKQFQLICELIGYPTRYEWNEYYSQVKKEVRKE |.|||||||| | ||||| |||||||.|||||. . |.| .|.|||||..||.. . .|.|.|. |. | . | . | || | . . . | ICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITM-KPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTEL---PHWKM LEKFSGFKTNNLQKQLK----CSENCLKLLQKMLAWDPKKRISAEKAMSHPYF .. |. . ||| | . |.. ..||..|| .||.||.|..|. ||.| MNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF |
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Kinase | 26940.AA | CDC2 | 1-292 | 36 | 2.4e-101 | 312.25 | In-house | 7-301 (301) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-301/301 Sequence Identity: 36% (112 aa) LGEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRNDFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQNQNSIFLIFEYCQMDIANLIFRMDQEREYF .||||.|.|||..|.. |.|||.|.... .|. | . ..|| .| ||..|||||. ..|.. |.....|||. || .. . . .... IGEGTYGVVYKCKDMQTNQIVALKKIRLE--QEDEGD-GVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKNKHM SESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVVKIADFGLAREYNKPNKPYTPK--VVTLWYRSPELLLEMEQYTTSIDIWSVGCVLAEL- ... .| .. |.|.|| . | . ||||.| .| ||..||..||||||||| . | ..||. |||||||.||.|| ..|.|..|.||.||..||. PPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMF LN-KGQPIFPGDTEMKQFQLICELIGYPTRYEWNEYYSQV--KKEVRKELEKFSGFKTNNLQKQLK----------CSENCLKLLQKMLAWDPKKRISAE .. |.|.|| | | | . .| |. .|.. .. | ..| .|...|.|... . .... ||..||. || |||||. MDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYK-------NTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAK KAMSHPYF .|..|||| EALQHPYF |
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Kinase | 26940.AA | CDK7 | 1-292 | 34 | 2.4e-97 | 259.78 | In-house | 7-288 (288) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-288/288 Sequence Identity: 34% (103 aa) LGEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRNDFK--IYFIQLKEIKLLSELQNHPNIVQFKEVVVGQNQNSIFLIFEYCQMDIANLIFRMDQERE .|||.|. ||||.|.. ..|||.| .| .|...| | . . |||.| |.| |.|.. . . .| |.|.. . | | |.. IGEGQFATVYKACDHQTGQIVAIKKIKK---LGHRSEAKDGINRTAIREIKILQEMQ-HDNVIGLIDIFM--HKSNIQLVFDFMDWDLEVVI--KDKSI- YFSESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVVKIADFGLAREYNKPNKPYTPKVVTLWYRSPELLLEMEQYTTSIDIWSVGCVLAELL . ..|| . ...| |. ..|. . |||.| | |.| |..||||||||| | ||. ||..||| |||.|||| .|.|..|.|||||..|||. ILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELM NKGQPIFPGDTEMKQFQLICELIGYPTRYEWNEYYSQVKKEVRKELEKFSGFKTNNLQKQLK-CSENCLKLLQKMLAWDPKKRISAEKAMSHPYF |..||| .. | . |.. .| || || . .. . . .. .| |. |.. |. | |...|.. .| ||... . ..||| LR-VPYLPGDSDIDQLTRIFQTLGTPTEEEWPN-MCCMMDYI--KFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF |
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Kinase | 26940.AA | CDK10 | 1-292 | 43 | 3.8e-91 | 309.12 | In-house | 7-285 (285) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-285/285 Sequence Identity: 43% (126 aa) LGEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRNDFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQNQNSIFLIFEYCQMDIANLIFRMDQEREYF .||||.| ||.| | . .||||.|.|. . . . |.||.|| ... |.|||. .|||||| .||||. .|| |.| |. | | | VGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDG-----LPISGLREIMLLIQCR-HENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQP---F SESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVVKIADFGLAREYNKPNKPYTPKVVTLWYRSPELLLEMEQYTTSIDIWSVGCVLAELLNK .|...|||.||.| |.. .|... .|||.| ||.|. ||| .|.||||||| | | || |||.|||||| ||||| . ||.||.| |||.|.||| TETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELL-V GQPIFPGDTEMKQFQLICELIGYPTRYEWNEYYSQVKKEVRKELEKFSGFKTNNLQKQLKC-SENCLKLLQKMLAWDPKKRISAEKAMSHPYF ..|..|| |..| ..| .|.| | | .|.. . |.| |||... . |. ..||. .. ..|||| || .. || HKPLMPGNSEIHQIDMIIDLLGTPSENIWPG-FSDLPMVQNFTLKKQP---YNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF |
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Kinase | 26940.AA | S_TKc | 1-292 | 27 | 3.1e-89 | 303.66 | SMART | 7-231 (231) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-231/231 Sequence Identity: 27% (83 aa) LGEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRNDFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQNQNSIFLIFEYCQM---DIANLIFRMDQER .|.|.||||||...|| ..|||.|..| ..||..|.. .|||||....| . .......||| | .| .. .. IGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG --EYFSESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVVKIADFGLAREYNKPNKPYTPKVVTLWYRSPELLLEMEQYTT-SIDIWSVGCVL .|.| ...... |........|.. .|||.| .|.|... ..||.||||||.. | ..|.||..||.| .|.. ..|.||.||.| LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL AELLNKGQPIFPGDTEMKQFQLICELIGYPTRYEWNEYYSQVKKEVRKELEKFSGFKTNNLQKQLKCSENCLKLLQKMLAWDPKKRISAEKAMS------ .|.| |.| || | |.. ..|| |. .. ...|.| .||.||..| .|. YEMLC-GYPPFP------QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK -HPYF ||.| CHPWF |
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Kinase | 26940.AA | CRK7 | 2-292 | 37 | 7.7e-89 | 301.46 | In-house | 8-343 (343) | Show / Hide |
Range on Protein: 2-292 Range on HMM: 8-343/343 Sequence Identity: 37% (131 aa) GEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRNDFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQ-------NQN-SIFLIFEYCQMDIANLIFRM ||||.|.||||..|...|.|| | |...| . | | | |||.| .| ||.|||. ||.|. .. |....||| | . | GEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAI--REIKILRQL-NHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGLL--E DQEREYFSESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVVKIADFGLAREYNKPN--KPYTPKVVTLWYRSPELLLEMEQY---------- | .||....||. ||| |.. .||. .||||| ||.|.| .| |||||||||| ||. . .||| .|.||||| ||||| |.| SKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELI ----------------------------TTSIDIWSVGCVLAELLNKGQPIFPGDTEMKQFQLICELIGYPTRYEWNE-----YYSQVKKEV---RKELE ...||.||.|| |.||..| .|||.| ||.| .| .. | |. | | .. | |. .| RNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTK-KPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLRE KFS-GFKTNNLQKQLKCSENCLKLLQKMLAWDPKKRISAEKAMSHPYF |. .| .. |. || || |||. |||||..|| . |..| EFYHHKKPVFMPKE------CLDLLDKMLCLDPKKRFTAEECLQHDWF |
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Kinase | 26940.AA | Pkinase | 1-292 | 30 | 2.3e-87 | 301.33 | Pfam | 7-293 (293) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-293/293 Sequence Identity: 30% (96 aa) LGEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRN--DFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQNQNSIFLIFEYCQM-----DIANLIFRM .|.|.||.|||...|....|||||..| .. ... . .... ||... .| ||||||...... ..| ...|||.. | . .| . IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----SEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST- DQEREYF--SESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVV----KIADFGLAREY-NKPNKPYTPKVVTLWYRSPELLLEMEQYTTSID ... | || |.|....|.| |....|.. .|||.|..|.||...|.. ||.|||||. . . .| .| ..|.||..||.... . |....| -WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD IWSVGCVLAELLNKGQPIFPGD----TEMKQFQLICELIGYPTRYEWNEYYS--------QVKKEVRKELEKFSGFKTNNLQKQLKCSENCLKLLQKMLA .||.||.|.|.|. |.|.|||. . . | |.||. | |....| . .| . . . . . . ||.|.... ..|. MWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHW-H--------------F-HWTF-HNWSEECKDFIKWCLC WDPKKRISAEKAMSHPYF .|||||..|| .. ||.| KDPKKRPTAEQILQHPWF |
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Kinase | 26940.AA | RCK | 1-292 | 38 | 6.3e-84 | 266.15 | In-house | 7-298 (298) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-298/298 Sequence Identity: 38% (117 aa) LGEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRNDFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQNQNSIFLIFEYCQMDIANLIFRMDQEREY- ||.||.| | |||.|...|||| |. | . .| .. ..|.||| | | ||||.. |||. .. . ...|||..|.. .. . |. LGDGTYGCVMKAQNKETGEIVAIKKMK--QKFYSWEE----CMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKE-RRKY FSESE--IKCIILQLLNGVQHMHKQYQMHRDIKLSNVLIND---------KGVVKIADFGLARE-YNKPNKPYTPKVVTLWYRSPELLLEMEQYTTSIDI ..|.. || |. |.| | ||||. .|||.| | .... ...|||||||.|| ..|| ||| | | |||.||.|| .|.. .|| LPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKP--PYTDYVSTRWYRAPECLLRCTYYNSPMDI WSVGCVLAELLNKGQPIFPGDTEMKQFQLICELIGYPTRYEWNEYYSQVKKEVRKELEKFSGFKTNNLQKQL-KCSENCLKLLQKMLAWDPKKRISAEKA |.|||. .|| . .| ||| |. | . ||. .| |. .|.. | .. . ... .| | ..|.. . || .|..|..|||.|||.|||.|..| WAVGCIMYELYML-RPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQ---MNF-NFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQA MSHPYF |||| LQHPYF |
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Kinase | 26940.AA | CDK5 | 1-292 | 37 | 1.7e-80 | 254.01 | In-house | 7-287 (287) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-287/287 Sequence Identity: 37% (110 aa) LGEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRNDFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQNQNSIFLIFEYCQMDIANLIFRMDQEREYF .||||.| ||||..|. |||| |.|. . | . . || || ||. |.||| |. . . |.||.| |. ||. .. IGEGTYGTVYKARNKETHEIVALKRVRLDSEDEG-----VPSTAIREICLLKELK-HKNIVRLHDVIHSEKK--LTLVFEFCDQDLKKY---MDSCNGEM SESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVVKIADFGLAREYNKPNKPYTPKVVTLWYRSPELLLEMEQYTTSIDIWSVGCVLAELLNK . || ...||| |.. |.. .||| | | ||| .| | ||||||| . | . |. ||||||| | |. .|.||||.||.||..||. | DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA GQPIFPGDTEMKQFQLICELIGYPTRYEWNEYYSQVKKE-VRKELEKFSGFK-TNNLQKQLKCSENCLKLLQKMLAWDPKKRISAEKAMSHPYF |.| ||| . | .| ...| |. .| . ...... . . .. ..| .|. . |||||| .|..||||..|. |||| GRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKL--DEKGMDLLQKMLQCNPNQRISAKAALHHPYF |
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Kinase | 26940.AA | MAPK | 47-292 | 30 | 7.9e-73 | 248.27 | In-house | 54-328 (328) | Show / Hide |
Range on Protein: 47-292 Range on HMM: 54-328/328 Sequence Identity: 30% (85 aa) EIKLLSELQNHPNIVQFKEVVVG-----QNQ----NSIFLIFEYCQMDIANLIFRMDQEREYFSESEIKCIILQLLNG--VQHMHKQYQMHRDIKLSNVL ||||| .. .|.||. ... || | | ...|... | ..| ... |. |. .. |.|.| ....| |||.| ||.| EIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQ----PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNIL INDKGVVKIADFGLAREYNK-PNKPY-------------TPKVVTLWYRSPELLLE--MEQYTTSIDIWSVGCVLAELLNKGQPIFPGDTEMKQFQLICE .| . .||.|||||| .... |. |.| |||.||..| . ||...|.||||| .||.|. ..|.|||. . |..|| | VNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIME LIGYPTRYEWNEYYSQVKKEVRKELEKF--SGFKTN-NLQKQLK-----CSENCLKLLQKMLAWDPKKRISAEKAMSHPYF ..| |.. .. ...|. .. . .. ...| .. .. .. ||.|||..||.|||..| |..|||| VLGTPSEEFIQCICM--SEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF |
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Kinase | 26940.AA | TyrKc | 1-292 | 23 | 1.1e-15 | 30.9 | SMART | 7-280 (280) | Show / Hide |
Range on Protein: 1-292 Range on HMM: 7-280/280 Sequence Identity: 23% (75 aa) LGEGTFGKVYKAQDKKNNEIVAVKQVKTQNYHESRNDFKIYFIQLKEIKLLSEL-QNHPNIVQFKEVVVGQ-----NQNSIFLIFEYCQMDIANLIFRMD |||| ||.|||.. | . |||| .| | || ..|......| .|||||.. |.. | .....||. . . . . LGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDF------MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLRK QEREYFSESEIKCIILQLLNGVQHMHKQYQMHRDIKLSNVLINDKGVVKIADFGLAREYNKP-----NKPYTPK----VVT--LWYR--SPELLLEMEQY ... .. .. . .| .| .. |.. |||. |.|......|||.||||.|. .| | | | .| .|| . . . . HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-F TTSIDIWSVGCVLAELLNKGQPIFPGDTE-MKQFQLICELIGYPTRYEWNEYY---SQVKKEVRKELEKFSGFKTNNLQKQLKCSENCLKLLQKMLAWDP || |.|| | .. |.. ||. ||... |. | . |.. | . ... | | |.. .. .. . || TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------F--------VCCPDEMYQIMKQCWHEDP KKRISAEKAMSHPYF ..| . . | .| EDRPTFSEI--HECF |
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Kinase | 26940.AA | Pkinase_Tyr | 1-83 | 32 | 6.3e-12 | 41.02 | Pfam | 7-90 (270) | Show / Hide |
Range on Protein: 1-83 Range on HMM: 7-90/270 Sequence Identity: 32% (30 aa) LGEGTFGKVYKAQDK----KNNEIVAVKQVKTQNYHES---RNDFKIYFIQLKEIKLLSELQNHPNIVQFKEVVVGQNQN-SIFLIFEYCQ |||| ||.|||. | ... |||| . ...... | || ..|.|....| .|||||.. |.. | . .|....||.. LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDF------MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMP |
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Kinase | 26940.AA | PITSLRE | 2-27 | 57 | 9.6e-09 | 28.17 | In-house | 8-33 (295) | Show / Hide |
Range on Protein: 2-27 Range on HMM: 8-33/295 Sequence Identity: 57% (15 aa) GEGTFGKVYKAQDKKNNEIVAVKQVK .|||.| ||.|.||. .|||| | .| HEGTYGVVYRAKDKRTDEIVALKRLK |
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Kinase | 26940.AA | Pkinase_Tyr | 133-202 | 32 | 1.3e-07 | 26.39 | Pfam | 141-212 (270) | Show / Hide |
Range on Protein: 133-202 Range on HMM: 141-212/270 Sequence Identity: 32% (25 aa) NVLINDKGVVKIADFGLAREYNKPNKPYTPKVVTL-------WYRSPELLLEMEQYTTSIDIWSVGCVLAELLNKGQ |.|.....||||.|||||| |. | ... |. .|| . ... .|| |.|| | .. |.. |. NCLVTENNVVKICDFGLARDI--YNDDYY-YRKRGGGKLPIKWM-APECINYGK-FTTKSDVWSFGVLMWEIFTYGE |
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Kinase | 26940.AA | MAPK | 1-24 | 33 | 0.000296 | 10.36 | In-house | 7-36 (328) | Show / Hide |
Range on Protein: 1-24 Range on HMM: 7-36/328 Sequence Identity: 33% (10 aa) LGEGTFGKVYKAQDKK------NNEIVAVK .|.| .| | .| ||. ....||.| IGQGAYGVVCSAIDKRTNQKTKCGKKVAIK |