Gene 26359 (Tetrahymena)
26359
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 26359.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 26359.AA | Ciliate-A2 | 2-111 | 33 | 6.6e-18 | 58.96 | In-house | 30-144 (272) | Show / Hide |
Range on Protein: 2-111 Range on HMM: 30-144/272 Sequence Identity: 33% (38 aa) FDGVNN-IDKTIYQNAQQEVKVMKTFNHKNVLKVVDYFEIGYYFLIVTERY-ESSLEQWLR--SRQTNQLFLPQIISFSDQLFQALEHIHSKKKEARDID .|| . |.. |... | ...| ||.|. |. | | || | |..| . |.||..| . |.. . |...| |. .|.|..|.| ||. IDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIPDHQFVHFACQILDAIEYLHNKNYVLRDLS LSTIMIDKNNQ-LKV | | ||..|| .|. LRNILIDQDNQIIKL |
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| Kinase | 26359.AA | Ciliate-E6 | 20-90 | 35 | 6.1e-15 | 44.28 | In-house | 1-73 (154) | Show / Hide |
Range on Protein: 20-90 Range on HMM: 1-73/154 Sequence Identity: 35% (26 aa) VKVMKTFNHKNVLKVVDYFEIGYYFLIVTERYESSLEQWLRSRQTNQLFLPQ--IISFSDQLFQALEHIHSKK .. | ||.| || | | | |..|| || | .|..|. . .. . . |. |||.|.|..|||. IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKN |
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| Kinase | 26359.AA | CMGC | 19-90 | 15 | 5.7e-11 | 31.33 | In-house | 71-202 (513) | Show / Hide |
Range on Protein: 19-90
Range on HMM: 71-202/513
Sequence Identity: 15% (21 aa)
EVKVMKTFN-----------------HKNVLKVVDYFEIGY-----------------YFLIVTERYESSLEQWLRSRQT-------NQLFLPQ------
|.| .| .| |.|..| |.| .. .|.| . .| | ... |. . | .
EIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPH
------IISFS------DQLFQALE--HIHSKK
| .|. |....|. ..||..
RRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHW
|
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| Kinase | 26359.AA | Ciliate-E2 | 10-90 | 16 | 4.7e-09 | 27.2 | In-house | 67-180 (365) | Show / Hide |
Range on Protein: 10-90
Range on HMM: 67-180/365
Sequence Identity: 16% (19 aa)
KTIYQNAQ------QEVKVMKTFNHKNVLKVVDYFE--IGYYFLIVTERYES-SLEQWLRSRQTNQLFL---------PQIISFSDQLFQ----------
. |.. . .| ..... ||.|..| ...|. .. .|.| .. .|............. .|. .. |..|
IHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYI
-----ALEHIHSKK
|||..|||.
ACIILALEYLHSKN
|
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| Kinase | 26359.AA | PASK | 19-49 | 38 | 1.3e-07 | 19.53 | In-house | 54-87 (260) | Show / Hide |
Range on Protein: 19-49 Range on HMM: 54-87/260 Sequence Identity: 38% (13 aa) EVKVMKTFN---HKNVLKVVDYFEIGYYFLIVTE |...| | | |.|..||.| || .. .|.| EIHIMQTLNKNPHENIVKVLDFFENDDFYQLVME |
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| Kinase | 26359.AA | Ciliate-C7 | 7-134 | 25 | 2.3e-07 | 20.16 | In-house | 37-164 (164) | Show / Hide |
Range on Protein: 7-134 Range on HMM: 37-164/164 Sequence Identity: 25% (33 aa) NIDKTIYQNAQQEVKVMKT-FNHKNVLKVVDYFE-IGYYFLIVTERYESSLEQWLRSRQTNQLFLPQIISFSDQLFQALEHIHSKKKEARDIDLSTIMID |||. |.. .|||....| . .|.. ...|| ...|. .| . .|.| . . | . | | .. | | .||||. ..|. .. | || NIDQDINNQVQQEINILKQCKDSPYVVCLLHQFEGQQFIYLVLNECQGGTLNQIIERNQNKRLNEISAIKYAKDIAQGLYYIHSKNCVVNDLKMDNILID KNNQLKVVCNGYFNANIFRRVQSLQIQNQK |. .| . |. .. . || .. YNGNAVVC--DFGLADNLTQKSKYQINQYM |
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| Kinase | 26359.AA | Pkinase | 18-90 | 22 | 2.4e-07 | 27.05 | Pfam | 49-128 (293) | Show / Hide |
Range on Protein: 18-90 Range on HMM: 49-128/293 Sequence Identity: 22% (18 aa) QEVKVMKTFNHKNVLKVVDYFEIGYYFLIVTERYES-----SLEQWLRSRQTNQL--FLPQIISFSDQLFQALEHIHSKK .|...|| .||.|... |.|| . . .|.| | .| ... .. . . ..... |....||..||.. SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMG |
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| Kinase | 26359.AA | Ciliate-E2a | 6-90 | 19 | 6.8e-07 | 16.35 | In-house | 36-122 (275) | Show / Hide |
Range on Protein: 6-90 Range on HMM: 36-122/275 Sequence Identity: 19% (17 aa) NNIDKTIYQNAQQEVKVMKTFNHKNVLKVVDYFEIGYYFLIVTERYES-SLEQWLRSRQTNQLFLPQIISFSDQLF-QALEHIHSKK ....|. ... ..|.. |.. .|.|..| ...| .. .|.| .|. .|.. .. .... . .| .. ||. |.|...|... MYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRN |
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| Kinase | 26359.AA | Ciliate-E2-Unclassified | 23-113 | 21 | 1e-06 | 18.84 | In-house | 75-190 (352) | Show / Hide |
Range on Protein: 23-113 Range on HMM: 75-190/352 Sequence Identity: 21% (25 aa) MKTFNHKNVLKVVDYFEIGYYFLIVTERYES-SLEQWLRSR--------------QTNQLFLPQIIS------FSDQLFQALEHIHSKK-KEARDIDLST .. ..| ...| ...|. .. ||.| | .|.|....| .... | | .. . |. |.||..|.|. ||| .. LLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN IMIDKNN---QLKVVC |..|.|. ..|. . ILFDNNGKNYYIKIID |
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| Kinase | 26359.AA | CAMK | 14-90 | 13 | 4e-06 | 14.93 | In-house | 76-199 (425) | Show / Hide |
Range on Protein: 14-90 Range on HMM: 76-199/425 Sequence Identity: 13% (17 aa) QNAQQEVKVMKT-------FNHKNVLKVVDYFE---------IGY-----------YFLIVT---ERYESS-LEQWLRSRQTNQ---------------- .| ..|...||. .|.|..| ...| . | .. .|. | . | . | .. . . KNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERG -LFLPQIISFSDQLFQALEHIHSKK . . . |. .|....||.. RFTEREARRYFRQICSAVHYCHSHN |
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| Kinase | 26359.AA | CAMK-Unique | 19-90 | 16 | 9e-06 | 14.82 | In-house | 66-177 (363) | Show / Hide |
Range on Protein: 19-90 Range on HMM: 66-177/363 Sequence Identity: 16% (18 aa) EVKVMKTFNHKNVLKVVDY----FEIGY---------------YFLIVTERYESS-LEQWLRSR-----------------QTNQLFLP---QIISFSDQ |. ..|. .| | .|..|. |. |. ||.|. . | .|. .. . .. | .... . . EHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQC LFQALEHIHSKK | .|... ||.. LLSAVAYMHSQD |
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| TPR_2 | 26359.AA | TPR_2 | 241-274 | 23 | 0.095845 | 10.26 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 241-274 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) QQYYQAVGDFYKSIQKYDDSAQAYKKCLQEGKEN .. . |. | ..||. ...|.|.|. .| AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_2 | 26359.AA | TPR_2 | 449-482 | 32 | 0.000351 | 18.88 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 449-482 Range on HMM: 1-34/34 Sequence Identity: 32% (11 aa) GFCYVHLANYYQHQFKYNEAIQIMDQCLNNSPNN .. |.. | .| .| |||. ....| ||| AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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