Gene 25478 (Tetrahymena)

25478

Species: Tetrahymena
Alias: 951, TTHERM_00736530, 120.m00136, 25478, PreTt25478
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
25478.AA Protein None 1386 None Fasta, JSON
25478.kin_dom Protein Kinase Domain None 49 None Fasta, JSON
25478.NA RNA None 4161 None Fasta, JSON

Protein domain

Protein domains of 25478.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 25478.AA CK1 195-233 36 5.3e-10 31.15 In-house 139-193 (339) Show / Hide 
Range on Protein: 195-233
Range on HMM: 139-193/339
Sequence Identity: 36% (20 aa)

VQLFDKLRKMHEKGLAHSDIKPANIVMGF-----------D-----RQFYLIDFG
.|. . |. ||..|  | ||||.|..||            .     ||.|.||||
IQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFG
Kinase 25478.AA TTBKL 201-233 42 8.2e-09 25.96 In-house 115-154 (288) Show / Hide 
Range on Protein: 201-233
Range on HMM: 115-154/288
Sequence Identity: 42% (17 aa)

LRKMHEKGLAHSDIKPANIVMGFD-------RQFYLIDFG
|. ||..|  | |.||.|...|.        | .||||||
LKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFG
Kinase 25478.AA Ciliate-A1 169-235 28 1.7e-08 24.96 In-house 86-148 (301) Show / Hide 
Range on Protein: 169-235
Range on HMM: 86-148/301
Sequence Identity: 28% (19 aa)

NNIRDNILQKDYQKKQAFIPFAKCLIVQLFDKLRKMHEKGLAHSDIKPANIVMGFDRQFYLIDFGAS
.|  . . |.|| ||   . .     .|..  .  .|..   |.|.|| ||...|| .. ..|.| |
GNLFNYCYQNDYMKKEEIYEI----CYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLGMS
Kinase 25478.AA Ciliate-B2 193-253 29 1.7e-08 16.0 In-house 109-169 (197) Show / Hide 
Range on Protein: 193-253
Range on HMM: 109-169/197
Sequence Identity: 29% (18 aa)

LIVQLFDKLRKMHEKGLAHSDIKPANIVMGFDRQFYLIDFGASVEIQEQNEDYLKCYTESF
.| ||.| | ... .   | ||||.|| .    .. . ||| |  ....   . |  | ..
MIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKY
Kinase 25478.AA Ciliate-E5 201-235 48 8.9e-08 21.17 In-house 116-150 (271) Show / Hide 
Range on Protein: 201-235
Range on HMM: 116-150/271
Sequence Identity: 48% (17 aa)

LRKMHEKGLAHSDIKPANIVMGFDRQFYLIDFGAS
| . |.|.  | |||||||..| |     ||.| |
LQDIHQKNIIHLDIKPANILLGYDNKWKYIDMGIS
Kinase 25478.AA Ciliate-B3 189-253 27 9.6e-08 24.56 In-house 1-69 (69) Show / Hide 
Range on Protein: 189-253
Range on HMM: 1-69/69
Sequence Identity: 27% (19 aa)

FAKCLIVQLFDKLRKMHEKGLAHSDIKPANIVMGFDRQ----FYLIDFGASVEIQEQNEDYLKCYTESF
||  .  |. .|....||| . | |||  ||..    .      .||||   . ..       | |...
FALKHFHQVVEKIKILHEKNICHCDIKVDNILVNQQDKENYKVIIIDFGHCQRKCQNCKSEMICGTLTY
Kinase 25478.AA CK1-A 193-233 43 1.1e-07 23.1 In-house 100-143 (261) Show / Hide 
Range on Protein: 193-233
Range on HMM: 100-143/261
Sequence Identity: 43% (19 aa)

LIVQLFDKLRKMHEKGLAHSDIKPANIVMGFDR---QFYLIDFG
|  |.  ..  .|||.  | |||| | .|| .|   . .|||||
LADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFG
Kinase 25478.AA Ciliate-E2 204-253 20 1.1e-07 22.4 In-house 176-253 (365) Show / Hide 
Range on Protein: 204-253
Range on HMM: 176-253/365
Sequence Identity: 20% (17 aa)

MHEKG-LAHSDIKPANIVMGFDRQFYLIDFGASVEIQEQNEDYLK--------------------------------CYTESF
.|.|.   | |||| ||..       .|||| | .....|.....                                |.|  .
LHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGY
Kinase 25478.AA NZAK 205-254 37 1.1e-07 21.41 In-house 122-172 (329) Show / Hide 
Range on Protein: 205-254
Range on HMM: 122-172/329
Sequence Identity: 37% (19 aa)

HEKGLAHSDIKPANIVMGFDRQFYLIDFGASVEIQEQ-NEDYLKCYTESFN
| ..  | |||..|... | ..  |||||.|.  | .  |.||   |.  |
HKHHIIHRDIKSNNVILDFNKNLKLIDFGSSIIQQQYQFEQYLNETTNNNN
Kinase 25478.AA Ciliate-E2b 201-250 30 1.3e-07 19.37 In-house 115-164 (272) Show / Hide 
Range on Protein: 201-250
Range on HMM: 115-164/272
Sequence Identity: 30% (15 aa)

LRKMHEKGLAHSDIKPANIVMGFDRQFYLIDFGASVEIQEQNEDYLKCYT
|.  |...  . |||| ||    . . .|||.|..  ....||   ...|
LEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFT
S_TKc 25478.AA S_TKc 81-329 14 2.4e-05 -98.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 81-329
Range on HMM: 1-231/231
Sequence Identity: 14% (42 aa)

FIKQQKIQQGQ-----KAKELAPGGCSNRVLLNCYDGIFFIQKKCKSEQDASKERGFIKILSEEGITLPLIERTESDSGGLFYVEQAAGVQSLNNIRDNI
. . .|| .|      |...               .|  .  |. |  ... .|.   |    . |   |..  .. .   .  | . |  .| . .| |
YEILRKIGKGAFGKVYKCRHKK-------------TGRIVAIKIIK--EHIRREIQILKK-HHPNI-VKLYDVFQD-DHLYMVMEYCDG--DLGDLFDYI

LQKDYQKK-QAFIPFAKCLIVQLFDKLRKMHEKGLAHSDIKPANIVMGFDRQFYLIDFGASVEIQEQNEDYLKCYTESFNTVWY-----LQNRPKKRKDI
 .. .... . | . |.... |... |  .|..|  | |.||.|| .    .  ..||| . ..           |    | ||     |          
KKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----------

IRCDN-----------CQLSLTIIRLLMDSIQDKKFKQFNQMDDKKFLDLVSQIFKKFQS---QSNPNEN-------RDLF
   .                |.   .     ... ||.     .. ..|.......|  .         .          |
-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 25478.AA Pkinase 204-250 23 3.9e-05 19.22 Pfam 124-170 (293) Show / Hide 
Range on Protein: 204-250
Range on HMM: 124-170/293
Sequence Identity: 23% (12 aa)

MHEKGLAHSDIKPANIVMGFDRQF----YLIDFGASVEIQEQNEDYLKCYT
.|..|  | |.||.|| .  . .      ..||| .  ..  .  .  ..|
CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTT