Gene 24858 (Tetrahymena)

24858

Species: Tetrahymena
Alias: 24858, PreTt24858, TTHERM_00388630, 1125, 41.m00265
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
24858.AA Protein None 1275 None Fasta, JSON
24858.kin_dom Protein Kinase Domain None 46 None Fasta, JSON
24858.NA RNA None 3828 None Fasta, JSON

Protein domain

Protein domains of 24858.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 24858.AA Ciliate-E2-Unclassified 191-280 18 6.6e-07 20.02 In-house 136-262 (352) Show / Hide 
Range on Protein: 191-280
Range on HMM: 136-262/352
Sequence Identity: 18% (24 aa)

TEEEIL-----NTLESVLLGICELHKNN-IIHGDFNASSVVFCDDG---FVKIAD-QFVTNPD--------------VYQKEKVQQF--QQSYL----PP
||....     . .  .|.|.. ||..| ||| |   . ..| ..|    .||.| ..  ...              ...... ..|    .|.    .|
TEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAP

EKTFYTAEG-------DFWAIGMVFLE
|       .       |.|. |... |
EVLQGQNYDHSKAYKCDIWSLGVILYE
Kinase 24858.AA Ciliate-E1 190-262 22 1e-06 18.01 In-house 106-181 (202) Show / Hide 
Range on Protein: 190-262
Range on HMM: 106-181/202
Sequence Identity: 22% (17 aa)

WTEEEILNTLESVLLGICELHKNNIIHGDFNASSVVFCDDGFVKIADQFVT---NPDVYQKEKVQQFQQSYLPPEK
.|......     . |..||| .||||.| . . ......|  ...|. .    .   .|  .. .....| |||.
FTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQ
Kinase 24858.AA STE 192-236 28 5e-06 17.42 In-house 150-190 (359) Show / Hide 
Range on Protein: 192-236
Range on HMM: 150-190/359
Sequence Identity: 28% (13 aa)

EEEILNTLESVLLG-ICELHKNNIIHGDFNASSVVFCDDGFVKIAD
|..|   . ..| |    ||...||| |  .. . .     ||..|
ESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCD
Kinase 24858.AA Ciliate-A5 130-262 17 8e-06 16.19 In-house 68-177 (275) Show / Hide 
Range on Protein: 130-262
Range on HMM: 68-177/275
Sequence Identity: 17% (25 aa)

KFGVVFDNFIRDFDSELETRKGNKKNILSSMKENGVVLHSKDQIHQGLLIMSKVNSIQLFWTEEEILNTLESVLLGICELHKNNIIHGDFNASSVVFCDD
|.. ..  .  .  .|.. || ..|                                  |..| |.   . ...   . |..|||.|||   ...   .|
KVNCYYEYHDNNLEQEMQMRKQCQKD--------------------------------IFYNEQELWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQD

GFVKIADQF-------VTNPDVYQKEKVQQFQQS--YLPPEK
|.||..|         ..|.  |.  .   . ..  || |..
GQVKLMDMNESKDFFYQINWSSYKQYQHHMSTENKQYLSPMQ
Kinase 24858.AA Ciliate-E2b 201-236 30 1.8e-05 12.74 In-house 110-145 (272) Show / Hide 
Range on Protein: 201-236
Range on HMM: 110-145/272
Sequence Identity: 30% (11 aa)

SVLLGICELHKNNIIHGDFNASSVVFCDDGFVKIAD
|..|.. .||..|||..|   . .  . .|..|..|
SICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLID
Kinase 24858.AA TAO 192-236 35 2.5e-05 13.07 In-house 98-142 (254) Show / Hide 
Range on Protein: 192-236
Range on HMM: 98-142/254
Sequence Identity: 35% (16 aa)

EEEILNTLESVLLGICELHKNNIIHGDFNASSVVFCDDGFVKIAD
|.||    . .| |.  ||. . || |  |. ..  ..| ||.||
EVEIAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLAD
Kinase 24858.AA SAK 190-236 34 6e-05 12.5 In-house 97-143 (254) Show / Hide 
Range on Protein: 190-236
Range on HMM: 97-143/254
Sequence Identity: 34% (16 aa)

WTEEEILNTLESVLLGICELHKNNIIHGDFNASSVVFCDDGFVKIAD
.||||  . .. .. |.  ||  .|.| |   | ..   |  .||||
FTEEEARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIAD
Kinase 24858.AA Ciliate-E2 191-278 17 6.7e-05 12.73 In-house 143-286 (365) Show / Hide 
Range on Protein: 191-278
Range on HMM: 143-286/365
Sequence Identity: 17% (26 aa)

TEEEILNTLESVLL---------------GICELHKNN-IIHGDFNASSVVFCDDGFVKIAD-QFVTNPDVYQKEKVQQFQQS-----------------
||.||..  . .|                .. .||..| ||| |   . ..|     .||.|  . .. |  .... . .||.                 
TEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMD

----------------YLPP----EKTF--------YTAEGDFWAIGMVF
                |..|     |          |. . |.|..|...
QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase 24858.AA SLK 191-236 32 0.000101 11.73 In-house 95-140 (259) Show / Hide 
Range on Protein: 191-236
Range on HMM: 95-140/259
Sequence Identity: 32% (15 aa)

TEEEILNTLESVLLGICELHKNNIIHGDFNASSVVFCDDGFVKIAD
||. |    . .. ..  ||.|..|| |  |  ...  || |..||
TEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLAD
Kinase 24858.AA CDK10 202-236 40 0.000132 11.65 In-house 109-143 (285) Show / Hide 
Range on Protein: 202-236
Range on HMM: 109-143/285
Sequence Identity: 40% (14 aa)

VLLGICELHKNNIIHGDFNASSVVFCDDGFVKIAD
.| |.  ||.| .|| |   | ... |.| .|.||
MLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVAD
S_TKc 24858.AA S_TKc 57-367 10 0.000144 -109.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 57-367
Range on HMM: 1-231/231
Sequence Identity: 10% (37 aa)

YKILLQL-----SSQLLLENTVNGKRVIYKEFAIPQNKGFQEMQSELMRRKAIDCNNILKLNLFLIEKQQTKKPLSDQKFGVVFDNFIRDFDSELETRKG
|.|| ..     ..  .  ..  |..|  |.                                                     ....|  .   . .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------------------------------EHIRREIQILKK-HHP

NKKNILSSMKENGVVLHSKDQIHQGLLIMSKVNS--------IQLF--------WTEEEILNTLESVLLGICELHKNNIIHGDFNASSVVFCDDGFVKIA
|  ... .. .           .   ..|  ..         |.           .| ..   .  .....  .|...||| |   . . ...   .||.
NIVKLYDVFQD-----------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKIC

D-----QFVTNPDVYQKEKVQQFQQS--YLPPEKTFYTA-EGDFWAIGMVFLEAAILESSQDLYSFKFENLQSCQENQSEDIYQINFKLLQSRIQDLVLL
|     |.              |  .  |..||   |.  . | |..| .. | .  .   .               | . ....               
DFGLARQL------------TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP---------------QMQMMFKKIG-------------

SQSQNKQNQLQTVLNLLLSKEPSKRGEALLHFE----ALKHYYS
        ..   .. .| |.|.||  |   ..    . .| . 
------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 24858.AA Ciliate-E1 1146-1210 17 0.17791 1.15 In-house 3-68 (202) Show / Hide 
Range on Protein: 1146-1210
Range on HMM: 3-68/202
Sequence Identity: 17% (12 aa)

SGDSFQVFKASEQSTH-REKQASCKKLNINELRSQLEQNSILQNNLKKPTPQNI-QIRIQNFIYDDD
.|....||||  |... ....    ....|.   ......  .....|   ... .| |...|..|.
NGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQ
MORN 24858.AA MORN 1237-1259 30 0.012473 14.31 Pfam 1-23 (23) Show / Hide 
Range on Protein: 1237-1259
Range on HMM: 1-23/23
Sequence Identity: 30% (7 aa)

YHGEFLMGKLNGYGSFYIGQQNT
| ||. .|| .|.| ..    ..
YEGEWKNGKMHGHGVYTWPDGDR
MORN 24858.AA MORN 1214-1236 21 0.084166 11.3 Pfam 1-23 (23) Show / Hide 
Range on Protein: 1214-1236
Range on HMM: 1-23/23
Sequence Identity: 21% (5 aa)

YDGQYFNNTFSGVGFLKLKNNCS
|.|.. |. . | | .. .. . 
YEGEWKNGKMHGHGVYTWPDGDR