Gene 24200 (Tetrahymena)

24200

Species: Tetrahymena
Alias: 832, 24200, 193.m00037, TTHERM_01006430, PreTt24200
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
24200.AA Protein None 389 None Fasta, JSON
24200.kin_dom Protein Kinase Domain None 263 None Fasta, JSON
24200.NA RNA None 1170 None Fasta, JSON

Protein domain

Protein domains of 24200.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 24200.AA CAMK 246-321 20 3e-13 38.32 In-house 182-291 (425) Show / Hide 
Range on Protein: 246-321
Range on HMM: 182-291/425
Sequence Identity: 20% (22 aa)

KSYVLDILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGV------------RRVKVGDFGLCHKVDEKTGLA---------------------YVKYNCG
. |.  |..... .|| . ||.|.|. |. .  .. .                .|. |||.  |.|.. ..                        |  ||
RRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

TFGFKA-PEI
| .. | ||.
TPEYMAAPEV
Kinase 24200.AA WEE 224-299 27 1.1e-12 38.95 In-house 92-183 (297) Show / Hide 
Range on Protein: 224-299
Range on HMM: 92-183/297
Sequence Identity: 27% (26 aa)

NLIQFESVQHKSHSPIKNELKMKSYVLDILEGLKQIHSE-GYVHLDIKLSNLYCIRKE----------------IEGVRRVKVGDFGLCHKVD
||.||   |...  ..  | . . . .||..||. |||. | ||.||| .|.. ..|                 ..   . | ||||.. ...
NLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFN-MMCKIGDFGHVTDMN
Kinase 24200.AA Ciliate-E2 248-321 25 3.1e-10 31.31 In-house 165-258 (365) Show / Hide 
Range on Protein: 248-321
Range on HMM: 165-258/365
Sequence Identity: 25% (27 aa)

YVLDILEGLKQIHSEG-YVHLDIKLSN-LYCIRKEIEGVRRVKVGDFGLCHKVDEK---------TGLAYVKYN---------------------CGTFG
|.  |...|. .||..  .| |||..| |.           .|. ||||. |.|..          ..     |                     ||| |
YIACIILALEYLHSKNNIIHRDIKPENILF-----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPG

FKAPEI
..||||
YMAPEI
Kinase 24200.AA ULK 241-321 21 2.1e-09 29.56 In-house 124-218 (324) Show / Hide 
Range on Protein: 241-321
Range on HMM: 124-218/324
Sequence Identity: 21% (21 aa)

NELKMKSYVLDILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGVRR--------VKVGDFGLCHKVDE-KTGLAYVKYNC------GTFGFKAPEI
.| . ...  .|..|.| .|.....| |||..|.    . .    .        .|..|||.. .||.        .. .      ||  . ||.|
SEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKT-DSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQI
Kinase 24200.AA ULK 241-321 24 4.4e-09 27.94 In-house 128-222 (329) Show / Hide 
Range on Protein: 241-321
Range on HMM: 128-222/329
Sequence Identity: 24% (24 aa)

NELKMKSYVLDILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGVRR--------VKVGDFGLCHKVDEK-----TGLAYV---KYNCGTFGFKAPEI
.| . ...  .||.|.| .|.....| |||..|     . .    .        .|..|||.. .||.        ...|   .. |||  . ||.|
SEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKT-DSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRL-CGTPLYMAPQI
Kinase 24200.AA MLCK 252-321 37 9.6e-09 18.63 In-house 106-170 (257) Show / Hide 
Range on Protein: 252-321
Range on HMM: 106-170/257
Sequence Identity: 37% (26 aa)

ILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGVRRVKVGDFGLCHKVDEKTGLAYVKYNCGTFGFKAPEI
|.||.. .|. ..||||.|  |  |  ..     ..|. ||||  |.|..     ||...||  | |||.
ICEGVHHMHWQNIVHLDLKPENIMCQTRT---SHQIKIIDFGLARKYDPDEKK--VKVMFGTPEFVAPEV
Kinase 24200.AA Pkinase 242-321 33 3.5e-08 30.01 Pfam 107-182 (293) Show / Hide 
Range on Protein: 242-321
Range on HMM: 107-182/293
Sequence Identity: 33% (27 aa)

ELKMKSYVLDILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGVRRVKVGDFGLCHKVDEKTGLAYVKYNCGTFGFKAPEI
|   |.|.. ||.||. .||.| .| |.|..|. . ..   .  .||..||||. ..|        .  ||| .. |||.
EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEV
Kinase 24200.AA CDK-DD1 246-274 41 3.9e-08 20.59 In-house 101-129 (379) Show / Hide 
Range on Protein: 246-274
Range on HMM: 101-129/379
Sequence Identity: 41% (12 aa)

KSYVLDILEGLKQIHSEGYVHLDIKLSNL
| ..   |||....|. |  |.||| .||
KCFFHQLLEGINECHNQGIMHRDIKPANL
Kinase 24200.AA C8 250-332 24 4.4e-08 24.25 In-house 130-226 (226) Show / Hide 
Range on Protein: 250-332
Range on HMM: 130-226/226
Sequence Identity: 24% (24 aa)

LDILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGVRRVKVGDFGLCHKVDEKTGLAYVKYN--CGTFGFKAPEIKDN-------------SYAINMVL
. ...|.  ||.   .| |||..|.    .. .|   .|  |||.  .| .     . |    |||... ||||                .. . .||
IQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGF-EIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 24200.AA PLK1 242-321 33 4.5e-08 22.35 In-house 98-170 (253) Show / Hide 
Range on Protein: 242-321
Range on HMM: 98-170/253
Sequence Identity: 33% (27 aa)

ELKMKSYVLDILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGVRRVKVGDFGLCHKVDEKTGLAYVKYNCGTFGFKAPEI
|   . |.  |.|| . .|    .| |.|| ||.     ..   .||.|||||  |....      |  |||  . |||.
EPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLF-----LNDHLQVKIGDFGLATKCEYDG--ERKKTLCGTPNYIAPEV
Kinase 24200.AA PLK2 248-294 40 6.8e-08 21.2 In-house 108-149 (257) Show / Hide 
Range on Protein: 248-294
Range on HMM: 108-149/257
Sequence Identity: 40% (19 aa)

YVLDILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGVRRVKVGDFGL
| . |..||.  |. . .| | ||.|.. | .  |    ||.|||||
YMRQIVSGLRYLHQQCIIHRDLKLGNFF-INDNME----VKIGDFGL
Kinase 24200.AA S_TKc 59-386 11 5.6e-07 -74.6 SMART 15-231 (231) Show / Hide 
Range on Protein: 59-386
Range on HMM: 15-231/231
Sequence Identity: 11% (40 aa)

VYLAFDTIFEKQVVVKKIFKNKLDDYQIEQARIECQIACNVNHFNLCKGYYSYENDEEFGIFMEYVDDAEYLVEKIENHGDKFQRKKCEKPYYICDIASP
||.. ..   ..| .|.|                                                                                  
VYKCRHKKTGRIVAIKIIK---------------------------------------------------------------------------------

SDQINCDINQSKFLTLIKANQSNQTNQNYYQSIKVILLASLLASYLFSFIYPQIKTIQ-SICLIHLNLIQF--ESVQHKSHSPIK-------NELKMKSY
                                ....   ..| .    .|   . ..| .   . . ..     .. .  ..  .       .|   ..|
--------------------------------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

VLDILEGLKQIHSEGYVHLDIKLSNLYCIRKEIEGVRRVKVGDFGLCHKVDEKTGLAYVKYNCGTFGFKAPEIKDNSYAI-------------NMVLAQF
.  |...|. .|| | .| |.| .|. . .       ..|..||||. ..         .  |||  . |||.   .|                |.  . 
MYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL---------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYP

PSEPSTGKRDPQNLNNSLKSSSMQTPKTV-----LLSKKPQK-IPGSQLQT-----DHLSLF
| .      ..| . . ..     .|        .| | |.| .   .. .          |
PFP------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 24200.AA CAMK 59-139 16 1.2e-05 13.43 In-house 10-160 (425) Show / Hide 
Range on Protein: 59-139
Range on HMM: 10-160/425
Sequence Identity: 16% (25 aa)

VYLAFDTIFE------------KQVVVKKIFKNKLD--------------------------DYQIEQARIECQIACN-------VNHFNLCKGYYSYEN
|.|....               ..| .| | |.||.                          ..  .. | | .|  .       ..| |..| |  ||.
VKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYED

-------------------DEEFGIFM---EYVDDA---EYLVEKIENHGD
                   |... ..|   ||..     ..| ..|  ||.
PHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGC
Kinase 24200.AA Pkinase 59-125 28 0.002153 13.08 Pfam 15-83 (293) Show / Hide 
Range on Protein: 59-125
Range on HMM: 15-83/293
Sequence Identity: 28% (20 aa)

VYLAFDTIFEKQVVVKKIFKNKLDDYQIEQARI--ECQIACNVNHFNLCKGYYSYENDEEFGIFMEYVD
||.. .   .|.|.||.| | . .. . ...|   |.||  ..|| | .. |...|.. .  . |||..
VYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCE
Kinase 24200.AA ULK 59-126 18 0.064604 2.58 In-house 15-104 (329) Show / Hide 
Range on Protein: 59-126
Range on HMM: 15-104/329
Sequence Identity: 18% (17 aa)

VYLAFDTIFE----KQVVVKKIF-----KNKLD---DYQIEQARIECQIACNVN--------HFNLCKGYYSYENDEE--FGIFMEYVDD
|| ... . .    ..|..|.|      ... .   .|.... . |..|    .        | | .| |  .|.. .  . |.||| ..
VYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNG