Gene 22063 (Tetrahymena)
22063
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 22063.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 22063.AA | S_TKc | 26-296 | 11 | 2.2e-08 | -54.07 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 26-296 Range on HMM: 1-231/231 Sequence Identity: 11% (35 aa) CVKLENCGEGGFGTVDAYYDNNLQKVIAVKTVSRKTTYLQEKRRLINLKKQQLDFVNNLIGFCD-QERILVFELGEATLLEIDDMFQDDGY-----TWRE .|. |.|.||.| .... ... |.| .. . ..| . | . . ... .|..... .. .|.|. . | . |. .. |. | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK----HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE IDLIYIAWNLLVGLKYLREIKSFHGDISPNNIMFFMEKVKYIDLGSSEINKNNQYLQQYKIEFVNHEIRKNKANFKYSDEQI--------------T-QN . .... .. .|.|. . . | |. | ||.. .| .| |.. . . .. . -HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL----------------------------TTFCGTPWYMAPEVLGYGKCKC EIFALGKTLLYLAL----YNDNDKNHFIMDVDKKSQKQLIEMQKAHFYELVANDSLSNSYPQLKNLIIKMMYPFDIDLNDIDQNLS-QSEDKEDSIK . ..| .| .. . . .... . |..|..| |.. . . . | ... | . DWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 22063.AA | Ciliate-E2-Unclassified | 27-174 | 17 | 1e-06 | 18.91 | In-house | 2-203 (352) | Show / Hide |
Range on Protein: 27-174 Range on HMM: 2-203/352 Sequence Identity: 17% (36 aa) VKLENCGEGGFGTVDAYYDNN---------LQKVIAVKTVSRKTTYLQEKRRLINLKKQQLDFVNN-------------------LIGFCDQER---ILV ... .|.||||.| .... . |.. .| . .. .... .. ..... .... .|.| . ..| KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV FELGEATLLEI----------------DDMFQDDGYTWREIDLI---YIAWNLLVGLKYLREIK-SFHGDISPNNIMFFME----KVKYIDLGSS-EINK |. | |. ..| |. | ... . .... .|.||.|| . . | || |.||.| . ..| ||.|.| .... MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ NNQY ||.. NNNC |
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Kinase | 22063.AA | Ciliate-E1 | 32-207 | 17 | 3e-06 | 16.85 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 32-207 Range on HMM: 1-202/202 Sequence Identity: 17% (36 aa) CGEGGFGTVDAYYDNNLQ-KVIAVKTVSRKTTYLQE----KRRLINLKKQQLDFVNNLIGFCDQER-------ILVFELGEATLLEIDD---------MF |.|.|. | . .| . ...|.| . .. | |. . . ... .. . . ..| ..|. . |..||. . .|.. . .. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC QDDGYTWREIDLIYIAWNLLVGLKYLREIKSFHGDISPNNIMFFM-EKVKYIDLGSSEI-NKNNQYLQQYKIEFVNHEIRKNKA----NFKYSDEQITQN | . . . ...|. .|. || .|. . |.|| | || . .. .| |.| | . ..|... .||| . . . . ..... . QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS EIF .|. DIY |
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Kinase | 22063.AA | Ciliate-E2 | 119-174 | 26 | 7e-06 | 16.06 | In-house | 144-211 (365) | Show / Hide |
Range on Protein: 119-174 Range on HMM: 144-211/365 Sequence Identity: 26% (19 aa) EIDLIYIAWNLLV---------------GLKYLREIK-SFHGDISPNNIMFFMEKVKYIDLGSSEINKNNQY | .|| . .| .|.|| . . .| || |.||.| .| ||.| | ....... EKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQ |
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Kinase | 22063.AA | STE | 122-166 | 36 | 0.000232 | 11.45 | In-house | 153-194 (359) | Show / Hide |
Range on Protein: 122-166 Range on HMM: 153-194/359 Sequence Identity: 36% (17 aa) LIYIAWNLLVG-LKYLREIKSFHGDISPNNIMFFMEKVKYIDLGSS ..||. .| | |.|| . . | || | ||.. || .| | . IAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVC |
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Kinase | 22063.AA | YSK | 27-57 | 41 | 0.000236 | 8.62 | In-house | 2-32 (257) | Show / Hide |
Range on Protein: 27-57 Range on HMM: 2-32/257 Sequence Identity: 41% (13 aa) VKLENCGEGGFGTVDAYYDNNLQKVIAVKTV .|.| | | || | .|| |.|.|.|.. TKQECIGRGSFGEVYKGIDNRTQRVVAIKII |
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Kinase | 22063.AA | CMGC | 26-166 | 15 | 0.000378 | 8.51 | In-house | 1-251 (513) | Show / Hide |
Range on Protein: 26-166 Range on HMM: 1-251/513 Sequence Identity: 15% (39 aa) CVKLENCGEGGFGTVDAYYD--------------NNLQKVIAVKTVSRKTTYL-QEK----------RRLINLKK-QQL----------------DFVNN ... .||| .|.| .| .. ....|.| .... | |.| | | .| ..| . || YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN LIG---FCDQER-------------------ILVFELGEATLLEIDDMFQDD-----GYTWREID------------LIYIA------WNLLVGLK--YL ... .. . ||||. . .|... .. |.| . | |. . .| ||| |. IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC REIK--SFHGDISPNNIMFFMEK---------------------VKYIDLGSS . .| |. | ||.. .. .| .| |.. HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA |