Gene 17269 (Tetrahymena)

17269

Species: Tetrahymena
Alias: 17269, 1094, PreTt17269, 580.m00004, TTHERM_01709380
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
17269.AA Protein None 369 None Fasta, JSON
17269.kin_dom Protein Kinase Domain None 59 None Fasta, JSON
17269.NA RNA None 1110 None Fasta, JSON

Protein domain

Protein domains of 17269.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 17269.AA C8 110-191 52 1.5e-35 120.86 In-house 1-81 (226) Show / Hide 
Range on Protein: 110-191
Range on HMM: 1-81/226
Sequence Identity: 52% (43 aa)

TNNFQILSFGSFGMVLATKKAKLDKKEIVLKIQKIEDEQHIQNEISIMQKLKEPLVVQLYDSYIIENKIGPDRYSVFELEKC
.||||.||||..||||..|..| |..|||||.||....|.|||..|||.....|.|.|.||.|..|.......|.|||.|||
FNNFQYLSFGAYGMVLKAKNVK-DNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKC
Kinase 17269.AA Ciliate-C8 119-191 31 1.3e-28 99.74 In-house 1-96 (238) Show / Hide 
Range on Protein: 119-191
Range on HMM: 1-96/238
Sequence Identity: 31% (30 aa)

GSFGMVLAT------KKAKLDKKEIVLKIQKIEDEQHIQNEISIMQKLKEPLVVQLYDSYIIENKIGPDR-----------------YSVFELEKC
|.|||||..      .| .|...|.|.||||...|. |.....|||....|.|||.||........ ...                 ..|.|.|||
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKC
Kinase 17269.AA C8 209-238 60 2e-14 46.54 In-house 197-226 (226) Show / Hide 
Range on Protein: 209-238
Range on HMM: 197-226/226
Sequence Identity: 60% (18 aa)

YSAPEILNKQDNELKVYSKKSDSYSVGLLL
|.||||..||||..| |...||..||||.|
YFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 17269.AA Ciliate-C8 209-238 54 3e-13 44.14 In-house 208-238 (238) Show / Hide 
Range on Protein: 209-238
Range on HMM: 208-238/238
Sequence Identity: 54% (17 aa)

YSAPEILNK-QDNELKVYSKKSDSYSVGLLL
|.|||...| ........|||||||||||.|
YFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 17269.AA C2 119-191 20 1.8e-12 39.02 In-house 1-101 (245) Show / Hide 
Range on Protein: 119-191
Range on HMM: 1-101/245
Sequence Identity: 20% (21 aa)

GSFGMVLATKKAKLDKKEIVLKIQKIED-----EQHIQNEISIMQKLK-EPLVVQLYDSYIIENKIGPD-------------R----------YSVFELE
|.||.|| .   | ......||||....     .. .|.|..||....  |.....|...    .   |             .            |.|.|
GAFGLVLKA-FNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE

KC
.|
FC
Kinase 17269.AA S_TKc 110-310 18 1.6e-07 -66.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 110-310
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

TNNFQILSFGSFGMVLATKKAKLDKKEIVLKIQKIEDEQHIQNEISIMQKLKEPLVVQLYDSYIIENKIGPDRYSVFELEKC--XXCLDSRQQR------
    ...  |.|| |   .. | ....  .|| |    .||..||.|..| . | .|.|||..        . | |.|.        .|  ..|      
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FNSSYRR-----------------------------------------------------YSAPEILNKQDNELKVYSK-KSDSYSVGLLLAFLDNYQ
  |.    |                                                     | |||.|         |.| |.| .|.| .|. .    
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL--------GYGKCKCDWWSCGCILYEM----

DLKKNAPFTFLLMTKKQLDKPFEKSKIKINKNSEIYKFINLLVVSDSGQRSSLYDIVE-QSD---TKLL
 |    ||        |... |.| .      .|   ||. . . |  .| .  .. . ..|      .
-LCGYPPFP-------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 17269.AA CMGC 113-188 14 5.9e-07 17.9 In-house 1-136 (513) Show / Hide 
Range on Protein: 113-188
Range on HMM: 1-136/513
Sequence Identity: 14% (20 aa)

FQILS---FGSFGMVLATKKAKLD-------------KKEIVLKIQKIEDEQHIQ---------------NEISIMQKLK-----------------EPL
..|..    |..|.|   .  . .             .... .|. | .   ..|                ||.|...|.                 .. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVQLYDSYIIEN--KIGP-----------DRYSVFEL
.|.|||..  .|  . ..           . | |||.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEY
Kinase 17269.AA CAMK 115-172 18 5.9e-07 17.68 In-house 1-107 (425) Show / Hide 
Range on Protein: 115-172
Range on HMM: 1-107/425
Sequence Identity: 18% (20 aa)

ILSFGSFGMVLATKKAKLDK-----------KEIVLKI---QKIE----------------------------DEQHIQNEISIMQK-------LKEPLV
.|  |||| |   .  .  .           ..   ||   .|.                             |.. ...||.||.|       |. | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYDSY
..||. |
IKLYEVY
Kinase 17269.AA MLCK 140-172 36 1e-06 12.9 In-house 33-65 (257) Show / Hide 
Range on Protein: 140-172
Range on HMM: 33-65/257
Sequence Identity: 36% (12 aa)

KIQKIEDEQHIQNEISIMQKLKEPLVVQLYDSY
|..| .|.. ..|||.|| .|  | ..|..|..
KCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAF
Kinase 17269.AA STE20 119-178 25 3e-06 19.36 In-house 10-83 (288) Show / Hide 
Range on Protein: 119-178
Range on HMM: 10-83/288
Sequence Identity: 25% (19 aa)

GSFGMVLATKKAKLDKKE---IVLKIQKIED-------EQHIQNEISIMQKLKEPLVVQLYDSYIIE----NKI
||.| |    . . ....   .  |. ..|.       .. ||.|||||...| | .|. |.||. .    ...
GSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDEL
Kinase 17269.AA STE 110-178 16 2.3e-05 15.04 In-house 1-112 (359) Show / Hide 
Range on Protein: 110-178
Range on HMM: 1-112/359
Sequence Identity: 16% (18 aa)

TNNFQILSFGSFG-MVLATKKAKL-------------DKKEIVLKIQKI--------------------EDEQHIQNEISIMQKLK--EPLVVQLYDSYI
  . ...  |.||  ..| .. .               .. .  |. ..                    |..| |..||.||.|..   | .|. |..|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

IE-------NKI
 |       ...
KEGHNHKNDDEL
Kinase 17269.AA Ciliate-E2 110-178 20 9.4e-05 12.22 In-house 1-109 (365) Show / Hide 
Range on Protein: 110-178
Range on HMM: 1-109/365
Sequence Identity: 20% (22 aa)

TNNFQILSFGSFG-----MVLATKKA-----------------KLDKKEIVLKIQK------IEDEQHIQNEIS----------IMQKLKEPLVVQLYDS
 .  ... .|.||      |  ..|                  | ..|.. .||.|      |. |.|| .||           |...|. | ....|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YI--IENKI
..   .|.|
FQEKDDNNI
Kinase 17269.AA Ciliate-E2 209-238 41 0.000335 10.3 In-house 253-286 (365) Show / Hide 
Range on Protein: 209-238
Range on HMM: 253-286/365
Sequence Identity: 41% (14 aa)

YSAPEILNKQDNE----LKVYSKKSDSYSVGLLL
| ||||||.....     | |..|.| .|.| .|
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase 17269.AA STE-Unique 111-173 25 0.000388 9.94 In-house 1-71 (616) Show / Hide 
Range on Protein: 111-173
Range on HMM: 1-71/616
Sequence Identity: 25% (18 aa)

NNFQILSFGSFGMVLATKKAKLDKKEI--VLKIQKIEDE------QHIQNEISIMQKLKEPLVVQLYDSYI
|. |... |||| |   .  |. . .   |... .  |.      . |..|| || .|. . .| .| ...
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWL
Kinase 17269.AA STE-Unique 209-238 30 0.00087 8.67 In-house 514-543 (616) Show / Hide 
Range on Protein: 209-238
Range on HMM: 514-543/616
Sequence Identity: 30% (9 aa)

YSAPEILNKQDNELKVYSKKSDSYSVGLLL
| .||..|...   . |. |.|..| | ..
YMCPEVINCRNQINNPYDTKVDIWSLGCMC
Kinase 17269.AA STE 211-238 31 0.005647 6.49 In-house 230-258 (359) Show / Hide 
Range on Protein: 211-238
Range on HMM: 230-258/359
Sequence Identity: 31% (9 aa)

APEILNKQDNE-LKVYSKKSDSYSVGLLL
|||.......   | |. |.| .|.|...
APEVIQQNGQGRDKGYDTKCDIWSLGCTI
Kinase 17269.AA CAMK 209-238 35 0.00638 4.45 In-house 285-324 (425) Show / Hide 
Range on Protein: 209-238
Range on HMM: 285-324/425
Sequence Identity: 35% (14 aa)

YSA-PEILNKQ---------DNELKVYSKKSDSYSVGLLL
| | ||.||..         |.| . |..|.|  |.| .|
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase 17269.AA STE20 211-235 36 0.283958 0.77 In-house 190-214 (288) Show / Hide 
Range on Protein: 211-235
Range on HMM: 190-214/288
Sequence Identity: 36% (9 aa)

APEILNKQDNELKVYSKKSDSYSVG
|||....... .| |  |.| .|.|
APEVIQCMEGPDKGYDYKCDIWSLG