Gene 15974 (Tetrahymena)

15974

Species: Tetrahymena
Alias: 740, PreTt15974, 15974, 32.m00218, TTHERM_00321560
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C3

Sequence

Name Sequence Type Origin Length Description Download
15974.AA Protein None 1274 None Fasta, JSON
15974.kin_dom Protein Kinase Domain None 33 None Fasta, JSON
15974.NA RNA None 3825 None Fasta, JSON

Protein domain

Protein domains of 15974.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15974.AA Ciliate-C3 818-870 83 1.7e-27 95.02 In-house 1-52 (140) Show / Hide 
Range on Protein: 818-870
Range on HMM: 1-52/140
Sequence Identity: 83% (44 aa)

FIVKKVKLKGNQVSIVALKQPQEEEEKDYSQQQMREISILSNLPKNNLIIQYV
|||||||||.|. ..||||||| ||..|||.||||||||||||||||||||||
FIVKKVKLKENKDRKVALKQPQ-EEQNDYSKQQMREISILSNLPKNNLIIQYV
Kinase 15974.AA Ciliate-C3 871-903 87 2.3e-20 69.43 In-house 108-140 (140) Show / Hide 
Range on Protein: 871-903
Range on HMM: 108-140/140
Sequence Identity: 87% (29 aa)

AIEYLHEHNIVHGDIKLSNILINSSDKIKIIDF
||.|||||||||||||.||||||| |.||||||
AIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase 15974.AA AGC 871-903 45 3.2e-15 34.34 In-house 165-199 (395) Show / Hide 
Range on Protein: 871-903
Range on HMM: 165-199/395
Sequence Identity: 45% (16 aa)

AIEYLHE-HNIVHGD-IKLSNILINSSDKIKIIDF
|.||||. ..|.| | .|. |||...   ||. ||
ALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDF
Kinase 15974.AA MARK 871-903 57 1e-14 44.73 In-house 116-150 (262) Show / Hide 
Range on Protein: 871-903
Range on HMM: 116-150/262
Sequence Identity: 57% (20 aa)

AIEYLHEHNIVHGDIKLSNILINSSD--KIKIIDF
|..|.|..|||| |||. |||| .    .||||||
AVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDF
Kinase 15974.AA CAMKL 871-903 54 1.9e-14 42.39 In-house 139-173 (297) Show / Hide 
Range on Protein: 871-903
Range on HMM: 139-173/297
Sequence Identity: 54% (19 aa)

AIEYLHEHNIVHGDIKLSNILINSSD--KIKIIDF
|..|.|.|.||| |||. |||. ...  .||||||
AVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDF
Kinase 15974.AA CAMK 871-903 38 2.4e-13 38.63 In-house 191-240 (425) Show / Hide 
Range on Protein: 871-903
Range on HMM: 191-240/425
Sequence Identity: 38% (19 aa)

AIEYLHEHNIVHGDIKLSNILINSSD-----------------KIKIIDF
|..|.|.||||| |.|. |||.....                 .||||||
AVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase 15974.AA Ciliate-E8 871-906 55 3.2e-13 37.68 In-house 101-138 (138) Show / Hide 
Range on Protein: 871-906
Range on HMM: 101-138/138
Sequence Identity: 55% (21 aa)

AIEYLHEHNIVHGDIKLSNILINS--SDKIKIIDFSES
|. |||  ||.| |.|| |||.      |||||||  |
AFCYLHNNNIIHCDFKLNNILVQRNDDTKIKIIDFGFS
Kinase 15974.AA Ciliate-E2 870-1013 18 3.6e-13 41.53 In-house 171-360 (365) Show / Hide 
Range on Protein: 870-1013
Range on HMM: 171-360/365
Sequence Identity: 18% (40 aa)

VAIEYLHEHN-IVHGDIKLSNILINSSDKIKIIDFS------------------------------------------------ESGFLVEETIGYTEDY
.|.||||. | |.| |||..|||.     ||||||                                                   |..  | ... ...
LALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYD

-EAKDNFKTRYIDYYSLGILLIRIFYS-FKFKIRCNCKQEAKNCKMENHEEFILQAISKIDDEQ-------------RKNQYSQIFFDQIKS----LLND
 . | .  .  .|..|||..| .  .  . |                  .. |.|   ... ..              ... ||   | ||     .|. 
NQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQK

QPYLRCT-LKELI
.|  | |  ....
DPEKRITGWEQIL
Kinase 15974.AA AMPK 871-903 48 5e-12 32.06 In-house 112-144 (254) Show / Hide 
Range on Protein: 871-903
Range on HMM: 112-144/254
Sequence Identity: 48% (16 aa)

AIEYLHEHNIVHGDIKLSNILINSSDKIKIIDF
..||.|.|.||| | |. |.|..   .||| ||
GVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDF
Kinase 15974.AA Ciliate-E2-Unclassified 870-906 48 2.5e-11 35.55 In-house 154-194 (352) Show / Hide 
Range on Protein: 870-906
Range on HMM: 154-194/352
Sequence Identity: 48% (20 aa)

VAIEYLHEHN-IVHGDIKLSNILINSSD---KIKIIDFSES
...||||. | |.| |||..|||....    .||||||. |
QGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS
Kinase 15974.AA CMGC 871-903 28 3.6e-11 31.99 In-house 192-248 (513) Show / Hide 
Range on Protein: 871-903
Range on HMM: 192-248/513
Sequence Identity: 28% (16 aa)

AIE--YLHEHN--IVHGDIKLSNILINSS--------------------DKIKIIDF
...  |.| |.  |.| |.| .|||||.                     ...||.||
GLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDF
Kinase 15974.AA Pkinase 871-903 43 4.7e-10 36.64 Pfam 120-156 (293) Show / Hide 
Range on Protein: 871-903
Range on HMM: 120-156/293
Sequence Identity: 43% (16 aa)

AIEYLHEHNIVHGDIKLSNILINSSDKI----KIIDF
..||.|...|.| |.|..||||.. . |    ||.||
GLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDF
Kinase 15974.AA S_TKc 807-1016 19 2.1e-08 -53.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 807-1016
Range on HMM: 1-231/231
Sequence Identity: 19% (53 aa)

YDELENISSSQF-IVKKVKLKGNQVSIVALKQPQEEEEKDYSQQQMREISILSNLPKNNLIIQYV-----------------------------------
|. |. | .  |  |.|.. |.    |||.|.          .. .|||.||..  .   |...                                    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

----------------AIEYLHEHNIVHGDIKLSNILINSSDKIKIIDFSESGFLVEETIGYTEDY---EAKDNFKTRYIDYYSLGILLIRIFY-SFKFK
                |.||.|.|.|.| |.| .|||...   |||.||  . .|   |.  | .|   |    . .. .| .|.|..|.  ..    | 
FPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP

IRCNCKQEAKNCKMENHEEFILQAISKIDDEQRKNQYSQIFFDQIKSLLNDQPYLRCTLKELIY---------II
                ... ... |            |. . | |. .|.  |  | |  |.            .
----------------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15974.AA CMGC 807-866 16 0.112372 0.23 In-house 1-101 (513) Show / Hide 
Range on Protein: 807-866
Range on HMM: 1-101/513
Sequence Identity: 16% (17 aa)

YDELENISSSQF-IVKKVKLKGNQVS-------------IVALKQPQEEEEKDYSQ----------QQMREISILSNLP-----------------KNNL
|. .. | .  . .| | . | ..               |||.|   ......  .             |||.|| .|                  .||.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

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