Gene 15778 (Tetrahymena)
15778
Sequence
Protein domains of 15778.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 15778.AA | C8 | 46-155 | 54 | 4.2e-49 | 168.56 | In-house | 1-110 (226) | Show / Hide |
Range on Protein: 46-155 Range on HMM: 1-110/226 Sequence Identity: 54% (60 aa) FQNFEYLSSGAYSLVLKAYNSQQNRQVALKFLGSSNKEYNNGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQEDEDEDGNDIIVQTGVKSFFVMEME |.||.|||.|||..||||.|...||...|||. ..||. ...|||..|||||.|.|.|..|.||.|||||.|.|...|....|..|||| .||.|||||| FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME LCESKQKSHF |||.. | . LCEQNLKQLY |
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Kinase | 15778.AA | Ciliate-C8 | 55-155 | 56 | 8.6e-46 | 158.45 | In-house | 1-106 (238) | Show / Hide |
Range on Protein: 55-155 Range on HMM: 1-106/238 Sequence Identity: 56% (60 aa) GAYSLVLKAYNSQQNRQVALKFLGSSNKEYNNGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQEDEDEDGNDIIVQTGVK---SFFVMEMELCESK- ||...||||.|..|||.|||||. ..||. .|..|...|||||...|.|..|.|.||||||||||...||.||||.|||| .| ||||||||.|... GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC -QKSHF |. | NLKQYF |
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Kinase | 15778.AA | C2 | 55-155 | 35 | 1.2e-26 | 88.18 | In-house | 1-109 (245) | Show / Hide |
Range on Protein: 55-155 Range on HMM: 1-109/245 Sequence Identity: 35% (39 aa) GAYSLVLKAYNSQQNRQVALKFLGSSNKEYNNGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEE-QEDEDEDGNDIIVQTGV--------KSFFVMEME || .|||||.| .|||.|||| . || ... |||....... . ....||..||| .. .|||||| ...... |.|.|.|.| GAFGLVLKAFNKKQNRHVALKIQECQSNDI-NGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE LCESKQKSHF |... |. | FCQGNLKQYF |
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Kinase | 15778.AA | CMGC | 46-115 | 14 | 6.5e-08 | 21.1 | In-house | 1-108 (513) | Show / Hide |
Range on Protein: 46-115 Range on HMM: 1-108/513 Sequence Identity: 14% (16 aa) FQNFEYLSSGAYSLVLKAYN--------------SQQNRQVALKFLGSSNKEYNNGIE----------SLKKEYEMLQKFS----------------QSQ ... ... .|.|. | |... . |..||.| . .... | .. . | ..|.... . YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKI-KNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHN FLVNVYDCFY .|. ||.|| NIVKLYDIFY |
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Kinase | 15778.AA | STE20 | 46-119 | 19 | 9.8e-08 | 24.67 | In-house | 1-82 (288) | Show / Hide |
Range on Protein: 46-119 Range on HMM: 1-82/288 Sequence Identity: 19% (16 aa) FQNFEYLSSGAYSLVLKAYNSQQNRQ----VALKFLGSSNKEYN-NGIESLKKEYEMLQKFSQSQFLVNVYDCFYLM----EE ....| . .|.| | |||. . ... || | . .... . .|...||. ..... .. |. |.... . .| YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDE |
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Kinase | 15778.AA | STE | 46-123 | 17 | 3.5e-07 | 21.53 | In-house | 1-111 (359) | Show / Hide |
Range on Protein: 46-123 Range on HMM: 1-111/359 Sequence Identity: 17% (19 aa) FQNFEYLSSGAYSLVLKAYNS------QQNRQ---------VALKFLGSSNKE----------YNNG----IESLKKEYEMLQKFSQ-SQFLVNVYDCFY ... | . .||. | ||.| . ... .| | . .|.. ..| .....|| ....|... ... |. |.|.. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF LM---EEQEDE ....|| KEGHNHKNDDE |
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Kinase | 15778.AA | MAPK | 46-75 | 25 | 4.4e-07 | 20.28 | In-house | 1-36 (328) | Show / Hide |
Range on Protein: 46-75 Range on HMM: 1-36/328 Sequence Identity: 25% (9 aa) FQNFEYLSSGAYSLVLKAYNSQ------QNRQVALK .|. ... .||| .| .|. ....||.| YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK |
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Kinase | 15778.AA | Ciliate-E1 | 52-116 | 23 | 6.4e-07 | 19.06 | In-house | 1-66 (202) | Show / Hide |
Range on Protein: 52-116 Range on HMM: 1-66/202 Sequence Identity: 23% (16 aa) LSSGAYSLVLKAYNSQQN-RQVALKFLGSSNKEYNNGIESLKKEYE-MLQKFSQSQFLVNVYDCFYL ...| .|.|.||.. ..| .|||.|. .. | .....||| ... | . . .....|.... IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKI |
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Kinase | 15778.AA | ULK | 46-115 | 21 | 1e-06 | 19.96 | In-house | 1-85 (324) | Show / Hide |
Range on Protein: 46-115 Range on HMM: 1-85/324 Sequence Identity: 21% (18 aa) FQNFEYLSSGAYS-LVLKAYNSQQ---NRQVALKFLG---SSNKEYNNG----IESLKKEYEMLQKFS--QSQF--LVNVYDCFY .. . | .|.. | |..| .. | .|| | ..|.... ...||.| . ..|. .... | ||.|. YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFE |
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Kinase | 15778.AA | Ciliate-E3 | 46-115 | 24 | 1.1e-05 | 14.09 | In-house | 1-72 (202) | Show / Hide |
Range on Protein: 46-115 Range on HMM: 1-72/202 Sequence Identity: 24% (18 aa) FQNFEYLSSGAYSLVLKAYNSQQNRQVALKFLGSSNKEY---NNGIESLKKEYEMLQKFSQSQFLVNVYDCFY . | | ...| ||...|.|..|| | . .|. . .| . |.. ||..| ..| .| YTVQQILGCGQFGRVYKAFDFQNNQDVAIKAIICQNQQNEGVGEQFQKTQQEFQNCQQI-NSQNVVKCHDQYY |
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Kinase | 15778.AA | Pkinase | 46-115 | 16 | 0.00016 | 17.07 | Pfam | 1-70 (293) | Show / Hide |
Range on Protein: 46-115 Range on HMM: 1-70/293 Sequence Identity: 16% (12 aa) FQNFEYLSSGAYSLVLKAYNSQQNRQVALKFLGSSNKEYNNGIESLK-KEYEMLQKFSQSQFLVNVYDCFY .. . . ||... | |... ...||.| . .... . .. .. | ...... .. . | ||.|. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFE |