Gene 15035 (Tetrahymena)
15035
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 15035.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 15035.AA | Ciliate-E2 | 17-105 | 30 | 2.1e-21 | 70.24 | In-house | 253-365 (365) | Show / Hide |
Range on Protein: 17-105 Range on HMM: 253-365/365 Sequence Identity: 30% (35 aa) YVAPEIINYTG----RLSIDDYLKSDIYSLGIILYQLNFLSIPTQQQIDNILTTKLYID------------------SDISYGMMDLLQR----MLCKDP |.||||.|. . .. . |.||.|||.|||.. | | ...|. |. .. ..| ..||... ||.||| YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP LKRIT-AKQALVHQVF |||| ..|.| |. | EKRITGWEQILNHPWF |
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| Pkinase | 15035.AA | Pkinase | 14-105 | 25 | 1.1e-16 | 60.14 | Pfam | 174-293 (293) | Show / Hide |
Range on Protein: 14-105 Range on HMM: 174-293/293 Sequence Identity: 25% (31 aa) SLVYVAPEIINYTGRLSIDDYLKSDIYSLGIILYQLNFLSIPTQQQ-----------IDNILTTKLYIDSDIS---------------------YGMMDL .. |.|||.|. . .. |.|..|.|.|||.. . | ... |..|. ..| |.. . . |. TPWYMAPEVIR----GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF LQRMLCKDPLKRITAKQALVHQVF . ..||||| ||.||.|.| | | IKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 15035.AA | Ciliate-E2-Unclassified | 17-105 | 26 | 1.4e-16 | 54.06 | In-house | 228-352 (352) | Show / Hide |
Range on Protein: 17-105 Range on HMM: 228-352/352 Sequence Identity: 26% (34 aa) YV----APEII---NYTGRLSIDDYLKSDIYSLGIILYQLNFLSIPTQ---------------------QQIDNILTTKLYIDS--------DISYGMMD | |||.. || .. . |.||.|||.|||.. | | . |...||. ...... ..| | YMPQYTAPEVLQGQNYDHSKA----YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKD LLQ----RMLCKDPLKRITAKQALVHQVF ... .|| |.| ||||..|.| |. | FINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | 15035.AA | ULK | 14-105 | 26 | 3.7e-13 | 42.35 | In-house | 214-329 (329) | Show / Hide |
Range on Protein: 14-105 Range on HMM: 214-329/329 Sequence Identity: 26% (31 aa) SLVYVAPEIINYTGRLSIDDY-LKSDIYSLGIILYQLNFLSIP----TQQQI-----DN----------ILTTKLYIDSD-----ISYGMMDLLQRMLCK . | ||.|.. | .. | |.||.|||.|.|.. . | ..|. .. | ...| .. | || . ||..|||.. TPLYMAPQILQGQG-EQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQY DPLKRITAKQALVHQVF |. .||. . . | .| DEKDRISWEELFNHPWF |
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| Kinase | 15035.AA | CAMK | 14-105 | 22 | 5.2e-13 | 37.56 | In-house | 282-425 (425) | Show / Hide |
Range on Protein: 14-105 Range on HMM: 282-425/425 Sequence Identity: 22% (32 aa) SLVYVA-PEIINYTGRLSI-------DDY--LKSDIYSLGIILY-----QLNFLSIPTQQQID-------------NILTTKLY-I-------------- .. |.| ||..|. |. . .| |.|. |.|.||| . | . ..... .|.. | . . TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE -DSDISYG--------MMDLLQRMLCKDPLKRITAKQALVHQVF ..||| .||...||..|| ||.|..|.| |. . WWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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| Kinase | 15035.AA | Ciliate-E2a | 79-105 | 62 | 8.7e-13 | 33.99 | In-house | 249-275 (275) | Show / Hide |
Range on Protein: 79-105 Range on HMM: 249-275/275 Sequence Identity: 62% (17 aa) MDLLQRMLCKDPLKRITAKQALVHQVF .||...|| ||| |||||.||| |. | KDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 15035.AA | CAMKK-Unclassified | 36-105 | 32 | 2.7e-12 | 36.06 | In-house | 313-392 (392) | Show / Hide |
Range on Protein: 36-105 Range on HMM: 313-392/392 Sequence Identity: 32% (26 aa) KSDIYSLGIILYQLNFLSIPTQQQIDN------ILTTK--LYI--DSDISYGMMDLLQRMLCKDPLKRITAKQALVHQVF | || |||. .| . ..|.| . . .. |. . . . ...| . ||.|.|. |.| ||||..| |||. | KADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNPKKRITIDQMLVHPWF |
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| Kinase | 15035.AA | ULK | 14-105 | 26 | 2.8e-12 | 39.94 | In-house | 210-324 (324) | Show / Hide |
Range on Protein: 14-105 Range on HMM: 210-324/324 Sequence Identity: 26% (31 aa) SLVYVAPEIINYTGRLSIDDY-LKSDIYSLGIILYQLNFLSIP-----TQQQ------IDN-------ILTTKLYID-----SDISYGMMDLLQRMLCKD . | ||.|.. | .. | |.||.|||.|.|.. . . | ..|. |.| | .... .. || . ||..|||..| TPLYMAPQILQGQG-EQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYD PLKRITAKQALVHQVF . .||. . . | .| EKDRISWEEIFNHPWF |
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| Kinase | 15035.AA | AGC | 17-105 | 21 | 3.9e-12 | 26.18 | In-house | 273-395 (395) | Show / Hide |
Range on Protein: 17-105 Range on HMM: 273-395/395 Sequence Identity: 21% (28 aa) YVAPEIINYTGRLSIDDYLKS-DIYS--LGIILYQLNFLSIP---------------TQQQIDNIL------TTKLYID----------SDISYGMMDLL |.||||. | |. |..| ||...|.. . | . ..|. . |. .. . .| .||. YMAPEIL----------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLI QRMLCKDPLKRIT----------AKQALVHQVF ...||||| ||.. |.. | | KKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 15035.AA | CDC2 | 79-105 | 59 | 7.2e-12 | 32.23 | In-house | 275-301 (301) | Show / Hide |
Range on Protein: 79-105 Range on HMM: 275-301/301 Sequence Identity: 59% (16 aa) MDLLQRMLCKDPLKRITAKQALVHQVF .|||..||. || |||.||.|| | | IDLLMQMLQYDPQKRISAKEALQHPYF |
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| Kinase | 15035.AA | RCK | 72-105 | 47 | 1.4e-11 | 32.73 | In-house | 265-298 (298) | Show / Hide |
Range on Protein: 72-105 Range on HMM: 265-298/298 Sequence Identity: 47% (16 aa) SDISYGMMDLLQRMLCKDPLKRITAKQALVHQVF ...|. ...|.. ||. || |||||.||| |. | PNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF |
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| Kinase | 15035.AA | Ciliate-E2a | 17-49 | 44 | 1.8e-05 | 12.07 | In-house | 176-209 (275) | Show / Hide |
Range on Protein: 17-49 Range on HMM: 176-209/275 Sequence Identity: 44% (15 aa) YVAPEIINYTGRLSIDDY-LKSDIYSLGIILYQL |||||..|. |. .| | |. |.|.|.| | YVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYIL |
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