Gene 14297 (Tetrahymena)

14297

Species: Tetrahymena
Alias: 2.m02447, TTHERM_00031650, 3825.m02681, 14297, 167, PreTt14297
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
14297.AA Protein None 1349 None Fasta, JSON
14297.kin_dom Protein Kinase Domain None 33 None Fasta, JSON
14297.NA RNA None 4050 None Fasta, JSON

Protein domain

Protein domains of 14297.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 14297.AA Ciliate-E2 236-340 20 2.3e-12 38.73 In-house 252-365 (365) Show / Hide 
Range on Protein: 236-340
Range on HMM: 252-365/365
Sequence Identity: 20% (26 aa)

EYIAPETLKHKK---------ITQQSNLWSVGCIFYEMLFNEK-FMEINAEKASTKEGLSEYYQ-QVKYSSE--TLRSTLICK------STTISNFSITC
.| ||| |. ||          . .. .||.|.|.|||||..  |             . .  | .......  ... |. |.         .|.  .  
GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------------QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDL

LLG----LLAFHEKDRYN-WEQVKKNIFS
.      .|   .. |.. |||.... . 
IKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 14297.AA AGC 236-266 42 2e-10 21.63 In-house 272-300 (395) Show / Hide 
Range on Protein: 236-266
Range on HMM: 272-300/395
Sequence Identity: 42% (14 aa)

EYIAPETLKHKKITQQSNLWS--VGCIFYEMLF
||.||| |     ...   ||  .||..||||.
EYMAPEIL----YGKACDWWSFGLGCLMYEMLT
S_TKc 14297.AA S_TKc 45-340 12 5.6e-09 -45.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 45-340
Range on HMM: 1-231/231
Sequence Identity: 12% (43 aa)

IILESQIAGDSAQKTYKCQMNENNERIGFVKVYNKNKLELYSNGKLVIQRARHSIDILQNFSRQSANWIPQLLNHQEDDDNIEIITEYVQD---NINEMI
  .  .|   .  | |||. ..   ||  .|. .              ...|  |.||..       .| .|. . .| |.. ...||.     .  ..|
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI

EQKQI------YSENDAIYLMKCILMSLNEMHNIKNVF---------------------NAEECYLNIAIHPKFLLFKQQNGLLSDAKKDIILFSNAGDL
....       ..| .| ..|. |.  |. .|.  ..                       | .                                     
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDEHIKICDFGLARQL------------------------------------

FQEEDLKKKNTKEIEQLIKINEYIAPETLKHKKITQ-QSNLWSVGCIFYEMLFNEKFMEINAEKASTKEGLSEYYQQVKYSSETLRSTLICKSTTISNFS
                ..   .|.||| |   . .   .  ||.|||.||||  .   .           . . .....                 |   
--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP----------QMQMMFKKIG-----------------SPEA

ITCLLGLLAFHEKDRYNWEQVKK-------NIFS
.  . ..| .  ..|.   .. .         . 
KDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 14297.AA NDR 236-266 46 1.6e-08 21.68 In-house 246-277 (350) Show / Hide 
Range on Protein: 236-266
Range on HMM: 246-277/350
Sequence Identity: 46% (15 aa)

EYIAPETLKHKK-ITQQSNLWSVGCIFYEMLF
.|.||| .. |.  .|.   ||.|||.||||.
DYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLV
Kinase 14297.AA Ciliate-E2-Unclassified 235-268 33 5.4e-08 23.83 In-house 226-267 (352) Show / Hide 
Range on Protein: 235-268
Range on HMM: 226-267/352
Sequence Identity: 33% (14 aa)

NEYI----APETLKHKKITQQ----SNLWSVGCIFYEMLFNE
..|.    ||| |. ..  ..    .  ||.|.|.|||||..
PNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY
Kinase 14297.AA Pkinase 236-268 38 2e-06 24.06 Pfam 176-209 (293) Show / Hide 
Range on Protein: 236-268
Range on HMM: 176-209/293
Sequence Identity: 38% (13 aa)

EYIAPETLK-HKKITQQSNLWSVGCIFYEMLFNE
.|.||| .. ...... .  ||.|||.||||. .
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase 14297.AA Akt 236-266 40 2e-06 16.85 In-house 167-198 (264) Show / Hide 
Range on Protein: 236-266
Range on HMM: 167-198/264
Sequence Identity: 40% (13 aa)

EYIAPETLKHKKITQQSNLWS-VGCIFYEMLF
||.||| |. .  |...  |. .||..|||..
EYLAPEILNGNGHTKAVDWWGSLGCVMYEMMC
Kinase 14297.AA ULK 237-268 40 2e-06 19.1 In-house 291-327 (324) Show / Hide 
Range on Protein: 237-268
Range on HMM: 291-327/324
Sequence Identity: 40% (15 aa)

YIAPETLK----HKKIT-QQSNLWSVGCIFYEMLFNE
| ||. |.    .|. .   . .||.||||||||...
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGK
Kinase 14297.AA ULK 237-268 40 2e-06 18.82 In-house 217-253 (329) Show / Hide 
Range on Protein: 237-268
Range on HMM: 217-253/329
Sequence Identity: 40% (15 aa)

YIAPETLK----HKKIT-QQSNLWSVGCIFYEMLFNE
| ||. |.    .|. .   . .||.||||||||...
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGK
Kinase 14297.AA NEK11 237-264 50 3e-06 18.9 In-house 170-197 (259) Show / Hide 
Range on Protein: 237-264
Range on HMM: 170-197/259
Sequence Identity: 50% (14 aa)

YIAPETLKHKKITQQSNLWSVGCIFYEM
|..|| |||.    .| .||. || |||
YMSPEALKHQGYDTKSDIWSLACILYEM
Kinase 14297.AA CAMK-Unique 121-170 15 7e-06 15.16 In-house 90-177 (363) Show / Hide 
Range on Protein: 121-170
Range on HMM: 90-177/363
Sequence Identity: 15% (14 aa)

EDDD---------------NIEIITEYVQDN-INEMIEQ--------------------KQIYSE--NDAIYLMKCILMSLNEMHNIK
.|..               .. |..||.|..  .. | .                    ....||  .|.. .| |.|. .. ||...
CDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQD
Kinase 14297.AA NZAK 236-264 37 8e-06 15.03 In-house 237-265 (329) Show / Hide 
Range on Protein: 236-264
Range on HMM: 237-265/329
Sequence Identity: 37% (11 aa)

EYIAPETLKHKKITQQSNLWSVGCIFYEM
.| ||| ..  .|.. |  || ||.  .|
HYMAPENKNNHRINEKSDVWSFGCTVWQM
Kinase 14297.AA CAMK-Unique 236-266 26 7.9e-05 11.65 In-house 240-288 (363) Show / Hide 
Range on Protein: 236-266
Range on HMM: 240-288/363
Sequence Identity: 26% (13 aa)

EYIAP--------------ETLKHKKITQQS----NLWSVGCIFYEMLF
.|.||              |...  .. ||.     .|| | | |.||.
CYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLC
Kinase 14297.AA NZAK 113-145 27 0.014609 3.85 In-house 60-99 (329) Show / Hide 
Range on Protein: 113-145
Range on HMM: 60-99/329
Sequence Identity: 27% (11 aa)

IPQLLN----HQEDDDNIEIITEYVQ-DNINEMI--EQKQ
||. .     | ||| .. |. |..  .|. ...  ..||
IPRYYSACIKHAEDDNYHCIYMEWMEGGNLTQFLMNDKKQ
Kinase 14297.AA ULK 317-340 29 0.051783 2.92 In-house 306-329 (329) Show / Hide 
Range on Protein: 317-340
Range on HMM: 306-329/329
Sequence Identity: 29% (7 aa)

LLGLLAFHEKDRYNWEQVKKNIFS
. ..| . |||| .||.. .. . 
IRRMLQYDEKDRISWEELFNHPWF
Kinase 14297.AA ULK 317-340 29 0.070655 2.52 In-house 301-324 (324) Show / Hide 
Range on Protein: 317-340
Range on HMM: 301-324/324
Sequence Identity: 29% (7 aa)

LLGLLAFHEKDRYNWEQVKKNIFS
. ..| . |||| .||.. .. . 
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 14297.AA Pkinase 121-160 24 1.131869 3.46 Pfam 70-118 (293) Show / Hide 
Range on Protein: 121-160
Range on HMM: 70-118/293
Sequence Identity: 24% (12 aa)

EDDDNIEIITEYVQD-----NINEMIE--QKQIY--SENDAIYLMKCIL
||.|.| ...||..         ..|.  ..  .  ||....  |. ||
EDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQIL