15452

Species: Tetrahymena
Alias: 52.m00230, 15452, PreTt15452, 3811.m00988, 234, TTHERM_00449390
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C6

Sequence

Name Sequence Type Origin Length Description Download
15452.AA Protein None 507 None Fasta, JSON
15452.NA RNA None 1524 None Fasta, JSON
15452.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of 15452.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15452.AA Ciliate-C6 221-491 67 5e-206 690.73 In-house 1-306 (306) Show / Hide
Range on Protein: 221-491
Range on HMM: 1-306/306
Sequence Identity: 67% (207 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQNMPDYYACKQIHISQDG--ENQSQQIFHEIEVLEKLKKYEYVIKLQNYIIE-ERSAYLVLDLAESTL
.|||||.|.||||||||.|||.||||||.||||.|||||||||||..|..  |||..||||||||||||||||.|||.|||.|| .|..|.|||||||||
INYRDSLGSGSFGQVYKCKNKHKQIIKNMDILQQMPDYYACKQIHMTQQMSFENQMSQIFHEIEVLEKLKKYENVIKMQNYFIEPNRQTYIVLDLAESTL

QDKINEKQAN------------------SEKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIKDD--NFYLSDFGCAEILFESQEARNN-LVM
||.|..||||                  .|.|||.|||.|..|||||||.||.|..|||||||||||||.||  |.||||||||. ||.|...||| ..|
QDCIQMKQANVNNFYFKQEINIFSFNYKYEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLFQSEFTRNNDIHM

GTLKWMSPELKEMKK----------NQVVDYFKSDIFSLGMLLLYMLTLSDISSVNSDEFTKNQKIRIMKNYCKGIS-NEIILLIKRMLETNPDNRPDAA
||||||||||.||||          ||..||||.|||||||.|||||||||||.||.|||.||||||||||.||.|| .|||.|...|||||||.|||..
GTLKWMSPELREMKKQYNQHQDDNSNQQIDYFKCDIFSLGMILLYMLTLSDISQVNCDEFMKNQKIRIMKNMCKDISYKEIIKLVSKMLETNPDHRPDMS

IIINAI
|.|..|
ILIQTI

Kinase 15452.AA Pkinase 221-491 21 1e-37 134.47 Pfam 1-293 (293) Show / Hide
Range on Protein: 221-491
Range on HMM: 1-293/293
Sequence Identity: 21% (67 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQNMPDYYACKQIHISQDGENQSQQIFH--EIEVLEKLKKYEYVIKLQNYIIEERSAYLVLDLAES---
.     || ||||.||| ..|  ..             .|.|.|  . . ... |. ..  ||... .| . .....|  .  .... |.|....|    
YHIGRKIGSGSFGCVYKCHHKGTGK------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLY

--TLQDKIN--EKQANSEKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIK-DDNF----YLSDFGCAEIL-FESQEARNNLVMGTLKWMSPE
   | | |   .. . .  |.| |. ... || . |. ..  .|| |||.||.||||. ...      ..|||.|. .   ...  . .. ||. .|.||
VMDLFDYISTWRHGCFY--FSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC-GTPWYMAPE

LKEMKKN-QVVDYFKSDIFSLGMLLLYMLT----LSDI----SSVNSDEFTKNQKIRIMKNYCK--------------------GISNEIILLIKRMLET
.     . .  .  |.|..|.| .| .||.     ..     . .. ..  .. . .. .  .                      .| | . .||..|. 
V----IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

NPDNRPDAAIIINA--I
.|  || |. | .   .
DPKKRPTAEQILQHPWF

Kinase 15452.AA S_TKc 221-499 23 1.6e-33 118.58 SMART 1-231 (231) Show / Hide
Range on Protein: 221-499
Range on HMM: 1-231/231
Sequence Identity: 23% (68 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQNMPDYYACKQIHISQDGENQSQQIFHEIEVLEKLKKYEYVIKLQNYIIEERSAYLVLDLAES---TL
    . || |.||.|||...|                ..|.|.|.         ..|  ||..|.|  . ....||  .. .  . |.|.....    .|
YEILRKIGKGAFGKVYKCRHKK------------TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDL

QDKINEKQANS--EKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIKDDNFYLSDFGCAEILFESQEARNNLVMGTLKWMSPELKEMKKNQVV
 | | ... .    .|.| .. ... || . |. .    || |||.||.|||. . .  ..||| | .|        . . ||. .|.||.         
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-HIKICDFGLARQL--------TTFCGTPWYMAPEVL------GY

DYFKSDIFSLGMLLLYMLT----LSDISSVNSDEFTKNQKIRIMKNYCKGISNEIILLIKRMLETNPDNRPDAAIIINAIQDIE-NNFK
...|.|. |.| .|  ||.     .             |  ...|. .   | | . .|...|. .|..|| |  . .. .||    . 
GKCKCDWWSCGCILYEMLCGYPPFP-------------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 15452.AA Ciliate-E2 221-489 21 1.5e-28 95.1 In-house 1-361 (365) Show / Hide
Range on Protein: 221-489
Range on HMM: 1-361/365
Sequence Identity: 21% (78 aa)

LNYRDSIGCGSFG-----QVYKVKNKYKQIIKNPDILQNMP---DYYACKQIHISQDGENQSQQIFHEIEVLEKLK---------------KYEYVIKLQ
 .    || |.||     .|.||....  .|.. ...   .   .... |.. . .  .|| .||. || .. ...               .  ..||. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

NYII--EERSAYLVLDLAES-TLQDKINEKQANS-------EKFDESEIVKFLSQIGKTL-------------ALIYIEE-G-IAHRDIKPSNILIKDDN
 . .   . . |||.....  .|.| |.... ..       ..|.| || ..  || .               || |. . . | ||||||.|||.    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

FYLSDFGCAEILFESQEARN------------------------------NLVMGTLKWMSPELKEMKK-----NQVVDYFKSDIFSLGMLLLYMLTL--
  ..||| . .. .... |                               | . ||.  |.||  ..||     .|    .|.||.|||..| .||.   
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

--SDISSVNSDEFTKNQKIRIMKNYCK--------GISNEIILLIKR----MLETNPDNRPD-AAIIIN
   ..   .  .| .....   .. |.         .|.| . |||.    ||. .|..|.. .  |.|
PFQQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN

Kinase 15452.AA STE 221-484 20 1.9e-28 97.62 In-house 1-348 (359) Show / Hide
Range on Protein: 221-484
Range on HMM: 1-348/359
Sequence Identity: 20% (72 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQ----NMPDYYACKQIHISQDG---------------ENQSQQIFHEIEVLEKLKK-YEYVIKLQNYI
.   . || |.||.||| .|. . .|  .   .    .. ...| ||......                ... ||| .||... |...  ....|   . 
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

IEER-------SAYLVLDLAE-STLQDKINEK----QANS------EKFDESEIVKFLSQIGKTLA-LIYIE-EGIAHRDIKPSNILIKDDNFYLSDFGC
. |        . .... . .  .| | |..|    . ..       .|.||.| ... ||    . | |..  .| ||||||.|||.      |.|||.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQI--LKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGV

AEILFES--------------QEA-RNNLVMGTLKWMSPELKEMKKNQ-VVDY-FKSDIFSLGMLL-------LYMLTLSDISSVNSDEFTK--------
. .| .|                . ..| . ||  ||.||  .  ..  . .| .|.|| ||| ..         . .... .      | .        
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----NQKIRIMKNYC---------------KGISNEIILLIKRMLETNPDNRPDA
     ..  ..  . .               .  | | .  |.. |. .|..||.|
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTA

Kinase 15452.AA ULK 219-481 22 1.5e-27 94.85 In-house 1-312 (324) Show / Hide
Range on Protein: 219-481
Range on HMM: 1-312/324
Sequence Identity: 22% (72 aa)

YELNYRDSIGCGSFG-QVYKVKNKYKQIIKNPDILQNMPDYYACKQIHISQDGENQSQ--------QIFHEIEVLEKLK--KYEY--VIKLQNYIIEE--
|.|| .  .| |||| .||| .|| ..             |.|||.| ...  .....        ..  ||... |||  | ..  ..||  .  .   
YCLNHC--LGKGSFGVKVYKGRNKKTNT---------QNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH

RSAYLVLDLAES-TLQDKINEKQA-----NSEKFDESEIVKFLSQIGKTLALIYI-EEGIAHRDIKPSNILIKDDNFY-------------LSDFGCAEI
   |..... .  .|.. |....      .  .. |.|...|. ||    .. .. ...| ||||||.||||.... .             ..||| | .
NNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQI--CNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKH

LFE-SQEARNN-------LVMGTLKWMSPELKEMK-KNQVVDYFKSDIFSLGMLLLYMLTLS------DISSV--NSDEFTK-------NQKIRIMKN--
... ..|.  .       .. ||   |.|.. . . ...  . .|.||.|||... .||. .        . .  . ..  .        ..  | ..  
VDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKP

-YCKGISNEIILLIKRMLETNPDNR
 . . ||.|.. ||.|||. ... |
PKDPKISPECKDLIRRMLQYDEKDR

Kinase 15452.AA ULK 219-481 22 8.3e-26 87.13 In-house 1-317 (329) Show / Hide
Range on Protein: 219-481
Range on HMM: 1-317/329
Sequence Identity: 22% (74 aa)

YELNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQNMPDYYACKQIH---ISQDGEN-----QSQQIFHEIEVLEKLK-------KYEYVIKLQNYIIEE
|.|| .  .| ||||.||    | . .... |  .|   ..|||.|    ..|.  .     . |..  ||... |||       . ....||  .  . 
YCLNHC--LGKGSFGKVY----KGRNKKTK-D-YVN--EKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETS

--RSAYLVLDLAES-TLQDKINEKQA------NSEKFDESEIVKFLSQIGKTLALIYI-EEGIAHRDIKPSNILIKDDNFY-------------LSDFGC
     |..... .  .|.. |....       .  .. |.|...|. ||    .. .. ...| ||||||.||||.... .             ..||| 
NHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQI--LNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGF

AEILFES--QEARNNLVM------GTLKWMSPELKEMK-KNQVVDYFKSDIFSLGMLLLYMLT------LSDISSVNSDEFTKNQKIR------IMKNYC
|  . ..  ... .          ||   |.|.. . . ...  . .|.||.|||... .||.       . ... .    .|. ...      | |.  
AKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPL

K----G----ISNEIILLIKRMLETNPDNR
.    |    ||.|.. ||.|||. ... |
QFPKDGNDPQISPECKDLIRRMLQYDEKDR

Kinase 15452.AA CAMK 226-434 18 1.7e-24 75.19 In-house 1-329 (425) Show / Hide
Range on Protein: 226-434
Range on HMM: 1-329/425
Sequence Identity: 18% (63 aa)

SIGCGSFGQVYKVKNK-YKQIIKNPDILQNMPDYYACKQIHIS----------------QDGENQS----------QQIFHEIEVLEKLKK------YEY
 .| ||||.|.....|  .. ..   |. | .  .|.| |  .                .. ....          .....|||.. ||..       . 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

VIKLQNYIIE-------------------ERSAYLVL---DLAEST-----LQDKINEKQANSEK-----------FDESEIVKFLSQIGKTLALIYIEE
.|||  ..                     ..  |.|.   ....       | |.| |.  ..|.           |.|.|  ..  ||    |. |. .
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQI--CSAVHYCHS

-GIAHRDIKPSNILIKDDNF---------------Y---LSDFGCAEILFESQEARNN----------------------LVMGTLKWMS-PELKEMKK-
 .|.|||.|| |||. |.|                .   ..||| | ....... ...                       . ||.  |. ||. . |. 
HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-------NQVVDY--FKSDIFSLGMLLLYMLT
       ..  .|  .|.|. |.| .|  ||.
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLC

Kinase 15452.AA Ciliate-E1 227-423 24 2.1e-20 63.38 In-house 1-202 (202) Show / Hide
Range on Protein: 227-423
Range on HMM: 1-202/202
Sequence Identity: 24% (53 aa)

IGCGSFGQVYKVKNKYKQIIKNPDILQNMPDYYACKQIHISQDGENQSQQIFHEIE-VLEKLKKYEYVIKLQNYIIEERS--AYLVLDLAESTLQDKIN-
|| |||..|.| |..  ....  ....|.          . .. .|. |.. .|.  ... .||..|.|....||. . .   ...... . .|.|... 
IGNGSFSIVFKAKQQNNNYNQVAQKIINC----------CFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQN

--------EKQANSEKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILI-KDDNFYLSDFGCAEILFESQEARNNLVMGTLKWMSPELKE-----
        ..| |  .|.. ....   |. . |. ...  .| ||||||.|||| ...|. ..|||.. .| ..|.   .    | .  .|| .      
HNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQ-YNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQE

MKKNQVVDYFKSDIF
..||| ..| ||||.
HNKNQKINY-KSDIY

Kinase 15452.AA Ciliate-E2-Unclassified 219-484 18 3.2e-20 66.87 In-house 1-343 (352) Show / Hide
Range on Protein: 219-484
Range on HMM: 1-343/352
Sequence Identity: 18% (68 aa)

YELNYRDSIGCGSFGQVYKV---KNKYKQIIKNPDILQNMPDYYACKQIHISQDGENQSQQIFHEIEVLEKLKKYEYVI-----------------KLQN
|....   || |.||.|||.   |.|.....|           |..|.....|   .....|  |.. ....||   .                  ..  
YKIIKQ--IGQGGFGKVYKCQHKKQKQYYAMK-----------YMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKM

YIIEERS--AYLVLDLAES-TLQDKIN-------------EKQANSEKFDESEIV-----KFLSQIGKTLAL-IYIEEG-IAHRDIKPSNILIKDD----
. ...     |.|....|  .|.. |.             ... ....|.| ...     ... ||   ..|  ..... | ||||||.|||....    
FYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQI--LQGLEYLHHKNNIIHRDIKPENILFDNNGKNY

NFYLSDFGCAEILFES--------------QEARNNLVMGTLKWM----SPELKEMKKNQ---VVDYFKSDIFSLGMLLLYMLT-LSDISSVNSDE----
.  ..||| .  . ..              .. . . ..||.  |    .||. . ...        .|.||.|||..| .||.     .. |...    
YIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQL

------------FTKNQKIRIMKNYC-------KGISNEIILLIK----RMLETNPDNRPDA
            . .|.| .. .. .       |..|.| . .|.    .||. ||..|...
ITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITF

Kinase 15452.AA TKL 355-491 17 2.5e-18 62.59 In-house 160-364 (364) Show / Hide
Range on Protein: 355-491
Range on HMM: 160-364/364
Sequence Identity: 17% (36 aa)

GIAHRDIKPSNILIKDDN---------------FYLSDFGCAEILFES------------------QEARNNLVMGTLKWMSPEL--KEMKKNQVV----
.|.|||.|..|||.....                 ..||| .  ...|                  .. ... . ||. ||.||.  ..|. .. |    
PIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE

-----DYF-KSDIFSLGMLLLYMLTLSDISSVNSDEFTKNQK------IRIMKNY--------------------CKGISNEIILLIKRMLETNPDNRPD
     .|. |.|..| |..|  .||      . .|.    ..      . .|...                    |. .  ... |...  ...|..|| 
FCKGFEYSEKCDVYSFGIVLWEILTRCR---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPS

AAIIINAI
.  |.  .
FQEILKRL

Kinase 15452.AA NAK 221-379 24 2.4e-16 51.0 In-house 1-171 (299) Show / Hide
Range on Protein: 221-379
Range on HMM: 1-171/299
Sequence Identity: 24% (43 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQNMPDYYACKQIHISQDGENQSQQIFHEIEVLEKLKKYEYVIKLQNYIIEERS-------AYLVLDLA
.  .  .. | |..||.|.. |  .. |     . .. || | . |....|.. ... .|||...||.. ......  . |.||.       ..|.. . 
YTVEKYLAEGGFSYVYLVQDNYINHPDN---PNSNGEKYALKRM-ICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYC

ES-TLQDKINEKQ-ANSEKFDESEIVKFLSQIGKTLALI-YIEE--GIAHRDIKPSNILIK----DDNFYLSDFG
.  .|.| .|... ..  .| | ||....... . .. . ..    .|.|||||. |||..    |.|. | |||
CHGSLWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFG

Kinase 15452.AA TyrKc 221-491 15 1.6e-11 -36.29 SMART 1-280 (280) Show / Hide
Range on Protein: 221-491
Range on HMM: 1-280/280
Sequence Identity: 15% (47 aa)

LNYRDSIGCGSFGQVYKVKNKYKQIIKNPDILQNMPDYYACKQIHISQDGENQSQQIFHEIEVLEKL-KKYEYVIKLQNYIIEE-------RSAYLVLDL
.   . .|.| ||.||| . |                  | | .. .       . . .|.... || .. . ...|  .....          ..|. .
ITLGKKLGEGAFGEVYKGTWK---------------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEY

AE-----STLQDKINEKQANSEKFDESEIVKFLSQIGKTLALIYIEEGIAHRDIKPSNILIKDDN-FYLSDFGCAEILFES-------QEARNN---LVM
..     . |... ..       .  .. ..|  || .  . .    .. |||.   |.|.....    |||| .  . .        .  |        
MPHGDLKDYLRKHRPK-------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

--GTLKWMSPELKEMKKNQVVDYFKSDIFSLGMLL--LYMLTLSDISS-----VNSDEFTKNQKIRIMKNYCKG--------ISNEIILLIKRMLETNPD
    ..||.||      |  .  .|||..| | ..  .. .  .  .      .. .|  .. | . .    .          . |.  ..|.  . .|.
TMLPIRWMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

NRPDAAIIINAI
.||  . |.  .
DRPTFSEIHECF

Kinase 15452.AA NAK 463-491 31 9.9e-07 18.41 In-house 271-299 (299) Show / Hide
Range on Protein: 463-491
Range on HMM: 271-299/299
Sequence Identity: 31% (9 aa)

SNEIILLIKRMLETNPDNRPDAAIIINAI
|.... ||. ||...|..||. . ..| .
SQQMHDLIRYMLTPDPEQRPNIYQVLNQL

Kinase 15452.AA CAMK 460-489 26 0.00022 9.25 In-house 384-421 (425) Show / Hide
Range on Protein: 460-489
Range on HMM: 384-421/425
Sequence Identity: 26% (10 aa)

KGISNE--------IILLIKRMLETNPDNRPDAAIIIN
..||.|         . ||..||...|..|. .. . |
DDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN

Kinase 15452.AA TKL 227-239 69 0.021161 4.47 In-house 1-13 (364) Show / Hide
Range on Protein: 227-239
Range on HMM: 1-13/364
Sequence Identity: 69% (9 aa)

IGCGSFGQVYKVK
|| |.||.||| |
IGSGGFGEVYKGK