Gene 15362 (Tetrahymena)

15362

Species: Tetrahymena
Alias: 15362, TTHERM_01329990, 732, PreTt15362, 329.m00008
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C5

Sequence

Name Sequence Type Origin Length Description Download
15362.AA Protein None 603 None Fasta, JSON
15362.kin_dom Protein Kinase Domain None 101 None Fasta, JSON
15362.NA RNA None 1812 None Fasta, JSON

Protein domain

Protein domains of 15362.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15362.AA Ciliate-C5 202-322 88 5.1e-84 276.46 In-house 140-260 (260) Show / Hide 
Range on Protein: 202-322
Range on HMM: 140-260/260
Sequence Identity: 88% (107 aa)

DYGESKLFKEGSKTYNLKGFTRKYAAPEITDDNGFFKIQYDIYGLGIILLELTLGKFLEDGDCTFIRKGKLPNYLSKNALYQDINQIIIKMLEILPNNRI
|||||| ||.|||||.||||||||||||||||||||.|.|||||||||||||||||||||.||||||.||||||.||||||||||||||||||..|.|||
DYGESKSFKDGSKTYDLKGFTRKYAAPEITDDNGFFNIKYDIYGLGIILLELTLGKFLEDEDCTFIRNGKLPNYISKNALYQDINQIIIKMLEKMPQNRI

DSLGLTKQLNEVRLKLESQFI
||..|||||||.|||||||||
DSFELTKQLNELRLKLESQFI
Kinase 15362.AA Ciliate-C5 116-191 90 1.3e-51 168.04 In-house 1-76 (260) Show / Hide 
Range on Protein: 116-191
Range on HMM: 1-76/260
Sequence Identity: 90% (69 aa)

IYLTSYISQGGNGCVFEAKYNEEIVAVKCSKPKFQKIKEEEKIMKFLKDTPYVFKSIEEFLNEKKTKYYQISKKYQ
|||||||||||.||||||||||||||||||||.|.|||||||||| |||||||||||||||||||.|||||||.|.
IYLTSYISQGGFGCVFEAKYNEEIVAVKCSKPNFEKIKEEEKIMKLLKDTPYVFKSIEEFLNEKKSKYYQISKRYS
Kinase 15362.AA S_TKc 116-315 14 1.2e-07 -64.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 116-315
Range on HMM: 1-231/231
Sequence Identity: 14% (38 aa)

IYLTSYISQGGNGCVFEAKYNE--EIVAVKCSKPKFQKIKEEEKIMKFLKDTPYVFKSIEEFLNEKKTKYY-----------QISKKYQSQ---------
  .   | .|. |.|. .. ..  .|||.|. |   ..|. | .|.|   . |.. | .. | .   ...|              .  ...         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

--------------------------------ILILNLQ---GDYGESKLFKEGSKTYNLKGFTRKYAAPEITDDNGFFKI-QYDIYGLGIILLELTLGK
                                ||. . .   .| | ....       .    |. | |||.      .     |.. .|.|| |.  |.
PEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGY

FLEDGDCTFIRKGKLPNYLSKNALYQDINQIIIKMLEILPNNRIDSLGLTK----QLNEVRL
 . . .   . |  .          ..  ..| |.|.  |..|.    . .      .   .
PPFP-QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15362.AA Ciliate-B2 117-175 28 1e-06 11.68 In-house 2-69 (197) Show / Hide 
Range on Protein: 117-175
Range on HMM: 2-69/197
Sequence Identity: 28% (20 aa)

YLTSYISQGGNGCVFEAKYNEEI------VAVKCSKP----KFQKIKEEEKIMKFLKDTPYVFKSIEEF
||. || .|| | ..|  |  ..      .|.|          . | .| |||| .    .| | |. .
YLCKYINKGGCGFICEG-YKKHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMFEYNINVVKYIDHI
Kinase 15362.AA STKR 116-143 37 2e-06 16.64 In-house 1-32 (312) Show / Hide 
Range on Protein: 116-143
Range on HMM: 1-32/312
Sequence Identity: 37% (12 aa)

IYLTSYISQGGNGCVFEAKYNE----EIVAVK
| |.  | .|  |.|. .|...    | ||||
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVK
Kinase 15362.AA Ciliate-E3 201-254 35 3e-06 16.02 In-house 148-202 (202) Show / Hide 
Range on Protein: 201-254
Range on HMM: 148-202/202
Sequence Identity: 35% (20 aa)

GDYGESK-LFKEG--SKTYNLKGFTRKYAAPEITDDNGFFKIQYDIYGLGIILLELT
.| |||| | |.   . |.   |.|  |||||. .|.. ..   |.| .| ....| 
CDFGESKQLRKNKGHTHTQY-QGWTPFYAAPEQ-NDQQQISKESDYYSVGAVFCQLC
Kinase 15362.AA Type2 116-143 36 7e-06 15.22 In-house 1-33 (315) Show / Hide 
Range on Protein: 116-143
Range on HMM: 1-33/315
Sequence Identity: 36% (12 aa)

IYLTSYISQGGNGCVFEAKYNEE-----IVAVK
| |   |..|. |||. |.....     .||||
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVK
Kinase 15362.AA STE 117-168 18 7e-06 16.83 In-house 1-92 (359) Show / Hide 
Range on Protein: 117-168
Range on HMM: 1-92/359
Sequence Identity: 18% (17 aa)

YLT-SYISQGGNGCVFEAKYN-----------------EEIVAVKCSK---------------------PKFQKIKEEEKIMKFLKD-TPYV
.   . | .|. | |. |...                  ||.|.|  .                      ..|.|..| |||| ...  |..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNI
Kinase 15362.AA C8 202-250 24 8e-06 16.37 In-house 170-226 (226) Show / Hide 
Range on Protein: 202-250
Range on HMM: 170-226/226
Sequence Identity: 24% (14 aa)

DYGESKLFKEGSKTYNLKGF----TRKYAAPEITDD----NGFFKIQYDIYGLGIIL
| |..   ..  . .  | .    | .| ||||  .    . ...|| |.. .|..|
DFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 15362.AA TKL 122-160 20 2.1e-05 15.46 In-house 1-79 (364) Show / Hide 
Range on Protein: 122-160
Range on HMM: 1-79/364
Sequence Identity: 20% (16 aa)

ISQGGNGCVFEAKYNE----------EIVAVKCSKP------------------------------KFQKIKEEEKIMK
| .|| |.|. .|..           . ||||  |                               .|.. .|||  |.
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMM
Kinase 15362.AA Ciliate-B2 202-247 36 2.4e-05 8.43 In-house 147-197 (197) Show / Hide 
Range on Protein: 202-247
Range on HMM: 147-197/197
Sequence Identity: 36% (19 aa)

DYGESKLFKEGSKTYNLKGFTRKYAAPE-ITDD---NGFFKIQY--DIYGLG
|.| | . |      . |||| ||| || . .|       .|..  ||| .|
DFGISSIKK-DNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 15362.AA TKL-ciliate2 116-164 30 3.3e-05 12.68 In-house 1-46 (273) Show / Hide 
Range on Protein: 116-164
Range on HMM: 1-46/273
Sequence Identity: 30% (15 aa)

IYLTSYISQGGNGCVFEAKYNEEIVAVKCSKPKFQKIKEEE-KIMKFLKD
. .   |. || | .. ||. | .||||    ||.   ... .|  |. .
LEIQNKITEGGYGIIYKAKWREIVVAVK----KFKMDHDNQQQIRDFVNE
Kinase 15362.AA TKL 201-257 15 8.2e-05 13.28 In-house 196-286 (364) Show / Hide 
Range on Protein: 201-257
Range on HMM: 196-286/364
Sequence Identity: 15% (14 aa)

GDYGESKLFKEGSK-------------------TYNLKGFTRKYAAPEITDDNGFFKIQY---------------DIYGLGIILLELTLGK
.|.| |. ... ..                   | . .. |  . |||. .......  .               |.|  ||.| |.  ..
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC
Kinase 15362.AA Ciliate-E1 122-175 30 0.000202 10.84 In-house 10-73 (202) Show / Hide 
Range on Protein: 122-175
Range on HMM: 10-73/202
Sequence Identity: 30% (20 aa)

ISQGGNGCVFEA---KYNEEIVAVKCSKPKFQ--------KIKEEEKIMKFLKDTPYVFKSIEEF
|..|. . ||.|   ..|.. ||.|  . .|.        .|||. |||| .|   |... |. .
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYI
Kinase 15362.AA TyrKc 116-310 14 0.000747 -160.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 116-310
Range on HMM: 1-280/280
Sequence Identity: 14% (41 aa)

IYLTSYISQGGNGCVFEAKYNEEIVAVKCSK--PKFQKIKEEEKIMKFL-KDTPYVFK----SIEE------------------------FLNEKKTKYY
| |   .  |  | |...... . ||||. |     . . .| .||. | .. | . .     ...                        .| ... |  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

QISKKYQSQ--------------------------ILILNLQ----GDYGESKLFKEG------SKTY------NLKG-FTRKYAAPEITDDNGFFKIQY
 .. |   .                          .|. . .    .| | |.  ...      ...|      . |. .  .  |||   . | | .. 
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKS

DIYGLGIILLEL-TLGKFLEDG-------DCTFIRKGKLPNYLSKNAL---------YQDINQIIIKMLEILPNNRIDSLGLTKQL
|..  |. . |. |.|.    |       .   |.. |  ... . .           ... ||. .  .  |..|     . ...
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 15362.AA C8 120-183 29 0.014771 4.83 In-house 5-70 (226) Show / Hide 
Range on Protein: 120-183
Range on HMM: 5-70/226
Sequence Identity: 29% (20 aa)

SYISQGGNGCVFEAKYNEE--IVAVKCSKPKFQ-KIKEEEKIMKFLKDTPYVFKSIEEFLNEKKTKY
 |.|.|. | | .||  ..   .. |  | . . .|...|.||| .. .| ||.  . . ||....|
QYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYE-MPQVFQQYDFYVNEYDCFY
Kinase 15362.AA Ciliate-E1 186-244 25 0.021638 4.16 In-house 140-202 (202) Show / Hide 
Range on Protein: 186-244
Range on HMM: 140-202/202
Sequence Identity: 25% (17 aa)

ISKKYQSQILILNLQGDYGESKLFKEGSKT-YNLKGFTRKYAAPEIT-------DDNGFFKIQYDIY
| .. |  .....   | | ||..|. ..  .. ||.| .|. ||         ..|   ....|||
ILINNQ-GNYVYC---DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY